Go to JAX® Mice Query Form

Strain Name:

CByJ;B6-Cdh23v-10J/J

Stock Number:

005016

Availability:

Repository-Cryopreserved

Price and Supply Information

General Terms and Conditions

Former Name      CByJ;B6-Cdh23nmf252/J    (Changed: 15-DEC-04 )
      CByJ;B6-nmf252/J    (Changed: 15-DEC-04 )
      NMF252    (Changed: 15-DEC-04 )
Genes & Alleles   Cdh23;   Cdh23v-10J;

Product Information

Strain Details

Type JAX® GEMM® Strain - Chemically Induced Mutation
Additional information on JAX® GEMM® Strains.
Type JAX® GEMM® Strain - Congenic
Type JAX® GEMM® Strain - Mutant Stock
Specieslaboratory mouse
H2 Haplotypeb, d or b/d (unknown)
GenerationN3F2pN1 (12-JUN-05)

Appearance
Stock is assorting for Tyrp1b, Tyrc,A and a, ; consequently the mice are an assortment of colors, including black, brown, light (brown) and dark (black) agouti and albino.

head tilt and head tossing
Related Genotype: Cdh23v-10J/Cdh23v-10J;

Strain Description
View strain phenotype and additional information on the Neuroscience Mutagenesis Facility web page for Cdh23v-10J entry.

Mammalian Phenotype Terms assigned by genotype

Cdh23v-10J/Cdh23v-10J

        involves: BALB/cByJ * C57BL/6
  • behavior/neurological phenotype
  • abnormal stationary movement (MGI Ref ID J:87349)
    • head tilt (MGI Ref ID J:87349)
      • head tilt exhibited by weaning age
  • circling (MGI Ref ID J:87349)
    • circling behavior exhibited by weaning age
  • hearing/vestibular/ear phenotype
  • abnormal brainstem auditory evoked potential (MGI Ref ID J:87349)
    • two mice tested for auditory brainstem response at 6 weeks of age were found to be deaf
  • circling (MGI Ref ID J:87349)
    • circling behavior exhibited by weaning age
  • deafness (MGI Ref ID J:87349)
    • two mice tested for auditory brainstem response at 6 weeks of age were found to be deaf
  • head tilt (MGI Ref ID J:87349)
    • head tilt exhibited by weaning age

Gene & Allele Details

Allele Symbol Cdh23v-10J
Allele Name waltzer 10 Jackson
Common Name(s) Cdh23nmf252; NMF252; neuroscience mutagenesis facility, 252;
Strain of OriginC57BL/6J
Gene Symbol and Name Cdh23, cadherin 23 (otocadherin)
Chromosome 10
Gene Common Name(s) 4930542A03Rik; DFNB12; DKFZp434P2350; FLJ00233; FLJ36499; KIAA1774; KIAA1812; MGC102761; RIKEN cDNA 4930542A03 gene; USH1D; age related hearing loss 1; ahl; bob; bobby; bus; bustling; mdfw; modifier of deaf waddler; neuroscience mutagenesis facility, 112; neuroscience mutagenesis facility, 181; neuroscience mutagenesis facility, 252; nmf112; nmf181; nmf252; v; waltzer;
Molecular Note The mutant nmf252 has a similar phenotype and mapping position to the waltzer mutant. Complementation testing between nmf252 and Cdh23v-2J confirmed the allelic relationship. [MGI Ref ID J:87349]

Control Information

  Allele   Control
 Cdh23v-10J  Untyped from the colony
 
  Considerations for Choosing Controls
  Control Pricing Information for JAX® GEMM® Strains

Related Strains

Strains carrying other alleles of Cdh23
001137   129P1/ReJ
000690   129P3/J
002065   129T2/SvEmsJ
000691   129X1/SvJ
000646   A/J
000647   A/WySnJ
003070   ALR/LtJ
003072   ALS/LtJ
008288   B6(Cg)-Cdh23v-11J/J
002756   B6.CAST-Cdh23Ahl+/Kjn
004502   B6;AKR-Lxl2/J
002432   B6J x B6.C-H2bm1/ByJ-Cdh23v-J/J
001026   BALB/cByJ
000653   BUB/BnJ
005494   C3.129S1(B6)-Grm1rcw/J
000664   C57BL/6J
002552   C57BL/6J-Cdh23v-2J/J
004764   C57BL/6J-Cdh23v-8J/J
004819   C57BL/6J-Cdh23v-9J/J
003129   C57BL/6J-Epha4rb-2J/J
004820   C57BL/6J-Kcne12J/J
004703   C57BL/6J-Kcnq2Nmf134/J
004811   C57BL/6J-nmf110/J
004812   C57BL/6J-nmf111/J
004747   C57BL/6J-nmf118/J
004656   C57BL/6J-nmf88/J
004391   C57BL/6J-Chr 13A/J/NaJ
004385   C57BL/6J-Chr 7A/J/NaJ
000662   C57BLKS/J
000667   C57BR/cdJ
000668   C57L/J
000669   C58/J
000657   CE/J
000670   DBA/1J
001140   DBA/1LacJ
000671   DBA/2J
007048   DBA/2J-Gpnmb+/SjJ
002106   KK/HlJ
000675   LG/J
000676   LP/J
000677   MA/MyJ
001976   NOD/ShiLtJ
002050   NOR/LtJ
000679   P/J
002747   SENCARB/PtJ
002335   SKH2/J
003392   STOCK Crb1rd8/J
000275   V/LeJ
View Strains carrying other alleles of Cdh23     (48 strains)

Additional Web Information

Genetic Quality Control Annual Report

Research Applications

This mouse can be used to support research in many areas including:

Cdh23v-10J related

Neurobiology Research
Neuroscience Mutagenesis Facility Strain
Vestibular and Hearing Defects (deafness, nonsyndromic autosomal recessive 12 (DFNB12))

Sensorineural Research
Vestibular and Hearing Defects

References

Additional References

Price and Supply Information

Strain Name: CByJ;B6-Cdh23v-10J/J
Stock Number: 005016

Price Details

IMPORTANT NOTE: Prices are based on shipping destination. The shipping destinations are:

*Pricing for Shipping Destination selected:

        International

Price(s) in US dollars ($)
Cryorecovery Fee $2470.00

Supply Details

Standard SupplyRepository-Cryopreserved. Must Be Recovered. Please refer to the Supply Notes for further information.
Supply Notes Cryorecovery - Standard.
The recovery process begins when a signed agreement form is returned to the Customer Service Department after order placement. Although results vary by strain, at least two males and two females (two pairs) will be provided, typically within 15 weeks of our receipt of the signed agreement form. If the first recovery attempt is unsuccessful or only one pair is recovered, a second recovery will be done, extending the delivery time to approximately 25 weeks. At least one member of each pair will be of known genotype and will carry the mutation if it is a mutant strain. Please note that pairs may not reflect the mating scheme utilized by The Jackson Laboratory prior to cryopreservation of the strain. Mating schemes are sometimes modified for successful cryopreservation. Price represents a repository maintenance fee, which includes the cost of recovery of the strain from the cryopreservation resource and the periodic replacement of the frozen embryos used for recovery.

Cryorecovery to establish a Dedicated Supply for greater quantities of mice.
One to two pairs will be recovered to establish a Dedicated Supply of mice. Price by quotation. For more information on Dedicated Supply, please contact JAX® Services: Tel: 1-800-422-6423 or 1-207-288-5845; Email: jaxservices@jax.org.
This strain is included in the Neuroscience Mutagenesis Facility (NMF).
Genomic DNA is available for this strain from the Mouse DNA Resource.

LicensingSee General Terms and Conditions below  
Control InformationView Control Information in Strain Details.
View Control Pricing Information for JAX® Strains.

General Terms and Conditions

View JAX® Mice & Services Conditions of Use.

The Jackson Laboratory's Genotype Promise

The Jackson Laboratory has rigorous genetic quality control and mutant gene genotyping programs to ensure the genetic background of JAX® Mice strains as well as the genotypes of strains with identified molecular mutations. JAX® Mice strains are only made available to researchers after meeting our standards. However, the phenotype of each strain may not be fully characterized and/or captured in the strain data sheets. Therefore, we cannot guarantee a strain's phenotype will meet all expectations. To ensure that JAX® Mice will meet the needs of individual research projects or when requesting a strain that is new to your research, we suggest ordering and performing tests on a small number of mice to determine suitability for your particular project.
Ordering and Purchasing Information

      Purchasing Information
      JAX® Mice Orders
      Surgical Services

Contact Information
Orders & Technical Support
Tel: 800.422.6423 or 207.288.5845
Fax: 207.288.6150
Technical Support Email Form

Go to JAX® Mice Query Form

(2.13)