Strain Name:

FVB/N-Tg(Zp3-cre)3Mrt/J

Stock Number:

003377

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Availability:

Cryopreserved - Ready for recovery

Description

The genotypes of the animals provided may not reflect those discussed in the strain description or the mating scheme utilized by The Jackson Laboratory prior to cryopreservation. Please inquire for possible genotypes for this specific strain.

Strain Information

Former Names FVB/N-TgN(Zp3-Cre)3Mrt    (Changed: 15-DEC-04 )
Type Mutant Strain; Transgenic;
Additional information on Genetically Engineered and Mutant Mice.
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Specieslaboratory mouse
 
Donating InvestigatorDr. Gail Martin,   University of California San Francisco

Description
The strain originated on an FVB/N background and is currently on the same background. The investigator maintains the strain by breeding hemizygotes. Homozygotes are subfertile. This is a transgenic line in which cre expression is controlled by the regulatory sequences from the mouse zona pellucida 3 (Zp3) gene, which is normally expressed exclusively in the growing oocyte prior to the completion of the first meiotic division. This strain would be useful for deleting a floxed sequence specifically in the female germ line.

Development
A CreZp3 construct was injected into FVB/N zygotes to produce the founder line. The strain originated on an FVB/N background and is currently on the same background. Female homozygotes are subfertile.

Control Information

  Control
   Noncarrier
   001800 FVB/NJ
 
  Considerations for Choosing Controls

Related Strains

Strains carrying   Tg(Zp3-cre)3Mrt allele
003394   B6.FVB-Tg(Zp3-cre)3Mrt/J
View Strains carrying   Tg(Zp3-cre)3Mrt     (1 strain)

Strains carrying other alleles of Zp3
004038   B6.129S4-Zp3tm1Dean/J
006888   C57BL/6-Tg(Zp3-cre)1Gwh/J
003651   C57BL/6-Tg(Zp3-cre)93Knw/J
003650   C57BL/6J-Tg(Zp3-cre)82Knw/KnwJ
026266   D2.B6-Tg(Zp3-cre)93Knw/SjJ
006129   STOCK Tg(Zp3-EGFP)1Dean/J
View Strains carrying other alleles of Zp3     (6 strains)

Strains carrying other alleles of cre
004337   129(Cg)-Foxg1tm1(cre)Skm/J
008569   129-Alpltm1(cre)Nagy/J
017611   129-Mcm2tm1(cre/ERT2)Scpr/J
005989   129;FVB-Tg(PTH-cre)4167Slib/J
007179   129S.Cg-Tg(UBC-cre/ERT2)1Ejb/J
007915   129S.FVB-Tg(Amh-cre)8815Reb/J
003328   129S/Sv-Tg(Prm-cre)58Og/J
026200   129S1.Cg-Tg(Vsx2-cre)2690Chow/J
004302   129S1/Sv-Hprttm1(cre)Mnn/J
022137   129S4.Cg-Tg(Wnt1-cre)2Sor/J
003960   129S6-Tg(Prnp-GFP/cre)1Blw/J
008523   129S6.Cg-Tg(NPHS2-cre)295Lbh/BroJ
009575   B6(129S4)-Et(cre/ERT2)119Rdav/J
009580   B6(129S4)-Et(cre/ERT2)1382Rdav/J
012688   B6(129S4)-Et(cre/ERT2)13866Rdav/J
009581   B6(129S4)-Et(cre/ERT2)1642Rdav/J
009582   B6(129S4)-Et(cre/ERT2)1645Rdav/J
009583   B6(129S4)-Et(cre/ERT2)1957Rdav/J
009584   B6(129S4)-Et(cre/ERT2)2007Rdav/J
009585   B6(129S4)-Et(cre/ERT2)2047Rdav/J
009574   B6(129S4)-Et(cre/ERT2)21Rdav/J
009577   B6(129S4)-Et(cre/ERT2)296Rdav/J
009578   B6(129S4)-Et(cre/ERT2)398Rdav/J
009573   B6(129S4)-Et(cre/ERT2)4Rdav/J
010688   B6(129S4)-Et(cre/ERT2)6691Rdav/J
010689   B6(129S4)-Et(cre/ERT2)6959Rdav/J
010690   B6(129S4)-Et(cre/ERT2)7089Rdav/J
010691   B6(129S4)-Et(cre/ERT2)7149Rdav/J
010692   B6(129S4)-Et(cre/ERT2)7381Rdav/J
010693   B6(129S4)-Et(cre/ERT2)8120Rdav/J
010694   B6(129S4)-Et(cre/ERT2)8131Rdav/J
009579   B6(129S4)-Et(cre/ERT2)837Rdav/J
010695   B6(129S4)-Et(cre/ERT2)9699Rdav/J
009587   B6(129S4)-Et(icre)1402Rdav/J
009588   B6(129S4)-Et(icre)1470Rdav/J
009589   B6(129S4)-Et(icre)1555Rdav/J
009586   B6(129S4)-Et(icre)754Rdav/J
010696   B6(129S4)-Et(icre/ERT2)10596Rdav/J
010697   B6(129S4)-Et(icre/ERT2)10727Rdav/J
012689   B6(129S4)-Et(icre/ERT2)14163Rdav/J
012690   B6(129S4)-Et(icre/ERT2)14208Rdav/J
012694   B6(129S4)-Et(icre/ERT2)14915Rdav/J
012687   B6(129S4)-Tg(SYN1-icre/mRFP1)9934Rdav/J
022356   B6(129X1)-Tg(Cd4-cre/ERT2)11Gnri/J
010774   B6(Cg)-Calb2tm1(cre)Zjh/J
013730   B6(Cg)-Calb2tm2.1(cre/ERT2)Zjh/J
017562   B6(Cg)-Cd8atm1.1(cre)Koni/J
012704   B6(Cg)-Crhtm1(cre)Zjh/J
010705   B6(Cg)-Dlx5tm1(cre/ERT2)Zjh/J
013048   B6(Cg)-Etv1tm1.1(cre/ERT2)Zjh/J
018448   B6(Cg)-Foxn1tm3(cre)Nrm/J
010776   B6(Cg)-Lhx6tm1(cre/ERT2)Zjh/J
010777   B6(Cg)-Pvalbtm1(cre/ERT2)Zjh/J
010708   B6(Cg)-Ssttm1(cre/ERT2)Zjh/J
016223   B6(Cg)-Tg(Phox2b-cre)3Jke/J
016829   B6(SJL)-Pou5f1tm1.1(cre/Esr1*)Yseg/J
021881   B6.129(Cg)-Arctm1.1(cre/ERT2)Luo/J
018867   B6.129(Cg)-Axin2tm1(cre/ERT2)Rnu/J
021882   B6.129(Cg)-Fostm1.1(cre/ERT2)Luo/J
016959   B6.129(Cg)-Foxp3tm4(YFP/cre)Ayr/J
023055   B6.129(Cg)-Krt12tm3(cre)Wwk/J
008463   B6.129-Gt(ROSA)26Sortm1(cre/ERT2)Tyj/J
008320   B6.129-Leprtm2(cre)Rck/J
017526   B6.129-Nos1tm1(cre)Mgmj/J
005697   B6.129-Otx1tm4(cre)Asim/J
018938   B6.129-Tac2tm1.1(cre)Qima/J
017769   B6.129-Trpv1tm1(cre)Bbm/J
004146   B6.129-Tg(Pcp2-cre)2Mpin/J
008710   B6.129P2(129S4)-Hprttm10(Ple162-EGFP/cre)Ems/Mmjax
008877   B6.129P2(129S4)-Hprttm12(Ple177-EGFP/cre)Ems/Mmjax
009116   B6.129P2(129S4)-Hprttm16(Ple167-EGFP/cre)Ems/Mmjax
008709   B6.129P2(129S4)-Hprttm9(Ple178-EGFP/cre)Ems/Mmjax
006785   B6.129P2(C)-Cd19tm1(cre)Cgn/J
021160   B6.129P2(Cg)-Cx3cr1tm2.1(cre/ERT)Litt/WganJ
006084   B6.129P2(Cg)-Foxg1tm1(cre)Skm/J
010611   B6.129P2(Cg)-Ighg1tm1(IRES-cre)Cgn/J
007770   B6.129P2-Aicdatm1(cre)Mnz/J
008875   B6.129P2-Lgr5tm1(cre/ERT2)Cle/J
016934   B6.129P2-Lgr6tm2.1(cre/ERT2)Cle/J
004781   B6.129P2-Lyz2tm1(cre)Ifo/J
017320   B6.129P2-Pvalbtm1(cre)Arbr/J
016222   B6.129S(Cg)-Id2tm1.1(cre/ERT2)Blh/ZhuJ
017915   B6.129S(Cg)-Pgrtm1.1(cre)Shah/AndJ
013594   B6.129S-Atoh1tm5.1(Cre/PGR)Hzo/J
021794   B6.129S1(Cg)-Ascl3tm1.1(EGFP/cre)Ovi/J
024637   B6.129S1(SJL)-Nkx2-5tm2(cre)Rph/J
006600   B6.129S1-Mnx1tm4(cre)Tmj/J
005628   B6.129S2-Emx1tm1(cre)Krj/J
022510   B6.129S4-Gpr88tm1.1(cre/GFP)Rpa/J
017578   B6.129S4-Mcpt8tm1(cre)Lky/J
003755   B6.129S4-Meox2tm1(cre)Sor/J
007893   B6.129S4-Myf5tm3(cre)Sor/J
005623   B6.129S6-Shhtm2(cre/ERT2)Cjt/J
006878   B6.129S6-Taglntm2(cre)Yec/J
012839   B6.129X1(Cg)-Tnfrsf4tm2(cre)Nik/J
008712   B6.129X1-Twist2tm1.1(cre)Dor/J
006054   B6.C-Tg(CMV-cre)1Cgn/J
020811   B6.C-Tg(Pgk1-cre)1Lni/CrsJ
019148   B6.Cg-Acantm1(cre/ERT2)Crm/J
023530   B6.Cg-Avptm1.1(cre)Hze/J
013590   B6.Cg-Braftm1Mmcm Ptentm1Hwu Tg(Tyr-cre/ERT2)13Bos/BosJ
023531   B6.Cg-Calb1tm1.1(folA/EGFP/cre)Hze/J
006230   B6.Cg-Cebpatm1Dgt Tg(Mx1-cre)1Cgn/J
012360   B6.Cg-Erbb4tm1.1(cre/ERT2)Aibs/J
023676   B6.Cg-Hprttm331(Ple275-icre/ERT2)Ems/Mmjax
023678   B6.Cg-Hprttm333(Ple281-icre/ERT2)Ems/Mmjax
023679   B6.Cg-Hprttm334(Ple279-icre/ERT2)Ems/Mmjax
023680   B6.Cg-Hprttm335(Ple277-icre/ERT2)Ems/Mmjax
023685   B6.Cg-Hprttm340(Ple252-icre/ERT2)Ems/Mmjax
023686   B6.Cg-Hprttm341(Ple273-icre/ERT2)Ems/Mmjax
023688   B6.Cg-Hprttm343(Ple270-icre/ERT2)Ems/Mmjax
022861   B6.Cg-Nxph4tm1.1(cre/ERT2)Hze/J
017763   B6.Cg-Pax7tm1(cre/ERT2)Gaka/J
022862   B6.Cg-Penktm1.1(cre/ERT2)Hze/J
012358   B6.Cg-Pvalbtm1.1(cre)Aibs/J
022863   B6.Cg-Pvalbtm5.1(cre/folA)Hze/J
005622   B6.Cg-Shhtm1(EGFP/cre)Cjt/J
022865   B6.Cg-Trib2tm1.1(cre/ERT2)Hze/J
022762   B6.Cg-Zfp335tm1.2Caw Emx1tm1(cre)Krj/J
017346   B6.Cg-Tg(A930038C07Rik-cre)1Aibs/J
006149   B6.Cg-Tg(ACTA1-cre)79Jme/J
003574   B6.Cg-Tg(Alb-cre)21Mgn/J
006881   B6.Cg-Tg(Aqp2-cre)1Dek/J
011104   B6.Cg-Tg(Atoh1-cre)1Bfri/J
004682   B6.Cg-Tg(CAG-cre/Esr1*)5Amc/J
008520   B6.Cg-Tg(CD2-cre)4Kio/J
009350   B6.Cg-Tg(CDX2-cre)101Erf/J
009352   B6.Cg-Tg(CDX2-cre*)189Erf/J
005359   B6.Cg-Tg(Camk2a-cre)T29-1Stl/J
022071   B6.Cg-Tg(Cd4-cre)1Cwi/BfluJ
012237   B6.Cg-Tg(Cdh16-cre)91Igr/J
016241   B6.Cg-Tg(Col1a1-cre/ERT2)1Crm/J
016237   B6.Cg-Tg(Col1a2-cre/ERT)7Cpd/J
006368   B6.Cg-Tg(Cr2-cre)3Cgn/J
008538   B6.Cg-Tg(Cspg4-cre/Esr1*)BAkik/J
006663   B6.Cg-Tg(Eno2-cre)39Jme/J
005069   B6.Cg-Tg(Fabp4-cre)1Rev/J
012712   B6.Cg-Tg(Fev-cre)1Esd/J
012849   B6.Cg-Tg(GFAP-cre/ERT2)505Fmv/J
012886   B6.Cg-Tg(Gfap-cre)73.12Mvs/J
024098   B6.Cg-Tg(Gfap-cre)77.6Mvs/2J
009642   B6.Cg-Tg(Gh1-cre)1Sac/J
024474   B6.Cg-Tg(Il9-cre)#Stck/J
003573   B6.Cg-Tg(Ins2-cre)25Mgn/J
008068   B6.Cg-Tg(Itgax-cre)1-1Reiz/J
008781   B6.Cg-Tg(Kap-cre)29066/2Sig/J
012837   B6.Cg-Tg(Lck-cre)3779Nik/J
003802   B6.Cg-Tg(Lck-cre)548Jxm/J
006889   B6.Cg-Tg(Lck-cre)I540Jxm/J
009643   B6.Cg-Tg(Lhb-cre)1Sac/J
008330   B6.Cg-Tg(Mc4r-cre)25Rck/J
003556   B6.Cg-Tg(Mx1-cre)1Cgn/J
007742   B6.Cg-Tg(Myh11-cre,-EGFP)2Mik/J
008205   B6.Cg-Tg(NPHS2-cre)295Lbh/J
003771   B6.Cg-Tg(Nes-cre)1Kln/J
010536   B6.Cg-Tg(Pcp2-cre)3555Jdhu/J
005975   B6.Cg-Tg(Plp1-cre/ERT)3Pop/J
008827   B6.Cg-Tg(Prdm1-cre)1Masu/J
005584   B6.Cg-Tg(Prrx1-cre)1Cjt/J
003967   B6.Cg-Tg(Rbp3-cre)528Jxm/J
021614   B6.Cg-Tg(S100A8-cre,-EGFP)1Ilw/J
008454   B6.Cg-Tg(Sox2-cre)1Amc/J
006361   B6.Cg-Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/J
003966   B6.Cg-Tg(Syn1-cre)671Jxm/J
017491   B6.Cg-Tg(Tagln-cre)1Her/J
004128   B6.Cg-Tg(Tek-cre)12Flv/J
008863   B6.Cg-Tg(Tek-cre)1Ywa/J
008601   B6.Cg-Tg(Th-cre)1Tmd/J
007606   B6.Cg-Tg(Thy1-cre/ERT2,-EYFP)AGfng/J
012328   B6.Cg-Tg(Tyr-cre/ERT2)13Bos/J
008085   B6.Cg-Tg(UBC-cre/ERT2)1Ejb/J
008610   B6.Cg-Tg(Vav1-cre)A2Kio/J
004586   B6.Cg-Tg(Vil-cre)997Gum/J
021504   B6.Cg-Tg(Vil1-cre)1000Gum/J
008735   B6.Cg-Tg(Wap-cre)11738Mam/JKnwJ
009614   B6.Cg-Tg(Wfs1-cre/ERT2)2Aibs/J
009107   B6.Cg-Tg(Wnt1-cre)11Rth Tg(Wnt1-GAL4)11Rth/J
006234   B6.Cg-Tg(tetO-cre)1Jaw/J
016832   B6.FVB(129)-Tg(Alb1-cre)1Dlr/J
005657   B6.FVB(129)-Tg(Myh6-cre/Esr1*)1Jmk/J
024688   B6.FVB(129S)-Tg(Pax6-GFP/cre)1Rilm/J
006475   B6.FVB(129S4)-Tg(Ckmm-cre)5Khn/J
006451   B6.FVB(129X1)-Tg(Sim1-cre)1Lowl/J
006333   B6.FVB(Cg)-Tg(Neurog3-cre)C1Able/J
014643   B6.FVB-Tg(CMA1-cre)6Thhe/J
006137   B6.FVB-Tg(Cdh5-cre)7Mlia/J
018980   B6.FVB-Tg(Ddx4-cre)1Dcas/KnwJ
003724   B6.FVB-Tg(EIIa-cre)C5379Lmgd/J
011069   B6.FVB-Tg(Gh1-cre)bKnmn/J
011038   B6.FVB-Tg(Myh6-cre)2182Mds/J
014647   B6.FVB-Tg(Pdx1-cre)6Tuv/J
010714   B6.FVB-Tg(Pomc-cre)1Stl/J
022791   B6.FVB-Tg(Rorc-cre)1Litt/J
017535   B6.FVB-Tg(Slc32a1-cre)2.1Hzo/FrkJ
017490   B6.FVB-Tg(Stra8-cre)1Reb/LguJ
024670   B6.FVB-Tg(Ucp1-cre)1Evdr/J
006660   B6.SJL-Slc6a3tm1.1(cre)Bkmn/J
003552   B6129-Tg(Wap-cre)11738Mam/J
023161   B6129S-Tg(Foxp3-EGFP/cre)1aJbs/J
021961   B6;129-Abcg2tm3.1(cre/ERT2)Bsor/J
010531   B6;129-Bmi1tm1(cre/ERT)Mrc/J
008364   B6;129-Chattm1(cre/ERT)Nat/J
004847   B6;129-Gt(ROSA)26Sortm1(cre/ERT)Nat/J
021025   B6;129-Gt(ROSA)26Sortm1(rtTA*M2)Jae Col1a1tm1(tetO-cre)Haho/J
010557   B6;129-Gt(ROSA)26Sortm3(rtTA,tetO-cre/ERT)Nat/J
010529   B6;129-Myf5tm1(cre)Mrc/J
010528   B6;129-Myf6tm2(cre)Mrc/J
024475   B6;129-Myod1tm1.1(cre/ERT,TVA)Gcg/J
008363   B6;129-Nefltm1(cre/ERT)Nat/J
017525   B6;129-Ntstm1(cre)Mgmj/J
005549   B6;129-Pax3tm1(cre)Joe/J
012476   B6;129-Pax7tm2.1(cre/ERT2)Fan/J
009600   B6;129-Six2tm3(EGFP/cre/ERT2)Amc/J
008532   B6;129-Thtm1(cre/Esr1)Nat/J
008531   B6;129-Vamp2tm1(cre/ERT)Nat/J
017968   B6;129-Tg(Cdh5-cre)1Spe/J
024860   B6;129-Tg(Drd1-cre)120Mxu/Mmjax
010988   B6;129P-Cyp11a1tm1(GFP/cre)Pzg/J
010985   B6;129P-Klf3tm1(cre/ERT2)Pzg/J
008529   B6;129P-Tg(Neurog1-cre/ERT2)1Good/J
015854   B6;129P2-Foxl2tm1(GFP/cre/ERT2)Pzg/J
012601   B6;129P2-Lyve1tm1.1(EGFP/cre)Cys/J
006668   B6;129P2-Omptm4(cre)Mom/MomJ
008069   B6;129P2-Pvalbtm1(cre)Arbr/J
012373   B6;129S-Hoxb1tm1(cre)Og/J
014541   B6;129S-Nos1tm1.1(cre/ERT2)Zjh/J
024234   B6;129S-Oxttm1.1(cre)Dolsn/J
022864   B6;129S-Rasgrf2tm1(cre/folA)Hze/J
023526   B6;129S-Rorbtm1.1(cre)Hze/J
023527   B6;129S-Slc17a7tm1.1(cre)Hze/J
023525   B6;129S-Snap25tm2.1(cre)Hze/J
010987   B6;129S-Sox18tm1(GFP/cre/ERT2)Pzg/J
017593   B6;129S-Sox2tm1(cre/ERT2)Hoch/J
021877   B6;129S-Tac1tm1.1(cre)Hze/J
021878   B6;129S-Tac2tm1.1(cre)Hze/J
017685   B6;129S-Wisp3tm1(cre)Mawa/J
007001   B6;129S-Tg(UBC-cre/ERT2)1Ejb/J
009388   B6;129S1-Osr2tm2(cre)Jian/J
014551   B6;129S4-Dlx1tm1(cre/ERT2)Zjh/J
012463   B6;129S4-Foxd1tm1(GFP/cre)Amc/J
012464   B6;129S4-Foxd1tm2(GFP/cre/ERT2)Amc/J
011105   B6;129S4-Olig1tm1(cre)Rth/J
009576   B6;129S4-Et(cre/ERT2)278Rdav/J
006410   B6;129S6-Chattm2(cre)Lowl/J
024948   B6;129S6-Gdnftm1(cre/ERT2)Cos/J
012362   B6;129S6-Tg(Camk2a-cre/ERT2)1Aibs/J
017495   B6;129S7-Crim1tm1(GFP/cre/ERT2)Pzg/J
014638   B6;129X1-Cldn6tm1(cre/ERT2)Dam/J
009616   B6;C3-Tg(A930038C07Rik-cre)4Aibs/J
012433   B6;C3-Tg(ACTA1-rtTA,tetO-cre)102Monk/J
008844   B6;C3-Tg(Ctgf-cre)2Aibs/J
008839   B6;C3-Tg(Cyp39a1-cre)1Aibs/J
009117   B6;C3-Tg(Cyp39a1-cre)7Aibs/J
008848   B6;C3-Tg(Mybpc1-cre)2Aibs/J
009111   B6;C3-Tg(Scnn1a-cre)1Aibs/J
009112   B6;C3-Tg(Scnn1a-cre)2Aibs/J
009613   B6;C3-Tg(Scnn1a-cre)3Aibs/J
009103   B6;C3-Tg(Wfs1-cre/ERT2)3Aibs/J
025806   B6;CBA-Tg(Gsx2-cre)1Kess/J
025807   B6;CBA-Tg(Sox10-cre)1Wdr/J
024507   B6;CBA-Tg(Tbx21-cre)1Dlc/J
017494   B6;D-Tg(Tshz3-GFP/cre)43Amc/J
024926   B6;D2-Tg(Fshr-cre)1Ldu/J
003466   B6;D2-Tg(Sycp1-cre)4Min/J
014160   B6;DBA-Tg(S100b-EGFP/cre/ERT2)22Amc/J
014159   B6;DBA-Tg(Tmem100-EGFP/cre/ERT2)30Amc/J
015855   B6;DBA-Tg(Upk3a-GFP/cre/ERT2)26Amc/J
010803   B6;FVB-Tg(Adipoq-cre)1Evdr/J
018422   B6;FVB-Tg(Aicda-cre)1Rcas/J
023748   B6;FVB-Tg(Aldh1l1-cre)JD1884Gsat/J
011087   B6;FVB-Tg(Crh-cre)1Kres/J
008533   B6;FVB-Tg(Cspg4-cre)1Akik/J
003734   B6;FVB-Tg(GZMB-cre)1Jcb/J
004426   B6;SJL-Tg(Cga-cre)3Sac/J
003554   B6;SJL-Tg(Col2a1-cre)1Bhr/J
017738   B6;SJL-Tg(Foxl1-cre)1Khk/J
005249   B6;SJL-Tg(Krt1-15-cre/PGR)22Cot/J
007610   B6;SJL-Tg(Thy1-cre/ERT2,-EYFP)VGfng/J
007252   B6Ei.129S4-Tg(Prm-cre)58Og/EiJ
018956   B6N.129P2(B6)-Lyz2tm1(cre)Ifo/J
018958   B6N.129P2-Cd19tm1(cre)Cgn/J
021077   B6N.129S1-Mrgprb4tm3(cre)And/J
018957   B6N.129S6(B6)-Chattm2(cre)Lowl/J
017911   B6N.129S6(Cg)-Esr1tm1.1(cre)And/J
019013   B6N.129S6(Cg)-Gt(ROSA)26Sortm2(EGFP/cre)Alj/J
016225   B6N.129S6(Cg)-Scgb1a1tm1(cre/ERT)Blh/J
018974   B6N.B6-Tg(Nr4a1-EGFP/cre)820Khog/J
019021   B6N.Cg-Ccktm1.1(cre)Zjh/J
019022   B6N.Cg-Gad2tm2(cre)Zjh/J
018973   B6N.Cg-Ssttm2.1(cre)Zjh/J
018961   B6N.Cg-Tg(Alb-cre)21Mgn/J
019102   B6N.Cg-Tg(CAG-cre/Esr1*)5Amc/CjDswJ
018966   B6N.Cg-Tg(Camk2a-cre)T29-1Stl/J
018965   B6N.Cg-Tg(Fabp4-cre)1Rev/J
017310   B6N.Cg-Tg(Hsd17b1-icre/ERT2)3Casa/J
018960   B6N.Cg-Tg(Ins2-cre)25Mgn/J
018967   B6N.Cg-Tg(Itgax-cre)1-1Reiz/J
018964   B6N.Cg-Tg(KRT14-cre)1Amc/J
019103   B6N.Cg-Tg(Nes-cre)1Kln/CjDswJ
014094   B6N.Cg-Tg(Sox2-cre)1Amc/J
018968   B6N.Cg-Tg(Vav1-cre)A2Kio/J
018963   B6N.Cg-Tg(Vil-cre)997Gum/J
018972   B6N.FVB(B6)-Tg(Myh6-cre)2182Mds/J
019099   B6N.FVB-Tg(ACTB-cre)2Mrt/CjDswJ
019509   B6N.FVB-Tg(BGLAP-cre)1Clem/J
023047   B6N.FVB-Tg(Dmp1-cre)1Jqfe/BwdJ
017927   B6N.FVB-Tg(Mpz-cre)26Mes/J
010550   B6N.FVB-Tg(Penk-glc-2-cre/ERT2)2And/J
017743   B6N;129S-Prom1tm1(cre/ERT2)Gilb/J
003465   BALB/c-Tg(CMV-cre)1Cgn/J
012641   BALB/c-Tg(S100a4-cre)1Egn/YunkJ
010612   C.129P2(Cg)-Ighg1tm1(IRES-cre)Cgn/J
017353   C.129S4(B6)-Il13tm1(YFP/cre)Lky/J
017582   C.129S4(B6)-Mcpt8tm1(cre)Lky/J
004126   C.Cg-Cd19tm1(cre)Cgn Ighb/J
005673   C.Cg-Tg(Mx1-cre)1Cgn/J
006244   C.Cg-Tg(tetO-cre)1Jaw/J
009155   C57BL/6-Cldn6tm1(cre)Dkwu/J
017557   C57BL/6-Tg(BEST1-cre)1Jdun/J
016097   C57BL/6-Tg(Car1-cre)5Flt/J
011086   C57BL/6-Tg(Cck-cre)CKres/J
008766   C57BL/6-Tg(Cd8a-cre)1Itan/J
006474   C57BL/6-Tg(Grik4-cre)G32-4Stl/J
008314   C57BL/6-Tg(HBB-cre)12Kpe/J
008870   C57BL/6-Tg(Hspa2-cre)1Eddy/J
016261   C57BL/6-Tg(Nes-cre/ERT2)KEisc/J
012906   C57BL/6-Tg(Nes-cre/Esr1*)1Kuan/J
016617   C57BL/6-Tg(Nr4a1-EGFP/cre)820Khog/J
020287   C57BL/6-Tg(Pbsn-cre/Esr1*)14Abch/J
013148   C57BL/6-Tg(Pdgfra-cre)1Clc/J
008535   C57BL/6-Tg(Pf4-cre)Q3Rsko/J
024034   C57BL/6-Tg(Pmch-cre)1Rck/J
016583   C57BL/6-Tg(Slc6a3-icre/ERT2)2Gloss/J
006888   C57BL/6-Tg(Zp3-cre)1Gwh/J
003651   C57BL/6-Tg(Zp3-cre)93Knw/J
021119   C57BL/6J-Tg(Dlx2-cre,-mCherry)4Grsr/GrsrJ
021423   C57BL/6J-Tg(Dlx2-cre,-mCherry)9Grsr/GrsrJ
007567   C57BL/6J-Tg(Itgax-cre,-EGFP)4097Ach/J
018895   C57BL/6J-Tg(Krt6,-cre,-Cerulean)1Grsr/Grsr
018896   C57BL/6J-Tg(Krt6,-cre,-Cerulean)2Grsr/Grsr
018898   C57BL/6J-Tg(Krt6,-cre,-Cerulean)4Grsr/Grsr
018899   C57BL/6J-Tg(Krt6,-cre,-Cerulean)5Grsr/Grsr
021582   C57BL/6J-Tg(Mchr1-cre)1Emf/J
008661   C57BL/6J-Tg(Nkx2-1-cre)2Sand/J
018754   C57BL/6J-Tg(Tbx22,-cre,-mCherry)1Grsr/GrsrJ
019363   C57BL/6J-Tg(Trp63,-cre,-Cerulean)10Grsr/Grsr
018792   C57BL/6J-Tg(Trp63,-cre,-Cerulean)4Grsr/GrsrJ
003650   C57BL/6J-Tg(Zp3-cre)82Knw/KnwJ
018151   C57BL/6N-Krt17tm1(cre,Cerulean)Murr/GrsrJ
023014   C57BL/6N-Tg(Calcrl,cre)4688Nkza/J
012686   C57BL/6N-Tg(Ppp1r2-cre)4127Nkza/J
016582   C57BL/6N-Tg(Slc32a1-icre/ERT2)3Gloss/J
026266   D2.B6-Tg(Zp3-cre)93Knw/SjJ
024701   D2.Cg-Tg(Plp1-cre/ERT)3Pop/SjJ
016833   FVB(Cg)-Tg(Alb1-cre)1Dlr/J
012929   FVB(Cg)-Tg(Dhh-cre)1Mejr/J
011034   FVB(Cg)-Tg(Ghrhr-cre)3242Lsk/J
023407   FVB-HhatTg(TFAP2A-cre)1Will/J
006405   FVB-Tg(Ckmm-cre)5Khn/J
006774   FVB-Tg(Col2a1-cre/ERT)KA3Smac/J
021024   FVB-Tg(Csf1r-icre)1Jwp/J
006954   FVB-Tg(Ddx4-cre)1Dcas/J
004600   FVB-Tg(GFAP-cre)25Mes/J
011037   FVB-Tg(Myh6-cre)2182Mds/J
006364   FVB-Tg(Nr5a1-cre)2Lowl/J
008537   FVB-Tg(Tek-cre)2352Rwng/J
019382   FVB.Cg-Myh9tm1.1Gac Tg(NPHS2-cre)295Lbh/Mmjax
014140   FVB.Cg-Myod1tm2.1(icre)Glh/J
006139   FVB.Cg-Tg(ACTA1-cre)79Jme/J
017595   FVB.Cg-Tg(CAG-cre/Esr1*)5Amc/J
006297   FVB.Cg-Tg(Eno2-cre)39Jme/J
018394   FVB.Cg-Tg(KRT5-cre/ERT2)2Ipc/JeldJ
008244   FVB.Cg-Tg(tetO-cre)1Jaw/J
003376   FVB/N-Tg(ACTB-cre)2Mrt/J
024384   FVB/N-Tg(AMELX-cre)A1Kul/J
003314   FVB/N-Tg(EIIa-cre)C5379Lmgd/J
017928   FVB/N-Tg(Mpz-cre)26Mes/J
006143   FVB/N-Tg(Thy1-cre)1Vln/J
023325   FVB;B6-Tg(Pbsn-cre)20Fwan/J
019096   NOD.129P2(B6)-Lyz2tm1(cre)Ifo/NadlJ
023806   NOD.129P2(Cg)-Cd19tm1(cre)Cgn/J
013233   NOD.B6-Tg(Itgax-cre,-EGFP)4097Ach/J
013234   NOD.Cg-Tg(Cd4-cre)1Cwi/2AchJ
023972   NOD.Cg-Tg(Ins2-cre/ERT)1Dam/SbwJ
023203   NOD.Cg-Tg(Itgax-cre)1-1Reiz/PesaJ
005732   NOD.Cg-Tg(Lck-cre)548Jxm/AchJ
023973   NOD.Cg-Tg(Neurog3-cre)1Dam/SbwJ
013251   NOD.FVB-Tg(EIIa-cre)C5379Lmgd/J
008694   NOD/ShiLt-Tg(Foxp3-EGFP/cre)1cJbs/J
004986   NOD/ShiLt-Tg(Ins2-cre)3Lt/LtJ
003855   NOD/ShiLt-Tg(Ins2-cre)5Lt/LtJ
004987   NOD/ShiLt-Tg(Ins2-cre)6Lt/LtJ
012899   STOCK Agrptm1(cre)Lowl/J
012882   STOCK Ascl1tm1.1(Cre/ERT2)Jejo/J
012706   STOCK Ccktm1.1(cre)Zjh/J
012710   STOCK Ccktm2.1(cre/ERT2)Zjh/J
010910   STOCK Corttm1(cre)Zjh/J
007916   STOCK En1tm2(cre)Wrst/J
007917   STOCK En1tm7(cre/ESR1)Alj/J
007924   STOCK En2tm4(cre/ERT2)Alj/J
008464   STOCK Foxa2tm2.1(cre/Esr1*)Moon/J
016961   STOCK Foxp3tm9(EGFP/cre/ERT2)Ayr/J
010702   STOCK Gad2tm1(cre/ERT2)Zjh/J
010802   STOCK Gad2tm2(cre)Zjh/J
022135   STOCK Gbx2tm1.1(cre/ERT2)Jyhl/J
007913   STOCK Gli1tm3(cre/ERT2)Alj/J
018903   STOCK Gt(ROSA)26Sortm2(EGFP/cre)Alj/J
024283   STOCK Hcn4tm2.1(cre/ERT2)Sev/J
017606   STOCK Hopxtm2.1(cre/ERT2)Joe/J
008876   STOCK Hprttm11(Ple176-EGFP/cre)Ems/Mmjax
016879   STOCK Il17atm1.1(icre)Stck/J
024242   STOCK Isl1tm1(cre)Sev/J
018976   STOCK Kdrtm1(cre)Sato/J
017701   STOCK Kiss1tm1.1(cre/EGFP)Stei/J
018418   STOCK Lrig1tm1.1(cre/ERT2)Rjc/J
007022   STOCK Mnx1tm4(cre)Tmj Tg(SMN2)89Ahmb Smn1tm1Msd Tg(SMN2*delta7)4299Ahmb/J
004192   STOCK Mttptm2Sgy Ldlrtm1Her Apobtm2Sgy Tg(Mx1-cre)1Cgn/J
023342   STOCK Myf5tm1(cre/Esr1*)Trdo/J
024713   STOCK Myl1tm1(cre)Sjb/J
014180   STOCK Myocdtm1(cre)Jomm/J
014552   STOCK Nkx2-1tm1.1(cre/ERT2)Zjh/J
017536   STOCK Nkx6-2tm1(cre/ERT2)Fsh/J
006953   STOCK Notch1tm3(cre)Rko/J
006677   STOCK Olfr151tm28(cre)Mom/MomJ
011103   STOCK Olig2tm2(TVA,cre)Rth/J
009061   STOCK Osr1tm1(EGFP/cre/ERT2)Amc/J
010530   STOCK Pax7tm1(cre)Mrc/J
017569   STOCK Polr2atm1(cre/ERT2)Bbd E4f1tm1.1Llca/J
017585   STOCK Polr2atm1(cre/ERT2)Bbd/J
022757   STOCK Prg4tm1(GFP/cre/ERT2)Abl/J
019378   STOCK Ptf1atm2(cre/ESR1)Cvw/J
016963   STOCK Slc17a6tm2(cre)Lowl/J
016962   STOCK Slc32a1tm2(cre)Lowl/J
013044   STOCK Ssttm2.1(cre)Zjh/J
012719   STOCK Tgfb3tm1(cre)Vk/J
012620   STOCK Trp53tm1Brd Brca1tm1Aash Tg(LGB-cre)74Acl/J
008813   STOCK Trpa1tm2Kykw Tg(CAG-cre/Esr1*)5Amc/J
010908   STOCK Viptm1(cre)Zjh/J
010911   STOCK Wt1tm1(EGFP/cre)Wtp/J
010912   STOCK Wt1tm2(cre/ERT2)Wtp/J
012691   STOCK Et(icre/ERT2)14374Rdav/J
012692   STOCK Et(icre/ERT2)14602Rdav/J
012693   STOCK Et(icre/ERT2)14624Rdav/J
007684   STOCK Tg(Atoh1-cre/Esr1*)14Fsh/J
008783   STOCK Tg(CAG-cre/Esr1*)5Amc Smn1tm3(SMN2/Smn1)Mrph Tg(SMN2*delta7)4299Ahmb Tg(SMN2)89Ahmb/J
004453   STOCK Tg(CAG-cre/Esr1*)5Amc/J
009615   STOCK Tg(Cartpt-cre)1Aibs/J
017336   STOCK Tg(Cd4-cre)1Cwi/BfluJ
005105   STOCK Tg(Chx10-EGFP/cre,-ALPP)2Clc/J
008861   STOCK Tg(Ela1-Cre/ERT2)1Stof/J
008852   STOCK Tg(En2-cre)22Alj/J
005938   STOCK Tg(Eno2-cre)39Jme/J
022763   STOCK Tg(Eno2-cre/ERT2)1Pohlk/J
011062   STOCK Tg(Gdf9-cre)5092Coo/J
012841   STOCK Tg(Ggt1-cre)M3Egn/J
021207   STOCK Tg(Gnrh1-cre)1Dlc/J
017981   STOCK Tg(Hoxb6-cre)#Mku/J
004692   STOCK Tg(Hoxb7-cre)13Amc/J
014600   STOCK Tg(I12b-cre/ERT2,-ALPP)37Fsh/J
008122   STOCK Tg(Ins2-cre/ERT)1Dam/J
004782   STOCK Tg(KRT14-cre)1Amc/J
005107   STOCK Tg(KRT14-cre/ERT)20Efu/J
008582   STOCK Tg(Kcnc2-Cre)K128Stl/LetJ
023426   STOCK Tg(Kiss1-cre)J2-4Cfe/J
017836   STOCK Tg(LGB-cre)74Acl/J
003551   STOCK Tg(MMTV-cre)1Mam/J
003553   STOCK Tg(MMTV-cre)4Mam/J
002527   STOCK Tg(Mx1-cre)1Cgn/J
009074   STOCK Tg(Myh6-cre)1Jmk/J
005650   STOCK Tg(Myh6-cre/Esr1*)1Jmk/J
009102   STOCK Tg(Nefh-cre)12Kul/J
002858   STOCK Tg(Nes-cre)1Wme/J
002859   STOCK Tg(Nes-cre)2Wme/J
012859   STOCK Tg(Neurog1-cre)1Jejo/J
005667   STOCK Tg(Neurog3-cre)C1Able/J
008119   STOCK Tg(Neurog3-cre/Esr1*)1Dam/J
012462   STOCK Tg(Nr5a1-cre)7Lowl/J
014158   STOCK Tg(Pax4-cre)1Dam/J
024578   STOCK Tg(Pax6-GFP/cre)1Rilm/J
006207   STOCK Tg(Pcp2-cre)1Amc/J
014099   STOCK Tg(Pmch-cre)1Lowl/J
005965   STOCK Tg(Pomc1-cre)16Lowl/J
012452   STOCK Tg(Rr5-GFP/cre)1Sapc/J
006395   STOCK Tg(Sim1-cre)1Lowl/J
009606   STOCK Tg(Six2-EGFP/cre)1Amc/J
018147   STOCK Tg(Slc17a8-icre)1Edw/SealJ
012586   STOCK Tg(Slc1a3-cre/ERT)1Nat/J
004783   STOCK Tg(Sox2-cre)1Amc/J
008208   STOCK Tg(Stra8-cre)1Reb/J
016236   STOCK Tg(TCF/Lef1-cre/ERT2)1Dje/J
004746   STOCK Tg(Tagln-cre)1Her/J
012708   STOCK Tg(Thy1-cre/ERT2,-EYFP)HGfng/PyngJ
024240   STOCK Tg(Tnnt2-cre)5Blh/JiaoJ
016584   STOCK Tg(Tph2-icre/ERT2)6Gloss/J
003829   STOCK Tg(Wnt1-cre)11Rth Tg(Wnt1-GAL4)11Rth/J
008851   STOCK Tg(Wnt1-cre/ERT)1Alj/J
018281   STOCK Tg(Wnt7a-EGFP/cre)#Bhr/Mmjax
008199   STOCK Tg(dlx6a-cre)1Mekk/J
002471   STOCK Tg(hCMV-cre)140Sau/J
023724   STOCK Tg(mI56i-cre,EGFP)1Kc/J
006224   STOCK Tg(tetO-cre)1Jaw/J
View Strains carrying other alleles of cre     (501 strains)

Additional Web Information

Introduction to Cre-lox technology

Phenotype

Phenotype Information

View Mammalian Phenotype Terms

Mammalian Phenotype Terms provided by MGI
      assigned by genotype

Tg(Zp3-cre)3Mrt/Tg(Zp3-cre)3Mrt

        FVB/N-Tg(Zp3-cre)3Mrt/J
  • reproductive system phenotype
  • reduced female fertility
    • females are subfertile, producing an average of 3.7 pups per litter   (MGI Ref ID J:67903)

The following phenotype information is associated with a similar, but not exact match to this JAX® Mice strain.

Tg(Zp3-cre)3Mrt/0

        B6.FVB-Tg(Zp3-cre)3Mrt
  • reproductive system phenotype
  • reduced female fertility
    • females are subfertile, producing an average of 2.5 pups per litter   (MGI Ref ID J:67903)
View Research Applications

Research Applications
This mouse can be used to support research in many areas including:

Research Tools
Cre-lox System
      Cre Recombinase Expression
      Cre Recombinase Expression: Germline/Embryonic Expression
Genetics Research
      Mutagenesis and Transgenesis
      Mutagenesis and Transgenesis: Cre-lox System
Reproductive Biology Research
      Cre-lox System
      oocyte

cre related

Research Tools
Cre-lox System
Genetics Research
      Mutagenesis and Transgenesis
      Mutagenesis and Transgenesis: Cre-lox System

Genes & Alleles

Gene & Allele Information provided by MGI

 
Allele Symbol Tg(Zp3-cre)3Mrt
Allele Name transgene insertion 3, Gail R Martin
Allele Type Transgenic (Recombinase (cre or Flp) expressing)
Common Name(s) Zp3-cre; Zp3::Cre; delta-R;
Mutation Made ByDr. Gail Martin,   University of California San Francisco
Strain of OriginFVB/N
Site of Expressionprior to first meiotic division
Expressed Gene cre, cre recombinase, bacteriophage P1
Cre recombinase is an enzyme derived from the bacteriophage P1 that specifically recognizes loxP sites. Cre has been shown to effectively mediate the excision of DNA located between loxP sites. After the excision event, the DNA ends recombine leaving a single loxP site in place of the intervening sequence.
Promoter Zp3, zona pellucida glycoprotein 3, mouse, laboratory
Driver Note Zp3
General Note Homozygous transgenic mice are viable and fertile.
Molecular Note This transgene expresses NLS-Cre recombinase under the control of a mouse zona pellucida 3 promoter. This promoter is active in oocytes. No expression was detected in somatic tissues. [MGI Ref ID J:50993]
 
 

Genotyping

Genotyping Information

Genotyping Protocols

Generic Cre Melt Curve Analysis,

MELT


Generic Cre Melt Curve Analysis,

Probe


Generic Cre, Standard PCR


Helpful Links

Genotyping resources and troubleshooting

References

References provided by MGI

Selected Reference(s)

Lewandoski M; Wassarman KM; Martin GR. 1997. Zp3-cre, a transgenic mouse line for the activation or inactivation of loxP-flanked target genes specifically in the female germ line. Curr Biol 7(2):148-51. [PubMed: 9016703]  [MGI Ref ID J:50993]

Additional References

de Vries WN; Binns LT; Fancher KS; Dean J; Moore R; Kemler R; Knowles BB. 2000. Expression of Cre recombinase in mouse oocytes: a means to study maternal effect genes. Genesis 26(2):110-2. [PubMed: 10686600]  [MGI Ref ID J:67903]

Tg(Zp3-cre)3Mrt related

Andreu-Vieyra CV; Chen R; Agno JE; Glaser S; Anastassiadis K; Stewart AF; Matzuk MM. 2010. MLL2 is required in oocytes for bulk histone 3 lysine 4 trimethylation and transcriptional silencing. PLoS Biol 8(8):. [PubMed: 20808952]  [MGI Ref ID J:166778]

Artus J; Piliszek A; Hadjantonakis AK. 2011. The primitive endoderm lineage of the mouse blastocyst: sequential transcription factor activation and regulation of differentiation by Sox17. Dev Biol 350(2):393-404. [PubMed: 21146513]  [MGI Ref ID J:170416]

Astrakhan A; Sather BD; Ryu BY; Khim S; Singh S; Humblet-Baron S; Ochs HD; Miao CH; Rawlings DJ. 2012. Ubiquitous high-level gene expression in hematopoietic lineages provides effective lentiviral gene therapy of murine Wiskott-Aldrich syndrome. Blood 119(19):4395-407. [PubMed: 22431569]  [MGI Ref ID J:185176]

Audouard C; Le Masson F; Charry C; Li Z; Christians ES. 2011. Oocyte-targeted deletion reveals that hsp90b1 is needed for the completion of first mitosis in mouse zygotes. PLoS One 6(2):e17109. [PubMed: 21358806]  [MGI Ref ID J:171086]

Balboula AZ; Schindler K. 2014. Selective disruption of aurora C kinase reveals distinct functions from aurora B kinase during meiosis in mouse oocytes. PLoS Genet 10(2):e1004194. [PubMed: 24586209]  [MGI Ref ID J:211004]

Balthasar N; Dalgaard LT; Lee CE; Yu J; Funahashi H; Williams T; Ferreira M; Tang V; McGovern RA; Kenny CD; Christiansen LM; Edelstein E; Choi B; Boss O; Aschkenasi C; Zhang CY; Mountjoy K; Kishi T; Elmquist JK; Lowell BB. 2005. Divergence of melanocortin pathways in the control of food intake and energy expenditure. Cell 123(3):493-505. [PubMed: 16269339]  [MGI Ref ID J:115192]

Bedzhov I; Liszewska E; Kanzler B; Stemmler MP. 2012. Igf1r signaling is indispensable for preimplantation development and is activated via a novel function of E-cadherin. PLoS Genet 8(3):e1002609. [PubMed: 22479204]  [MGI Ref ID J:183847]

Bhattaram P; Penzo-Mendez A; Sock E; Colmenares C; Kaneko KJ; Vassilev A; Depamphilis ML; Wegner M; Lefebvre V. 2010. Organogenesis relies on SoxC transcription factors for the survival of neural and mesenchymal progenitors. Nat Commun 1:9. [PubMed: 20596238]  [MGI Ref ID J:175338]

Biechele S; Cockburn K; Lanner F; Cox BJ; Rossant J. 2013. Porcn-dependent Wnt signaling is not required prior to mouse gastrulation. Development 140(14):2961-71. [PubMed: 23760955]  [MGI Ref ID J:198636]

Boillee S; Yamanaka K; Lobsiger CS; Copeland NG; Jenkins NA; Kassiotis G; Kollias G; Cleveland DW. 2006. Onset and Progression in Inherited ALS Determined by Motor Neurons and Microglia. Science 312(5778):1389-92. [PubMed: 16741123]  [MGI Ref ID J:109131]

Brydges SD; Mueller JL; McGeough MD; Pena CA; Misaghi A; Gandhi C; Putnam CD; Boyle DL; Firestein GS; Horner AA; Soroosh P; Watford WT; O'Shea JJ; Kastner DL; Hoffman HM. 2009. Inflammasome-mediated disease animal models reveal roles for innate but not adaptive immunity. Immunity 30(6):875-87. [PubMed: 19501000]  [MGI Ref ID J:150054]

Bultman SJ; Gebuhr TC; Pan H; Svoboda P; Schultz RM; Magnuson T. 2006. Maternal BRG1 regulates zygotic genome activation in the mouse. Genes Dev 20(13):1744-54. [PubMed: 16818606]  [MGI Ref ID J:110234]

Chen YT; Tsai MS; Yang TL; Ku AT; Huang KH; Huang CY; Chou FJ; Fan HH; Hong JB; Yen ST; Wang WL; Lin CC; Hsu YC; Su KY; Su IC; Jang CW; Behringer RR; Favaro R; Nicolis SK; Chien CL; Lin SW; Yu IS. 2012. R26R-GR: a Cre-activable dual fluorescent protein reporter mouse. PLoS One 7(9):e46171. [PubMed: 23049968]  [MGI Ref ID J:191943]

Clarke M; Dumon S; Ward C; Jager R; Freeman S; Dawood B; Sheriff L; Lorvellec M; Kralovics R; Frampton J; Garcia P. 2013. MYBL2 haploinsufficiency increases susceptibility to age-related haematopoietic neoplasia. Leukemia 27(3):661-70. [PubMed: 22910183]  [MGI Ref ID J:196804]

Cui X; Wang Y; Tang Y; Liu Y; Zhao L; Deng J; Xu G; Peng X; Ju S; Liu G; Yang H. 2011. Seipin ablation in mice results in severe generalized lipodystrophy. Hum Mol Genet 20(15):3022-30. [PubMed: 21551454]  [MGI Ref ID J:173404]

Ding JH; Xu X; Yang D; Chu PH; Dalton ND; Ye Z; Yeakley JM; Cheng H; Xiao RP; Ross J; Chen J; Fu XD. 2004. Dilated cardiomyopathy caused by tissue-specific ablation of SC35 in the heart. EMBO J 23(4):885-96. [PubMed: 14963485]  [MGI Ref ID J:88432]

Dy P; Smits P; Silvester A; Penzo-Mendez A; Dumitriu B; Han Y; de la Motte CA; Kingsley DM; Lefebvre V. 2010. Synovial joint morphogenesis requires the chondrogenic action of Sox5 and Sox6 in growth plate and articular cartilage. Dev Biol 341(2):346-59. [PubMed: 20206616]  [MGI Ref ID J:160493]

Fernandez-Valdivia R; Jeong J; Mukherjee A; Soyal SM; Li J; Ying Y; Demayo FJ; Lydon JP. 2010. A mouse model to dissect progesterone signaling in the female reproductive tract and mammary gland. Genesis 48(2):106-13. [PubMed: 20029965]  [MGI Ref ID J:158406]

Ferreira R; Wai A; Shimizu R; Gillemans N; Rottier R; von Lindern M; Ohneda K; Grosveld F; Yamamoto M; Philipsen S. 2007. Dynamic regulation of Gata factor levels is more important than their identity. Blood 109(12):5481-90. [PubMed: 17327407]  [MGI Ref ID J:145425]

Fitzpatrick GV; Soloway PD; Higgins MJ. 2002. Regional loss of imprinting and growth deficiency in mice with a targeted deletion of KvDMR1 Nat Genet 32(3):426-31. [PubMed: 12410230]  [MGI Ref ID J:79882]

Froese A; Breher SS; Waldeyer C; Schindler RF; Nikolaev VO; Rinne S; Wischmeyer E; Schlueter J; Becher J; Simrick S; Vauti F; Kuhtz J; Meister P; Kreissl S; Torlopp A; Liebig SK; Laakmann S; Muller TD; Neumann J; Stieber J; Ludwig A; Maier SK; Decher N; Arnold HH; Kirchhof P; Fabritz L; Brand T. 2012. Popeye domain containing proteins are essential for stress-mediated modulation of cardiac pacemaking in mice. J Clin Invest 122(3):1119-30. [PubMed: 22354168]  [MGI Ref ID J:184566]

Gardam S; Sierro F; Basten A; Mackay F; Brink R. 2008. TRAF2 and TRAF3 signal adapters act cooperatively to control the maturation and survival signals delivered to B cells by the BAFF receptor. Immunity 28(3):391-401. [PubMed: 18313334]  [MGI Ref ID J:132877]

Gatto D; Paus D; Basten A; Mackay CR; Brink R. 2009. Guidance of B cells by the orphan G protein-coupled receptor EBI2 shapes humoral immune responses. Immunity 31(2):259-69. [PubMed: 19615922]  [MGI Ref ID J:151883]

Gazdag E; Santenard A; Ziegler-Birling C; Altobelli G; Poch O; Tora L; Torres-Padilla ME. 2009. TBP2 is essential for germ cell development by regulating transcription and chromatin condensation in the oocyte. Genes Dev 23(18):2210-23. [PubMed: 19759265]  [MGI Ref ID J:152449]

Gebuhr TC; Kovalev GI; Bultman S; Godfrey V; Su L; Magnuson T. 2003. The role of Brg1, a catalytic subunit of mammalian chromatin-remodeling complexes, in T cell development. J Exp Med 198(12):1937-49. [PubMed: 14676303]  [MGI Ref ID J:87219]

Gershon E; Plaks V; Aharon I; Galiani D; Reizel Y; Sela-Abramovich S; Granot I; Winterhager E; Dekel N. 2008. Oocyte-directed depletion of connexin43 using the Cre-LoxP system leads to subfertility in female mice. Dev Biol 313(1):1-12. [PubMed: 18005958]  [MGI Ref ID J:130120]

Gilchrist DS; Ure J; Hook L; Medvinsky A. 2003. Labeling of hematopoietic stem and progenitor cells in novel activatable EGFP reporter mice. Genesis 36(3):168-76. [PubMed: 12872249]  [MGI Ref ID J:135901]

Grasa P; Kaune H; Williams SA. 2012. Embryos generated from oocytes lacking complex N- and O-glycans have compromised development and implantation. Reproduction 144(4):455-65. [PubMed: 22919046]  [MGI Ref ID J:191575]

Gu TP; Guo F; Yang H; Wu HP; Xu GF; Liu W; Xie ZG; Shi L; He X; Jin SG; Iqbal K; Shi YG; Deng Z; Szabo PE; Pfeifer GP; Li J; Xu GL. 2011. The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes. Nature 477(7366):606-10. [PubMed: 21892189]  [MGI Ref ID J:176196]

Hagglund AC; Berghard A; Carlsson L. 2013. Canonical Wnt/beta-catenin signalling is essential for optic cup formation. PLoS One 8(12):e81158. [PubMed: 24324671]  [MGI Ref ID J:210692]

He B; Kim TH; Kommagani R; Feng Q; Lanz RB; Jeong JW; DeMayo FJ; Katzenellenbogen BS; Lydon JP; O'Malley BW. 2011. Estrogen-regulated prohibitin is required for mouse uterine development and adult function. Endocrinology 152(3):1047-56. [PubMed: 21209023]  [MGI Ref ID J:173884]

He H; Wang Y; Guo X; Ramchandani S; Ma J; Shen MF; Garcia DA; Deng Y; Multani AS; You MJ; Chang S. 2009. Pot1b deletion and telomerase haploinsufficiency in mice initiate an ATR-dependent DNA damage response and elicit phenotypes resembling dyskeratosis congenita. Mol Cell Biol 29(1):229-40. [PubMed: 18936156]  [MGI Ref ID J:144553]

Herman H; Lu M; Anggraini M; Sikora A; Chang Y; Yoon BJ; Soloway PD. 2003. Trans allele methylation and paramutation-like effects in mice. Nat Genet 34(2):199-202. [PubMed: 12740578]  [MGI Ref ID J:85825]

Holmes R; Chang Y; Soloway PD. 2006. Timing and sequence requirements defined for embryonic maintenance of imprinted DNA methylation at Rasgrf1. Mol Cell Biol 26(24):9564-70. [PubMed: 17030618]  [MGI Ref ID J:117666]

Huang QQ; Perlman H; Huang Z; Birkett R; Kan L; Agrawal H; Misharin A; Gurbuxani S; Crispino JD; Pope RM. 2010. FLIP: a novel regulator of macrophage differentiation and granulocyte homeostasis. Blood 116(23):4968-77. [PubMed: 20724542]  [MGI Ref ID J:167430]

Hui ST; Andres AM; Miller AK; Spann NJ; Potter DW; Post NM; Chen AZ; Sachithanantham S; Jung DY; Kim JK; Davis RA. 2008. Txnip balances metabolic and growth signaling via PTEN disulfide reduction. Proc Natl Acad Sci U S A 105(10):3921-6. [PubMed: 18322014]  [MGI Ref ID J:132756]

Jin N; Gilbert JL; Broaddus RR; Demayo FJ; Jeong JW. 2007. Generation of a Mig-6 conditional null allele. Genesis 45(11):716-21. [PubMed: 17987665]  [MGI Ref ID J:129106]

Kang M; Piliszek A; Artus J; Hadjantonakis AK. 2013. FGF4 is required for lineage restriction and salt-and-pepper distribution of primitive endoderm factors but not their initial expression in the mouse. Development 140(2):267-79. [PubMed: 23193166]  [MGI Ref ID J:191065]

Ko G; Paradise S; Chen H; Graham M; Vecchi M; Bianchi F; Cremona O; Di Fiore PP; De Camilli P. 2010. Selective high-level expression of epsin 3 in gastric parietal cells, where it is localized at endocytic sites of apical canaliculi. Proc Natl Acad Sci U S A :. [PubMed: 21115825]  [MGI Ref ID J:167134]

Komatsu M; Waguri S; Ueno T; Iwata J; Murata S; Tanida I; Ezaki J; Mizushima N; Ohsumi Y; Uchiyama Y; Kominami E; Tanaka K; Chiba T. 2005. Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice. J Cell Biol 169(3):425-34. [PubMed: 15866887]  [MGI Ref ID J:100199]

Kudo NR; Wassmann K; Anger M; Schuh M; Wirth KG; Xu H; Helmhart W; Kudo H; McKay M; Maro B; Ellenberg J; de Boer P; Nasmyth K. 2006. Resolution of chiasmata in oocytes requires separase-mediated proteolysis. Cell 126(1):135-46. [PubMed: 16839882]  [MGI Ref ID J:144684]

Lahmann I; Fabienke M; Henneberg B; Pabst O; Vauti F; Minge D; Illenberger S; Jockusch BM; Korte M; Arnold HH. 2008. The hnRNP and cytoskeletal protein raver1 contributes to synaptic plasticity. Exp Cell Res 314(5):1048-60. [PubMed: 18061163]  [MGI Ref ID J:137591]

Le Bin GC; Munoz-Descalzo S; Kurowski A; Leitch H; Lou X; Mansfield W; Etienne-Dumeau C; Grabole N; Mulas C; Niwa H; Hadjantonakis AK; Nichols J. 2014. Oct4 is required for lineage priming in the developing inner cell mass of the mouse blastocyst. Development 141(5):1001-10. [PubMed: 24504341]  [MGI Ref ID J:208425]

Lee WJ; Kraus P; Lufkin T. 2012. Endogenous tagging of the murine transcription factor Sox5 with hemaglutinin for functional studies. Transgenic Res 21(2):293-301. [PubMed: 21732189]  [MGI Ref ID J:183576]

Levin SI; Meisler MH. 2004. Floxed allele for conditional inactivation of the voltage-gated sodium channel Scn8a (Na(v)1.6). Genesis 39(4):234-9. [PubMed: 15286995]  [MGI Ref ID J:91696]

Li H; Wang D; Singh LS; Berk M; Tan H; Zhao Z; Steinmetz R; Kirmani K; Wei G; Xu Y. 2009. Abnormalities in osteoclastogenesis and decreased tumorigenesis in mice deficient for ovarian cancer G protein-coupled receptor 1. PLoS One 4(5):e5705. [PubMed: 19479052]  [MGI Ref ID J:149315]

Li J; Chen K; Zhu L; Pollard JW. 2006. Conditional deletion of the colony stimulating factor-1 receptor (c-fms proto-oncogene) in mice. Genesis 44(7):328-35. [PubMed: 16823860]  [MGI Ref ID J:110981]

Li X; Tripurani SK; James R; Pangas SA. 2012. Minimal fertility defects in mice deficient in oocyte-expressed Smad4. Biol Reprod 86(1):1-6. [PubMed: 21900682]  [MGI Ref ID J:185785]

Lin PP; Pandey MK; Jin F; Xiong S; Deavers M; Parant JM; Lozano G. 2008. EWS-FLI1 induces developmental abnormalities and accelerates sarcoma formation in a transgenic mouse model. Cancer Res 68(21):8968-75. [PubMed: 18974141]  [MGI Ref ID J:140636]

Matsushita T; Wilcox WR; Chan YY; Kawanami A; Bukulmez H; Balmes G; Krejci P; Mekikian PB; Otani K; Yamaura I; Warman ML; Givol D; Murakami S. 2009. FGFR3 promotes synchondrosis closure and fusion of ossification centers through the MAPK pathway. Hum Mol Genet 18(2):227-40. [PubMed: 18923003]  [MGI Ref ID J:143273]

McMahon HE; Hashimoto O; Mellon PL; Shimasaki S. 2008. Oocyte-specific overexpression of mouse bone morphogenetic protein-15 leads to accelerated folliculogenesis and an early onset of acyclicity in transgenic mice. Endocrinology 149(6):2807-15. [PubMed: 18308851]  [MGI Ref ID J:136039]

Merscher S; Funke B; Epstein JA; Heyer J; Puech A; Lu MM; Xavier RJ; Demay MB; Russell RG; Factor S; Tokooya K; Jore BS; Lopez M; Pandita RK; Lia M; Carrion D; Xu H; Schorle H; Kobler JB; Scambler P; Wynshaw-Boris A; Skoultchi AI; Morrow BE; KucherlapatiR. 2001. TBX1 is responsible for cardiovascular defects in velo-cardio-facial/DiGeorge syndrome. Cell 104(4):619-29. [PubMed: 11239417]  [MGI Ref ID J:67796]

Miyoshi T; Maruhashi M; Van De Putte T; Kondoh H; Huylebroeck D; Higashi Y. 2006. Complementary expression pattern of Zfhx1 genes Sip1 and deltaEF1 in the mouse embryo and their genetic interaction revealed by compound mutants. Dev Dyn 235(7):1941-1952. [PubMed: 16598713]  [MGI Ref ID J:108819]

Muller JM; Deinhardt K; Rosewell I; Warren G; Shima DT. 2007. Targeted deletion of p97 (VCP/CDC48) in mouse results in early embryonic lethality. Biochem Biophys Res Commun 354(2):459-465. [PubMed: 17239345]  [MGI Ref ID J:118184]

Murakami S; Balmes G; McKinney S; Zhang Z; Givol D; de Crombrugghe B. 2004. Constitutive activation of MEK1 in chondrocytes causes Stat1-independent achondroplasia-like dwarfism and rescues the Fgfr3-deficient mouse phenotype. Genes Dev 18(3):290-305. [PubMed: 14871928]  [MGI Ref ID J:88286]

Murphy DJ; Junttila MR; Pouyet L; Karnezis A; Shchors K; Bui DA; Brown-Swigart L; Johnson L; Evan GI. 2008. Distinct thresholds govern Myc's biological output in vivo. Cancer Cell 14(6):447-57. [PubMed: 19061836]  [MGI Ref ID J:142030]

Neves P; Lampropoulou V; Calderon-Gomez E; Roch T; Stervbo U; Shen P; Kuhl AA; Loddenkemper C; Haury M; Nedospasov SA; Kaufmann SH; Steinhoff U; Calado DP; Fillatreau S. 2010. Signaling via the MyD88 adaptor protein in B cells suppresses protective immunity during Salmonella typhimurium infection. Immunity 33(5):777-90. [PubMed: 21093317]  [MGI Ref ID J:167006]

Nishizaki Y; Takagi T; Matsui F; Higashi Y. 2014. SIP1 expression patterns in brain investigated by generating a SIP1-EGFP reporter knock-in mouse. Genesis 52(1):56-67. [PubMed: 24243579]  [MGI Ref ID J:207850]

Nowell CS; Bredenkamp N; Tetelin S; Jin X; Tischner C; Vaidya H; Sheridan JM; Stenhouse FH; Heussen R; Smith AJ; Blackburn CC. 2011. Foxn1 regulates lineage progression in cortical and medullary thymic epithelial cells but is dispensable for medullary sublineage divergence. PLoS Genet 7(11):e1002348. [PubMed: 22072979]  [MGI Ref ID J:177992]

Okano T; Xuan S; Kelley MW. 2011. Insulin-like growth factor signaling regulates the timing of sensory cell differentiation in the mouse cochlea. J Neurosci 31(49):18104-18. [PubMed: 22159122]  [MGI Ref ID J:178908]

Olson DP; Pulinilkunnil T; Cline GW; Shulman GI; Lowell BB. 2010. Gene knockout of Acc2 has little effect on body weight, fat mass, or food intake. Proc Natl Acad Sci U S A 107(16):7598-603. [PubMed: 20368432]  [MGI Ref ID J:159285]

Pallerla SR; Lawrence R; Lewejohann L; Pan Y; Fischer T; Schlomann U; Zhang X; Esko JD; Grobe K. 2008. Altered heparan sulfate structure in mice with deleted NDST3 gene function. J Biol Chem 283(24):16885-94. [PubMed: 18385133]  [MGI Ref ID J:138557]

Pant V; Xiong S; Iwakuma T; Quintas-Cardama A; Lozano G. 2011. Heterodimerization of Mdm2 and Mdm4 is critical for regulating p53 activity during embryogenesis but dispensable for p53 and Mdm2 stability. Proc Natl Acad Sci U S A 108(29):11995-2000. [PubMed: 21730132]  [MGI Ref ID J:174368]

Plaks V; Gershon E; Zeisel A; Jacob-Hirsch J; Neeman M; Winterhager E; Rechavi G; Domany E; Dekel N. 2014. Blastocyst implantation failure relates to impaired translational machinery gene expression. Reproduction 148(1):87-98. [PubMed: 24700326]  [MGI Ref ID J:213754]

Puech A; Saint-Jore B; Merscher S; Russell RG; Cherif D; Sirotkin H; Xu H; Factor S; Kucherlapati R; Skoultchi AI. 2000. Normal cardiovascular development in mice deficient for 16 genes in 550 kb of the velocardiofacial/DiGeorge syndrome region. Proc Natl Acad Sci U S A 97(18):10090-5. [PubMed: 10963672]  [MGI Ref ID J:64380]

Schmidt JV; Levorse JM; Tilghman SM. 1999. Enhancer competition between H19 and Igf2 does not mediate their imprinting. Proc Natl Acad Sci U S A 96(17):9733-8. [PubMed: 10449763]  [MGI Ref ID J:57113]

Schrode N; Saiz N; Di Talia S; Hadjantonakis AK. 2014. GATA6 levels modulate primitive endoderm cell fate choice and timing in the mouse blastocyst. Dev Cell 29(4):454-67. [PubMed: 24835466]  [MGI Ref ID J:213580]

Semjonous NM; Sherlock M; Jeyasuria P; Parker KL; Walker EA; Stewart PM; Lavery GG. 2011. Hexose-6-phosphate dehydrogenase contributes to skeletal muscle homeostasis independent of 11beta-hydroxysteroid dehydrogenase type 1. Endocrinology 152(1):93-102. [PubMed: 21106871]  [MGI Ref ID J:189132]

Shin JY; Fitzpatrick GV; Higgins MJ. 2008. Two distinct mechanisms of silencing by the KvDMR1 imprinting control region. EMBO J 27(1):168-78. [PubMed: 18079696]  [MGI Ref ID J:130529]

Silk AD; Holland AJ; Cleveland DW. 2009. Requirements for NuMA in maintenance and establishment of mammalian spindle poles. J Cell Biol 184(5):677-90. [PubMed: 19255246]  [MGI Ref ID J:146214]

Simpson TI; Pratt T; Mason JO; Price DJ. 2009. Normal ventral telencephalic expression of Pax6 is required for normal development of thalamocortical axons in embryonic mice. Neural Dev 4:19. [PubMed: 19500363]  [MGI Ref ID J:151427]

Solc P; Baran V; Mayer A; Bohmova T; Panenkova-Havlova G; Saskova A; Schultz RM; Motlik J. 2012. Aurora kinase A drives MTOC biogenesis but does not trigger resumption of meiosis in mouse oocytes matured in vivo. Biol Reprod 87(4):85. [PubMed: 22837479]  [MGI Ref ID J:192498]

Stephenson RO; Yamanaka Y; Rossant J. 2010. Disorganized epithelial polarity and excess trophectoderm cell fate in preimplantation embryos lacking E-cadherin. Development 137(20):3383-91. [PubMed: 20826529]  [MGI Ref ID J:165812]

Su X; Paris M; Gi YJ; Tsai KY; Cho MS; Lin YL; Biernaskie JA; Sinha S; Prives C; Pevny LH; Miller FD; Flores ER. 2009. TAp63 prevents premature aging by promoting adult stem cell maintenance. Cell Stem Cell 5(1):64-75. [PubMed: 19570515]  [MGI Ref ID J:151638]

Tachibana-Konwalski K; Godwin J; van der Weyden L; Champion L; Kudo NR; Adams DJ; Nasmyth K. 2010. Rec8-containing cohesin maintains bivalents without turnover during the growing phase of mouse oocytes. Genes Dev 24(22):2505-16. [PubMed: 20971813]  [MGI Ref ID J:166151]

Tao KP; Fong SW; Lu Z; Ching YP; Chan KW; Chan SY. 2011. TSPYL2 Is Important for G1 Checkpoint Maintenance upon DNA Damage. PLoS One 6(6):e21602. [PubMed: 21738728]  [MGI Ref ID J:174549]

Valluet A; Hmitou I; Davis S; Druillennec S; Larcher M; Laroche S; Eychene A. 2010. B-raf alternative splicing is dispensable for development but required for learning and memory associated with the hippocampus in the adult mouse. PLoS One 5(12):e15272. [PubMed: 21203559]  [MGI Ref ID J:168330]

Wang C; Ruther U; Wang B. 2007. The Shh-independent activator function of the full-length Gli3 protein and its role in vertebrate limb digit patterning. Dev Biol 305(2):460-9. [PubMed: 17400206]  [MGI Ref ID J:121609]

Williams SA; Stanley P. 2011. Premature ovarian failure in mice with oocytes lacking core 1-derived O-glycans and complex N-glycans. Endocrinology 152(3):1057-66. [PubMed: 21239444]  [MGI Ref ID J:173879]

Williams SA; Xia L; Cummings RD; McEver RP; Stanley P. 2007. Fertilization in mouse does not require terminal galactose or N-acetylglucosamine on the zona pellucida glycans. J Cell Sci 120(Pt 8):1341-9. [PubMed: 17374637]  [MGI Ref ID J:122012]

Winger Q; Huang J; Auman HJ; Lewandoski M; Williams T. 2006. Analysis of transcription factor AP-2 expression and function during mouse preimplantation development. Biol Reprod 75(3):324-33. [PubMed: 16672719]  [MGI Ref ID J:113442]

Xu X; Yang D; Ding JH; Wang W; Chu PH; Dalton ND; Wang HY; Bermingham JR Jr; Ye Z; Liu F; Rosenfeld MG; Manley JL; Ross J Jr; Chen J; Xiao RP; Cheng H; Fu XD. 2005. ASF/SF2-regulated CaMKIIdelta alternative splicing temporally reprograms excitation-contraction coupling in cardiac muscle. Cell 120(1):59-72. [PubMed: 15652482]  [MGI Ref ID J:96039]

Yamben IF; Rachel RA; Shatadal S; Copeland NG; Jenkins NA; Warming S; Griep AE. 2013. Scrib is required for epithelial cell identity and prevents epithelial to mesenchymal transition in the mouse. Dev Biol 384(1):41-52. [PubMed: 24095903]  [MGI Ref ID J:204591]

Zheng K; Xiol J; Reuter M; Eckardt S; Leu NA; McLaughlin KJ; Stark A; Sachidanandam R; Pillai RS; Wang PJ. 2010. Mouse MOV10L1 associates with Piwi proteins and is an essential component of the Piwi-interacting RNA (piRNA) pathway. Proc Natl Acad Sci U S A :. [PubMed: 20534472]  [MGI Ref ID J:161125]

de Vries WN; Binns LT; Fancher KS; Dean J; Moore R; Kemler R; Knowles BB. 2000. Expression of Cre recombinase in mouse oocytes: a means to study maternal effect genes. Genesis 26(2):110-2. [PubMed: 10686600]  [MGI Ref ID J:67903]

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Production of mice from cryopreserved embryos or sperm occurs in a maximum barrier room, G200.

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Price (US dollars $)
Cryorecovery* $2525.00
Animals Provided

At least two mice that carry the mutation (if it is a mutant strain) will be provided. Their genotypes may not reflect those discussed in the strain description. Please inquire for possible genotypes and see additional details below.

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Cryopreserved. Ready for recovery. Please refer to pricing and supply notes on the strain data sheet for further information.

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    Progeny testing is not required.

    The average number of mice provided from recovery of our cryopreserved strains is 10. The total number of animals provided, their gender and genotype will vary. We will fulfill your order by providing at least two pair of mice, at least one animal of each pair carrying the mutation of interest. Please inquire if larger numbers of animals with specific genotype and genders are needed. Animals typically ship between 10 and 14 weeks from the date of your order. If a second cryorecovery is needed in order to provide the minimum number of animals, animals will ship within 25 weeks. IMPORTANT NOTE: The genotypes of animals provided may not reflect the mating scheme utilized by The Jackson Laboratory prior to cryopreservation, or that discussed in the strain description. Please inquire about possible genotypes which will be recovered for this specific strain. The Jackson Laboratory cannot guarantee the reproductive success of mice shipped to your facility. If the mice are lost after the first three days (post-arrival) or do not produce progeny at your facility, a new order and fee will be necessary.

    Cryorecovery to establish a Dedicated Supply for greater quantities of mice. Mice recovered can be used to establish a dedicated colony to contractually supply you mice according to your requirements. Price by quotation. For more information on Dedicated Supply, please contact JAX® Services, Tel: 1-800-422-6423 (from U.S.A., Canada or Puerto Rico only) or 1-207-288-5845 (from any location).

Pricing for International shipping destinations View USA Canada and Mexico Pricing

Cryopreserved

Cryopreserved Mice - Ready for Recovery

Price (US dollars $)
Cryorecovery* $3283.00
Animals Provided

At least two mice that carry the mutation (if it is a mutant strain) will be provided. Their genotypes may not reflect those discussed in the strain description. Please inquire for possible genotypes and see additional details below.

Standard Supply

Cryopreserved. Ready for recovery. Please refer to pricing and supply notes on the strain data sheet for further information.

Supply Notes

  • Cryorecovery - Standard.
    Progeny testing is not required.

    The average number of mice provided from recovery of our cryopreserved strains is 10. The total number of animals provided, their gender and genotype will vary. We will fulfill your order by providing at least two pair of mice, at least one animal of each pair carrying the mutation of interest. Please inquire if larger numbers of animals with specific genotype and genders are needed. Animals typically ship between 10 and 14 weeks from the date of your order. If a second cryorecovery is needed in order to provide the minimum number of animals, animals will ship within 25 weeks. IMPORTANT NOTE: The genotypes of animals provided may not reflect the mating scheme utilized by The Jackson Laboratory prior to cryopreservation, or that discussed in the strain description. Please inquire about possible genotypes which will be recovered for this specific strain. The Jackson Laboratory cannot guarantee the reproductive success of mice shipped to your facility. If the mice are lost after the first three days (post-arrival) or do not produce progeny at your facility, a new order and fee will be necessary.

    Cryorecovery to establish a Dedicated Supply for greater quantities of mice. Mice recovered can be used to establish a dedicated colony to contractually supply you mice according to your requirements. Price by quotation. For more information on Dedicated Supply, please contact JAX® Services, Tel: 1-800-422-6423 (from U.S.A., Canada or Puerto Rico only) or 1-207-288-5845 (from any location).

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Standard Supply

Cryopreserved. Ready for recovery. Please refer to pricing and supply notes on the strain data sheet for further information.

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The Jackson Laboratory has rigorous genetic quality control and mutant gene genotyping programs to ensure the genetic background of JAX® Mice strains as well as the genotypes of strains with identified molecular mutations. JAX® Mice strains are only made available to researchers after meeting our standards. However, the phenotype of each strain may not be fully characterized and/or captured in the strain data sheets. Therefore, we cannot guarantee a strain's phenotype will meet all expectations. To ensure that JAX® Mice will meet the needs of individual research projects or when requesting a strain that is new to your research, we suggest ordering and performing tests on a small number of mice to determine suitability for your particular project.
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"MICE" means mouse strains, their progeny derived by inbreeding or crossbreeding, unmodified derivatives from mouse strains or their progeny supplied by The Jackson Laboratory ("JACKSON"). "PRODUCTS" means biological materials supplied by JACKSON, and their derivatives. "RECIPIENT" means each recipient of MICE, PRODUCTS, or services provided by JACKSON including each institution, its employees and other researchers under its control. MICE or PRODUCTS shall not be: (i) used for any purpose other than the internal research, (ii) sold or otherwise provided to any third party for any use, or (iii) provided to any agent or other third party to provide breeding or other services. Acceptance of MICE or PRODUCTS from JACKSON shall be deemed as agreement by RECIPIENT to these conditions, and departure from these conditions requires JACKSON's prior written authorization.

No Warranty

MICE, PRODUCTS AND SERVICES ARE PROVIDED “AS IS”. JACKSON EXTENDS NO WARRANTIES OF ANY KIND, EITHER EXPRESS, IMPLIED, OR STATUTORY, WITH RESPECT TO MICE, PRODUCTS OR SERVICES, INCLUDING ANY IMPLIED WARRANTY OF MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE, OR ANY WARRANTY OF NON-INFRINGEMENT OF ANY PATENT, TRADEMARK, OR OTHER INTELLECTUAL PROPERTY RIGHTS.

In case of dissatisfaction for a valid reason and claimed in writing by a purchaser within ninety (90) days of receipt of mice, products or services, JACKSON will, at its option, provide credit or replacement for the mice or product received or the services provided.

No Liability

In no event shall JACKSON, its trustees, directors, officers, employees, and affiliates be liable for any causes of action or damages, including any direct, indirect, special, or consequential damages, arising out of the provision of MICE, PRODUCTS or services, including economic damage or injury to property and lost profits, and including any damage arising from acts or negligence on the part of JACKSON, its agents or employees. Unless prohibited by law, in purchasing or receiving MICE, PRODUCTS or services from JACKSON, purchaser or recipient, or any party claiming by or through them, expressly releases and discharges JACKSON from all such causes of action or damages, and further agrees to defend and indemnify JACKSON from any costs or damages arising out of any third party claims.

MICE and PRODUCTS are to be used in a safe manner and in accordance with all applicable governmental rules and regulations.

The foregoing represents the General Terms and Conditions applicable to JACKSON’s MICE, PRODUCTS or services. In addition, special terms and conditions of sale of certain MICE, PRODUCTS or services may be set forth separately in JACKSON web pages, catalogs, price lists, contracts, and/or other documents, and these special terms and conditions shall also govern the sale of these MICE, PRODUCTS and services by JACKSON, and by its licensees and distributors.

Acceptance of delivery of MICE, PRODUCTS or services shall be deemed agreement to these terms and conditions. No purchase order or other document transmitted by purchaser or recipient that may modify the terms and conditions hereof, shall be in any way binding on JACKSON, and instead the terms and conditions set forth herein, including any special terms and conditions set forth separately, shall govern the sale of MICE, PRODUCTS or services by JACKSON.


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