Strain Name: |
STOCK 11R30m/J |
|---|---|
Stock Number: |
002142 |
Availability: | Repository-Cryopreserved |
Price and Supply Information | |
General Terms and Conditions |
| Genes & Alleles | Tyrp1; Tyrp1b-11R30M; |
Type Deletion Additional information on Mice with Chromosomal Aberrations. Type JAX® GEMM® Strain - Mutant Stock Additional information on JAX® GEMM® Strains. Species laboratory mouse
Mammalian Phenotype Terms assigned by genotype |
| Allele Symbol | Tyrp1b-11R30M | ||
|---|---|---|---|
| Allele Name | brown 11R30M | ||
| Common Name(s) | b11R30M; | ||
| Strain of Origin | (101/Rl x C3H/Rl)F1 | ||
| Gene Symbol and Name | Tyrp1, tyrosinase-related protein 1 | ||
| Chromosome | 4 | ||
| Gene Common Name(s) | B; CAS2; CATB; GP75; TRP; TRP-1; TRP1; TYRP; Tyrp; b; b-PROTEIN; brown; iris stromal atrophy; isa; tyrosinase-related protein; | ||
| Molecular Note | Large intergenic deletion. | ||
Deletion
005535 B6.129S7-Del(11Cops3-Zfp179)1Jrl/J 003374 B6;129S2-H2dlAb1-Ea/J 005654 B6C3-Del(16Cbr1-ORF9)1Rhr/J 002802 C3.BLiA Pde6b+-Krd/J 004406 C3HeB/FeJ-Pou3f4del-J/J 004711 STOCK Ednrbs-52Pub View Deletion (6 strains)
Strains carrying other alleles of Tyrp1
000004 ABP/LeJ 000571 B6.Cg-Whrnwi Tyrp1b/+ +/J 000027 B6.D-Tyrp1b m/J 000068 C57BL/6J-Tyrp1b-J/J 000093 C57BL/6J-Tyrp1b-cJ/J 000670 DBA/1J 000671 DBA/2J 003588 LT/SvEi 006252 LT/SvEiJ 000265 MY/HuLeJ 001045 SI/Col Tyrp1b Dnahc11iv/J 000064 STOCK a Tyrp1b Sisi/J 002238 STOCK a Tyrp1b shmy/J 001432 STOCK a/a Tyrp1b sks/Tyrp1b +/J 000594 STOCK T(2;8)26H a/T(2;8)26H a Tyrp1+/Tyrp1b/J 001101 STOCK T(3;4)5Rk Tyrp1b/J 000274 TSJ/LeJ View Strains carrying other alleles of Tyrp1 (17 strains)
Selected Reference(s)
Additional ReferencesRinchik EM; Johnson DK; Margolis FL; Jackson IJ; Russell LB; Carpenter DA. 1991. Reverse genetics in the mouse and its application to the study of deafness. Ann N Y Acad Sci 630:80-92. [PubMed: 1952626] [MGI Ref ID J:73419]
| Strain Name: | STOCK 11R30m/J |
| Stock Number: | 002142 |
IMPORTANT NOTE: Prices are based on shipping destination. The shipping destinations are:
| Price(s) in US dollars ($) | |||||
|---|---|---|---|---|---|
| Cryorecovery Fee | $2470.00 | ||||
| Standard Supply | Repository-Cryopreserved. Must Be Recovered. Please refer to pricing and supply notes for further information. |
|---|---|
| Supply Notes |
Cryorecovery of Strains Needing Progeny Testing. The recovery process begins when a signed agreement form is returned to the Customer Service Department after order placement. Although results vary by strain, at least two untested males and two untested females (two pairs) will be recovered, typically within 15 weeks of our receipt of the signed agreement form. If the first recovery attempt is unsuccessful or only one pair is recovered, a second recovery will be done, extending the overall recovery time to approximately 25 weeks. However, all pups recovered will be sent. Progeny testing is required to identify the genotype of mice of this strain, as a genotyping assay is not available. This type of testing involves breeding the recovered animals and assessing the phenotype of the offspring in order to identify animals carrying the mutation of interest. We can perform the progeny testing for you as a service or we can ship all recovered animals (at least two untested pairs) to you for progeny testing at your facility. If you perform the progeny testing, there is NO guarantee that a carrier will be identified. If we perform progeny testing as a service, additional breeding time will be required. In this case, when a male and female (one pair) are identified that carry the mutation, they and their offspring will be shipped. Delivery time for strains requiring progeny testing often exceeds 25 weeks and may take 12 months or more due to the difficulties in breeding some strains. The progeny testing cost is in addition to the recovery cost and is based on the number of boxes used and the time taken to produce the mice identified as carrying the mutation. Please note that identified pairs may not reflect the mating scheme utilized by The Jackson Laboratory prior to cryopreservation of the strain. Mating schemes are sometimes modified for successful cryopreservation. Please contact Customer Service for more information on the cost of progeny testing for a strain: Tel: 1-800-422-6423 or 1-207-288-5845. Cryorecovery to establish a Dedicated Supply for greater quantities of mice |
| Licensing | See General Terms and Conditions below |
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