Strain Name: |
B6.Cg-KitlSl-18H/EiJ |
|---|---|
Stock Number: |
002993 |
Availability: | Repository-Cryopreserved |
Price and Supply Information | |
General Terms and Conditions |
| Former Name |
C57BL/6JEi-KitlSl-18H (Changed: 08-APR-08
) |
| Genes & Alleles | Kitl; KitlSl-18H; |
Product Information
Strain Details
Type JAX® GEMM® Strain - Congenic Additional information on JAX® GEMM® Strains. Type JAX® GEMM® Strain - Radiation Induced Mutation Species laboratory mouse Generation N10 Strain Development
The steel 18 Harwell mutation, then on a mixed C3H and 101 background, was imported in 1988 from Harwell into NCI, Frederick. There, Peter Donovan maintained it by backrossing to C3H/HeN and C3H/HeJ. In 1993 this mutation was imported from NCI to the laboratory of Eva Eicher at The Jackson Laboratory and the estimated backcross generation at that time was greater than N10. The Eicher laboratory then backcrossed this mutation onto a B6 background using both C57BL/6JEi and C57BL/6J.
Mammalian Phenotype Terms assigned by genotype |
Gene & Allele Details
| Allele Symbol | KitlSl-18H | ||
|---|---|---|---|
| Allele Name | steel 18 Harwell | ||
| Gene Symbol and Name | Kitl, kit ligand | ||
| Chromosome | 10 | ||
| Gene Common Name(s) | Clo; Con; DKFZp686F2250; Gb; KL-1; Kl1; Kl2; MGF; Mgf; SCF; SF; SHEP7; SLF; Sl; Steel; Steel factor; cloud gray; contrasted; grizzle-belly; mast cell growth factor; steel; stem cell factor; | ||
Related Strains
Strains carrying other alleles of Kitl
000090 129S1/Sv-Oca2+ Tyr+ KitlSl-J/J 000124 B6.Cg-KitlSl Krt71Ca/J 000160 B6.D2-KitlSl-d/J 000291 C3FeLe.Cg-a/a Hm KitlSl Krt71Ca-J/J 001380 C3Sn.Cg-KitlSl-con/J 003252 C57BL/6J-KitlSl-20J/J 006839 C57BL/6J-KitlSl-22J/J 000979 STOCK KitlSl-16J/J 000161 WB.D2-KitlSl-d/J 000693 WC/ReJ KitlSl/J 100401 WCB6F1/J KitlSl KitlSl-d View Strains carrying other alleles of Kitl (11 strains)
Additional Web Information
Congenic Nomenclature
Research Applications
This mouse can be used to support research in many areas including:
KitlSl-18H relatedDevelopmental Biology Research
Internal/Organ Defects (urogenital)
Reproductive Biology Research
Cancer Research
Growth Factors/Receptors/Cytokines
Dermatology Research
Color and White Spotting Defects
Developmental Biology Research
Embryonic Lethality (Homozygous)
Perinatal Lethality
Postnatal Mortality
Hematological Research
Immunology and Inflammation Research
Growth Factors/Receptors/Cytokines
References
Selected Reference(s)
Additional ReferencesCattanach BM; Rasberry C. 1988. A new steel allele with early post-implantation homozygous lethality Mouse News Lett 80:157-58. [MGI Ref ID J:18280]
Price and Supply Information
| Strain Name: | B6.Cg-KitlSl-18H/EiJ |
| Stock Number: | 002993 |
Price Details
IMPORTANT NOTE: Prices are based on shipping destination. The shipping destinations are:
- USA, Canada and Mexico
- International
*Pricing for Shipping Destination selected:
International
| Price(s) in US dollars ($) | |||||
|---|---|---|---|---|---|
| Cryorecovery Fee | $2470.00 | ||||
Supply Details
| Standard Supply | Repository-Cryopreserved. Must Be Recovered. Please refer to pricing and supply notes for further information. |
|---|---|
| Supply Notes |
Cryorecovery of Strains Needing Progeny Testing. The recovery process begins when a signed agreement form is returned to the Customer Service Department after order placement. Although results vary by strain, at least two untested males and two untested females (two pairs) will be recovered, typically within 15 weeks of our receipt of the signed agreement form. If the first recovery attempt is unsuccessful or only one pair is recovered, a second recovery will be done, extending the overall recovery time to approximately 25 weeks. However, all pups recovered will be sent. Progeny testing is required to identify the genotype of mice of this strain, as a genotyping assay is not available. This type of testing involves breeding the recovered animals and assessing the phenotype of the offspring in order to identify animals carrying the mutation of interest. We can perform the progeny testing for you as a service or we can ship all recovered animals (at least two untested pairs) to you for progeny testing at your facility. If you perform the progeny testing, there is NO guarantee that a carrier will be identified. If we perform progeny testing as a service, additional breeding time will be required. In this case, when a male and female (one pair) are identified that carry the mutation, they and their offspring will be shipped. Delivery time for strains requiring progeny testing often exceeds 25 weeks and may take 12 months or more due to the difficulties in breeding some strains. The progeny testing cost is in addition to the recovery cost and is based on the number of boxes used and the time taken to produce the mice identified as carrying the mutation. Please note that identified pairs may not reflect the mating scheme utilized by The Jackson Laboratory prior to cryopreservation of the strain. Mating schemes are sometimes modified for successful cryopreservation. Please contact Customer Service for more information on the cost of progeny testing for a strain: Tel: 1-800-422-6423 or 1-207-288-5845. Cryorecovery to establish a Dedicated Supply for greater quantities of mice |
| Licensing | See General Terms and Conditions below |
General Terms and Conditions
View JAX® Mice & Services Conditions of Use.
The Jackson Laboratory's Genotype Promise
The Jackson Laboratory has rigorous genetic quality control and mutant gene genotyping programs to ensure the genetic background of JAX® Mice strains as well as the genotypes of strains with identified molecular mutations. JAX® Mice strains are only made available to researchers after meeting our standards. However, the phenotype of each strain may not be fully characterized and/or captured in the strain data sheets. Therefore, we cannot guarantee a strain's phenotype will meet all expectations. To ensure that JAX® Mice will meet the needs of individual research projects or when requesting a strain that is new to your research, we suggest ordering and performing tests on a small number of mice to determine suitability for your particular project.Ordering and Purchasing Information
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