Strain Name: |
B6.129P2-Cxcr3tm1Dgen/J |
|---|---|
Stock Number: |
005796 |
Availability: | Repository- Live |
General Terms and Conditions |
| Genes & Alleles | Cxcr3; Cxcr3tm1Dgen; |
Product Information
Strain Details
Type JAX® GEMM® Strain - Congenic Additional information on JAX® GEMM® Strains. Type JAX® GEMM® Strain - Mutant Strain Type JAX® GEMM® Strain - Targeted Mutation Mating System Homozygote x Hemizygote (Female x Male) Species laboratory mouse Generation ?+N2f3 (31-DEC-07) Strain Description
This targeted mutant was created and characterized by Deltagen, Inc. View phenotypic data developed by Deltagen.Strain Development
The construct insert is reported to be "SA-IRES-lacZ-Neo555G/Kan." Upon arrival at The Jackson Laboratory, these mice had been backcrossed at least 6 generations to C57BL/6 mice.
Mammalian Phenotype Terms assigned by genotype |
Gene & Allele Details
| Allele Symbol | Cxcr3tm1Dgen | ||
|---|---|---|---|
| Allele Name | targeted mutation 1, Deltagen | ||
| Strain of Origin | 129P2/OlaHsd | ||
| ES Cell Line Name | E14 | ||
| ES Cell Line Strain | 129P2/OlaHsd | ||
| Site of Expression | Faint lacZ expression is detected in some regions of wholemount brain. | ||
| Gene Symbol and Name | Cxcr3, chemokine (C-X-C motif) receptor 3 | ||
| Chromosome | X | ||
| Gene Common Name(s) | CD182; CD183; CKR-L2; CMKAR3; Cmkar3; GPR9; IP10-R; Mig-R; MigR; chemokine (C-X-C) receptor 3; | ||
| Molecular Note | A bacterial lacZ gene was inserted into the gene such that the endogenous gene promoter drives expression of beta-galactosidase. RT-PCR analysis detects a high level of gene transcript in spleen, lymph nodes and ovary, moderate levels in cerebellum, lung, liver, pancreas, kidney, thymus, bone marrow, skin, gallbladder, urinary bladder, pituitary gland, adrenal gland, salivary gland, colon, epididymis, seminal vesicle, coagulating gland, uterus and white fat, and low levels in whole brain, cortex, subcortical region, brainstem, olfactory bulb, spinal cord, eye, Harderian glands, heart, skeletal muscle, tongue, stomach, small intestine, cecum, testis and prostate gland. However, faint beta-galactosidase expression from this allele is detectable in onlyin whole mount brain. | ||
Control Information
| Control | ||
|---|---|---|
| 000664 C57BL/6J | ||
| Considerations for Choosing Controls | ||
Genotyping Protocols
Cxcr3tm1Dgen
Colony Maintenance
| Diet Information | LabDiet® 5K52/5K67 |
|---|
Related Strains
lacZ Expression Strains
View lacZ Expression Strains (174 strains)
Additional Web Information
Congenic Nomenclature
Fluorescent Proteins/lacZ Systems
Animal Health Reports
Room Number AX12
Research Applications
This mouse can be used to support research in many areas including:
Cxcr3tm1Dgen relatedResearch Tools
lacZ Expression
Immunology and Inflammation Research
References
Additional ReferencesPrice and Supply Information
| Strain Name: | B6.129P2-Cxcr3tm1Dgen/J |
| Stock Number: | 005796 |
Price Details
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Supply Details
| Standard Supply | Repository-Live. A collection of over 1000 strains maintained as live colonies. Individual colonies are sized to meet current customer demand. Delivery for orders of 10 mice or less ranges on average from one to eight weeks; mice are generally shipped between four to six weeks of age with a maximum shipping age of ~nine weeks. Colony sizes do not generally support stringent age specifications for large volumes of mice; however custom orders and larger quantities of mice are easily arranged. Estimated ship dates for all orders provided within 48 hours of order placement. |
|---|---|
| Supply Notes |
Usually shipped between four and eight weeks of age. This strain is included in the Induced Mutant Resource Colony collection. |
| Licensing | See General Terms and Conditions below for Licensing and Use Restrictions |
| Control Information | View Control Information in Strain Details. |
General Terms and Conditions
View JAX® Mice & Services Conditions of Use.
For additional Licensing and Use Restrictions view the link(s) below:
- Strain(s) not available to companies or for-profit entities.
The Jackson Laboratory's Genotype Promise
The Jackson Laboratory has rigorous genetic quality control and mutant gene genotyping programs to ensure the genetic background of JAX® Mice strains as well as the genotypes of strains with identified molecular mutations. JAX® Mice strains are only made available to researchers after meeting our standards. However, the phenotype of each strain may not be fully characterized and/or captured in the strain data sheets. Therefore, we cannot guarantee a strain's phenotype will meet all expectations. To ensure that JAX® Mice will meet the needs of individual research projects or when requesting a strain that is new to your research, we suggest ordering and performing tests on a small number of mice to determine suitability for your particular project.Ordering and Purchasing Information
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