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Former Name	B6.D2-Chr2D/LusJ    (Changed: 12-JUL-05 )
Genes & Alleles	D2Mit405;   D2Mit457;   ;

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Product Information

Strain Details

Type JAX® GEMM® Strain - Congenic Additional information on JAX® GEMM® Strains. Species laboratory mouse Background Strain C57BL/6J Donor Strain DBA/2J Donating Investigator Aldons Lusis,   University of California at Los Angeles H2 Haplotype b Generation ?+F4 (06-DEC-07)

Appearance
black
Related Genotype: a/a

Strain Development
This congenic panel was initiated by a cross of B6D2F1/J (Stock #100006) females to C57BL/6J males. Male progeny at each generation were selected by marker assisted genome scan and were backcrossed to C57BL/6J females to produce the N3-N6 generations. All animals in the panel carry a C57BL/6J Y chromosome. Sibling pairs at the N6 generation were intercrossed to produce homozygotes. Iakoubova OA, et. al. provides a more detailed explanation of the chromosome intervals. Dr. Lusis donated the panel to The Jackson Laboratory in 2004.

Gene & Allele Details

Gene Symbol and Name		D2Mit405, DNA segment, Chr 2, Massachusetts Institute of Technology 405
Chromosome		2
Gene Symbol and Name		D2Mit457, DNA Segment, Chr 2, Massachusetts Institute of Technology 457
Chromosome		2

Control Information

	Control
	000664 C57BL/6J
Considerations for Choosing Controls

Colony Maintenance

Diet Information	LabDiet® 5K52/5K67

Related Strains

Other Related Strains

	005188	B6.D2-(D13Mit198-D13Mit314)/LusJ
	005187	B6.D2-(D13Mit79-D13Mit198)/LusJ
	005206	B6.D2-(D18Mit33-D18Mit144)/LusJ
	005152	B6.D2-(D2Mit1-rs3681655)/LusJ
	005155	B6.D2-(D3Mit149-rs3726528)/LusJ
	005167	B6.D2-(D6Mit149-D6Mit15)/LusJ
	005166	B6.D2-(D6Mit86-D6Mit198)/LusJ
	005173	B6.D2-(D8Mit256-D8Mit42)/LusJ
	005174	B6.D2-(D8Mit318-D8Mit56)/LusJ
	005175	B6.D2-(D9Mit329-D9Mit115)/LusJ
	005156	B6.D2-(rs3653796-rs3022971)/LusJ
	005205	B6.D2-(rs3696933-rs3672215)/LusJ

View Other Related Strains     (12 strains)

Additional Web Information

Congenic Nomenclature

Research Applications

This mouse can be used to support research in many areas including:

Research Tools
Genetics Research (Gene Mapping: Tools for QTL Mapping, Segregation and Linkage Analysis)

References

Selected Reference(s)

Davis RC; Schadt EE; Smith DJ; Hsieh EW; Cervino AC; van Nas A; Rosales M; Doss S; Meng H; Allayee H; Lusis AJ. 2005. A genome-wide set of congenic mouse strains derived from DBA/2J on a C57BL/6J background. Genomics 86(3):259-70. [PubMed: 16039824]  [MGI Ref ID J:107521]

Iakoubova OA; Olsson CL; Dains KM; Ross DA; Andalibi A; Lau K; Choi J; Kalcheva I; Cunanan M; Louie J; Nimon V; Machrus M; Bentley LG; Beauheim C; Silvey S; Cavalcoli J; Lusis AJ; West DB. 2001. Genome-tagged mice (GTM): two sets of genome-wide congenic strains. Genomics 74(1):89-104. [PubMed: 11374905]  [MGI Ref ID J:69881]

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Price and Supply Information

Strain Name:	B6.D2-(D2Mit405-D2Mit457)/LusJ
Stock Number:	005154

 

This strain is currently Under Development for Cryopreservation Repository.
To register your interest in this strain go to the Strain Interest Form.

Estimated Available for Sale Date:

Please note: Estimated available for sale dates are provided to keep customers better informed on strains under development. Please note that our Colony Managers routinely monitor the target date and edit it based on breeding performance and other factors. The length of time it takes to make a new strain available for sale depends on genotype, age, number of animals sent by the Donating Investigator, breeding performance, additional strain development (backcrossing, making homozygous), and anticipated demand for the strain/interest registered.

View All Strains Under Development

Supply Details

Standard Supply	Under Development for Cryopreservation Repository
Supply Notes	This strain is included in the Mouse Mutant Resource collection.
Licensing	See General Terms and Conditions below for Licensing and Use Restrictions
Control Information	View Control Information in Strain Details.

General Terms and Conditions

View JAX^® Mice & Services Conditions of Use.

For additional Licensing and Use Restrictions view the link(s) below:
- Use of MICE by companies or for-profit entities requires a license prior to shipping.

The Jackson Laboratory's Genotype Promise

The Jackson Laboratory has rigorous genetic quality control and mutant gene genotyping programs to ensure the genetic background of JAX^® Mice strains as well as the genotypes of strains with identified molecular mutations. JAX^® Mice strains are only made available to researchers after meeting our standards. However, the phenotype of each strain may not be fully characterized and/or captured in the strain data sheets. Therefore, we cannot guarantee a strain's phenotype will meet all expectations. To ensure that JAX^® Mice will meet the needs of individual research projects or when requesting a strain that is new to your research, we suggest ordering and performing tests on a small number of mice to determine suitability for your particular project.

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