Strain Name: |
B6.Cg-Gpi1a Hbbd H1b/DehJ |
|---|---|
Stock Number: |
002074 |
Availability: | Repository-Cryopreserved |
General Terms and Conditions |
| Genes & Alleles | Gpi1; Gpi1a; H1; Hbb; Hbbd; ; |
Product Information
Strain Details
Type JAX® GEMM® Strain - Congenic Additional information on JAX® GEMM® Strains. Type JAX® GEMM® Strain - Minor Histocompatibility Congenic Type JAX® GEMM® Strain - Mutant Strain Species laboratory mouse Background Strain C57BL/6 Donor Strain Gpi1a: CAST/Ei via B6.CAST-Gpi1a/Ei; H1b Hbbd: BALB/cBy via B6.C-Tyrc H1b Hbbd Generation N11F33p Appearance
black
Related Genotype: a/a
Gene & Allele Details
| Allele Symbol | Gpi1a | ||
|---|---|---|---|
| Allele Name | a variant | ||
| Gene Symbol and Name | Gpi1, glucose phosphate isomerase 1 | ||
| Chromosome | 7 | ||
| Gene Common Name(s) | AMF; GNPI; Gpi-1; Gpi-1r; Gpi-1s; Gpi-1t; Gpi1-r; Gpi1-s; Gpi1-t; NLK; Org; PGI; PHI; SA-36; glucose phosphate isomerase 1, regulatory; glucose phosphate isomerase 1, structural; glucose phosphate isomerase 1, temporal; | ||
| Molecular Note | This allele determines a slower migrating variant of the encoded enzyme and occurs in the wild and in strains A/HeJ, AKR/J, BALB/cJ, C57BR/cdJ, C58/J, CE/J, DBA/2J, DE/J, DW/J, LP/J, MA/J, NZB, PL/J, P/J, RARF, RF/J, SJL/J, ST/bJ, and 129/J. Sequencing analysis identified four nucleotide differences between this allele and Gpi1b. Two differences were silent, while a third difference at position 282 predicts an aspartate for the a allele and an asparagine for the b allele. A fourth difference in the 3' untranslated region was also noted. [MGI Ref ID J:28033] | ||
| Allele Symbol | Hbbd | ||
| Allele Name | d | ||
| Strain of Origin | BALB/c | ||
| Gene Symbol and Name | Hbb, hemoglobin beta chain complex | ||
| Chromosome | 7 | ||
| Gene Common Name(s) | CD113t-C; HBD; | ||
| Gene Symbol and Name | H1, histocompatibility 1 | ||
| Chromosome | 7 | ||
| Gene Common Name(s) | H-1; | ||
Related Strains
Strains carrying Gpi1a allele
000600 B6-Gpi1b x B6CBCa Aw-J/A-T(7;15)9H Gpi1a/J 000377 B6.C-H22c Gpi1a/(HW38)ByJ 000123 B6.C-H24c Gpi1a/(HW54)ByJ 001622 B6.CAST-Gpi1a.Cg-Hbath-J 000797 B6.CAST-Gpi1a/EiJ 001317 B6.Cg-Igha Thy1a Gpi1a/J 000909 B6CBy-Gpi1a/Gpi1b/J or Gpi1a-m1/Gpi1b/J 002800 C3.Cg-Gpi1a/J View Strains carrying Gpi1a (8 strains)
000409 B10.129P-H1b Hbbd Tyrc Ea7a/(5M)oSnJ 000418 B10.129P-H1b Tyrc Hbbd/(5M)nSnJ 000432 B10.C-H1b Hbbd Tyrc/(41N)SnJ 000383 B6.C-Tyrc H1b Hbbd/ByJ
Additional Web Information
Congenic Nomenclature
Research Applications
This mouse can be used to support research in many areas including:Gpi1a related
Hbbd relatedImmunology and Inflammation Research
CD Antigens, Antigen Receptors, and Histocompatibility Markers
Research Tools
Genetics Research (Tissue/Cell Markers)
Hematological Research
Hemoglobin Defects
Mouse/Human Gene Homologs
thalassemia, beta
References
Additional ReferencesPrice and Supply Information
| Strain Name: | B6.Cg-Gpi1a Hbbd H1b/DehJ |
| Stock Number: | 002074 |
Price Details
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Supply Details
| Standard Supply | Repository-Cryopreserved. Must Be Recovered. Please refer to pricing and supply notes for further information. |
|---|---|
| Supply Notes |
Cryorecovery - Standard. The recovery process begins when a signed agreement form is returned to the Customer Service Department after order placement. Although results vary by strain, at least two males and two females (two pairs) will be provided, typically within 15 weeks of our receipt of the signed agreement form. If the first recovery attempt is unsuccessful or only one pair is recovered, a second recovery will be done, extending the delivery time to approximately 25 weeks. At least one member of each pair will be of known genotype and will carry the mutation if it is a mutant strain. Please note that pairs may not reflect the mating scheme utilized by The Jackson Laboratory prior to cryopreservation of the strain. Mating schemes are sometimes modified for successful cryopreservation. Price represents a repository maintenance fee, which includes the cost of recovery of the strain from the cryopreservation resource and the periodic replacement of the frozen embryos used for recovery. Cryorecovery to establish a Dedicated Supply for greater quantities of mice. |
| Licensing | See General Terms and Conditions below |
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The Jackson Laboratory's Genotype Promise
The Jackson Laboratory has rigorous genetic quality control and mutant gene genotyping programs to ensure the genetic background of JAX® Mice strains as well as the genotypes of strains with identified molecular mutations. JAX® Mice strains are only made available to researchers after meeting our standards. However, the phenotype of each strain may not be fully characterized and/or captured in the strain data sheets. Therefore, we cannot guarantee a strain's phenotype will meet all expectations. To ensure that JAX® Mice will meet the needs of individual research projects or when requesting a strain that is new to your research, we suggest ordering and performing tests on a small number of mice to determine suitability for your particular project.Ordering and Purchasing Information
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