Strain Name: |
C57BL/6J-Myo6sv-3J/J |
|---|---|
Stock Number: |
005749 |
Availability: | Repository-Cryopreserved |
General Terms and Conditions |
| Former Name |
C57BL/6J-nmf464/J (Changed: 02-MAY-07
) |
| Genes & Alleles | Myo6; Myo6sv-3J; |
Product Information
Strain Details
Type JAX® GEMM® Strain - Chemically Induced Mutation Additional information on JAX® GEMM® Strains. Type JAX® GEMM® Strain - Coisogenic Type JAX® GEMM® Strain - Mutant Strain Species laboratory mouse Generation N2F2pN1 Important Note
The C57BL/6J background strain is homozygous for the age related hearing loss mutation Cdh23ahl, which on this background causes progressive hearing loss with onset after 10 months of age.Strain Development
This strain was produced by the Neuroscience Mutagenesis Facility at The Jackson Laboratory.
Mammalian Phenotype Terms assigned by genotype |
Gene & Allele Details
| Allele Symbol | Myo6sv-3J | ||
|---|---|---|---|
| Allele Name | Snell's waltzer 3 Jackson | ||
| Common Name(s) | nmf464; | ||
| Strain of Origin | C57BL/6J | ||
| Gene Symbol and Name | Myo6, myosin VI | ||
| Chromosome | 9 | ||
| Gene Common Name(s) | BC029719; DFNA22; DFNB37; KIAA0389; RGD1560646; Snell's waltzer; cDNA sequence BC029719; sv; | ||
| Molecular Note | A complementation test with the original Snell's waltzer mutation showed this to be allelic with it. [MGI Ref ID J:87349] | ||
Related Strains
Strains carrying other alleles of Myo6
008456 129S1/SvImJ-Myo6sv-4J/J 000578 B6 x STOCK Tyrc-ch Bmp5se +/+ Myo6sv/J 006124 B6.Cg-Myo6sv-2J/J View Strains carrying other alleles of Myo6 (3 strains)
Research Applications
This mouse can be used to support research in many areas including:
Neurobiology Research
Neuroscience Mutagenesis Facility Strain
Vestibular and Hearing Defects
Sensorineural Research
Vestibular and Hearing Defects
References
Additional ReferencesPrice and Supply Information
| Strain Name: | C57BL/6J-Myo6sv-3J/J |
| Stock Number: | 005749 |
Price Details
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Supply Details
| Standard Supply | Repository-Cryopreserved. Must Be Recovered. Please refer to pricing and supply notes for further information. |
|---|---|
| Supply Notes |
Cryorecovery - Standard. The recovery process begins when a signed agreement form is returned to the Customer Service Department after order placement. Although results vary by strain, at least two males and two females (two pairs) will be provided, typically within 15 weeks of our receipt of the signed agreement form. If the first recovery attempt is unsuccessful or only one pair is recovered, a second recovery will be done, extending the delivery time to approximately 25 weeks. At least one member of each pair will be of known genotype and will carry the mutation if it is a mutant strain. Please note that pairs may not reflect the mating scheme utilized by The Jackson Laboratory prior to cryopreservation of the strain. Mating schemes are sometimes modified for successful cryopreservation. Price represents a repository maintenance fee, which includes the cost of recovery of the strain from the cryopreservation resource and the periodic replacement of the frozen embryos used for recovery. Cryorecovery to establish a Dedicated Supply for greater quantities of mice. |
| Licensing | See General Terms and Conditions below |
General Terms and Conditions
View JAX® Mice & Services Conditions of Use.
The Jackson Laboratory's Genotype Promise
The Jackson Laboratory has rigorous genetic quality control and mutant gene genotyping programs to ensure the genetic background of JAX® Mice strains as well as the genotypes of strains with identified molecular mutations. JAX® Mice strains are only made available to researchers after meeting our standards. However, the phenotype of each strain may not be fully characterized and/or captured in the strain data sheets. Therefore, we cannot guarantee a strain's phenotype will meet all expectations. To ensure that JAX® Mice will meet the needs of individual research projects or when requesting a strain that is new to your research, we suggest ordering and performing tests on a small number of mice to determine suitability for your particular project.Ordering and Purchasing Information
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