JAX Mice Database - 004392 C57BL/6J-Chr 14<A/J>/NaJ

Strain Name:	C57BL/6J-Chr 14^A/J/NaJ
Stock Number:	004392
Availability:	Repository- Live
	Use Restrictions Apply, see *Purchasing Information*

Description
Phenotype
Genes & alleles
Genotyping
Health & husbandry
References
Purchasing information

Description

Strain Information

Former Names C57BL/6J-Chr 14^A/NaJ (Changed: 19-SEP-06 )

C57BL/6-Chr14^A/NaJ (Changed: 22-MAR-06 )

C57BL/6J-14^A/NaJ (Changed: 15-DEC-04 )

Type Consomic;
Additional information on Consomic Mice.

Mating System Homozygote x Homozygote (Female x Male)

Species laboratory mouse

Background Strain C57BL/6J

Donor Strain A/J

H2 Haplotype b

Generation N11F6+13` (24-MAY-08)

Appearance
black
Related Genotype: a/a
Description
A chromosome substitution or consomic strain is an inbred strain with one of its chromosomes replaced by the homologous chromosome of another inbred strain. The C57BL/6J and A/J strains in this set were chosen because they differ in their susceptibility to diseases such as arthritis, asthma, atherosclerosis, cancer, several infectious diseases, inflammatory responses, and physiological, behavioral and sensory phenotypes. Chromosome substitution strain nomenclature is designated as Host Strain - Chromosome #<Donor Strain>/Laboratory code. For example, C57BL/6J-Chr1^A/NaJ carries chromosome 1 for strain A/J (A) on a C57BL/6J background, was constructed in the laboratory of Joseph Nadeau (Na) and is maintained at The Jackson Laboratory (J). Chromosome substitution strains or consomic strains can accelerate quantitative trait loci identification and mapping.
Development
Dr. Joseph Nadeau from Case Western Reserve University developed the C57BL/6J-Chr #^A/NaJ strain set by replacing individual chromosomes from the A/J donor strain into the C57BL/6J host strain using a marker-assisted series of backcrosses (Nadeau et al., 2000). The set was donated to The Jackson Laboratory in 2004.

Control Information

	Control
	000664 C57BL/6J

Considerations for Choosing Controls

Related Strains

B6/A Consomic Panel

004388 C57BL/6J-Chr 10^A/J/NaJ

004389 C57BL/6J-Chr 11^A/J/NaJ

004390 C57BL/6J-Chr 12^A/J/NaJ

004391 C57BL/6J-Chr 13^A/J/NaJ

004393 C57BL/6J-Chr 15^A/J/NaJ

004394 C57BL/6J-Chr 16^A/J/NaJ

004395 C57BL/6J-Chr 17^A/J/NaJ

004396 C57BL/6J-Chr 18^A/J/NaJ

004397 C57BL/6J-Chr 19^A/J/NaJ

004379 C57BL/6J-Chr 1^A/J/NaJ

004380 C57BL/6J-Chr 2^A/J/NaJ

004381 C57BL/6J-Chr 3^A/J/NaJ

004382 C57BL/6J-Chr 4^A/J/NaJ

004383 C57BL/6J-Chr 5^A/J/NaJ

004384 C57BL/6J-Chr 6^A/J/NaJ

004385 C57BL/6J-Chr 7^A/J/NaJ

004386 C57BL/6J-Chr 8^A/J/NaJ

004398 C57BL/6J-Chr X^A/J/NaJ

004399 C57BL/6J-Chr Y^A/J/NaJ

005545 C57BL/6J-mt^A/J/NaJ

View B6/A Consomic Panel (20 strains)

Additional Web Information

Genetic Quality Control Annual Report
JAX^® NOTES, Spring 2004; 493. Chromosome Substitution Strain Panel: A New Tool for Quantitative Trait Loci Analysis.

Phenotype

Phenotype Information

Phenotypic Data
Mouse Phenome Database

Research Applications
This mouse can be used to support research in many areas including:

Research Tools
Genetics Research (Gene Mapping: Tools for QTL Mapping, Segregation and Linkage Analysis)

Genes & Alleles

Gene & Allele Information

Currently there are no related genes or alleles for this strain.

Genotyping

Genotyping Information

This strain will not have a genotyping protocol or one is not currently available.

Helpful Links

Optimizing PCR Protocols

References

Selected Reference(s)

Nadeau JH; Singer JB; Matin A; Lander ES. 2000. Analysing complex genetic traits with chromosome substitution strains. Nat Genet 24(3):221-5. [PubMed: 10700173] [MGI Ref ID J:60756]

Additional References

Singer JB; Hill AE; Burrage LC; Olszens KR; Song J; Justice M; O'Brien WE; Conti DV; Witte JS; Lander ES; Nadeau JH. 2004. Genetic dissection of complex traits with chromosome substitution strains of mice. Science 304(5669):445-8. [PubMed: 15031436] [MGI Ref ID J:90105]

Health & husbandry

Health & Colony Maintenance Information

Animal Health Reports
Room Number FGB27

Colony Maintenance

Diet Information LabDiet® 5K52/5K67

Diet Information	LabDiet® 5K52/5K67

Purchasing information

Pricing, Supply Level & Notes, Controls, General Terms & Conditions

Pricing

Pricing for USA, Canada and Mexico shipping destinations View International Pricing

Weeks of Age Price* Gender Genotypes Provided

Individual Mouse Price $101.60 Female or Male Homozygous

Pairs /Price* Pair Genotype

$203.20 Homozygous x Homozygous

*Price(s) in US dollars ($)

Weeks of Age	Price*	Gender	Genotypes Provided
Individual Mouse Price	$101.60	Female or Male	Homozygous

Pairs /Price*	Pair Genotype
$203.20	Homozygous x Homozygous

Supply Details

Standard Supply	Repository-Live. A collection of over 1000 strains maintained as live colonies. Individual colonies are sized to meet current customer demand. Delivery for orders of 10 mice or less ranges on average from one to eight weeks; mice are generally shipped between four to six weeks of age with a maximum shipping age of ~nine weeks. Colony sizes do not generally support stringent age specifications for large volumes of mice; however custom orders and larger quantities of mice are easily arranged. Estimated ship dates for all orders provided within 48 hours of order placement.
Supply Notes	Histology and Tissue Collection Services are available for all JAX^® Mice strains. For more information, please contact Customer Service at orderquest@jax.org or 1-800-422-6423. Usually shipped between four and eight weeks of age. This strain is included in the Special Mutant Stock Resource collection. Genomic DNA is available for this strain from the Mouse DNA Resource.

Standard Supply

Repository-Live. A collection of over 1000 strains maintained as live colonies. Individual colonies are sized to meet current customer demand. Delivery for orders of 10 mice or less ranges on average from one to eight weeks; mice are generally shipped between four to six weeks of age with a maximum shipping age of ~nine weeks. Colony sizes do not generally support stringent age specifications for large volumes of mice; however custom orders and larger quantities of mice are easily arranged. Estimated ship dates for all orders provided within 48 hours of order placement.

Supply Notes

Histology and Tissue Collection Services are available for all JAX^® Mice strains. For more information, please contact Customer Service at orderquest@jax.org or 1-800-422-6423.
Usually shipped between four and eight weeks of age.
This strain is included in the Special Mutant Stock Resource collection.
Genomic DNA is available for this strain from the Mouse DNA Resource.

Pricing for International shipping destinations View USA, Canada and Mexico Pricing

Weeks of Age Price* Gender Genotypes Provided

Individual Mouse Price $132.10 Female or Male Homozygous

Pairs /Price* Pair Genotype

$264.20 Homozygous x Homozygous

*Price(s) in US dollars ($)

Weeks of Age	Price*	Gender	Genotypes Provided
Individual Mouse Price	$132.10	Female or Male	Homozygous

Pairs /Price*	Pair Genotype
$264.20	Homozygous x Homozygous

Supply Details

Standard Supply	Repository-Live. A collection of over 1000 strains maintained as live colonies. Individual colonies are sized to meet current customer demand. Delivery for orders of 10 mice or less ranges on average from one to eight weeks; mice are generally shipped between four to six weeks of age with a maximum shipping age of ~nine weeks. Colony sizes do not generally support stringent age specifications for large volumes of mice; however custom orders and larger quantities of mice are easily arranged. Estimated ship dates for all orders provided within 48 hours of order placement.
Supply Notes	Histology and Tissue Collection Services are available for all JAX^® Mice strains. For more information, please contact Customer Service at orderquest@jax.org or 1-207-288-5845. Usually shipped between four and eight weeks of age. This strain is included in the Special Mutant Stock Resource collection. Genomic DNA is available for this strain from the Mouse DNA Resource.

Standard Supply

Supply Notes

Histology and Tissue Collection Services are available for all JAX^® Mice strains. For more information, please contact Customer Service at orderquest@jax.org or 1-207-288-5845.
Usually shipped between four and eight weeks of age.
This strain is included in the Special Mutant Stock Resource collection.
Genomic DNA is available for this strain from the Mouse DNA Resource.

View USA, Canada and Mexico Pricing View International Pricing

Control Information

	Control
	000664 C57BL/6J

Considerations for Choosing Controls
USA, Canada and Mexico - Control Pricing Information for Genetically Engineered Mutant Strains.
International - Control Pricing Information for Genetically Engineered Mutant Strains.

General Terms and Conditions

View JAX^® Mice & Services Conditions of Use.

For additional Licensing and Use Restrictions view the link(s) below:
- Use of MICE by companies or for-profit entities requires a license prior to shipping.

The Jackson Laboratory's Genotype Promise

The Jackson Laboratory has rigorous genetic quality control and mutant gene genotyping programs to ensure the genetic background of JAX^® Mice strains as well as the genotypes of strains with identified molecular mutations. JAX^® Mice strains are only made available to researchers after meeting our standards. However, the phenotype of each strain may not be fully characterized and/or captured in the strain data sheets. Therefore, we cannot guarantee a strain's phenotype will meet all expectations. To ensure that JAX^® Mice will meet the needs of individual research projects or when requesting a strain that is new to your research, we suggest ordering and performing tests on a small number of mice to determine suitability for your particular project.

Ordering and Purchasing Information

Purchasing Information
JAX^® Mice Orders
Surgical Services

Contact Information
Orders & Technical Support
Tel: 800.422.6423 or 207.288.5845
Fax: 207.288.6150
Technical Support Email Form

004388	C57BL/6J-Chr 10^A/J/NaJ
004389	C57BL/6J-Chr 11^A/J/NaJ
004390	C57BL/6J-Chr 12^A/J/NaJ
004391	C57BL/6J-Chr 13^A/J/NaJ
004393	C57BL/6J-Chr 15^A/J/NaJ
004394	C57BL/6J-Chr 16^A/J/NaJ
004395	C57BL/6J-Chr 17^A/J/NaJ
004396	C57BL/6J-Chr 18^A/J/NaJ
004397	C57BL/6J-Chr 19^A/J/NaJ
004379	C57BL/6J-Chr 1^A/J/NaJ
004380	C57BL/6J-Chr 2^A/J/NaJ
004381	C57BL/6J-Chr 3^A/J/NaJ
004382	C57BL/6J-Chr 4^A/J/NaJ
004383	C57BL/6J-Chr 5^A/J/NaJ
004384	C57BL/6J-Chr 6^A/J/NaJ
004385	C57BL/6J-Chr 7^A/J/NaJ
004386	C57BL/6J-Chr 8^A/J/NaJ
004398	C57BL/6J-Chr X^A/J/NaJ
004399	C57BL/6J-Chr Y^A/J/NaJ
005545	C57BL/6J-mt^A/J/NaJ

Strain Name:

C57BL/6J-Chr 14A/J/NaJ

Stock Number:

004392

Availability:

Repository- Live

Description

Strain Information

Control Information

Related Strains

Additional Web Information

Phenotype

Phenotype Information

Phenotypic Data

Research Applications

Genes & Alleles

Gene & Allele Information

Genotyping

Genotyping Information

Helpful Links

References

References

Selected Reference(s)

Additional References

Health & husbandry

Health & Colony Maintenance Information

Animal Health Reports

Colony Maintenance

Purchasing information

Pricing, Supply Level & Notes, Controls, General Terms & Conditions

Pricing

Supply Details

Supply Details

Control Information

General Terms and Conditions

The Jackson Laboratory's Genotype Promise

C57BL/6J-Chr 14^A/J/NaJ