Strain Name: |
C3Sn.BLiA-Pde6b+/Dn |
|---|---|
Stock Number: |
003648 |
Availability: | Repository- Live |
General Terms and Conditions |
| Genes & Alleles | Pde6b; Pde6b+; |
Product Information
Strain Details
Type JAX® GEMM® Strain - Congenic Additional information on JAX® GEMM® Strains. Type JAX® GEMM® Strain - Mutant Strain Mating System Homozygote x Homozygote (Female x Male) Species laboratory mouse Background Strain C3H/HeSnJ Donor Strain C57BL/LiA Generation N10F15 (22-NOV-06) Appearance
agouti
Related Genotype: A/AStrain Development
The wild type allele of Pde6b from C3A.BLiA-Pde6b+/J (Stock No. 001912)was backcrossed for 10 generations to C3H/HeSnJ at The Jackson Laboratory. This was done for the purpose of generating a hardier control/background strain for use in studies of additional retinal degeneration mutations.
Gene & Allele Details
| Allele Symbol | Pde6b+ | ||
|---|---|---|---|
| Allele Name | wild type | ||
| Mutation Made By | Frank Kooy, University of Antwerp | ||
| Gene Symbol and Name | Pde6b, phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide | ||
| Chromosome | 5 | ||
| Gene Common Name(s) | CSNB3; PDEB; Pdeb; RP40; nmf137; phosphodiesterase, cGMP, rod receptor, beta polypeptide; r; rd; rd-1; rd1; rd10; retinal degeneration; retinal degeneration 1; retinal degeneration 10; | ||
Control Information
| This strain serves as a sighted control for C3H substrains and for studies related to Pde6brd1. | ||
| Considerations for Choosing Controls | ||
Related Strains
Strains carrying Pde6b+ allele
002802 C3.BLiA Pde6b+-Krd/J 001979 C3A.BLiA-Pde6b+.O20-Prph2Rd2/J 001912 C3A.BLiA-Pde6b+/J 004828 FVB.129P2-Pde6b+ Tyrc-ch/AntJ 004808 STOCK Mapttm1(EGFP)Klt Tg(MAPT)8cPdav/J View Strains carrying Pde6b+ (5 strains)
Additional Web Information
Congenic Nomenclature
Genetic Quality Control Annual Report
Animal Health Reports
Room Number A1
Research Applications
This mouse can be used to support research in many areas including:Pde6b+ related
Mouse/Human Gene Homologs
retinitis pigmentosa, wildtype
Sensorineural Research
Retinal Degeneration (wild-type)
Price and Supply Information
| Strain Name: | C3Sn.BLiA-Pde6b+/Dn |
| Stock Number: | 003648 |
Price Details
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Supply Details
| Standard Supply | Repository-Live. A collection of over 1000 strains maintained as live colonies. Individual colonies are sized to meet current customer demand. Delivery for orders of 10 mice or less ranges on average from one to eight weeks; mice are generally shipped between four to six weeks of age with a maximum shipping age of ~nine weeks. Colony sizes do not generally support stringent age specifications for large volumes of mice; however custom orders and larger quantities of mice are easily arranged. Estimated ship dates for all orders provided within 48 hours of order placement. |
|---|---|
| Supply Notes |
Usually shipped between four and eight weeks of age. This strain is included in the Cytogenetic Resource collection. |
| Licensing | See General Terms and Conditions below |
| Control Information | View Control Information in Strain Details. |
General Terms and Conditions
View JAX® Mice & Services Conditions of Use.
The Jackson Laboratory's Genotype Promise
The Jackson Laboratory has rigorous genetic quality control and mutant gene genotyping programs to ensure the genetic background of JAX® Mice strains as well as the genotypes of strains with identified molecular mutations. JAX® Mice strains are only made available to researchers after meeting our standards. However, the phenotype of each strain may not be fully characterized and/or captured in the strain data sheets. Therefore, we cannot guarantee a strain's phenotype will meet all expectations. To ensure that JAX® Mice will meet the needs of individual research projects or when requesting a strain that is new to your research, we suggest ordering and performing tests on a small number of mice to determine suitability for your particular project.Ordering and Purchasing Information
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