Strain Name: |
C57BL/6J-Cdh23v-9J/J |
|---|---|
Stock Number: |
004819 |
Availability: | Repository-Cryopreserved |
General Terms and Conditions |
| Former Name |
C57BL/6J-Cdh23nmf181/J (Changed: 15-DEC-04
) |
|
C57BL/6J-nmf181/J (Changed: 15-DEC-04
) | |
|
NMF181 (Changed: 15-DEC-04
) | |
| Genes & Alleles | Cdh23; Cdh23v-9J; |
Product Information
Strain Details
Type JAX® GEMM® Strain - Chemically Induced Mutation Additional information on JAX® GEMM® Strains. Type JAX® GEMM® Strain - Coisogenic Type JAX® GEMM® Strain - Mutant Strain Species laboratory mouse H2 Haplotype b Generation N3F1N1p (06-MAR-05) Appearance
black, constantly circling and nervous
Related Genotype: a/a Cdh23v-9J/Cdh23v-9J
black, unaffected
Related Genotype: a/a Cdh23v-9J/+Strain Description
View strain phenotype and additional information on the Neuroscience Mutagenesis Facility web page for Cdh23v-9J entry.
Mammalian Phenotype Terms assigned by genotype |
Gene & Allele Details
| Allele Symbol | Cdh23v-9J | ||
|---|---|---|---|
| Allele Name | waltzer 9 Jackson | ||
| Common Name(s) | Cdh23nmf181; NMF181; neuroscience mutagenesis facility, 181; | ||
| Strain of Origin | C57BL/6J | ||
| Gene Symbol and Name | Cdh23, cadherin 23 (otocadherin) | ||
| Chromosome | 10 | ||
| Gene Common Name(s) | 4930542A03Rik; DFNB12; DKFZp434P2350; FLJ00233; FLJ36499; KIAA1774; KIAA1812; MGC102761; RIKEN cDNA 4930542A03 gene; USH1D; W; age related hearing loss 1; ahl; bob; bobby; bus; bustling; mdfw; modifier of deaf waddler; neuroscience mutagenesis facility, 112; neuroscience mutagenesis facility, 181; neuroscience mutagenesis facility, 252; nmf112; nmf181; nmf252; v; waltzer; | ||
| Molecular Note | The mutant nmf181 has a similar phenotype and mapping position to the waltzer mutant. Complementation testing between nmf181 and a known allele at the waltzer locus, Cdh23nmf112, confirmed the allelic relationship. [J:87349] | ||
Control Information
| Allele | Control | |
|---|---|---|
| Cdh23v-9J | Heterozygote from the colony | |
| Considerations for Choosing Controls | ||
Related Strains
Strains carrying other alleles of Cdh23
001137 129P1/ReJ 000690 129P3/J 002065 129T2/SvEmsJ 000691 129X1/SvJ 000646 A/J 000647 A/WySnJ 003070 ALR/LtJ 003072 ALS/LtJ 002756 B6.CAST-Cdh23Ahl+/Kjn 004502 B6;AKR-Lxl2/J 002432 B6J x B6.C-H2bm1/ByJ-Cdh23v-J/J 001026 BALB/cByJ 000653 BUB/BnJ 005494 C3.129S1(B6)-Grm1rcw/J 000664 C57BL/6J 002552 C57BL/6J-Cdh23v-2J/J 004764 C57BL/6J-Cdh23v-8J/J 003129 C57BL/6J-Epha4rb-2J/J 004820 C57BL/6J-Kcne12J/J 004703 C57BL/6J-Nmf134/J 004811 C57BL/6J-nmf110/J 004812 C57BL/6J-nmf111/J 004747 C57BL/6J-nmf118/J 004656 C57BL/6J-nmf88/J 004391 C57BL/6J-Chr 13A/J/NaJ 004385 C57BL/6J-Chr 7A/J/NaJ 000662 C57BLKS/J 000667 C57BR/cdJ 000668 C57L/J 000669 C58/J 005016 CByJ;B6-Cdh23v-10J/J 000657 CE/J 000670 DBA/1J 001140 DBA/1LacJ 000671 DBA/2J 007048 DBA/2J-Gpnmb+/SjJ 002106 KK/HlJ 000675 LG/J 000676 LP/J 000677 MA/MyJ 001976 NOD/ShiLtJ 002050 NOR/LtJ 000679 P/J 002747 SENCARB/PtJ 002335 SKH2/J 003392 STOCK Crb1rd8/J 000275 V/LeJ View Strains carrying other alleles of Cdh23 (47 strains)
Research Applications
This mouse can be used to support research in many areas including:Cdh23v-9J related
Neurobiology Research
Neuroscience Mutagenesis Facility Strain
Vestibular and Hearing Defects (deafness, nonsyndromic autosomal recessive 12 (DFNB12))
Sensorineural Research
Vestibular and Hearing Defects
References
Additional ReferencesPrice and Supply Information
| Strain Name: | C57BL/6J-Cdh23v-9J/J |
| Stock Number: | 004819 |
Price Details
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Supply Details
| Standard Supply | Repository-Cryopreserved. Must Be Recovered. Please refer to the Supply Notes for further information. |
|---|---|
| Supply Notes |
Cryorecovery of strains needing progeny testing. The recovery process begins when a signed agreement form is returned to the Customer Service Department after order placement. Although results vary by strain, at least two untested males and two untested females (two pairs) will be recovered, typically within 15 weeks of our receipt of the signed agreement form. If the first recovery attempt is unsuccessful or only one pair is recovered, a second recovery will be done, extending the overall recovery time to approximately 25 weeks. However, all pups recovered will be sent. Progeny testing is required to identify the genotype of mice of this strain, as a genotyping assay is not available. This type of testing involves breeding the recovered animals and assessing the phenotype of the offspring in order to identify animals carrying the mutation of interest. We can perform the progeny testing for you as a service or we can ship all recovered animals (at least two untested pairs) to you for progeny testing at your facility. If you perform the progeny testing, there is NO guarantee that a carrier will be identified. If we perform progeny testing as a service, additional breeding time will be required. In this case, when a male and female (one pair) are identified that carry the mutation, they and their offspring will be shipped. Delivery time for strains requiring progeny testing often exceeds 25 weeks and may take 12 months or more due to the difficulties in breeding some strains. The progeny testing cost is in addition to the recovery cost and is based on the number of boxes used and the time taken to produce the mice identified as carrying the mutation. Please note that identified pairs may not reflect the mating scheme utilized by The Jackson Laboratory prior to cryopreservation of the strain. Mating schemes are sometimes modified for successful cryopreservation. Please contact Customer Service for more information on the cost of progeny testing for a strain: Tel: 800-422-6423 or 207-288-5845. Cryorecovery to establish a Dedicated Supply for greater quantities of mice |
| Licensing | See General Terms and Conditions below |
| Control Information | View Control Information in Strain Details. |
General Terms and Conditions
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The Jackson Laboratory has rigorous genetic quality control and mutant gene genotyping programs to ensure the genetic background of JAX® Mice strains as well as the genotypes of strains with identified molecular mutations. JAX® Mice strains are only made available to researchers after meeting our standards. However, the phenotype of each strain may not be fully characterized and/or captured in the strain data sheets. Therefore, we cannot guarantee a strain's phenotype will meet all expectations. To ensure that JAX® Mice will meet the needs of individual research projects or when requesting a strain that is new to your research, we suggest ordering and performing tests on a small number of mice to determine suitability for your particular project.Ordering and Purchasing Information
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