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- Description
- Phenotype
- Genes & alleles
- Genotyping
- Health & husbandry
- References
- Purchasing information
- Terms of Use
Description
Strain Information
Former Names STOCK TgN(Zfy1lacZ)218Bri (Changed: 15-DEC-04 ) Type Mutant Stock; Transgenic; Additional information on Genetically Engineered Mutant Mice. Species laboratory mouse Description
LacZ staining is present in the embryonic gonad of both male and female mice (somatic cells, but not germ cells). Staining is less intense in males and is repressed shortly after formation of the testis cords. Staining is also present in the kidney, brain, and spine prior to birth.Development
Transgene construct contains a 5' genomic fragment plus -4.3 kb of mouse Zfy1.
Control Information
| Control | ||
|---|---|---|
| None Available | ||
| Considerations for Choosing Controls | ||
Related Strains
lacZ Expression Strains
View lacZ Expression Strains (175 strains)
Additional Web Information
Fluorescent Proteins/lacZ Systems
Phenotype
Phenotype Information
assigned by genotype
The following phenotype information may relate to a genetic background differing from this JAX® Mice strain.
Tg(Zfy1-lacZ)218Bri/Tg(Zfy1-lacZ)218Bri
involves: C57BL/6 * SJL
- normal phenotype
- no abnormal phenotype detected (MGI Ref ID J:18918)
- homozygous mice are viable and fertile
This mouse can be used to support research in many areas including:
Research Tools
lacZ Expression
Genetics Research (Tissue/Cell Markers: testicular cell marker)
Reproductive Biology Research (testicular cell marker)
Genes & Alleles
Gene & Allele Information
| Allele Symbol | Tg(Zfy1-lacZ)218Bri | ||
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| Allele Name | transgene insertion 218, Ralph L Brinster | ||
| Allele Type | Transgenic (Reporter) | ||
| Common Name(s) | Tgn(ZFY1lacZ)218Brin; line 4592; | ||
| Site of Expression | lacZ expression is detected in the embryonic gonad of male and female mice (somatic, but not germ cells), expression is repressed in males shortly after the formation of the testis cords. Expression is also detected in the kidney, brain and spine prior to birth. | ||
| Promoter | Zfy1, zinc finger protein 1, Y linked, mouse, laboratory | ||
| Molecular Note | The transgene construct contains a 5' genomic fragment of Zfy1, plus ~4.3 kb of mouse Zfy1 with the LacZ sequence fused to exon1b. [MGI Ref ID J:18918] | ||
Genotyping
Genotyping Information
This strain will not have a genotyping protocol or one is not currently available.
Helpful Links
Optimizing PCR Protocols
References
References
Selected Reference(s)
Zambrowicz BP; Zimmermann JW; Harendza CJ; Simpson EM; Page DC; Brinster RL; Palmiter RD. 1994. Expression of a mouse Zfy-1/lacZ transgene in the somatic cells of the embryonic gonad and germ cells of the adult testis. Development 120(6):1549-59. [PubMed: 8050362] [MGI Ref ID J:18918]
Health & husbandry
Health & Colony Maintenance Information
Currently there no information available for this strain. This may be due to the supply level of this strain.
Purchasing information
Pricing, Supply Level & Notes, Controls, General Terms & Conditions
Pricing
| Pricing for USA, Canada and Mexico shipping destinations |
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*Price(s) in US dollars ($)
Weeks of Age Price* Gender Cryorecovery Fee $1900.00
Additional Supply Details
| Pricing for International shipping destinations |
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*Price(s) in US dollars ($)
Weeks of Age Price* Gender Cryorecovery Fee $2470.00
Additional Supply Details
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Supply Details
| Standard Supply | Repository-Cryopreserved. Must Be Recovered. Please refer to pricing and supply notes for further information. |
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| Supply Notes |
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Control Information
| Control | ||
|---|---|---|
| None Available | ||
| Considerations for Choosing Controls | ||
| USA, Canada and Mexico - Control Pricing Information for Genetically Engineered Mutant Strains. | ||
| International - Control Pricing Information for Genetically Engineered Mutant Strains. | ||
General Terms and Conditions
See Terms of Use
The Jackson Laboratory's Genotype Promise
The Jackson Laboratory has rigorous genetic quality control and mutant gene genotyping programs to ensure the genetic background of JAX® Mice strains as well as the genotypes of strains with identified molecular mutations. JAX® Mice strains are only made available to researchers after meeting our standards. However, the phenotype of each strain may not be fully characterized and/or captured in the strain data sheets. Therefore, we cannot guarantee a strain's phenotype will meet all expectations. To ensure that JAX® Mice will meet the needs of individual research projects or when requesting a strain that is new to your research, we suggest ordering and performing tests on a small number of mice to determine suitability for your particular project.Ordering and Purchasing Information
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| phone: | 207-288-6470 |
| fax: | 207-288-6655 |
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