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- Description
- Phenotype
- Genes & alleles
- Genotyping
- Health & husbandry
- References
- Purchasing information
- Terms of Use
Description
Strain Information
Type Chemically Induced Mutation; Coisogenic; Mutant Strain; Additional information on Genetically Engineered Mutant Mice. Species laboratory mouse Generation N4F5 (27-NOV-07) Appearance
black
Related Genotype: a/aDescription
View strain phenotype and additional information on the Neuroscience Mutagenesis Facility web page for nmf246 entry.
Control Information
| Control | ||
|---|---|---|
| Heterozygote from the colony | ||
| 000664 C57BL/6J | ||
| Considerations for Choosing Controls | ||
Phenotype
Phenotype Information
View Mammalian Phenotype Terms
Mammalian Phenotype Terms
assigned by genotype
nmf246/nmf246
C57BL/6J-nmf246/J
- vision/eye phenotype
- retinal degeneration (MGI Ref ID J:87349)
- by 12 weeks of age, retinas of homozygous mutant mice present a grainy appearance and/or spotting upon ophthamoscopic examination
- standard pathology examination of two mutants (aged 112 and 401 days) revealed retinal degeneration
This mouse can be used to support research in many areas including:nmf246 related
Neurobiology Research
Neuroscience Mutagenesis Facility Strain
Research Tools
Sensorineural Research (retinal spots)
Sensorineural Research
Retinal Degeneration
Genes & Alleles
Gene & Allele Information
| Allele Symbol | nmf246 | ||
|---|---|---|---|
| Allele Name | neuroscience mutagenesis facility, 246 | ||
| Allele Type | Chemically induced (ENU) | ||
| Common Name(s) | NMF246; | ||
| Strain of Origin | C57BL/6J | ||
| Molecular Note | This phenotypic mutation was identified in an ENU mutagenesis screen. | ||
Genotyping
Genotyping Information
This strain will not have a genotyping protocol or one is not currently available.
Helpful Links
Optimizing PCR Protocols
References
References
Additional References
nmf246 relatedJAX Neuroscience Mutagenesis Facility URL: http://www.jax.org/nmf. 2004. Heritable mouse mutants from JAX NMF ENU Mutagenesis Program MGI Direct Data Submission :. [MGI Ref ID J:87349]
Health & husbandry
Health & Colony Maintenance Information
Currently there no information available for this strain. This may be due to the supply level of this strain.
Purchasing information
Pricing, Supply Level & Notes, Controls, General Terms & Conditions
Pricing
| Pricing for USA, Canada and Mexico shipping destinations |
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Weeks of Age Price* Gender Genotypes Provided Individual Mouse Price $136.20 Female or Male Heterozygous for nmf246 $136.20 Female or Male Homozygous for nmf246 *Price(s) in US dollars ($)
Pairs /Price* Pair Genotype $272.40 Heterozygous for nmf246 x Heterozygous for nmf246 $272.40 Heterozygous for nmf246 x Homozygous for nmf246 $272.40 Homozygous for nmf246 x Heterozygous for nmf246 $272.40 Homozygous for nmf246 x Homozygous for nmf246
Additional Supply Details
| Supply Notes |
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| Pricing for International shipping destinations |
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Weeks of Age Price* Gender Genotypes Provided Individual Mouse Price $177.10 Female or Male Heterozygous for nmf246 $177.10 Female or Male Homozygous for nmf246 *Price(s) in US dollars ($)
Pairs /Price* Pair Genotype $354.20 Heterozygous for nmf246 x Heterozygous for nmf246 $354.20 Heterozygous for nmf246 x Homozygous for nmf246 $354.20 Homozygous for nmf246 x Heterozygous for nmf246 $354.20 Homozygous for nmf246 x Homozygous for nmf246
Additional Supply Details
| Supply Notes |
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Supply Details
| Standard Supply | Research Strain. Availability determined by The Jackson Laboratory scientist holding the strain. |
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| Supply Notes |
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Control Information
| Control | ||
|---|---|---|
| Heterozygote from the colony | ||
| 000664 C57BL/6J | ||
| Considerations for Choosing Controls | ||
| USA, Canada and Mexico - Control Pricing Information for Genetically Engineered Mutant Strains. | ||
| International - Control Pricing Information for Genetically Engineered Mutant Strains. | ||
General Terms and Conditions
See Terms of Use
The Jackson Laboratory's Genotype Promise
The Jackson Laboratory has rigorous genetic quality control and mutant gene genotyping programs to ensure the genetic background of JAX® Mice strains as well as the genotypes of strains with identified molecular mutations. JAX® Mice strains are only made available to researchers after meeting our standards. However, the phenotype of each strain may not be fully characterized and/or captured in the strain data sheets. Therefore, we cannot guarantee a strain's phenotype will meet all expectations. To ensure that JAX® Mice will meet the needs of individual research projects or when requesting a strain that is new to your research, we suggest ordering and performing tests on a small number of mice to determine suitability for your particular project.Ordering and Purchasing Information
Purchasing Information
JAX® Mice Orders
Surgical Services
Contact Information
Orders & Technical Support
Tel: 800.422.6423 or 207.288.5845
Fax: 207.288.6150
Technical Support Email Form
Terms of Use
Terms of Use
General Terms and Conditions
Contact information
General inquiries
Contracts Administration
| phone: | 207-288-6470 |
| fax: | 207-288-6655 |
JAX® Mice & Services Conditions of Use
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The foregoing represents the General Terms and Conditions applicable to The Jackson Laboratory’s MICE, products and services. In addition, special terms and conditions of sale of certain MICE, products and services may be set forth separately in The Jackson Laboratory web pages, catalogs, price lists, contracts, and/or other documents, and these special terms and conditions shall also govern the sale of these MICE, products and services by The Jackson Laboratory, and by its licensees and distributors.
Acceptance of delivery of MICE, products or services shall be deemed agreement to these terms and conditions. No purchase order or other document transmitted by purchaser or recipient that may modify the terms and conditions hereof, shall be in any way binding on The Jackson Laboratory, and instead the terms and conditions set forth herein, including any special terms and conditions set forth separately, shall govern the sale of MICE, products services by The Jackson Laboratory.