Strain Name: |
B6C3-Tg(APPswe,PSEN1dE9)85Dbo/J |
|---|---|
Stock Number: |
004462 |
Availability: |
Level 4 |
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Li T; Wen H; Brayton C; Laird FM; Ma G; Peng S; Placanica L; Wu TC; Crain BJ; Price DL; Eberhart CG; Wong PC. 2007. Moderate reduction of gamma-secretase attenuates amyloid burden and limits mechanism-based liabilities. J Neurosci 27(40):10849-59. [PubMed: 17913918] [MGI Ref ID J:125592]
Liang X; Wang Q; Hand T; Wu L; Breyer RM; Montine TJ; Andreasson K. 2005. Deletion of the prostaglandin E2 EP2 receptor reduces oxidative damage and amyloid burden in a model of Alzheimer's disease. J Neurosci 25(44):10180-7. [PubMed: 16267225] [MGI Ref ID J:102728]
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Zelcer N; Khanlou N; Clare R; Jiang Q; Reed-Geaghan EG; Landreth GE; Vinters HV; Tontonoz P. 2007. Attenuation of neuroinflammation and Alzheimer's disease pathology by liver x receptors. Proc Natl Acad Sci U S A 104(25):10601-6. [PubMed: 17563384] [MGI Ref ID J:122372]