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Strain Name:

STOCK Rb(16.17)7Bnr-Myo15sh2-2J/J

Stock Number:

003304

Availability:

Repository-Cryopreserved


Price and Supply Information

General Terms and Conditions

Former Name      Rb7Bnr    (Changed: 15-DEC-04 )
      STOCK Rb7Bnr-Myo15sh2-2J    (Changed: 15-DEC-04 )
Genes & Alleles   Myo15;   Myo15sh2-2J;   Rb(16.17)7Bnr;   ;


Product Information

Strain Details

Type Chromosome Aberration
Additional information on Mice with Chromosomal Aberrations.
Type JAX® GEMM® Strain - Mutant Stock
Additional information on JAX® GEMM® Strains.
Type Robertsonian
Additional information on Mice with Chromosomal Aberrations.
Specieslaboratory mouse
GenerationN1
Related Disease (OMIM) Terms

Deafness, Neurosensory, Autosomal Recessive 3; DFNB3
Mammalian Phenotype Terms assigned by genotype

Myo15sh2-2J/Myo15sh2-2J

        involves: STOCK Rb(16.17)7Bnr
  • behavior/neurological phenotype
  • circling (MGI Ref ID J:69998)
  • hearing/vestibular/ear phenotype
  • circling (MGI Ref ID J:69998)
  • deafness (MGI Ref ID J:69998)

Gene & Allele Details

Allele Symbol Myo15sh2-2J
Allele Name shaker 2, 2 Jackson
Strain of OriginSTOCK Rb(16.17)7Bnr
Gene Symbol and Name Myo15, myosin XV
Chromosome 11
Gene Common Name(s) DFNB3; DKFZp686N18198; FLJ17274; FLJ31311; RGD1561873; sh-2; sh2; shaker 2;
Gene Symbol and Name Rb(16.17)7Bnr, Robertsonian translocation, Chr 16 and 17, Universitat Bonn/Rhein 7
Chromosome 16
Gene Common Name(s) Rb7Bnr;

Colony Maintenance

Breeding & HusbandryThis strain produces small litters due to the chromosomal aberration, but they are very consistant and reliable breeders.

Related Strains

Robertsonian Chromosome
001099   AEJ/GnRk-Rb(11.14)1Dn/J
002545   B6 x RBA/DnJ
000610   B6 x STOCK Rb(6.15)1Ald/J
000861   B6.Cg-Rb(1.3)1Lub/J
000952   B6.Cg-Rb(10.11)8Bnr/J
000960   B6.Cg-Rb(2.8)2Lub/J
001733   B6.WMP-Rb(10.17)9Mpl/J
001734   B6.WMP-Rb(13.15)10Mpl/J
001727   B6.WMP-Rb(2.16)3Mpl/J
001728   B6.WMP-Rb(3.12)4Mpl/J
001729   B6.WMP-Rb(4.6)5Mpl/J
001732   B6.WMP-Rb(8.9)8Mpl/J
001796   B6Ei.Cg-Rb(1.2)18Lub/J
001921   B6Ei.Cg-Rb(1.7)1Rma/J
001386   B6Ei.Cg-Rb(10.12)5Lub/J
001617   B6Ei.Cg-Rb(10.15)23Lub/J
001795   B6Ei.Cg-Rb(11.13)4Bnr/J
000150   B6Ei.Cg-Rb(11.16)2H/J
000906   B6Ei.Cg-Rb(16.17)8Lub-tw3Lub/+ +/J
001387   B6Ei.Cg-Rb(2.17)11Rma/J
001613   B6Ei.Cg-Rb(5.14)21Lub/J
001616   B6Ei.Cg-Rb(5.15)4Lub/J
001791   B6Ei.Cg-Rb(5.19)1Wh/J
000762   B6Ei.Cg-Rb(6.15)1Ald/J
001798   B6Ei.Cg-Rb(6.16)24Lub/J
001389   B6Ei.Cg-Rb(6.7)13Rma/J
001615   B6Ei.Cg-Rb(7.18)9Lub/J
001797   B6Ei.Cg-Rb(8.12)22Lub/J
000888   B6Ei.Cg-Rb(8.14)16Rma/J
001792   B6Ei.Cg-Rb(9.19)163H/J
001794   B6Ei.WMP-Rb(13.16)1Mpl/J
002470   B6EiC3Sn x B6-Rb(5.8)3Dn/J
004850   B6EiC3Sn-Rb(12.T171665Dn)2Cje/CjeDn
000975   C57BL/6J x STOCK Rb(1.3)1Ei/J
001391   C57BL/6J-Rb(4.15)1Rk/J
001390   C57BL/6J-Rb(6.18)2Dn/J
001793   C57BL/6JEi-Rb(X.2)2Ad/J
000714   CByJ.RBF-Rb(8.12)5Bnr
001802   CByJ.RBF-Rb(8.12)5Bnr/J
000874   RBA/DnJ
000609   RBB/DnJ
000889   RBC/DnJ
000860   STOCK Rb(1.2)18Lub/J
000862   STOCK Rb(1.7)1Rma/J
000891   STOCK Rb(10.11)5Rma/J
000614   STOCK Rb(10.11)8Bnr/J
000892   STOCK Rb(10.12)5Lub/J
000729   STOCK Rb(11.13)4Bnr/J
000895   STOCK Rb(11.13)6Lub/J
001100   STOCK Rb(13.16)1Mpl/J
000615   STOCK Rb(16.17)7Bnr
000898   STOCK Rb(16.17)8Lub/J
000865   STOCK Rb(2.17)11Rma/J
000867   STOCK Rb(2.18)6Rma/J
000871   STOCK Rb(3.15)2Rk/J
000980   STOCK Rb(3.8)2Ei/J
000869   STOCK Rb(3.8)2Rma/J
000870   STOCK Rb(3.9)12Lub/J
000873   STOCK Rb(4.11)12Rma/J
000876   STOCK Rb(4.15)4Rma/J
000720   STOCK Rb(4.6)2Bnr/J
000878   STOCK Rb(5.14)21Lub/J
000880   STOCK Rb(5.15)15Rma/J
000881   STOCK Rb(5.17)7Rma/J
000882   STOCK Rb(5.19)1Wh/J
001884   STOCK Rb(5.6)1Ty/J
000885   STOCK Rb(6.16)24Lub
000887   STOCK Rb(8.12)22Lub/J
000613   STOCK Rb(9.19)163H/J
View Robertsonian Chromosome     (69 strains)

Research Applications

This mouse can be used to support research in many areas including:

Myo15sh2-2J related

Mouse/Human Gene Homologs
deafness, neurosensory, autosomal recessive, 3

Neurobiology Research
Tremor Defects
Vestibular and Hearing Defects

Sensorineural Research
Vestibular and Hearing Defects

References

Additional References

Price and Supply Information

Strain Name: STOCK Rb(16.17)7Bnr-Myo15sh2-2J/J
Stock Number: 003304

Price Details

IMPORTANT NOTE: Prices are based on shipping destination. The shipping destinations are:

*Pricing for Shipping Destination selected:

        USA, Canada and Mexico

Price(s) in US dollars ($)
Cryorecovery Fee $1900.00

Supply Details

Standard SupplyRepository-Cryopreserved. Must Be Recovered. Please refer to pricing and supply notes for further information.
Supply Notes Cryorecovery of Strains Needing Progeny Testing.
The recovery process begins when a signed agreement form is returned to the Customer Service Department after order placement. Although results vary by strain, at least two untested males and two untested females (two pairs) will be recovered, typically within 15 weeks of our receipt of the signed agreement form. If the first recovery attempt is unsuccessful or only one pair is recovered, a second recovery will be done, extending the overall recovery time to approximately 25 weeks. However, all pups recovered will be sent.

Progeny testing is required to identify the genotype of mice of this strain, as a genotyping assay is not available. This type of testing involves breeding the recovered animals and assessing the phenotype of the offspring in order to identify animals carrying the mutation of interest. We can perform the progeny testing for you as a service or we can ship all recovered animals (at least two untested pairs) to you for progeny testing at your facility. If you perform the progeny testing, there is NO guarantee that a carrier will be identified. If we perform progeny testing as a service, additional breeding time will be required. In this case, when a male and female (one pair) are identified that carry the mutation, they and their offspring will be shipped. Delivery time for strains requiring progeny testing often exceeds 25 weeks and may take 12 months or more due to the difficulties in breeding some strains. The progeny testing cost is in addition to the recovery cost and is based on the number of boxes used and the time taken to produce the mice identified as carrying the mutation. Please note that identified pairs may not reflect the mating scheme utilized by The Jackson Laboratory prior to cryopreservation of the strain. Mating schemes are sometimes modified for successful cryopreservation. Please contact Customer Service for more information on the cost of progeny testing for a strain: Tel: 1-800-422-6423 or 1-207-288-5845.

Cryorecovery to establish a Dedicated Supply for greater quantities of mice
One to two pairs will be recovered to establish a Dedicated Supply of mice. Price by quotation. For more information on Dedicated Supply, please contact JAX® Services, Tel: 1-800-422-6423 or 1-207-288-5845.
Genomic DNA is available for this strain from the Mouse DNA Resource.

LicensingSee General Terms and Conditions below  

General Terms and Conditions

View JAX® Mice & Services Conditions of Use.

The Jackson Laboratory's Genotype Promise

The Jackson Laboratory has rigorous genetic quality control and mutant gene genotyping programs to ensure the genetic background of JAX® Mice strains as well as the genotypes of strains with identified molecular mutations. JAX® Mice strains are only made available to researchers after meeting our standards. However, the phenotype of each strain may not be fully characterized and/or captured in the strain data sheets. Therefore, we cannot guarantee a strain's phenotype will meet all expectations. To ensure that JAX® Mice will meet the needs of individual research projects or when requesting a strain that is new to your research, we suggest ordering and performing tests on a small number of mice to determine suitability for your particular project.
Ordering and Purchasing Information

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Contact Information
Orders & Technical Support
Tel: 800.422.6423 or 207.288.5845
Fax: 207.288.6150
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