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Strain Name:

NFS.Cg-Hm/J

Stock Number:

002338

Availability:

Repository-Cryopreserved

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General Terms and Conditions

Former Name      NFS.HM    (Changed: 15-DEC-04 )
Genes & Alleles   Hm;

Product Information

Strain Details

Type JAX® GEMM® Strain - Congenic
Additional information on JAX® GEMM® Strains.
Type JAX® GEMM® Strain - Mutant Strain
Specieslaboratory mouse
GenerationF?+2p (08-JAN-04)
Mammalian Phenotype Terms assigned by genotype

The following phenotype information may relate to a genetic background differing from this JAX® Mice strain.

Hm/Hm

        C3Fe.Cg-Hm
  • limbs/digits/tail phenotype
  • abnormal phalanx morphology (MGI Ref ID J:13425)
    • detectable by E14.5
  • interdigital webbing (MGI Ref ID J:68687)
    • complete webbing with normal tibia
    • webbing between digits 2,3,4, and 5 extends to the nails in the hindfeet; to the base of the distal phalanx in the forefeet
    • webbing is extensive and prevents toe elongation, resulting in severe flexion at birth
  • skeleton phenotype
  • abnormal phalanx morphology (MGI Ref ID J:13425)
    • detectable by E14.5

Hm/Hm+

        C3Fe.Cg-Hm
  • limbs/digits/tail phenotype
  • abnormal phalanx morphology (MGI Ref ID J:13425)
    • on all four feet, the second phalanx of digits 2,3,4,and 5 is strongly flexed
    • detectable by E15
  • interdigital webbing (MGI Ref ID J:68687)
    • partial webbing
    • webbing prevents toe elongation, resulting in flexion at birth
  • skeleton phenotype
  • abnormal phalanx morphology (MGI Ref ID J:13425)
    • on all four feet, the second phalanx of digits 2,3,4,and 5 is strongly flexed
    • detectable by E15

Gene & Allele Details

Allele Symbol Hm
Allele Name hammertoe

Related Strains

Strains carrying   Hm allele
000291   C3FeLe.Cg-a/a Hm KitlSl Krt71Ca-J/J
View Strains carrying   Hm     (1 strain)

Additional Web Information

Congenic Nomenclature

Research Applications

This mouse can be used to support research in many areas including:

Hm related

Developmental Biology Research
Skeletal Defects

References

Additional References

Price and Supply Information

Strain Name: NFS.Cg-Hm/J
Stock Number: 002338

Price Details

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Supply Details

Standard SupplyRepository-Cryopreserved. Must Be Recovered. Please refer to pricing and supply notes for further information.
Supply Notes Cryorecovery - Standard.
The recovery process begins when a signed agreement form is returned to the Customer Service Department after order placement. Although results vary by strain, at least two males and two females (two pairs) will be provided, typically within 15 weeks of our receipt of the signed agreement form. If the first recovery attempt is unsuccessful or only one pair is recovered, a second recovery will be done, extending the delivery time to approximately 25 weeks. At least one member of each pair will be of known genotype and will carry the mutation if it is a mutant strain. Please note that pairs may not reflect the mating scheme utilized by The Jackson Laboratory prior to cryopreservation of the strain. Mating schemes are sometimes modified for successful cryopreservation. Price represents a repository maintenance fee, which includes the cost of recovery of the strain from the cryopreservation resource and the periodic replacement of the frozen embryos used for recovery.

Cryorecovery to establish a Dedicated Supply for greater quantities of mice.
One to two pairs will be recovered to establish a Dedicated Supply of mice. Price by quotation. For more information on Dedicated Supply, please contact JAX® Services: Tel: 1-800-422-6423 or 1-207-288-5845; Email: jaxservices@jax.org.

LicensingSee General Terms and Conditions below  

General Terms and Conditions

View JAX® Mice & Services Conditions of Use.

The Jackson Laboratory's Genotype Promise

The Jackson Laboratory has rigorous genetic quality control and mutant gene genotyping programs to ensure the genetic background of JAX® Mice strains as well as the genotypes of strains with identified molecular mutations. JAX® Mice strains are only made available to researchers after meeting our standards. However, the phenotype of each strain may not be fully characterized and/or captured in the strain data sheets. Therefore, we cannot guarantee a strain's phenotype will meet all expectations. To ensure that JAX® Mice will meet the needs of individual research projects or when requesting a strain that is new to your research, we suggest ordering and performing tests on a small number of mice to determine suitability for your particular project.
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Contact Information
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Fax: 207.288.6150
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