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- Description
- Phenotype
- Genes & alleles
- Genotyping
- Health & husbandry
- References
- Purchasing information
- Terms of Use
Description
Strain Information
Type Consomic; Additional information on Consomic Mice. Type Congenic; Additional information on Genetically Engineered Mutant Mice. Mating System Homozygote x Homozygote (Female x Male) Species laboratory mouse Background Strain C57BL/6J Donor Strain PWD/Ph H2 Haplotype b Generation ?+F3 (06-DEC-07) Appearance
black
Related Genotype: a/aDescription
This strain represents one of a panel of inter-species chromosome substitution (or consomic) strains (IC-ISS). Each strain carries a chromosome from the Mus musculus musculus wild-derived strain PWD/Ph introgressed into a Mus musculus domesticus C57BL/6J background. The two species are believed to have diverged 350,000 to one million years ago and exhibit multiple genetic and phenotypic differences. The strain set also includes a conplastic strain (mtPWD/Ph) created by sequential backcrossing of the donor female to the host male. A conplastic strain carries the mitochondrial genome of the donor strain. The IC-ISS strains represent a tool for dissection of quantitative trait loci.Development
Dr. Jiri Forejt from The Institute of Molecular Genetics, Prague, Czech Republic developed the C57BL/6J-Chr #PWD/Ph/ForeJ strain set by replacing individual chromosomes from the PWD/Ph donor strain into the C57BL/6J host strain using a marker-assisted series of backcrosses. The Chromosome 11 consomic is a partial consomic. Chr 11.2PWD/Ph indicates that the middle (m) portion of Chromosome 11 is from the PWD/Ph donor strain. The set was donated to The Jackson Laboratory in 2005.
Related Strains
B6/PWD Consomic Panel
007600 C57BL/6J-Chr 10.1PWD/Ph/ForeJ 006599 C57BL/6J-Chr 10.3PWD/Ph/ForeJ 005997 C57BL/6J-Chr 11.1PWD/Ph/ForeJ 006372 C57BL/6J-Chr 11.3PWD/Ph/ForeJ 005263 C57BL/6J-Chr 12PWD/Ph/ForeJ 005519 C57BL/6J-Chr 13PWD/Ph/ForeJ 005264 C57BL/6J-Chr 14PWD/Ph/ForeJ 005265 C57BL/6J-Chr 15PWD/Ph/ForeJ 005266 C57BL/6J-Chr 16PWD/Ph/ForeJ 005267 C57BL/6J-Chr 17PWD/Ph/ForeJ 005268 C57BL/6J-Chr 18PWD/Ph/ForeJ 005269 C57BL/6J-Chr 19PWD/Ph/ForeJ 005259 C57BL/6J-Chr 1PWD/Ph/ForeJ 005995 C57BL/6J-Chr 2PWD/Ph/ForeJ 005518 C57BL/6J-Chr 3PWD/Ph/ForeJ 006226 C57BL/6J-Chr 4PWD/Ph/ForeJ 005260 C57BL/6J-Chr 5PWD/Ph/ForeJ 005261 C57BL/6J-Chr 6PWD/Ph/ForeJ 005996 C57BL/6J-Chr 7PWD/Ph/ForeJ 006597 C57BL/6J-Chr 8PWD/Ph/ForeJ 005262 C57BL/6J-Chr 9PWD/Ph/ForeJ 005762 C57BL/6J-Chr X.1PWD/Ph/ForeJ 006598 C57BL/6J-Chr X.2PWD/Ph/ForeJ 006227 C57BL/6J-Chr X.3PWD/Ph/ForeJ 005270 C57BL/6J-Chr YPWD/Ph/ForeJ 005761 C57BL/6J-mtPWD/Ph/ForeJ View B6/PWD Consomic Panel (26 strains)
Additional Web Information
JAX® NOTES, Fall 2006; 503. C57BL/6J Chr#PWD/Ph/ForeJ Consomic Strain Panel Available from The Jackson Laboratory
Phenotype
Phenotype Information
This mouse can be used to support research in many areas including:
Research Tools
Genetics Research (Gene Mapping: Tools for QTL Mapping, Segregation and Linkage Analysis)
Genes & Alleles
Gene & Allele Information
Currently there are no related genes or alleles for this strain.Genotyping
Genotyping Information
This strain will not have a genotyping protocol or one is not currently available.
Helpful Links
Optimizing PCR Protocols
References
References
Selected Reference(s)
Gregorova S; Divina P; Storchova R; Trachtulec Z; Fotopulosova V; Svenson KL; Donahue LR; Paigen B; Forejt J. 2008. Mouse consomic strains: Exploiting genetic divergence between Mus m. musculus and Mus m. domesticus subspecies. Genome Res :. [PubMed: 18256238] [MGI Ref ID J:130871]
Health & husbandry
Health & Colony Maintenance Information
Animal Health Reports
Room Number AX11
Colony Maintenance
Mating System Homozygote x Homozygote (Female x Male) Diet Information LabDiet® 5K52/5K67
Purchasing information
Pricing, Supply Level & Notes, Controls, General Terms & Conditions
Pricing
| Pricing for USA, Canada and Mexico shipping destinations |
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Weeks of Age Price* Gender Genotypes Provided Individual Mouse Price $89.50 Female or Male Homozygous *Price(s) in US dollars ($)
Pairs /Price* Pair Genotype $179.00 Homozygous x Homozygous
Additional Supply Details
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| Pricing for International shipping destinations |
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Weeks of Age Price* Gender Genotypes Provided Individual Mouse Price $116.40 Female or Male Homozygous *Price(s) in US dollars ($)
Pairs /Price* Pair Genotype $232.70 Homozygous x Homozygous
Additional Supply Details
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Supply Details
| Standard Supply | Repository-Live. A collection of over 1000 strains maintained as live colonies. Individual colonies are sized to meet current customer demand. Delivery for orders of 10 mice or less ranges on average from one to eight weeks; mice are generally shipped between four to six weeks of age with a maximum shipping age of ~nine weeks. Colony sizes do not generally support stringent age specifications for large volumes of mice; however custom orders and larger quantities of mice are easily arranged. Estimated ship dates for all orders provided within 48 hours of order placement. |
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General Terms and Conditions
See Terms of Use
The Jackson Laboratory's Genotype Promise
The Jackson Laboratory has rigorous genetic quality control and mutant gene genotyping programs to ensure the genetic background of JAX® Mice strains as well as the genotypes of strains with identified molecular mutations. JAX® Mice strains are only made available to researchers after meeting our standards. However, the phenotype of each strain may not be fully characterized and/or captured in the strain data sheets. Therefore, we cannot guarantee a strain's phenotype will meet all expectations. To ensure that JAX® Mice will meet the needs of individual research projects or when requesting a strain that is new to your research, we suggest ordering and performing tests on a small number of mice to determine suitability for your particular project.Ordering and Purchasing Information
Purchasing Information
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Contact Information
Orders & Technical Support
Tel: 800.422.6423 or 207.288.5845
Fax: 207.288.6150
Technical Support Email Form
Terms of Use
Terms of Use
General Terms and Conditions
For Licensing and Use Restrictions view the link(s) below:
- Strain(s) not available to companies or for-profit entities.
Contact information
General inquiries
Contracts Administration
| phone: | 207-288-6470 |
| fax: | 207-288-6655 |
JAX® Mice & Services Conditions of Use
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