Strain Name:


Stock Number:


Order this mouse


Repository- Live

Use Restrictions Apply, see Terms of Use
Common Names: CMV-Cre;    
CMV-cre mice are useful for deletion of loxP-flanked genes in all tissues.


Strain Information

Type Congenic; Transgenic;
Additional information on Genetically Engineered and Mutant Mice.
Visit our online Nomenclature tutorial.
Additional information on Congenic nomenclature.
Mating SystemHomozygote x Hemizygote         (Female x Male)   25-APR-08
Specieslaboratory mouse
GenerationN10F10 (10-JUL-13)
Generation Definitions
Donating Investigator IMR Colony,   The Jackson Laboratory

In this transgenic strain, deletion of loxP-flanked genes occurs in all tissues, including germ cells. The cre gene in this strain is under the transcriptional control of a human cytomegalovirus minimal promoter and is likely to be expressed before implantation during early embryogenesis. It also appears that the cre gene is X-linked since transgene transmission through males is restricted to female offspring.

In an attempt to offer alleles on well-characterized or multiple genetic backgrounds, alleles are frequently moved to a genetic background different from that on which an allele was first characterized. This is the case for the strain above. It should be noted that the phenotype could vary from that originally described. We will modify the strain description if necessary as published results become available.

The cre gene used in this mutant mouse was modified by adding a nuclear localization signal and the human growth hormone gene providing splicing and polyadenylation signals. A construct containing cre coding sequence under the control of a human cytomegalovirus minimal promoter was introduced to BALB/cJ derived BALB/c-I embryonic stem (ES) cells. The resulting mice were backcrossed to the BALB/c background for 8 generations and then backcrossed to the C57BL/6J background for 10 generations.

Control Information

   000664 C57BL/6J
  Considerations for Choosing Controls

Related Strains

Strains carrying   Tg(CMV-cre)1Cgn allele
003465   BALB/c-Tg(CMV-cre)1Cgn/J
View Strains carrying   Tg(CMV-cre)1Cgn     (1 strain)

Strains carrying other alleles of cre
004337   129(Cg)-Foxg1tm1(cre)Skm/J
008569   129-Alpltm1(cre)Nagy/J
005989   129;FVB-Tg(PTH-cre)4167Slib/J
007179   129S.Cg-Tg(UBC-cre/ERT2)1Ejb/J
007915   129S.FVB-Tg(Amh-cre)8815Reb/J
003328   129S/Sv-Tg(Prm-cre)58Og/J
026200   129S1.Cg-Tg(Vsx2-cre)2690Chow/J
004302   129S1/Sv-Hprttm1(cre)Mnn/J
022137   129S4.Cg-Tg(Wnt1-cre)2Sor/J
003960   129S6-Tg(Prnp-GFP/cre)1Blw/J
008523   129S6.Cg-Tg(NPHS2-cre)295Lbh/BroJ
009587   B6(129S4)-Et(icre)1402Rdav/J
009588   B6(129S4)-Et(icre)1470Rdav/J
009589   B6(129S4)-Et(icre)1555Rdav/J
009586   B6(129S4)-Et(icre)754Rdav/J
012687   B6(129S4)-Tg(SYN1-icre/mRFP1)9934Rdav/J
010774   B6(Cg)-Calb2tm1(cre)Zjh/J
017562   B6(Cg)-Cd8atm1.1(cre)Koni/J
012704   B6(Cg)-Crhtm1(cre)Zjh/J
018448   B6(Cg)-Foxn1tm3(cre)Nrm/J
026801   B6(Cg)-Ins1tm1.1(cre)Thor/J
016223   B6(Cg)-Tg(Phox2b-cre)3Jke/J
016959   B6.129(Cg)-Foxp3tm4(YFP/cre)Ayr/J
023055   B6.129(Cg)-Krt12tm3(cre)Wwk/J
008320   B6.129-Leprtm2(cre)Rck/J
017526   B6.129-Nos1tm1(cre)Mgmj/J
005697   B6.129-Otx1tm4(cre)Asim/J
018938   B6.129-Tac2tm1.1(cre)Qima/J
017769   B6.129-Trpv1tm1(cre)Bbm/J
004146   B6.129-Tg(Pcp2-cre)2Mpin/J
008710   B6.129P2(129S4)-Hprttm10(Ple162-EGFP/cre)Ems/Mmjax
008877   B6.129P2(129S4)-Hprttm12(Ple177-EGFP/cre)Ems/Mmjax
009116   B6.129P2(129S4)-Hprttm16(Ple167-EGFP/cre)Ems/Mmjax
008709   B6.129P2(129S4)-Hprttm9(Ple178-EGFP/cre)Ems/Mmjax
006785   B6.129P2(C)-Cd19tm1(cre)Cgn/J
006084   B6.129P2(Cg)-Foxg1tm1(cre)Skm/J
010611   B6.129P2(Cg)-Ighg1tm1(IRES-cre)Cgn/J
007770   B6.129P2-Aicdatm1(cre)Mnz/J
004781   B6.129P2-Lyz2tm1(cre)Ifo/J
017320   B6.129P2-Pvalbtm1(cre)Arbr/J
017915   B6.129S(Cg)-Pgrtm1.1(cre)Shah/AndJ
013594   B6.129S-Atoh1tm5.1(Cre/PGR)Hzo/J
021794   B6.129S1(Cg)-Ascl3tm1.1(EGFP/cre)Ovi/J
024637   B6.129S1(SJL)-Nkx2-5tm2(cre)Rph/J
006600   B6.129S1-Mnx1tm4(cre)Tmj/J
005628   B6.129S2-Emx1tm1(cre)Krj/J
022510   B6.129S4-Gpr88tm1.1(cre/GFP)Rpa/J
017578   B6.129S4-Mcpt8tm1(cre)Lky/J
003755   B6.129S4-Meox2tm1(cre)Sor/J
007893   B6.129S4-Myf5tm3(cre)Sor/J
006878   B6.129S6-Taglntm2(cre)Yec/J
012839   B6.129X1(Cg)-Tnfrsf4tm2(cre)Nik/J
008712   B6.129X1-Twist2tm1.1(cre)Dor/J
020811   B6.C-Tg(Pgk1-cre)1Lni/CrsJ
023530   B6.Cg-Avptm1.1(cre)Hze/J
013590   B6.Cg-Braftm1Mmcm Ptentm1Hwu Tg(Tyr-cre/ERT2)13Bos/BosJ
006230   B6.Cg-Cebpatm1Dgt Tg(Mx1-cre)1Cgn/J
012358   B6.Cg-Pvalbtm1.1(cre)Aibs/J
005622   B6.Cg-Shhtm1(EGFP/cre)Cjt/J
022762   B6.Cg-Zfp335tm1.2Caw Emx1tm1(cre)Krj/J
017346   B6.Cg-Tg(A930038C07Rik-cre)1Aibs/J
006149   B6.Cg-Tg(ACTA1-cre)79Jme/J
003574   B6.Cg-Tg(Alb-cre)21Mgn/J
006881   B6.Cg-Tg(Aqp2-cre)1Dek/J
011104   B6.Cg-Tg(Atoh1-cre)1Bfri/J
008520   B6.Cg-Tg(CD2-cre)4Kio/J
009350   B6.Cg-Tg(CDX2-cre)101Erf/J
009352   B6.Cg-Tg(CDX2-cre*)189Erf/J
027310   B6.Cg-Tg(Camk2a-cre)2Szi/J
027400   B6.Cg-Tg(Camk2a-cre)3Szi/J
005359   B6.Cg-Tg(Camk2a-cre)T29-1Stl/J
022071   B6.Cg-Tg(Cd4-cre)1Cwi/BfluJ
012237   B6.Cg-Tg(Cdh16-cre)91Igr/J
006368   B6.Cg-Tg(Cr2-cre)3Cgn/J
006663   B6.Cg-Tg(Eno2-cre)39Jme/J
005069   B6.Cg-Tg(Fabp4-cre)1Rev/J
012712   B6.Cg-Tg(Fev-cre)1Esd/J
012849   B6.Cg-Tg(GFAP-cre/ERT2)505Fmv/J
012886   B6.Cg-Tg(Gfap-cre)73.12Mvs/J
024098   B6.Cg-Tg(Gfap-cre)77.6Mvs/2J
009642   B6.Cg-Tg(Gh1-cre)1Sac/J
024474   B6.Cg-Tg(Il9-cre)#Stck/J
003573   B6.Cg-Tg(Ins2-cre)25Mgn/J
008068   B6.Cg-Tg(Itgax-cre)1-1Reiz/J
008781   B6.Cg-Tg(Kap-cre)29066/2Sig/J
003802   B6.Cg-Tg(Lck-cre)548Jxm/J
006889   B6.Cg-Tg(Lck-cre)I540Jxm/J
012837   B6.Cg-Tg(Lck-icre)3779Nik/J
009643   B6.Cg-Tg(Lhb-cre)1Sac/J
008330   B6.Cg-Tg(Mc4r-cre)25Rck/J
003556   B6.Cg-Tg(Mx1-cre)1Cgn/J
007742   B6.Cg-Tg(Myh11-cre,-EGFP)2Mik/J
008205   B6.Cg-Tg(NPHS2-cre)295Lbh/J
003771   B6.Cg-Tg(Nes-cre)1Kln/J
010536   B6.Cg-Tg(Pcp2-cre)3555Jdhu/J
005975   B6.Cg-Tg(Plp1-cre/ERT)3Pop/J
008827   B6.Cg-Tg(Prdm1-cre)1Masu/J
005584   B6.Cg-Tg(Prrx1-cre)1Cjt/J
003967   B6.Cg-Tg(Rbp3-cre)528Jxm/J
021614   B6.Cg-Tg(S100A8-cre,-EGFP)1Ilw/J
008454   B6.Cg-Tg(Sox2-cre)1Amc/J
006361   B6.Cg-Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/J
003966   B6.Cg-Tg(Syn1-cre)671Jxm/J
017491   B6.Cg-Tg(Tagln-cre)1Her/J
004128   B6.Cg-Tg(Tek-cre)12Flv/J
008863   B6.Cg-Tg(Tek-cre)1Ywa/J
008601   B6.Cg-Tg(Th-cre)1Tmd/J
012328   B6.Cg-Tg(Tyr-cre/ERT2)13Bos/J
008085   B6.Cg-Tg(UBC-cre/ERT2)1Ejb/J
008610   B6.Cg-Tg(Vav1-cre)A2Kio/J
004586   B6.Cg-Tg(Vil-cre)997Gum/J
021504   B6.Cg-Tg(Vil1-cre)1000Gum/J
008735   B6.Cg-Tg(Wap-cre)11738Mam/JKnwJ
009614   B6.Cg-Tg(Wfs1-cre/ERT2)2Aibs/J
009107   B6.Cg-Tg(Wnt1-cre)11Rth Tg(Wnt1-GAL4)11Rth/J
022501   B6.Cg-Tg(Wnt1-cre)2Sor/J
006234   B6.Cg-Tg(tetO-cre)1Jaw/J
016832   B6.FVB(129)-Tg(Alb1-cre)1Dlr/J
005657   B6.FVB(129)-Tg(Myh6-cre/Esr1*)1Jmk/J
024688   B6.FVB(129S)-Tg(Pax6-GFP/cre)1Rilm/J
006475   B6.FVB(129S4)-Tg(Ckmm-cre)5Khn/J
006451   B6.FVB(129X1)-Tg(Sim1-cre)1Lowl/J
006333   B6.FVB(Cg)-Tg(Neurog3-cre)C1Able/J
014643   B6.FVB-Tg(CMA1-cre)6Thhe/J
006137   B6.FVB-Tg(Cdh5-cre)7Mlia/J
018980   B6.FVB-Tg(Ddx4-cre)1Dcas/KnwJ
003724   B6.FVB-Tg(EIIa-cre)C5379Lmgd/J
011069   B6.FVB-Tg(Gh1-cre)bKnmn/J
011038   B6.FVB-Tg(Myh6-cre)2182Mds/J
014647   B6.FVB-Tg(Pdx1-cre)6Tuv/J
010714   B6.FVB-Tg(Pomc-cre)1Lowl/J
022791   B6.FVB-Tg(Rorc-cre)1Litt/J
017535   B6.FVB-Tg(Slc32a1-cre)2.1Hzo/FrkJ
017490   B6.FVB-Tg(Stra8-icre)1Reb/LguJ
024670   B6.FVB-Tg(Ucp1-cre)1Evdr/J
003394   B6.FVB-Tg(Zp3-cre)3Mrt/J
006660   B6.SJL-Slc6a3tm1.1(cre)Bkmn/J
003552   B6129-Tg(Wap-cre)11738Mam/J
023161   B6129S-Tg(Foxp3-EGFP/cre)1aJbs/J
021025   B6;129-Gt(ROSA)26Sortm1(rtTA*M2)Jae Col1a1tm1(tetO-cre)Haho/J
010529   B6;129-Myf5tm1(cre)Mrc/J
010528   B6;129-Myf6tm2(cre)Mrc/J
017525   B6;129-Ntstm1(cre)Mgmj/J
005549   B6;129-Pax3tm1(cre)Joe/J
017968   B6;129-Tg(Cdh5-cre)1Spe/J
024860   B6;129-Tg(Drd1-cre)120Mxu/Mmjax
010988   B6;129P-Cyp11a1tm1(GFP/cre)Pzg/J
008529   B6;129P-Tg(Neurog1-cre/ERT2)1Good/J
012601   B6;129P2-Lyve1tm1.1(EGFP/cre)Cys/J
006668   B6;129P2-Omptm4(cre)Mom/MomJ
008069   B6;129P2-Pvalbtm1(cre)Arbr/J
012373   B6;129S-Hoxb1tm1(cre)Og/J
024234   B6;129S-Oxttm1.1(cre)Dolsn/J
023526   B6;129S-Rorbtm1.1(cre)Hze/J
023527   B6;129S-Slc17a7tm1.1(cre)Hze/J
023525   B6;129S-Snap25tm2.1(cre)Hze/J
021877   B6;129S-Tac1tm1.1(cre)Hze/J
021878   B6;129S-Tac2tm1.1(cre)Hze/J
017685   B6;129S-Wisp3tm1(cre)Mawa/J
007001   B6;129S-Tg(UBC-cre/ERT2)1Ejb/J
009388   B6;129S1-Osr2tm2(cre)Jian/J
012463   B6;129S4-Foxd1tm1(GFP/cre)Amc/J
011105   B6;129S4-Olig1tm1(cre)Rth/J
006410   B6;129S6-Chattm2(cre)Lowl/J
009616   B6;C3-Tg(A930038C07Rik-cre)4Aibs/J
012433   B6;C3-Tg(ACTA1-rtTA,tetO-cre)102Monk/J
008844   B6;C3-Tg(Ctgf-cre)2Aibs/J
008839   B6;C3-Tg(Cyp39a1-cre)1Aibs/J
009117   B6;C3-Tg(Cyp39a1-cre)7Aibs/J
008848   B6;C3-Tg(Mybpc1-cre)2Aibs/J
009111   B6;C3-Tg(Scnn1a-cre)1Aibs/J
009112   B6;C3-Tg(Scnn1a-cre)2Aibs/J
009613   B6;C3-Tg(Scnn1a-cre)3Aibs/J
009103   B6;C3-Tg(Wfs1-cre/ERT2)3Aibs/J
025806   B6;CBA-Tg(Gsx2-cre)1Kess/J
026555   B6;CBA-Tg(Lhx6-cre)1Kess/J
025807   B6;CBA-Tg(Sox10-cre)1Wdr/J
024507   B6;CBA-Tg(Tbx21-cre)1Dlc/J
017494   B6;D-Tg(Tshz3-GFP/cre)43Amc/J
024926   B6;D2-Tg(Fshr-cre)1Ldu/J
003466   B6;D2-Tg(Sycp1-cre)4Min/J
014160   B6;DBA-Tg(S100b-EGFP/cre/ERT2)22Amc/J
014159   B6;DBA-Tg(Tmem100-EGFP/cre/ERT2)30Amc/J
015855   B6;DBA-Tg(Upk3a-GFP/cre/ERT2)26Amc/J
010803   B6;FVB-Tg(Adipoq-cre)1Evdr/J
018422   B6;FVB-Tg(Aicda-cre)1Rcas/J
023748   B6;FVB-Tg(Aldh1l1-cre)JD1884Gsat/J
011087   B6;FVB-Tg(Crh-cre)1Kres/J
008533   B6;FVB-Tg(Cspg4-cre)1Akik/J
003734   B6;FVB-Tg(GZMB-cre)1Jcb/J
015850   B6;SJL-Pde6b+ Tg(Rho-icre)1Ck/Boc
004426   B6;SJL-Tg(Cga-cre)3Sac/J
003554   B6;SJL-Tg(Col2a1-cre)1Bhr/J
017738   B6;SJL-Tg(Foxl1-cre)1Khk/J
005249   B6;SJL-Tg(Krt1-15-cre/PGR)22Cot/J
019893   B6;SJL-Tg(Tex101-icre)2Lzj/J
007252   B6Ei.129S4-Tg(Prm-cre)58Og/EiJ
025524   B6J.B6N(Cg)-Cx3cr1tm1.1(cre)Jung/J
018956   B6N.129P2(B6)-Lyz2tm1(cre)Ifo/J
018958   B6N.129P2-Cd19tm1(cre)Cgn/J
021077   B6N.129S1-Mrgprb4tm3(cre)And/J
018957   B6N.129S6(B6)-Chattm2(cre)Lowl/J
017911   B6N.129S6(Cg)-Esr1tm1.1(cre)And/J
019013   B6N.129S6(Cg)-Gt(ROSA)26Sortm2(EGFP/cre)Alj/J
018974   B6N.B6-Tg(Nr4a1-EGFP/cre)820Khog/J
019021   B6N.Cg-Ccktm1.1(cre)Zjh/J
019022   B6N.Cg-Gad2tm2(cre)Zjh/J
018973   B6N.Cg-Ssttm2.1(cre)Zjh/J
018961   B6N.Cg-Tg(Alb-cre)21Mgn/J
018966   B6N.Cg-Tg(Camk2a-cre)T29-1Stl/J
018965   B6N.Cg-Tg(Fabp4-cre)1Rev/J
017310   B6N.Cg-Tg(Hsd17b1-icre/ERT2)3Casa/J
018960   B6N.Cg-Tg(Ins2-cre)25Mgn/J
018967   B6N.Cg-Tg(Itgax-cre)1-1Reiz/J
018964   B6N.Cg-Tg(KRT14-cre)1Amc/J
019103   B6N.Cg-Tg(Nes-cre)1Kln/CjDswJ
014094   B6N.Cg-Tg(Sox2-cre)1Amc/J
018968   B6N.Cg-Tg(Vav1-cre)A2Kio/J
018963   B6N.Cg-Tg(Vil-cre)997Gum/J
018972   B6N.FVB(B6)-Tg(Myh6-cre)2182Mds/J
019099   B6N.FVB-Tg(ACTB-cre)2Mrt/CjDswJ
019509   B6N.FVB-Tg(BGLAP-cre)1Clem/J
023047   B6N.FVB-Tg(Dmp1-cre)1Jqfe/BwdJ
017927   B6N.FVB-Tg(Mpz-cre)26Mes/J
012641   BALB/c-Tg(S100a4-cre)1Egn/YunkJ
010612   C.129P2(Cg)-Ighg1tm1(IRES-cre)Cgn/J
017353   C.129S4(B6)-Il13tm1(YFP/cre)Lky/J
017582   C.129S4(B6)-Mcpt8tm1(cre)Lky/J
004126   C.Cg-Cd19tm1(cre)Cgn Ighb/J
005673   C.Cg-Tg(Mx1-cre)1Cgn/J
006244   C.Cg-Tg(tetO-cre)1Jaw/J
009155   C57BL/6-Cldn6tm1(cre)Dkwu/J
017557   C57BL/6-Tg(BEST1-cre)1Jdun/J
027406   C57BL/6-Tg(CD2-cre)1Lov/J
016097   C57BL/6-Tg(Car1-cre)5Flt/J
011086   C57BL/6-Tg(Cck-cre)CKres/J
008766   C57BL/6-Tg(Cd8a-cre)1Itan/J
026828   C57BL/6-Tg(Cpa3-cre)4Glli/J
006474   C57BL/6-Tg(Grik4-cre)G32-4Stl/J
008314   C57BL/6-Tg(HBB-cre)12Kpe/J
008870   C57BL/6-Tg(Hspa2-cre)1Eddy/J
016261   C57BL/6-Tg(Nes-cre/ERT2)KEisc/J
012906   C57BL/6-Tg(Nes-cre/Esr1*)1Kuan/J
027205   C57BL/6-Tg(Nms-icre)20Ywa/J
016617   C57BL/6-Tg(Nr4a1-EGFP/cre)820Khog/J
020287   C57BL/6-Tg(Pbsn-cre/Esr1*)14Abch/J
013148   C57BL/6-Tg(Pdgfra-cre)1Clc/J
008535   C57BL/6-Tg(Pf4-cre)Q3Rsko/J
024034   C57BL/6-Tg(Pmch-cre)1Rck/J
016583   C57BL/6-Tg(Slc6a3-icre/ERT2)2Gloss/J
006888   C57BL/6-Tg(Zp3-cre)1Gwh/J
003651   C57BL/6-Tg(Zp3-cre)93Knw/J
021119   C57BL/6J-Tg(Dlx2-cre,-mCherry)4Grsr/GrsrJ
021423   C57BL/6J-Tg(Dlx2-cre,-mCherry)9Grsr/GrsrJ
007567   C57BL/6J-Tg(Itgax-cre,-EGFP)4097Ach/J
018895   C57BL/6J-Tg(Krt6,-cre,-Cerulean)1Grsr/Grsr
018896   C57BL/6J-Tg(Krt6,-cre,-Cerulean)2Grsr/Grsr
018898   C57BL/6J-Tg(Krt6,-cre,-Cerulean)4Grsr/Grsr
018899   C57BL/6J-Tg(Krt6,-cre,-Cerulean)5Grsr/Grsr
021582   C57BL/6J-Tg(Mchr1-cre)1Emf/J
008661   C57BL/6J-Tg(Nkx2-1-cre)2Sand/J
022883   C57BL/6J-Tg(Six6-cre)3Grsr/GrsrJ
022887   C57BL/6J-Tg(Six6-cre)7Grsr/GrsrJ
018754   C57BL/6J-Tg(Tbx22,-cre,-mCherry)1Grsr/GrsrJ
019363   C57BL/6J-Tg(Trp63,-cre,-Cerulean)10Grsr/Grsr
018792   C57BL/6J-Tg(Trp63,-cre,-Cerulean)4Grsr/GrsrJ
003650   C57BL/6J-Tg(Zp3-cre)82Knw/KnwJ
018151   C57BL/6N-Krt17tm1(cre,Cerulean)Murr/GrsrJ
023014   C57BL/6N-Tg(Calcrl,cre)4688Nkza/J
012686   C57BL/6N-Tg(Ppp1r2-cre)4127Nkza/J
016582   C57BL/6N-Tg(Slc32a1-icre/ERT2)3Gloss/J
026861   D2.129P2(B6)-Lyz2tm1(cre)Ifo/SjJ
026858   D2.129S4(B6)-Meox2tm1(cre)Sor/SjJ
026266   D2.B6-Tg(Zp3-cre)93Knw/SjJ
026852   D2.Cg-Tg(Gfap-cre)73.12Mvs/SjJ
024701   D2.Cg-Tg(Plp1-cre/ERT)3Pop/SjJ
026859   D2.Cg-Tg(Sox2-cre)1Amc/SjJ
026857   D2.FVB-Tg(GFAP-cre)25Mes/SjJ
026860   D2.FVB-Tg(Tek-cre)2352Rwng/SjJ
016833   FVB(Cg)-Tg(Alb1-cre)1Dlr/J
012929   FVB(Cg)-Tg(Dhh-cre)1Mejr/J
011034   FVB(Cg)-Tg(Ghrhr-cre)3242Lsk/J
006405   FVB-Tg(Ckmm-cre)5Khn/J
021024   FVB-Tg(Csf1r-icre)1Jwp/J
006954   FVB-Tg(Ddx4-cre)1Dcas/J
004600   FVB-Tg(GFAP-cre)25Mes/J
011037   FVB-Tg(Myh6-cre)2182Mds/J
006364   FVB-Tg(Nr5a1-cre)2Lowl/J
008537   FVB-Tg(Tek-cre)2352Rwng/J
019382   FVB.Cg-Myh9tm1.1Gac Tg(NPHS2-cre)295Lbh/Mmjax
014140   FVB.Cg-Myod1tm2.1(icre)Glh/J
006139   FVB.Cg-Tg(ACTA1-cre)79Jme/J
006297   FVB.Cg-Tg(Eno2-cre)39Jme/J
018394   FVB.Cg-Tg(KRT5-cre/ERT2)2Ipc/JeldJ
008244   FVB.Cg-Tg(tetO-cre)1Jaw/J
003376   FVB/N-Tg(ACTB-cre)2Mrt/J
024384   FVB/N-Tg(AMELX-cre)A1Kul/J
003314   FVB/N-Tg(EIIa-cre)C5379Lmgd/J
025062   FVB/N-Tg(Figla-EGFP,-icre)ZP3Dean/Mmjax
017928   FVB/N-Tg(Mpz-cre)26Mes/J
025066   FVB/N-Tg(Mylpf-cre)3Kraj/Mmjax
006143   FVB/N-Tg(Thy1-cre)1Vln/J
003377   FVB/N-Tg(Zp3-cre)3Mrt/J
023325   FVB;B6-Tg(Pbsn-cre)20Fwan/J
019096   NOD.129P2(B6)-Lyz2tm1(cre)Ifo/NadlJ
023806   NOD.129P2(Cg)-Cd19tm1(cre)Cgn/J
013233   NOD.B6-Tg(Itgax-cre,-EGFP)4097Ach/J
013234   NOD.Cg-Tg(Cd4-cre)1Cwi/2AchJ
023972   NOD.Cg-Tg(Ins2-cre/ERT)1Dam/SbwJ
023203   NOD.Cg-Tg(Itgax-cre)1-1Reiz/PesaJ
005732   NOD.Cg-Tg(Lck-cre)548Jxm/AchJ
023973   NOD.Cg-Tg(Neurog3-cre)1Dam/SbwJ
013251   NOD.FVB-Tg(EIIa-cre)C5379Lmgd/J
008694   NOD/ShiLt-Tg(Foxp3-EGFP/cre)1cJbs/J
004986   NOD/ShiLt-Tg(Ins2-cre)3Lt/LtJ
003855   NOD/ShiLt-Tg(Ins2-cre)5Lt/LtJ
004987   NOD/ShiLt-Tg(Ins2-cre)6Lt/LtJ
012899   STOCK Agrptm1(cre)Lowl/J
026229   STOCK Akap12tm1Ihg Rb1tm2Brn Tg(Pbsn-cre)4Prb/J
012706   STOCK Ccktm1.1(cre)Zjh/J
010910   STOCK Corttm1(cre)Zjh/J
007916   STOCK En1tm2(cre)Wrst/J
008464   STOCK Foxa2tm2.1(cre/Esr1*)Moon/J
010802   STOCK Gad2tm2(cre)Zjh/J
018903   STOCK Gt(ROSA)26Sortm2(EGFP/cre)Alj/J
023407   STOCK HhatTg(TFAP2A-cre)1Will/J
008876   STOCK Hprttm11(Ple176-EGFP/cre)Ems/Mmjax
016879   STOCK Il17atm1.1(icre)Stck/J
024242   STOCK Isl1tm1(cre)Sev/J
018976   STOCK Kdrtm1(cre)Sato/J
017701   STOCK Kiss1tm1.1(cre/EGFP)Stei/J
007022   STOCK Mnx1tm4(cre)Tmj Tg(SMN2)89Ahmb Smn1tm1Msd Tg(SMN2*delta7)4299Ahmb/J
004192   STOCK Mttptm2Sgy Ldlrtm1Her Apobtm2Sgy Tg(Mx1-cre)1Cgn/J
023342   STOCK Myf5tm1(cre/Esr1*)Trdo/J
024713   STOCK Myl1tm1(cre)Sjb/J
014180   STOCK Myocdtm1(cre)Jomm/J
006953   STOCK Notch1tm3(cre)Rko/J
006677   STOCK Olfr151tm28(cre)Mom/MomJ
011103   STOCK Olig2tm2(TVA,cre)Rth/J
010530   STOCK Pax7tm1(cre)Mrc/J
016963   STOCK Slc17a6tm2(cre)Lowl/J
016962   STOCK Slc32a1tm2(cre)Lowl/J
013044   STOCK Ssttm2.1(cre)Zjh/J
012719   STOCK Tgfb3tm1(cre)Vk/J
012620   STOCK Trp53tm1Brd Brca1tm1Aash Tg(LGB-cre)74Acl/J
010908   STOCK Viptm1(cre)Zjh/J
010911   STOCK Wt1tm1(EGFP/cre)Wtp/J
009615   STOCK Tg(Cartpt-cre)1Aibs/J
017336   STOCK Tg(Cd4-cre)1Cwi/BfluJ
005105   STOCK Tg(Chx10-EGFP/cre,-ALPP)2Clc/J
008852   STOCK Tg(En2-cre)22Alj/J
005938   STOCK Tg(Eno2-cre)39Jme/J
011062   STOCK Tg(Gdf9-cre)5092Coo/J
012841   STOCK Tg(Ggt1-cre)M3Egn/J
021207   STOCK Tg(Gnrh1-cre)1Dlc/J
017981   STOCK Tg(Hoxb6-cre)#Mku/J
004692   STOCK Tg(Hoxb7-cre)13Amc/J
014600   STOCK Tg(I12b-cre/ERT2,-ALPP)37Fsh/J
008122   STOCK Tg(Ins2-cre/ERT)1Dam/J
004782   STOCK Tg(KRT14-cre)1Amc/J
005107   STOCK Tg(KRT14-cre/ERT)20Efu/J
008582   STOCK Tg(Kcnc2-Cre)K128Stl/LetJ
023426   STOCK Tg(Kiss1-cre)J2-4Cfe/J
017836   STOCK Tg(LGB-cre)74Acl/J
003551   STOCK Tg(MMTV-cre)1Mam/J
003553   STOCK Tg(MMTV-cre)4Mam/J
002527   STOCK Tg(Mx1-cre)1Cgn/J
009074   STOCK Tg(Myh6-cre)1Jmk/J
005650   STOCK Tg(Myh6-cre/Esr1*)1Jmk/J
009102   STOCK Tg(Nefh-cre)12Kul/J
002858   STOCK Tg(Nes-cre)1Wme/J
002859   STOCK Tg(Nes-cre)2Wme/J
012859   STOCK Tg(Neurog1-cre)1Jejo/J
005667   STOCK Tg(Neurog3-cre)C1Able/J
008119   STOCK Tg(Neurog3-cre/Esr1*)1Dam/J
012462   STOCK Tg(Nr5a1-cre)7Lowl/J
014158   STOCK Tg(Pax4-cre)1Dam/J
024578   STOCK Tg(Pax6-GFP/cre)1Rilm/J
006207   STOCK Tg(Pcp2-cre)1Amc/J
014099   STOCK Tg(Pmch-cre)1Lowl/J
005965   STOCK Tg(Pomc1-cre)16Lowl/J
012452   STOCK Tg(Rr5-GFP/cre)1Sapc/J
006395   STOCK Tg(Sim1-cre)1Lowl/J
009606   STOCK Tg(Six2-EGFP/cre)1Amc/J
019755   STOCK Tg(Six3-cre)69Frty/GcoJ
018147   STOCK Tg(Slc17a8-icre)1Edw/SealJ
012586   STOCK Tg(Slc1a3-cre/ERT)1Nat/J
004783   STOCK Tg(Sox2-cre)1Amc/J
008208   STOCK Tg(Stra8-icre)1Reb/J
016236   STOCK Tg(TCF/Lef1-cre/ERT2)1Dje/J
004746   STOCK Tg(Tagln-cre)1Her/J
012708   STOCK Tg(Thy1-cre/ERT2,-EYFP)HGfng/PyngJ
024240   STOCK Tg(Tnnt2-cre)5Blh/JiaoJ
016584   STOCK Tg(Tph2-icre/ERT2)6Gloss/J
003829   STOCK Tg(Wnt1-cre)11Rth Tg(Wnt1-GAL4)11Rth/J
008851   STOCK Tg(Wnt1-cre/ERT)1Alj/J
018281   STOCK Tg(Wnt7a-EGFP/cre)#Bhr/Mmjax
008199   STOCK Tg(dlx6a-cre)1Mekk/J
002471   STOCK Tg(hCMV-cre)140Sau/J
023724   STOCK Tg(mI56i-cre,EGFP)1Kc/J
006224   STOCK Tg(tetO-cre)1Jaw/J
View Strains carrying other alleles of cre     (401 strains)

Strains carrying other alleles of CMV
017456   B6(C)-Tg(CAG-mCherry,-GAL4)769Gsn/J
017457   B6(C)-Tg(CAG-mCherry,-GAL4)774Gsn/J
021469   B6(D2)-Tg(CAG-GFP,-Uprt)985Cdoe/J
018439   B6.129S6-Tg(CAG-Bgeo,-SMN2)E9Dscd/J
025855   B6.Cg-Ptprca Lag3tm1Doi Tg(CAG-luc,-GFP)L2G85Chco Thy1a/J
016197   B6.Cg-Tg(CAG-OTC/CAT)4033Prab/J
018021   B6.Cg-Tg(CAG-Tfb1m)AGsha/J
016882   B6.Cg-Tg(CMV-CASP3)14Edge/J
016908   B6.Cg-Tg(CMV-CASP3)17Edge/J
008300   B6.Cg-Tg(CMV-Klc1)73Gsn/J
008301   B6.Cg-Tg(CMV-Klc1)90Gsn/J
007237   B6.Cg-Tg(CMV-Serpine1)1Dgi/J
025854   B6.FVB-Ptprca Tg(CAG-luc,-GFP)L2G85Chco Thy1a/J
018056   B6.FVB-Tg(CAG-boNT/B,-EGFP)U75-56Fwp/J
017524   B6;129-Tg(CMV-Bgeo,-WGA,-ALPP)1Mgmj/J
014605   B6;129S-Tg(CMV-BBS1)6Vcs/J
017954   B6;C-Tg(CAG-Epha4/Efna5,-mCherry)1Slp/J
016532   B6N.FVB(Cg)-Tg(CAG-rtTA3)4288Slowe/J
010545   C.FVB-Tg(CAG-luc,-GFP)L2G85Chco/FathJ
014564   C57BL/6-Tg(CMV-Tsc2*)1Arbi/KlanJ
006362   C57BL/6J-Tg(CMV-Cox8a/EYFP)17J/J
010548   D1.FVB(Cg)-Tg(CAG-luc,-GFP)L2G85Chco/FathJ
018543   FVB-Tg(CAG-cat,-Twist1)1Dbsp/J
008450   FVB-Tg(CAG-luc,-GFP)L2G85Chco/J
006439   FVB-Tg(tetO/CMV-KRAS*G12C)9.1Msmi/J
018393   FVB/N-Tg(CAG-EGFP,TGFB1*)C8Kul/J
025664   FVB/N-Tg(CMV-Plaur*)19Lbh/J
004375   FVB/N-Tg(tetO-Kras2)12Hev/J
004644   NOD.Cg Prkdcscid-Tg(CSF2)2Ygy Tg(IL3)1Ygy Tg(KITLG)3Ygy/YgyJ
013062   NOD.Cg-Prkdcscid Il2rgtm1Wjl Tg(CMV-IL3,CSF2,KITLG)1Eav/MloySzJ
011066   NOD.Cg-Prkdcscid Il2rgtm1Wjl Tg(CSF2)2Ygy Tg(IL3)1Ygy Tg(KITLG)3Ygy/YgyJGckRolyJ
024099   NOD.Cg-Rag1tm1Mom Il2rgtm1Wjl Tg(CMV-IL3,CSF2,KITLG)1Eav/J
010542   NOD.FVB-Tg(CAG-luc,-GFP)L2G85Chco/FathJ
014092   STOCK Tg(ACTB-tTA2,-MAPT/lacZ)1Luo/J
013753   STOCK Tg(CAG-KikGR)33Hadj/J
013754   STOCK Tg(CAG-KikGR)75Hadj/J
019082   STOCK Tg(CMV-GFP,-BBS4)4T25Vcs/J
002471   STOCK Tg(hCMV-cre)140Sau/J
014093   STOCK Tg(tetO-CHRM3*)1Blr/J
View Strains carrying other alleles of CMV     (39 strains)

Additional Web Information

Introduction to Cre-lox technology


Phenotype Information

View Research Applications

Research Applications
This mouse can be used to support research in many areas including:

Research Tools
Cre-lox System
      Cre Recombinase Expression
      Cre Recombinase Expression: Germline/Embryonic Expression
Developmental Biology Research
      Cre-lox System
Genetics Research
      Mutagenesis and Transgenesis
      Mutagenesis and Transgenesis: Cre-lox System
      Tissue/Cell Markers
      Tissue/Cell Markers: Cre-lox System

cre related

Research Tools
Cre-lox System
Genetics Research
      Mutagenesis and Transgenesis
      Mutagenesis and Transgenesis: Cre-lox System

Genes & Alleles

Gene & Allele Information provided by MGI

Allele Symbol Tg(CMV-cre)1Cgn
Allele Name transgene insertion 1, University of Cologne
Allele Type Transgenic (cre- or Flp-expressing)
Common Name(s) CMV-Cre; CMV:Cre; Cre deleter; DCre; TgN(CMV-Cre)#Cgn; deleter; ubi-cre;
Mutation Made ByDr. Frieder Schwenk,   University of Cologne
Strain of OriginBALB/cJ
ES Cell Line NameBALB/c-I
ES Cell Line StrainBALB/cJ
Site of Expressionwidespread expression, including germline
Expressed Gene cre, cre recombinase, bacteriophage P1
Cre recombinase is an enzyme derived from the bacteriophage P1 that specifically recognizes loxP sites. Cre has been shown to effectively mediate the excision of DNA located between loxP sites. After the excision event, the DNA ends recombine leaving a single loxP site in place of the intervening sequence.
Promoter CMV, cytomegalovirus, human
Driver Note CMV
General Note Homozygous transgenic mice are viable and fertile. The transgene appears to be X-linked since transgene transmission through males is restricted to female offspring.

In transgenic mice, in conjunction with a transgene carrying a loxP-flanked gene, deletion of the loxP-flanked gene occurs in all tissues including germ cells.

Molecular Note This transgene expresses Cre recombinase under the control of a human cytomegalovirus (CMV) promoter, active in most cells and tissues. [MGI Ref ID J:75204]


Genotyping Information

Genotyping Protocols

Generic Cre Melt Curve Analysis, MELT
Generic Cre Melt Curve Analysis, Probe
Generic Cre Quantitative PCR, QPCR
Generic Cre, Standard PCR

Helpful Links

Genotyping resources and troubleshooting


References provided by MGI

Selected Reference(s)

Schwenk F; Baron U; Rajewsky K. 1995. A cre-transgenic mouse strain for the ubiquitous deletion of loxP-flanked gene segments including deletion in germ cells. Nucleic Acids Res 23(24):5080-1. [PubMed: 8559668]  [MGI Ref ID J:75204]

Additional References

Tg(CMV-cre)1Cgn related

Abraira VE; Del Rio T; Tucker AF; Slonimsky J; Keirnes HL; Goodrich LV. 2008. Cross-repressive interactions between Lrig3 and netrin 1 shape the architecture of the inner ear. Development 135(24):4091-9. [PubMed: 19004851]  [MGI Ref ID J:142510]

Adams DJ; Head GA; Markus MA; Lovicu FJ; van der Weyden L; Kontgen F; Arends MJ; Thiru S; Mayorov DN; Morris BJ. 2006. Renin enhancer is critical for control of renin gene expression and cardiovascular function. J Biol Chem 281(42):31753-61. [PubMed: 16895910]  [MGI Ref ID J:117294]

Akiyama R; Kawakami H; Taketo MM; Evans SM; Wada N; Petryk A; Kawakami Y. 2014. Distinct populations within Isl1 lineages contribute to appendicular and facial skeletogenesis through the beta-catenin pathway. Dev Biol 387(1):37-48. [PubMed: 24424161]  [MGI Ref ID J:207610]

Albertson TM; Ogawa M; Bugni JM; Hays LE; Chen Y; Wang Y; Treuting PM; Heddle JA; Goldsby RE; Preston BD. 2009. DNA polymerase epsilon and delta proofreading suppress discrete mutator and cancer phenotypes in mice. Proc Natl Acad Sci U S A 106(40):17101-4. [PubMed: 19805137]  [MGI Ref ID J:153684]

Albiston AL; Fernando RN; Yeatman HR; Burns P; Ng L; Daswani D; Diwakarla S; Pham V; Chai SY. 2009. Gene knockout of insulin-regulated aminopeptidase: Loss of the specific binding site for angiotensin IV and age-related deficit in spatial memory. Neurobiol Learn Mem :. [PubMed: 19660563]  [MGI Ref ID J:154386]

Alpy F; Jivkov I; Sorokin L; Klein A; Arnold C; Huss Y; Kedinger M; Simon-Assmann P; Lefebvre O. 2005. Generation of a conditionally null allele of the laminin alpha1 gene. Genesis 43(2):59-70. [PubMed: 16100707]  [MGI Ref ID J:102740]

An W; Han JS; Schrum CM; Maitra A; Koentgen F; Boeke JD. 2008. Conditional activation of a single-copy L1 transgene in mice by Cre. Genesis 46(7):373-83. [PubMed: 18615728]  [MGI Ref ID J:138548]

Andreadi C; Cheung LK; Giblett S; Patel B; Jin H; Mercer K; Kamata T; Lee P; Williams A; McMahon M; Marais R; Pritchard C. 2012. The intermediate-activity L597VBRAF mutant acts as an epistatic modifier of oncogenic RAS by enhancing signaling through the RAF/MEK/ERK pathway. Genes Dev 26(17):1945-58. [PubMed: 22892241]  [MGI Ref ID J:187371]

Ansel KM; Pastor WA; Rath N; Lapan AD; Glasmacher E; Wolf C; Smith LC; Papadopoulou N; Lamperti ED; Tahiliani M; Ellwart JW; Shi Y; Kremmer E; Rao A; Heissmeyer V. 2008. Mouse Eri1 interacts with the ribosome and catalyzes 5.8S rRNA processing. Nat Struct Mol Biol 15(5):523-30. [PubMed: 18438418]  [MGI Ref ID J:146701]

Antonson P; Omoto Y; Humire P; Gustafsson JA. 2012. Generation of ERalpha-floxed and knockout mice using the Cre/LoxP system. Biochem Biophys Res Commun 424(4):710-6. [PubMed: 22800760]  [MGI Ref ID J:186230]

Araki T; Chan G; Newbigging S; Morikawa L; Bronson RT; Neel BG. 2009. Noonan syndrome cardiac defects are caused by PTPN11 acting in endocardium to enhance endocardial-mesenchymal transformation. Proc Natl Acad Sci U S A 106(12):4736-41. [PubMed: 19251646]  [MGI Ref ID J:147154]

Arandjelovic S; McKenney KR; Leming SS; Mowen KA. 2012. ATP induces protein arginine deiminase 2-dependent citrullination in mast cells through the P2X7 purinergic receptor. J Immunol 189(8):4112-22. [PubMed: 22984079]  [MGI Ref ID J:190651]

Arnon TI; Xu Y; Lo C; Pham T; An J; Coughlin S; Dorn GW; Cyster JG. 2011. GRK2-dependent S1PR1 desensitization is required for lymphocytes to overcome their attraction to blood. Science 333(6051):1898-903. [PubMed: 21960637]  [MGI Ref ID J:176118]

Audero E; Coppi E; Mlinar B; Rossetti T; Caprioli A; Banchaabouchi MA; Corradetti R; Gross C. 2008. Sporadic autonomic dysregulation and death associated with excessive serotonin autoinhibition. Science 321(5885):130-3. [PubMed: 18599790]  [MGI Ref ID J:137439]

Augustin I; Gross J; Baumann D; Korn C; Kerr G; Grigoryan T; Mauch C; Birchmeier W; Boutros M. 2013. Loss of epidermal Evi/Wls results in a phenotype resembling psoriasiform dermatitis. J Exp Med 210(9):1761-77. [PubMed: 23918954]  [MGI Ref ID J:202499]

Bacaj T; Ahmad M; Jurado S; Malenka RC; Sudhof TC. 2015. Synaptic Function of Rab11Fip5: Selective Requirement for Hippocampal Long-Term Depression. J Neurosci 35(19):7460-74. [PubMed: 25972173]  [MGI Ref ID J:221637]

Bagheri-Fam S; Sim H; Bernard P; Jayakody I; Taketo MM; Scherer G; Harley VR. 2008. Loss of Fgfr2 leads to partial XY sex reversal. Dev Biol 314(1):71-83. [PubMed: 18155190]  [MGI Ref ID J:130928]

Baldock PA; Sainsbury A; Couzens M; Enriquez RF; Thomas GP; Gardiner EM; Herzog H. 2002. Hypothalamic Y2 receptors regulate bone formation. J Clin Invest 109(7):915-21. [PubMed: 11927618]  [MGI Ref ID J:97455]

Barlow JL; Bellosi A; Hardman CS; Drynan LF; Wong SH; Cruickshank JP; McKenzie AN. 2012. Innate IL-13-producing nuocytes arise during allergic lung inflammation and contribute to airways hyperreactivity. J Allergy Clin Immunol 129(1):191-8.e1-4. [PubMed: 22079492]  [MGI Ref ID J:181037]

Barriere C; Santamaria D; Cerqueira A; Galan J; Martin A; Ortega S; Malumbres M; Dubus P; Barbacid M. 2007. Mice thrive without Cdk4 and Cdk2. Mol Oncol 1(1):72-83. [PubMed: 19383288]  [MGI Ref ID J:125217]

Bartoli M; Gicquel E; Barrault L; Soheili T; Malissen M; Malissen B; Vincent-Lacaze N; Perez N; Udd B; Danos O; Richard I. 2008. Mannosidase I inhibition rescues the human alpha-sarcoglycan R77C recurrent mutation. Hum Mol Genet 17(9):1214-21. [PubMed: 18252745]  [MGI Ref ID J:133929]

Bellenchi GC; Gurniak CB; Perlas E; Middei S; Ammassari-Teule M; Witke W. 2007. N-cofilin is associated with neuronal migration disorders and cell cycle control in the cerebral cortex. Genes Dev 21(18):2347-57. [PubMed: 17875668]  [MGI Ref ID J:125317]

Bendelac A. 2011. Direct Data Submission 2011/08/15 MGI Direct Data Submission :.  [MGI Ref ID J:174415]

Bennett MK; Kulaga HM; Reed RR. 2010. Odor-evoked gene regulation and visualization in olfactory receptor neurons. Mol Cell Neurosci 43(4):353-62. [PubMed: 20080187]  [MGI Ref ID J:158375]

Beppu K; Kosai Y; Kido MA; Akimoto N; Mori Y; Kojima Y; Fujita K; Okuno Y; Yamakawa Y; Ifuku M; Shinagawa R; Nabekura J; Sprengel R; Noda M. 2013. Expression, subunit composition, and function of AMPA-type glutamate receptors are changed in activated microglia; possible contribution of GluA2 (GluR-B)-deficiency under pathological conditions. Glia 61(6):881-91. [PubMed: 23468421]  [MGI Ref ID J:195043]

Berahovich RD; Zabel BA; Penfold ME; Lewen S; Wang Y; Miao Z; Gan L; Pereda J; Dias J; Slukvin II; McGrath KE; Jaen JC; Schall TJ. 2010. CXCR7 protein is not expressed on human or mouse leukocytes. J Immunol 185(9):5130-9. [PubMed: 20889540]  [MGI Ref ID J:165184]

Bereshchenko O; Mancini E; Luciani L; Gambardella A; Riccardi C; Nerlov C. 2012. Pontin is essential for murine hematopoietic stem cell survival. Haematologica 97(9):1291-4. [PubMed: 22371176]  [MGI Ref ID J:220926]

Berger S; Wolfer DP; Selbach O; Alter H; Erdmann G; Reichardt HM; Chepkova AN; Welzl H; Haas HL; Lipp HP; Schutz G. 2006. Loss of the limbic mineralocorticoid receptor impairs behavioral plasticity. Proc Natl Acad Sci U S A 103(1):195-200. [PubMed: 16368758]  [MGI Ref ID J:104549]

Bertocchi I; Oberto A; Longo A; Mele P; Sabetta M; Bartolomucci A; Palanza P; Sprengel R; Eva C. 2011. Regulatory functions of limbic Y1 receptors in body weight and anxiety uncovered by conditional knockout and maternal care. Proc Natl Acad Sci U S A 108(48):19395-400. [PubMed: 22084082]  [MGI Ref ID J:180396]

Bertrand MJ; Kenchappa RS; Andrieu D; Leclercq-Smekens M; Nguyen HN; Carter BD; Muscatelli F; Barker PA; De Backer O. 2008. NRAGE, a p75NTR adaptor protein, is required for developmental apoptosis in vivo. Cell Death Differ 15(12):1921-9. [PubMed: 18772898]  [MGI Ref ID J:157604]

Billich A; Baumruker T; Beerli C; Bigaud M; Bruns C; Calzascia T; Isken A; Kinzel B; Loetscher E; Metzler B; Mueller M; Nuesslein-Hildesheim B; Kleylein-Sohn B. 2013. Partial deficiency of sphingosine-1-phosphate lyase confers protection in experimental autoimmune encephalomyelitis. PLoS One 8(3):e59630. [PubMed: 23544080]  [MGI Ref ID J:199525]

Billig GM; Pal B; Fidzinski P; Jentsch TJ. 2011. Ca(2)-activated Cl currents are dispensable for olfaction. Nat Neurosci 14(6):763-9. [PubMed: 21516098]  [MGI Ref ID J:173937]

Bird A. 2011. Direct Data Submission 2011/02/25 MGI Direct Data Submission :.  [MGI Ref ID J:168822]

Bleul CC; Corbeaux T; Reuter A; Fisch P; Monting JS; Boehm T. 2006. Formation of a functional thymus initiated by a postnatal epithelial progenitor cell. Nature 441(7096):992-6. [PubMed: 16791198]  [MGI Ref ID J:110046]

Boerboom D; Lafond JF; Zheng X; Lapointe E; Mittaz L; Boyer A; Pritchard MA; Demayo FJ; Mort JS; Drolet R; Richards JS. 2011. Partially redundant functions of Adamts1 and Adamts4 in the perinatal development of the renal medulla. Dev Dyn 240(7):1806-14. [PubMed: 21584905]  [MGI Ref ID J:172645]

Bond CT; Herson PS; Strassmaier T; Hammond R; Stackman R; Maylie J; Adelman JP. 2004. Small conductance Ca2+-activated K+ channel knock-out mice reveal the identity of calcium-dependent afterhyperpolarization currents. J Neurosci 24(23):5301-6. [PubMed: 15190101]  [MGI Ref ID J:94941]

Bouabe H; Liu Y; Moser M; Bosl MR; Heesemann J. 2011. Novel highly sensitive IL-10-beta-lactamase reporter mouse reveals cells of the innate immune system as a substantial source of IL-10 in vivo. J Immunol 187(6):3165-76. [PubMed: 21844394]  [MGI Ref ID J:179239]

Boulet AM; Capecchi MR. 2002. Duplication of the Hoxd11 gene causes alterations in the axial and appendicular skeleton of the mouse. Dev Biol 249(1):96-107. [PubMed: 12217321]  [MGI Ref ID J:78766]

Bowman-Colin C; Xia B; Bunting S; Klijn C; Drost R; Bouwman P; Fineman L; Chen X; Culhane AC; Cai H; Rodig SJ; Bronson RT; Jonkers J; Nussenzweig A; Kanellopoulou C; Livingston DM. 2013. Palb2 synergizes with Trp53 to suppress mammary tumor formation in a model of inherited breast cancer. Proc Natl Acad Sci U S A 110(21):8632-7. [PubMed: 23657012]  [MGI Ref ID J:197442]

Boyer A; Lapointe E; Zheng X; Cowan RG; Li H; Quirk SM; Demayo FJ; Richards JS; Boerboom D. 2010. WNT4 is required for normal ovarian follicle development and female fertility. FASEB J 24(8):3010-25. [PubMed: 20371632]  [MGI Ref ID J:162337]

Boyle K; Egan P; Rakar S; Willson TA; Wicks IP; Metcalf D; Hilton DJ; Nicola NA; Alexander WS; Roberts AW; Robb L. 2007. The SOCS box of suppressor of cytokine signaling-3 contributes to the control of G-CSF responsiveness in vivo. Blood 110(5):1466-74. [PubMed: 17510322]  [MGI Ref ID J:145513]

Bradley CK; Takano EA; Gothert JR; Gottgens B; Green AR; Begley CG; van Eekelen JA. 2007. Temporal regulation of Cre-recombinase activity in Scl-positive neurons of the central nervous system. Genesis 45(3):145-51. [PubMed: 17330263]  [MGI Ref ID J:121708]

Breiderhoff T; Christiansen GB; Pallesen LT; Vaegter C; Nykjaer A; Holm MM; Glerup S; Willnow TE. 2013. Sortilin-related receptor SORCS3 is a postsynaptic modulator of synaptic depression and fear extinction. PLoS One 8(9):e75006. [PubMed: 24069373]  [MGI Ref ID J:207532]

Buchert M; Athineos D; Abud HE; Burke ZD; Faux MC; Samuel MS; Jarnicki AG; Winbanks CE; Newton IP; Meniel VS; Suzuki H; Stacker SA; Nathke IS; Tosh D; Huelsken J; Clarke AR; Heath JK; Sansom OJ; Ernst M. 2010. Genetic dissection of differential signaling threshold requirements for the Wnt/beta-catenin pathway in vivo. PLoS Genet 6(1):e1000816. [PubMed: 20084116]  [MGI Ref ID J:156864]

Bujakowska K; Maubaret C; Chakarova CF; Tanimoto N; Beck SC; Fahl E; Humphries MM; Kenna PF; Makarov E; Makarova O; Paquet-Durand F; Ekstrom PA; van Veen T; Leveillard T; Humphries P; Seeliger MW; Bhattacharya SS. 2009. Study of gene-targeted mouse models of splicing factor gene Prpf31 implicated in human autosomal dominant retinitis pigmentosa (RP). Invest Ophthalmol Vis Sci 50(12):5927-33. [PubMed: 19578015]  [MGI Ref ID J:158261]

Busch K; Klapproth K; Barile M; Flossdorf M; Holland-Letz T; Schlenner SM; Reth M; Hofer T; Rodewald HR. 2015. Fundamental properties of unperturbed haematopoiesis from stem cells in vivo. Nature 518(7540):542-6. [PubMed: 25686605]  [MGI Ref ID J:219867]

Caldwell AS; Middleton LJ; Jimenez M; Desai R; McMahon AC; Allan CM; Handelsman DJ; Walters KA. 2014. Characterization of reproductive, metabolic, and endocrine features of polycystic ovary syndrome in female hyperandrogenic mouse models. Endocrinology 155(8):3146-59. [PubMed: 24877633]  [MGI Ref ID J:214371]

Caparros-Martin JA; Valencia M; Reytor E; Pacheco M; Fernandez M; Perez-Aytes A; Gean E; Lapunzina P; Peters H; Goodship JA; Ruiz-Perez VL. 2012. The ciliary Evc/Evc2 complex interacts with Smo and controls Hedgehog pathway activity in chondrocytes by regulating Sufu/Gli3 dissociation and Gli3 trafficking in primary cilia. Hum Mol Genet :. [PubMed: 23026747]  [MGI Ref ID J:188176]

Caruso N; Herberth B; Bartoli M; Puppo F; Dumonceaux J; Zimmermann A; Denadai S; Lebosse M; Roche S; Geng L; Magdinier F; Attarian S; Bernard R; Maina F; Levy N; Helmbacher F. 2013. Deregulation of the Protocadherin Gene FAT1 Alters Muscle Shapes: Implications for the Pathogenesis of Facioscapulohumeral Dystrophy. PLoS Genet 9(6):e1003550. [PubMed: 23785297]  [MGI Ref ID J:199157]

Catela C; Bilbao-Cortes D; Slonimsky E; Kratsios P; Rosenthal N; Te Welscher P. 2009. Multiple congenital malformations of Wolf-Hirschhorn syndrome are recapitulated in Fgfrl1 null mice. Dis Model Mech 2(5-6):283-94. [PubMed: 19383940]  [MGI Ref ID J:149673]

Chakraborty P; William Buaas F; Sharma M; Smith BE; Greenlee AR; Eacker SM; Braun RE. 2014. Androgen-dependent sertoli cell tight junction remodeling is mediated by multiple tight junction components. Mol Endocrinol 28(7):1055-72. [PubMed: 24825397]  [MGI Ref ID J:210656]

Charizanis K; Lee KY; Batra R; Goodwin M; Zhang C; Yuan Y; Shiue L; Cline M; Scotti MM; Xia G; Kumar A; Ashizawa T; Clark HB; Kimura T; Takahashi MP; Fujimura H; Jinnai K; Yoshikawa H; Gomes-Pereira M; Gourdon G; Sakai N; Nishino S; Foster TC; Ares M Jr;Darnell RB; Swanson MS. 2012. Muscleblind-like 2-mediated alternative splicing in the developing brain and dysregulation in myotonic dystrophy. Neuron 75(3):437-50. [PubMed: 22884328]  [MGI Ref ID J:218010]

Chen H; Zou Z; Sarratt KL; Zhou D; Zhang M; Sebzda E; Hammer DA; Kahn ML. 2006. In vivo beta1 integrin function requires phosphorylation-independent regulation by cytoplasmic tyrosines. Genes Dev 20(8):927-32. [PubMed: 16618804]  [MGI Ref ID J:108331]

Chen J; Bush JO; Ovitt CE; Lan Y; Jiang R. 2007. The TGF-beta pseudoreceptor gene Bambi is dispensable for mouse embryonic development and postnatal survival. Genesis 45(8):482-6. [PubMed: 17661381]  [MGI Ref ID J:125093]

Cheng XB; Jimenez M; Desai R; Middleton LJ; Joseph SR; Ning G; Allan CM; Smith JT; Handelsman DJ; Walters KA. 2013. Characterizing the neuroendocrine and ovarian defects of androgen receptor-knockout female mice. Am J Physiol Endocrinol Metab 305(6):E717-26. [PubMed: 23880317]  [MGI Ref ID J:202703]

Cheret C; Willem M; Fricker FR; Wende H; Wulf-Goldenberg A; Tahirovic S; Nave KA; Saftig P; Haass C; Garratt AN; Bennett DL; Birchmeier C. 2013. Bace1 and Neuregulin-1 cooperate to control formation and maintenance of muscle spindles. EMBO J 32(14):2015-28. [PubMed: 23792428]  [MGI Ref ID J:199150]

Cheung EC; Athineos D; Lee P; Ridgway RA; Lambie W; Nixon C; Strathdee D; Blyth K; Sansom OJ; Vousden KH. 2013. TIGAR Is Required for Efficient Intestinal Regeneration and Tumorigenesis. Dev Cell 25(5):463-77. [PubMed: 23726973]  [MGI Ref ID J:198650]

Ching S; Vilain E. 2009. Targeted disruption of Sonic Hedgehog in the mouse adrenal leads to adrenocortical hypoplasia. Genesis 47(9):628-37. [PubMed: 19536807]  [MGI Ref ID J:155992]

Chiou SH; Winters IP; Wang J; Naranjo S; Dudgeon C; Tamburini FB; Brady JJ; Yang D; Gruner BM; Chuang CH; Caswell DR; Zeng H; Chu P; Kim GE; Carpizo DR; Kim SK; Winslow MM. 2015. Pancreatic cancer modeling using retrograde viral vector delivery and in vivo CRISPR/Cas9-mediated somatic genome editing. Genes Dev :. [PubMed: 26178787]  [MGI Ref ID J:222466]

Cho H; Zhao X; Hatori M; Yu RT; Barish GD; Lam MT; Chong LW; DiTacchio L; Atkins AR; Glass CK; Liddle C; Auwerx J; Downes M; Panda S; Evans RM. 2012. Regulation of circadian behaviour and metabolism by REV-ERB-alpha and REV-ERB-beta. Nature 485(7396):123-7. [PubMed: 22460952]  [MGI Ref ID J:183855]

Christians JK; de Zwaan DR; Fung SH. 2013. Pregnancy associated plasma protein A2 (PAPP-A2) affects bone size and shape and contributes to natural variation in postnatal growth in mice. PLoS One 8(2):e56260. [PubMed: 23457539]  [MGI Ref ID J:199327]

Clausen BE; Waldburger JM; Schwenk F; Barras E; Mach B; Rajewsky K; Forster I; Reith W. 1998. Residual MHC class II expression on mature dendritic cells and activated B cells in RFX5-deficient mice. Immunity 8(2):143-55. [PubMed: 9491996]  [MGI Ref ID J:67941]

Colombo E; Tentorio P; Musio S; Rajewsky K; Pedotti R; Casola S; Farina C. 2014. Skewed B cell differentiation affects lymphoid organogenesis but not T cell-mediated autoimmunity. Clin Exp Immunol 176(1):58-65. [PubMed: 24325711]  [MGI Ref ID J:209296]

Constien R; Forde A; Liliensiek B; Grone HJ; Nawroth P; Hammerling G; Arnold B. 2001. Characterization of a novel EGFP reporter mouse to monitor Cre recombination as demonstrated by a Tie2 Cre mouse line. Genesis 30(1):36-44. [PubMed: 11353516]  [MGI Ref ID J:69949]

Conti FJ; Monkley SJ; Wood MR; Critchley DR; Muller U. 2009. Talin 1 and 2 are required for myoblast fusion, sarcomere assembly and the maintenance of myotendinous junctions. Development 136(21):3597-606. [PubMed: 19793892]  [MGI Ref ID J:153959]

Cook JR; Smaldone S; Cozzolino C; Del Solar M; Lee-Arteaga S; Nistala H; Ramirez F. 2012. Generation of Fbn1 conditional null mice implicates the extracellular microfibrils in osteoprogenitor recruitment. Genesis 50(8):635-41. [PubMed: 22374917]  [MGI Ref ID J:187484]

Cornish AL; Chong MM; Davey GM; Darwiche R; Nicola NA; Hilton DJ; Kay TW; Starr R; Alexander WS. 2003. Suppressor of cytokine signaling-1 regulates signaling in response to interleukin-2 and other gamma c-dependent cytokines in peripheral T cells. J Biol Chem 278(25):22755-61. [PubMed: 12665516]  [MGI Ref ID J:124411]

Coxam B; Sabine A; Bower NI; Smith KA; Pichol-Thievend C; Skoczylas R; Astin JW; Frampton E; Jaquet M; Crosier PS; Parton RG; Harvey NL; Petrova TV; Schulte-Merker S; Francois M; Hogan BM. 2014. Pkd1 regulates lymphatic vascular morphogenesis during development. Cell Rep 7(3):623-33. [PubMed: 24767999]  [MGI Ref ID J:211805]

Cronin T; Raffelsberger W; Lee-Rivera I; Jaillard C; Niepon ML; Kinzel B; Clerin E; Petrosian A; Picaud S; Poch O; Sahel JA; Leveillard T. 2010. The disruption of the rod-derived cone viability gene leads to photoreceptor dysfunction and susceptibility to oxidative stress. Cell Death Differ 17(7):1199-210. [PubMed: 20139892]  [MGI Ref ID J:186370]

Cushman LJ; Burrows HL; Seasholtz AF; Lewandoski M; Muzyczka N; Camper SA. 2000. Cre-mediated recombination in the pituitary gland Genesis 28(3-4):167-74. [PubMed: 11105060]  [MGI Ref ID J:66897]

Dakic A; Metcalf D; Di Rago L; Mifsud S; Wu L; Nutt SL. 2005. PU.1 regulates the commitment of adult hematopoietic progenitors and restricts granulopoiesis. J Exp Med 201(9):1487-502. [PubMed: 15867096]  [MGI Ref ID J:98188]

Dang MT; Yokoi F; McNaught KS; Jengelley TA; Jackson T; Li J; Li Y. 2005. Generation and characterization of Dyt1 DeltaGAG knock-in mouse as a model for early-onset dystonia. Exp Neurol 196(2):452-63. [PubMed: 16242683]  [MGI Ref ID J:104513]

Danilczyk U; Sarao R; Remy C; Benabbas C; Stange G; Richter A; Arya S; Pospisilik JA; Singer D; Camargo SM; Makrides V; Ramadan T; Verrey F; Wagner CA; Penninger JM. 2006. Essential role for collectrin in renal amino acid transport. Nature 444(7122):1088-91. [PubMed: 17167413]  [MGI Ref ID J:117490]

Dannappel M; Vlantis K; Kumari S; Polykratis A; Kim C; Wachsmuth L; Eftychi C; Lin J; Corona T; Hermance N; Zelic M; Kirsch P; Basic M; Bleich A; Kelliher M; Pasparakis M. 2014. RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis. Nature 513(7516):90-4. [PubMed: 25132550]  [MGI Ref ID J:217312]

Davey RA; Turner AG; McManus JF; Chiu WS; Tjahyono F; Moore AJ; Atkins GJ; Anderson PH; Ma C; Glatt V; MacLean HE; Vincent C; Bouxsein M; Morris HA; Findlay DM; Zajac JD. 2008. Calcitonin receptor plays a physiological role to protect against hypercalcemia in mice. J Bone Miner Res 23(8):1182-93. [PubMed: 18627265]  [MGI Ref ID J:150982]

De Fazio S; Bartonicek N; Di Giacomo M; Abreu-Goodger C; Sankar A; Funaya C; Antony C; Moreira PN; Enright AJ; O'Carroll D. 2011. The endonuclease activity of Mili fuels piRNA amplification that silences LINE1 elements. Nature 480(7376):259-63. [PubMed: 22020280]  [MGI Ref ID J:184034]

De Gasperi R; Rocher AB; Sosa MA; Wearne SL; Perez GM; Friedrich VL Jr; Hof PR; Elder GA. 2008. The IRG mouse: a two-color fluorescent reporter for assessing Cre-mediated recombination and imaging complex cellular relationships in situ. Genesis 46(6):308-17. [PubMed: 18543298]  [MGI Ref ID J:137251]

De Langhe SP; Carraro G; Tefft D; Li C; Xu X; Chai Y; Minoo P; Hajihosseini MK; Drouin J; Kaartinen V; Bellusci S. 2008. Formation and Differentiation of Multiple Mesenchymal Lineages during Lung Development Is Regulated by beta-catenin Signaling. PLoS ONE 3(1):e1516. [PubMed: 18231602]  [MGI Ref ID J:131535]

De Langhe SP; Carraro G; Warburton D; Hajihosseini MK; Bellusci S. 2006. Levels of mesenchymal FGFR2 signaling modulate smooth muscle progenitor cell commitment in the lung. Dev Biol 299(1):52-62. [PubMed: 16989802]  [MGI Ref ID J:114396]

Degenhardt KR; Milewski RC; Padmanabhan A; Miller M; Singh MK; Lang D; Engleka KA; Wu M; Li J; Zhou D; Antonucci N; Li L; Epstein JA. 2010. Distinct enhancers at the Pax3 locus can function redundantly to regulate neural tube and neural crest expressions. Dev Biol 339(2):519-27. [PubMed: 20045680]  [MGI Ref ID J:159124]

Deignan J; Lujan R; Bond C; Riegel A; Watanabe M; Williams JT; Maylie J; Adelman JP. 2012. SK2 and SK3 expression differentially affect firing frequency and precision in dopamine neurons. Neuroscience 217:67-76. [PubMed: 22554781]  [MGI Ref ID J:187145]

Di Giacomo M; Comazzetto S; Saini H; De Fazio S; Carrieri C; Morgan M; Vasiliauskaite L; Benes V; Enright AJ; O'Carroll D. 2013. Multiple epigenetic mechanisms and the piRNA pathway enforce LINE1 silencing during adult spermatogenesis. Mol Cell 50(4):601-8. [PubMed: 23706823]  [MGI Ref ID J:199259]

Ding L; Morrison SJ. 2013. Haematopoietic stem cells and early lymphoid progenitors occupy distinct bone marrow niches. Nature 495(7440):231-5. [PubMed: 23434755]  [MGI Ref ID J:194748]

Ding L; Saunders TL; Enikolopov G; Morrison SJ. 2012. Endothelial and perivascular cells maintain haematopoietic stem cells. Nature 481(7382):457-62. [PubMed: 22281595]  [MGI Ref ID J:180431]

Dixon CI; Rosahl TW; Stephens DN. 2008. Targeted deletion of the GABRA2 gene encoding alpha2-subunits of GABA(A) receptors facilitates performance of a conditioned emotional response, and abolishes anxiolytic effects of benzodiazepines and barbiturates. Pharmacol Biochem Behav 90(1):1-8. [PubMed: 18313124]  [MGI Ref ID J:140077]

Dougan SK; Hu CC; Paquet ME; Greenblatt MB; Kim J; Lilley BN; Watson N; Ploegh HL. 2011. Derlin-2-deficient mice reveal an essential role for protein dislocation in chondrocytes. Mol Cell Biol 31(6):1145-59. [PubMed: 21220515]  [MGI Ref ID J:170650]

Dours-Zimmermann MT; Maurer K; Rauch U; Stoffel W; Fassler R; Zimmermann DR. 2009. Versican V2 assembles the extracellular matrix surrounding the nodes of ranvier in the CNS. J Neurosci 29(24):7731-42. [PubMed: 19535585]  [MGI Ref ID J:150124]

Doyonnas R; LaBarge MA; Sacco A; Charlton C; Blau HM. 2004. Hematopoietic contribution to skeletal muscle regeneration by myelomonocytic precursors. Proc Natl Acad Sci U S A 101(37):13507-12. [PubMed: 15353585]  [MGI Ref ID J:92609]

DuBose AJ; Smith EY; Johnstone KA; Resnick JL. 2012. Temporal and developmental requirements for the Prader-Willi imprinting center. Proc Natl Acad Sci U S A 109(9):3446-50. [PubMed: 22331910]  [MGI Ref ID J:182162]

Dufner A; Duncan GS; Wakeham A; Elford AR; Hall HT; Ohashi PS; Mak TW. 2008. CARD6 is interferon inducible but not involved in nucleotide-binding oligomerization domain protein signaling leading to NF-kappaB activation. Mol Cell Biol 28(5):1541-52. [PubMed: 18160713]  [MGI Ref ID J:132634]

Dvoriantchikova G; Ivanov D; Barakat D; Grinberg A; Wen R; Slepak VZ; Shestopalov VI. 2012. Genetic ablation of Pannexin1 protects retinal neurons from ischemic injury. PLoS One 7(2):e31991. [PubMed: 22384122]  [MGI Ref ID J:196355]

Eckardt D; Theis M; Doring B; Speidel D; Willecke K; Ott T. 2004. Spontaneous ectopic recombination in cell-type-specific Cre mice removes loxP-flanked marker cassettes in vivo. Genesis 38(4):159-65. [PubMed: 15083516]  [MGI Ref ID J:90577]

Eckle T; Hughes K; Ehrentraut H; Brodsky KS; Rosenberger P; Choi DS; Ravid K; Weng T; Xia Y; Blackburn MR; Eltzschig HK. 2013. Crosstalk between the equilibrative nucleoside transporter ENT2 and alveolar Adora2b adenosine receptors dampens acute lung injury. FASEB J 27(8):3078-89. [PubMed: 23603835]  [MGI Ref ID J:203572]

El Malki K; Karbach SH; Huppert J; Zayoud M; Reissig S; Schuler R; Nikolaev A; Karram K; Munzel T; Kuhlmann CR; Luhmann HJ; von Stebut E; Wortge S; Kurschus FC; Waisman A. 2013. An alternative pathway of imiquimod-induced psoriasis-like skin inflammation in the absence of interleukin-17 receptor a signaling. J Invest Dermatol 133(2):441-51. [PubMed: 22951726]  [MGI Ref ID J:196483]

Emery EC; Young GT; Berrocoso EM; Chen L; McNaughton PA. 2011. HCN2 ion channels play a central role in inflammatory and neuropathic pain. Science 333(6048):1462-6. [PubMed: 21903816]  [MGI Ref ID J:176663]

Engelhard C; Sarsfield S; Merte J; Wang Q; Li P; Beppu H; Kolodkin AL; Sucov HM; Ginty DD. 2013. MEGF8 is a modifier of BMP signaling in trigeminal sensory neurons. Elife 2:e01160. [PubMed: 24052814]  [MGI Ref ID J:206541]

Epp N; Furstenberger G; Muller K; de Juanes S; Leitges M; Hausser I; Thieme F; Liebisch G; Schmitz G; Krieg P. 2007. 12R-lipoxygenase deficiency disrupts epidermal barrier function. J Cell Biol 177(1):173-82. [PubMed: 17403930]  [MGI Ref ID J:134709]

Ermolaeva MA; Michallet MC; Papadopoulou N; Utermohlen O; Kranidioti K; Kollias G; Tschopp J; Pasparakis M. 2008. Function of TRADD in tumor necrosis factor receptor 1 signaling and in TRIF-dependent inflammatory responses. Nat Immunol 9(9):1037-46. [PubMed: 18641654]  [MGI Ref ID J:139030]

Eroglu B; Moskophidis D; Mivechi NF. 2010. Loss of Hsp110 leads to age-dependent tau hyperphosphorylation and early accumulation of insoluble amyloid beta. Mol Cell Biol 30(19):4626-43. [PubMed: 20679486]  [MGI Ref ID J:164904]

Esposito G; Vitale AM; Leijten FP; Strik AM; Koonen-Reemst AM; Yurttas P; Robben TJ; Coonrod S; Gossen JA. 2007. Peptidylarginine deiminase (PAD) 6 is essential for oocyte cytoskeletal sheet formation and female fertility. Mol Cell Endocrinol 273(1-2):25-31. [PubMed: 17587491]  [MGI Ref ID J:138684]

Fairbridge NA; Dawe CE; Niri FH; Kooistra MK; King-Jones K; McDermid HE. 2010. Cecr2 mutations causing exencephaly trigger misregulation of mesenchymal/ectodermal transcription factors. Birth Defects Res A Clin Mol Teratol 88(8):619-25. [PubMed: 20589882]  [MGI Ref ID J:163648]

Fath T; Agnes Chan YK; Vrhovski B; Clarke H; Curthoys N; Hook J; Lemckert F; Schevzov G; Tam P; Watson CM; Khoo PL; Gunning P. 2010. New aspects of tropomyosin-regulated neuritogenesis revealed by the deletion of Tm5NM1 and 2. Eur J Cell Biol 89(7):489-98. [PubMed: 20223554]  [MGI Ref ID J:200894]

Faust N; Varas F; Kelly LM; Heck S; Graf T. 2000. Insertion of enhanced green fluorescent protein into the lysozyme gene creates mice with green fluorescent granulocytes and macrophages. Blood 96(2):719-26. [PubMed: 10887140]  [MGI Ref ID J:63254]

Fejes-Toth G; Frindt G; Naray-Fejes-Toth A; Palmer LG. 2008. Epithelial Na+ channel activation and processing in mice lacking SGK1. Am J Physiol Renal Physiol 294(6):F1298-305. [PubMed: 18385268]  [MGI Ref ID J:148648]

Feng L; Xie ZH; Ding Q; Xie X; Libby RT; Gan L. 2010. MATH5 controls the acquisition of multiple retinal cell fates. Mol Brain 3:36. [PubMed: 21087508]  [MGI Ref ID J:168595]

Fernandez-Miranda G; Trakala M; Martin J; Escobar B; Gonzalez A; Ghyselinck NB; Ortega S; Canamero M; de Castro IP; Malumbres M. 2011. Genetic disruption of aurora B uncovers an essential role for aurora C during early mammalian development. Development 138(13):2661-72. [PubMed: 21613325]  [MGI Ref ID J:173575]

Ferri AL; Cavallaro M; Braida D; Di Cristofano A; Canta A; Vezzani A; Ottolenghi S; Pandolfi PP; Sala M; DeBiasi S; Nicolis SK. 2004. Sox2 deficiency causes neurodegeneration and impaired neurogenesis in the adult mouse brain. Development 131(15):3805-19. [PubMed: 15240551]  [MGI Ref ID J:92063]

Finch AJ; Hilcenko C; Basse N; Drynan LF; Goyenechea B; Menne TF; Gonzalez Fernandez A; Simpson P; D'Santos CS; Arends MJ; Donadieu J; Bellanne-Chantelot C; Costanzo M; Boone C; McKenzie AN; Freund SM; Warren AJ. 2011. Uncoupling of GTP hydrolysis from eIF6 release on the ribosome causes Shwachman-Diamond syndrome. Genes Dev 25(9):917-29. [PubMed: 21536732]  [MGI Ref ID J:171416]

Foley SB; Hildenbrand ZL; Soyombo AA; Magee JA; Wu Y; Oravecz-Wilson KI; Ross TS. 2013. Expression of BCR/ABL p210 from a knockin allele enhances bone marrow engraftment without inducing neoplasia. Cell Rep 5(1):51-60. [PubMed: 24095735]  [MGI Ref ID J:203111]

Fotopoulou S; Oikonomou N; Grigorieva E; Nikitopoulou I; Paparountas T; Thanassopoulou A; Zhao Z; Xu Y; Kontoyiannis DL; Remboutsika E; Aidinis V. 2010. ATX expression and LPA signalling are vital for the development of the nervous system. Dev Biol 339(2):451-64. [PubMed: 20079728]  [MGI Ref ID J:159118]

Foukas LC; Claret M; Pearce W; Okkenhaug K; Meek S; Peskett E; Sancho S; Smith AJ; Withers DJ; Vanhaesebroeck B. 2006. Critical role for the p110alpha phosphoinositide-3-OH kinase in growth and metabolic regulation. Nature 441(7091):366-70. [PubMed: 16625210]  [MGI Ref ID J:109024]

Frank DU; Carter KL; Thomas KR; Burr RM; Bakker ML; Coetzee WA; Tristani-Firouzi M; Bamshad MJ; Christoffels VM; Moon AM. 2011. Lethal arrhythmias in Tbx3-deficient mice reveal extreme dosage sensitivity of cardiac conduction system function and homeostasis. Proc Natl Acad Sci U S A :. [PubMed: 22203979]  [MGI Ref ID J:179977]

Fromm G; Cadiz-Rivera B; de Vries C; Getman M; McGrath KE; Kingsley PD; Fields J; Fiering S; Bulger M. 2011. An embryonic stage-specific enhancer within the murine beta-globin locus mediates domain-wide histone hyperacetylation. Blood 117(19):5207-14. [PubMed: 21321362]  [MGI Ref ID J:173283]

Frommer F; Heinen TJ; Wunderlich FT; Yogev N; Buch T; Roers A; Bettelli E; Muller W; Anderton SM; Waisman A. 2008. Tolerance without clonal expansion: self-antigen-expressing B cells program self-reactive T cells for future deletion. J Immunol 181(8):5748-59. [PubMed: 18832734]  [MGI Ref ID J:140751]

Fu X; Kiyama T; Li R; Russell M; Klein WH; Mu X. 2009. Epitope-tagging Math5 and Pou4f2: New tools to study retinal ganglion cell development in the mouse. Dev Dyn 238(9):2309-2317. [PubMed: 19459208]  [MGI Ref ID J:151244]

Fuchs P; Zorer M; Reipert S; Rezniczek GA; Propst F; Walko G; Fischer I; Bauer J; Leschnik MW; Luscher B; Thalhammer JG; Lassmann H; Wiche G. 2009. Targeted inactivation of a developmentally regulated neural plectin isoform (plectin 1c) in mice leads to reduced motor nerve conduction velocity. J Biol Chem 284(39):26502-9. [PubMed: 19625254]  [MGI Ref ID J:155511]

Fuentes F; Zimmer D; Atienza M; Schottenfeld J; Penkala I; Bale T; Bence KK; Arregui CO. 2012. Protein tyrosine phosphatase PTP1B is involved in hippocampal synapse formation and learning. PLoS One 7(7):e41536. [PubMed: 22844492]  [MGI Ref ID J:189720]

Galli A; Robay D; Osterwalder M; Bao X; Benazet JD; Tariq M; Paro R; Mackem S; Zeller R. 2010. Distinct roles of Hand2 in initiating polarity and posterior Shh expression during the onset of mouse limb bud development. PLoS Genet 6(4):e1000901. [PubMed: 20386744]  [MGI Ref ID J:159210]

Gambardella L; Hemberger M; Hughes B; Zudaire E; Andrews S; Vermeren S. 2010. PI3K signaling through the dual GTPase-activating protein ARAP3 is essential for developmental angiogenesis. Sci Signal 3(145):ra76. [PubMed: 20978237]  [MGI Ref ID J:185401]

Gangloff YG; Mueller M; Dann SG; Svoboda P; Sticker M; Spetz JF; Um SH; Brown EJ; Cereghini S; Thomas G; Kozma SC. 2004. Disruption of the mouse mTOR gene leads to early postimplantation lethality and prohibits embryonic stem cell development. Mol Cell Biol 24(21):9508-16. [PubMed: 15485918]  [MGI Ref ID J:94133]

Garbi N; Tanaka S; Momburg F; Hammerling GJ. 2006. Impaired assembly of the major histocompatibility complex class I peptide-loading complex in mice deficient in the oxidoreductase ERp57. Nat Immunol 7(1):93-102. [PubMed: 16311600]  [MGI Ref ID J:112606]

Garcia-Higuera I; Manchado E; Dubus P; Canamero M; Mendez J; Moreno S; Malumbres M. 2008. Genomic stability and tumour suppression by the APC/C cofactor Cdh1. Nat Cell Biol 10(7):802-11. [PubMed: 18552834]  [MGI Ref ID J:137456]

Garcia-Lavandeira M; Quereda V; Flores I; Saez C; Diaz-Rodriguez E; Japon MA; Ryan AK; Blasco MA; Dieguez C; Malumbres M; Alvarez CV. 2009. A GRFa2/Prop1/stem (GPS) cell niche in the pituitary. PLoS ONE 4(3):e4815. [PubMed: 19283075]  [MGI Ref ID J:147363]

Genetic Resource Science at The Jackson Laboratory. 2008. Expression/Specificity Patterns of Cre Alleles Direct Data Submission from Genetic Resource Science :.  [MGI Ref ID J:137887]

Geng R; Melki S; Chen DH; Tian G; Furness DN; Oshima-Takago T; Neef J; Moser T; Askew C; Horwitz G; Holt JR; Imanishi Y; Alagramam KN. 2012. The Mechanosensory Structure of the Hair Cell Requires Clarin-1, a Protein Encoded by Usher Syndrome III Causative Gene. J Neurosci 32(28):9485-9498. [PubMed: 22787034]  [MGI Ref ID J:186316]

Gerbaulet A; Wickenhauser C; Scholten J; Peschke K; Drube S; Horny HP; Kamradt T; Naumann R; Muller W; Krieg T; Waskow C; Hartmann K; Roers A. 2011. Mast cell hyperplasia, B-cell malignancy, and intestinal inflammation in mice with conditional expression of a constitutively active kit. Blood 117(6):2012-21. [PubMed: 21148330]  [MGI Ref ID J:169611]

Gewies A; Castineiras-Vilarino M; Ferch U; Jahrling N; Heinrich K; Hoeckendorf U; Przemeck GK; Munding M; Gross O; Schroeder T; Horsch M; Karran EL; Majid A; Antonowicz S; Beckers J; Hrabe de Angelis M; Dodt HU; Peschel C; Forster I; Dyer MJ; Ruland J. 2013. Prdm6 is essential for cardiovascular development in vivo. PLoS One 8(11):e81833. [PubMed: 24278461]  [MGI Ref ID J:209773]

Gigoux M; Shang J; Pak Y; Xu M; Choe J; Mak TW; Suh WK. 2009. Inducible costimulator promotes helper T-cell differentiation through phosphoinositide 3-kinase. Proc Natl Acad Sci U S A 106(48):20371-6. [PubMed: 19915142]  [MGI Ref ID J:155586]

Gilfillan S; Ho EL; Cella M; Yokoyama WM; Colonna M. 2002. NKG2D recruits two distinct adapters to trigger NK cell activation and costimulation. Nat Immunol 3(12):1150-5. [PubMed: 12426564]  [MGI Ref ID J:80426]

Glasl L; Kloos K; Giesert F; Roethig A; Di Benedetto B; Kuhn R; Zhang J; Hafen U; Zerle J; Hofmann A; Hrabe de Angelis M; Winklhofer KF; Holter SM; Vogt Weisenhorn DM; Wurst W. 2012. Pink1-deficiency in mice impairs gait, olfaction and serotonergic innervation of the olfactory bulb. Exp Neurol 235(1):214-27. [PubMed: 22265660]  [MGI Ref ID J:183290]

Goldman DC; Hackenmiller R; Nakayama T; Sopory S; Wong C; Kulessa H; Christian JL. 2006. Mutation of an upstream cleavage site in the BMP4 prodomain leads to tissue-specific loss of activity. Development 133(10):1933-42. [PubMed: 16624858]  [MGI Ref ID J:108516]

Goldmann T; Wieghofer P; Muller PF; Wolf Y; Varol D; Yona S; Brendecke SM; Kierdorf K; Staszewski O; Datta M; Luedde T; Heikenwalder M; Jung S; Prinz M. 2013. A new type of microglia gene targeting shows TAK1 to be pivotal in CNS autoimmune inflammation. Nat Neurosci 16(11):1618-26. [PubMed: 24077561]  [MGI Ref ID J:207425]

Gothert JR; Gustin SE; van Eekelen JA; Schmidt U; Hall MA; Jane SM; Green AR; Gottgens B; Izon DJ; Begley CG. 2004. Genetically tagging endothelial cells in vivo: bone marrow-derived cells do not contribute to tumor endothelium. Blood 104(6):1769-77. [PubMed: 15187022]  [MGI Ref ID J:92965]

Graf C; Niwa S; Muller M; Kinzel B; Bornancin F. 2008. Wild-type levels of ceramide and ceramide-1-phosphate in the retina of ceramide kinase-like-deficient mice. Biochem Biophys Res Commun 373(1):159-63. [PubMed: 18555012]  [MGI Ref ID J:137892]

Grange M; Buferne M; Verdeil G; Leserman L; Schmitt-Verhulst AM; Auphan-Anezin N. 2012. Activated STAT5 promotes long-lived cytotoxic CD8+ T cells that induce regression of autochthonous melanoma. Cancer Res 72(1):76-87. [PubMed: 22065720]  [MGI Ref ID J:181044]

Greenblatt S; Li L; Slape C; Nguyen B; Novak R; Duffield A; Huso D; Desiderio S; Borowitz MJ; Aplan P; Small D. 2012. Knock-in of a FLT3/ITD mutation cooperates with a NUP98-HOXD13 fusion to generate acute myeloid leukemia in a mouse model. Blood 119(12):2883-94. [PubMed: 22323452]  [MGI Ref ID J:182518]

Grier JD; Xiong S; Elizondo-Fraire AC; Parant JM; Lozano G. 2006. Tissue-Specific Differences of p53 Inhibition by Mdm2 and Mdm4. Mol Cell Biol 26(1):192-8. [PubMed: 16354690]  [MGI Ref ID J:104114]

Grossmann KS; Wende H; Paul FE; Cheret C; Garratt AN; Zurborg S; Feinberg K; Besser D; Schulz H; Peles E; Selbach M; Birchmeier W; Birchmeier C. 2009. The tyrosine phosphatase Shp2 (PTPN11) directs Neuregulin-1/ErbB signaling throughout Schwann cell development. Proc Natl Acad Sci U S A 106(39):16704-9. [PubMed: 19805360]  [MGI Ref ID J:153219]

Gu C; Rodriguez ER; Reimert DV; Shu T; Fritzsch B; Richards LJ; Kolodkin AL; Ginty DD. 2003. Neuropilin-1 conveys semaphorin and VEGF signaling during neural and cardiovascular development. Dev Cell 5(1):45-57. [PubMed: 12852851]  [MGI Ref ID J:93799]

Guerra C; Mijimolle N; Dhawahir A; Dubus P; Barradas M; Serrano M; Campuzano V; Barbacid M. 2003. Tumor induction by an endogenous K-ras oncogene is highly dependent on cellular context. Cancer Cell 4(2):111-20. [PubMed: 12957286]  [MGI Ref ID J:86101]

Guimera J; Weisenhorn DV; Wurst W. 2006. Megane/Heslike is required for normal GABAergic differentiation in the mouse superior colliculus. Development 133(19):3847-57. [PubMed: 16968817]  [MGI Ref ID J:119562]

Gunther S; Kim J; Kostin S; Lepper C; Fan CM; Braun T. 2013. Myf5-positive satellite cells contribute to pax7-dependent long-term maintenance of adult muscle stem cells. Cell Stem Cell 13(5):590-601. [PubMed: 23933088]  [MGI Ref ID J:202693]

Gunton JE; Sisavanh M; Stokes RA; Satin J; Satin LS; Zhang M; Liu SM; Cai W; Cheng K; Cooney GJ; Laybutt DR; So T; Molero JC; Grey ST; Andres DA; Rolph MS; Mackay CR. 2012. Mice deficient in GEM GTPase show abnormal glucose homeostasis due to defects in beta-cell calcium handling. PLoS One 7(6):e39462. [PubMed: 22761801]  [MGI Ref ID J:187922]

Guo N; Hawkins C; Nathans J. 2004. Frizzled6 controls hair patterning in mice. Proc Natl Acad Sci U S A 101(25):9277-81. [PubMed: 15169958]  [MGI Ref ID J:91412]

Gupta A; Wodziak D; Tun M; Bouley DM; Lowe AW. 2013. Loss of anterior gradient 2 (Agr2) expression results in hyperplasia and defective lineage maturation in the murine stomach. J Biol Chem 288(6):4321-33. [PubMed: 23209296]  [MGI Ref ID J:195573]

Gurniak CB; Perlas E; Witke W. 2005. The actin depolymerizing factor n-cofilin is essential for neural tube morphogenesis and neural crest cell migration. Dev Biol 278(1):231-41. [PubMed: 15649475]  [MGI Ref ID J:96452]

Hambsch B; Grinevich V; Seeburg PH; Schwarz MK. 2005. {gamma}-Protocadherins, presenilin-mediated release of C-terminal fragment promotes locus expression. J Biol Chem 280(16):15888-97. [PubMed: 15711011]  [MGI Ref ID J:98737]

Hammond RS; Bond CT; Strassmaier T; Ngo-Anh TJ; Adelman JP; Maylie J; Stackman RW. 2006. Small-conductance Ca2+-activated K+ channel type 2 (SK2) modulates hippocampal learning, memory, and synaptic plasticity. J Neurosci 26(6):1844-53. [PubMed: 16467533]  [MGI Ref ID J:105645]

Hao Z; Duncan GS; Su YW; Li WY; Silvester J; Hong C; You H; Brenner D; Gorrini C; Haight J; Wakeham A; You-Ten A; McCracken S; Elia A; Li Q; Detmar J; Jurisicova A; Hobeika E; Reth M; Sheng Y; Lang PA; Ohashi PS; Zhong Q; Wang X; Mak TW. 2012. The E3 ubiquitin ligase Mule acts through the ATM-p53 axis to maintain B lymphocyte homeostasis. J Exp Med 209(1):173-86. [PubMed: 22213803]  [MGI Ref ID J:181705]

Hart AH; Hartley L; Sourris K; Stadler ES; Li R; Stanley EG; Tam PP; Elefanty AG; Robb L. 2002. Mixl1 is required for axial mesendoderm morphogenesis and patterning in the murine embryo. Development 129(15):3597-608. [PubMed: 12117810]  [MGI Ref ID J:77443]

Hartenstein B; Dittrich BT; Stickens D; Heyer B; Vu TH; Teurich S; Schorpp-Kistner M; Werb Z; Angel P. 2006. Epidermal development and wound healing in matrix metalloproteinase 13-deficient mice. J Invest Dermatol 126(2):486-96. [PubMed: 16374453]  [MGI Ref ID J:104953]

Hartleben B; Widmeier E; Wanner N; Schmidts M; Kim ST; Schneider L; Mayer B; Kerjaschki D; Miner JH; Walz G; Huber TB. 2012. Role of the polarity protein Scribble for podocyte differentiation and maintenance. PLoS One 7(5):e36705. [PubMed: 22586490]  [MGI Ref ID J:190169]

Harzheim D; Pfeiffer KH; Fabritz L; Kremmer E; Buch T; Waisman A; Kirchhof P; Kaupp UB; Seifert R. 2008. Cardiac pacemaker function of HCN4 channels in mice is confined to embryonic development and requires cyclic AMP. EMBO J 27(4):692-703. [PubMed: 18219271]  [MGI Ref ID J:131820]

He H; Mahnke AH; Doyle S; Fan N; Wang CC; Hall BJ; Tang YP; Inglis FM; Chen C; Erickson JD. 2012. Neurodevelopmental role for VGLUT2 in pyramidal neuron plasticity, dendritic refinement, and in spatial learning. J Neurosci 32(45):15886-901. [PubMed: 23136427]  [MGI Ref ID J:192240]

He M; Liu Y; Wang X; Zhang MQ; Hannon GJ; Huang ZJ. 2012. Cell-Type-Based Analysis of MicroRNA Profiles in the Mouse Brain. Neuron 73(1):35-48. [PubMed: 22243745]  [MGI Ref ID J:179351]

He N; Xiao Z; Yin T; Stubbs J; Li L; Quarles LD. 2010. Inducible expression of Runx2 results in multiorgan abnormalities in mice. J Cell Biochem :. [PubMed: 21136430]  [MGI Ref ID J:171769]

He N; Xiao Z; Yin T; Stubbs J; Li L; Quarles LD. 2011. Inducible expression of Runx2 results in multiorgan abnormalities in mice. J Cell Biochem 112(2):653-65. [PubMed: 21268087]  [MGI Ref ID J:168061]

Heinen TJ; Staubach F; Haming D; Tautz D. 2009. Emergence of a new gene from an intergenic region. Curr Biol 19(18):1527-31. [PubMed: 19733073]  [MGI Ref ID J:154651]

Heinze C; Seniuk A; Sokolov MV; Huebner AK; Klementowicz AE; Szijarto IA; Schleifenbaum J; Vitzthum H; Gollasch M; Ehmke H; Schroeder BC; Hubner CA. 2014. Disruption of vascular Ca2+-activated chloride currents lowers blood pressure. J Clin Invest 124(2):675-86. [PubMed: 24401273]  [MGI Ref ID J:207993]

Hemmers S; Teijaro JR; Arandjelovic S; Mowen KA. 2011. PAD4-Mediated Neutrophil Extracellular Trap Formation Is Not Required for Immunity against Influenza Infection. PLoS One 6(7):e22043. [PubMed: 21779371]  [MGI Ref ID J:174934]

Herrmann T; Muckenthaler M; van der Hoeven F; Brennan K; Gehrke SG; Hubert N; Sergi C; Grone HJ; Kaiser I; Gosch I; Volkmann M; Riedel HD; Hentze MW; Stewart AF; Stremmel W. 2004. Iron overload in adult Hfe-deficient mice independent of changes in the steady-state expression of the duodenal iron transporters DMT1 and Ireg1/ferroportin. J Mol Med 82(1):39-48. [PubMed: 14618243]  [MGI Ref ID J:132141]

Herrmann T; van der Hoeven F; Grone HJ; Stewart AF; Langbein L; Kaiser I; Liebisch G; Gosch I; Buchkremer F; Drobnik W; Schmitz G; Stremmel W. 2003. Mice with targeted disruption of the fatty acid transport protein 4 (Fatp 4, Slc27a4) gene show features of lethal restrictive dermopathy. J Cell Biol 161(6):1105-15. [PubMed: 12821645]  [MGI Ref ID J:84096]

Herzig MC; Kolly C; Persohn E; Theil D; Schweizer T; Hafner T; Stemmelen C; Troxler TJ; Schmid P; Danner S; Schnell CR; Mueller M; Kinzel B; Grevot A; Bolognani F; Stirn M; Kuhn RR; Kaupmann K; van der Putten PH; Rovelli G; Shimshek DR. 2011. LRRK2 protein levels are determined by kinase function and are crucial for kidney and lung homeostasis in mice. Hum Mol Genet 20(21):4209-23. [PubMed: 21828077]  [MGI Ref ID J:176679]

High FA; Lu MM; Pear WS; Loomes KM; Kaestner KH; Epstein JA. 2008. Endothelial expression of the Notch ligand Jagged1 is required for vascular smooth muscle development. Proc Natl Acad Sci U S A 105(6):1955-9. [PubMed: 18245384]  [MGI Ref ID J:143962]

Hildner K; Edelson BT; Purtha WE; Diamond M; Matsushita H; Kohyama M; Calderon B; Schraml BU; Unanue ER; Diamond MS; Schreiber RD; Murphy TL; Murphy KM. 2008. Batf3 deficiency reveals a critical role for CD8alpha+ dendritic cells in cytotoxic T cell immunity. Science 322(5904):1097-100. [PubMed: 19008445]  [MGI Ref ID J:141064]

Ho Y; Shewchuk BM; Liebhaber SA; Cooke NE. 2013. Distinct chromatin configurations regulate the initiation and the maintenance of hGH gene expression. Mol Cell Biol 33(9):1723-34. [PubMed: 23428872]  [MGI Ref ID J:203757]

Hoegg-Beiler MB; Sirisi S; Orozco IJ; Ferrer I; Hohensee S; Auberson M; Godde K; Vilches C; de Heredia ML; Nunes V; Estevez R; Jentsch TJ. 2014. Disrupting MLC1 and GlialCAM and ClC-2 interactions in leukodystrophy entails glial chloride channel dysfunction. Nat Commun 5:3475. [PubMed: 24647135]  [MGI Ref ID J:210308]

Hori K; Cholewa-Waclaw J; Nakada Y; Glasgow SM; Masui T; Henke RM; Wildner H; Martarelli B; Beres TM; Epstein JA; Magnuson MA; Macdonald RJ; Birchmeier C; Johnson JE. 2008. A nonclassical bHLH Rbpj transcription factor complex is required for specification of GABAergic neurons independent of Notch signaling. Genes Dev 22(2):166-78. [PubMed: 18198335]  [MGI Ref ID J:130251]

Howard PW; Howard TL; Maurer RA. 2010. Generation of mice with a conditional allele for Ift172. Transgenic Res 19(1):121-6. [PubMed: 19521792]  [MGI Ref ID J:156426]

Howell OW; Scharfman HE; Herzog H; Sundstrom LE; Beck-Sickinger A; Gray WP. 2003. Neuropeptide Y is neuroproliferative for post-natal hippocampal precursor cells. J Neurochem 86(3):646-59. [PubMed: 12859678]  [MGI Ref ID J:92582]

Hu X; Bulger M; Roach JN; Eszterhas SK; Olivier E; Bouhassira EE; Groudine MT; Fiering S. 2003. Promoters of the murine embryonic beta-like globin genes Ey and betah1 do not compete for interaction with the beta-globin locus control region. Proc Natl Acad Sci U S A 100(3):1111-5. [PubMed: 12525692]  [MGI Ref ID J:82296]

Huang J; Elicker J; Bowens N; Liu X; Cheng L; Cappola TP; Zhu X; Parmacek MS. 2012. Myocardin regulates BMP10 expression and is required for heart development. J Clin Invest 122(10):3678-91. [PubMed: 22996691]  [MGI Ref ID J:192465]

Huijbers IJ; Krimpenfort P; Chomez P; van der Valk MA; Song JY; Inderberg-Suso EM; Schmitt-Verhulst AM; Berns A; Van den Eynde BJ. 2006. An inducible mouse model of melanoma expressing a defined tumor antigen. Cancer Res 66(6):3278-86. [PubMed: 16540681]  [MGI Ref ID J:107175]

Huijbers IJ; Soudja SM; Uyttenhove C; Buferne M; Inderberg-Suso EM; Colau D; Pilotte L; Powis de Tenbossche CG; Chomez P; Brasseur F; Schmitt-Verhulst AM; Van den Eynde BJ. 2012. Minimal tolerance to a tumor antigen encoded by a cancer-germline gene. J Immunol 188(1):111-21. [PubMed: 22140254]  [MGI Ref ID J:180807]

Hundahl CA; Fahrenkrug J; Hay-Schmidt A; Georg B; Faltoft B; Hannibal J. 2012. Circadian behaviour in neuroglobin deficient mice. PLoS One 7(4):e34462. [PubMed: 22496809]  [MGI Ref ID J:187107]

Iijima T; Iijima Y; Witte H; Scheiffele P. 2014. Neuronal cell type-specific alternative splicing is regulated by the KH domain protein SLM1. J Cell Biol 204(3):331-42. [PubMed: 24469635]  [MGI Ref ID J:208331]

Illert AL; Kawaguchi H; Antinozzi C; Bassermann F; Quintanilla-Martinez L; von Klitzing C; Hiwatari M; Peschel C; de Rooij DG; Morris SW; Barchi M; Duyster J. 2012. Targeted inactivation of nuclear interaction partner of ALK disrupts meiotic prophase. Development 139(14):2523-34. [PubMed: 22696294]  [MGI Ref ID J:185584]

Ishikawa TO; Herschman HR. 2010. Conditional Bicistronic Cre Reporter Line Expressing Both Firefly Luciferase and beta-galactosidase. Mol Imaging Biol :. [PubMed: 20495880]  [MGI Ref ID J:165837]

Iwanaga Y; Chi YH; Miyazato A; Sheleg S; Haller K; Peloponese JM Jr; Li Y; Ward JM; Benezra R; Jeang KT. 2007. Heterozygous deletion of mitotic arrest-deficient protein 1 (MAD1) increases the incidence of tumors in mice. Cancer Res 67(1):160-6. [PubMed: 17210695]  [MGI Ref ID J:117337]

Jagle U; Gasser JA; Muller M; Kinzel B. 2007. Conditional transgene expression mediated by the mouse beta-actin locus. Genesis 45(11):659-66. [PubMed: 17987666]  [MGI Ref ID J:129105]

Jaillard C; Mouret A; Niepon ML; Clerin E; Yang Y; Lee-Rivera I; Ait-Ali N; Millet-Puel G; Cronin T; Sedmak T; Raffelsberger W; Kinzel B; Trembleau A; Poch O; Bennett J; Wolfrum U; Lledo PM; Sahel JA; Leveillard T. 2012. Nxnl2 splicing results in dual functions in neuronal cell survival and maintenance of cell integrity. Hum Mol Genet 21(10):2298-311. [PubMed: 22343139]  [MGI Ref ID J:183790]

Jeannet R; Mastio J; Macias-Garcia A; Oravecz A; Ashworth T; Geimer Le Lay AS; Jost B; Le Gras S; Ghysdael J; Gridley T; Honjo T; Radtke F; Aster JC; Chan S; Kastner P. 2010. Oncogenic activation of the Notch1 gene by deletion of its promoter in Ikaros-deficient T-ALL. Blood 116(25):5443-54. [PubMed: 20829372]  [MGI Ref ID J:167410]

Jennemann R; Sandhoff R; Wang S; Kiss E; Gretz N; Zuliani C; Martin-Villalba A; Jager R; Schorle H; Kenzelmann M; Bonrouhi M; Wiegandt H; Grone HJ. 2005. Cell-specific deletion of glucosylceramide synthase in brain leads to severe neural defects after birth. Proc Natl Acad Sci U S A 102(35):12459-64. [PubMed: 16109770]  [MGI Ref ID J:101155]

John A; Brylka H; Wiegreffe C; Simon R; Liu P; Juttner R; Crenshaw EB 3rd; Luyten FP; Jenkins NA; Copeland NG; Birchmeier C; Britsch S. 2012. Bcl11a is required for neuronal morphogenesis and sensory circuit formation in dorsal spinal cord development. Development 139(10):1831-41. [PubMed: 22491945]  [MGI Ref ID J:184011]

Johnson TM; Meade K; Pathak N; Marques MR; Attardi LD. 2008. Knockin mice expressing a chimeric p53 protein reveal mechanistic differences in how p53 triggers apoptosis and senescence. Proc Natl Acad Sci U S A 105(4):1215-20. [PubMed: 18216268]  [MGI Ref ID J:131856]

Johnstone SR; Kroncke BM; Straub AC; Best AK; Dunn CA; Mitchell LA; Peskova Y; Nakamoto RK; Koval M; Lo CW; Lampe PD; Columbus L; Isakson BE. 2012. MAPK phosphorylation of connexin 43 promotes binding of cyclin E and smooth muscle cell proliferation. Circ Res 111(2):201-11. [PubMed: 22652908]  [MGI Ref ID J:212895]

Jonkers J; Meuwissen R; van Der Gulden H; Peterse H; van Der Valk M; Berns A. 2001. Synergistic tumor suppressor activity of BRCA2 and p53 in a conditional mouse model for breast cancer. Nat Genet 29(4):418-25. [PubMed: 11694875]  [MGI Ref ID J:73028]

Joshi PS; Molyneaux BJ; Feng L; Xie X; Macklis JD; Gan L. 2008. Bhlhb5 regulates the postmitotic acquisition of area identities in layers II-V of the developing neocortex. Neuron 60(2):258-72. [PubMed: 18957218]  [MGI Ref ID J:144066]

Jouffe C; Cretenet G; Symul L; Martin E; Atger F; Naef F; Gachon F. 2013. The circadian clock coordinates ribosome biogenesis. PLoS Biol 11(1):e1001455. [PubMed: 23300384]  [MGI Ref ID J:194495]

Kalebic N; Sorrentino S; Perlas E; Bolasco G; Martinez C; Heppenstall PA. 2013. alphaTAT1 is the major alpha-tubulin acetyltransferase in mice. Nat Commun 4:1962. [PubMed: 23748901]  [MGI Ref ID J:205737]

Kamata T; Hussain J; Giblett S; Hayward R; Marais R; Pritchard C. 2010. BRAF inactivation drives aneuploidy by deregulating CRAF. Cancer Res 70(21):8475-86. [PubMed: 20978199]  [MGI Ref ID J:166215]

Kan NG; Stemmler MP; Junghans D; Kanzler B; de Vries WN; Dominis M; Kemler R. 2007. Gene replacement reveals a specific role for E-cadherin in the formation of a functional trophectoderm. Development 134(1):31-41. [PubMed: 17138661]  [MGI Ref ID J:117056]

Kask K; Zamanillo D; Rozov A; Burnashev N; Sprengel R; Seeburg PH. 1998. The AMPA receptor subunit GluR-B in its Q/R site-unedited form is not essential for brain development and function. Proc Natl Acad Sci U S A 95(23):13777-82. [PubMed: 9811877]  [MGI Ref ID J:50929]

Kaufmann T; Tai L; Ekert PG; Huang DC; Norris F; Lindemann RK; Johnstone RW; Dixit VM; Strasser A. 2007. The BH3-only protein bid is dispensable for DNA damage- and replicative stress-induced apoptosis or cell-cycle arrest. Cell 129(2):423-33. [PubMed: 17448999]  [MGI Ref ID J:158191]

Kautschitsch S; Andersen L; Hammerschmid S; Rulicke T. 2014. Rapid identification of targeted transgene integrations in ES cells by fluorescence detection. Transgenic Res 23(3):469-75. [PubMed: 24482264]  [MGI Ref ID J:213521]

Ke F; Voss A; Kerr JB; O'Reilly LA; Tai L; Echeverry N; Bouillet P; Strasser A; Kaufmann T. 2012. BCL-2 family member BOK is widely expressed but its loss has only minimal impact in mice. Cell Death Differ 19(6):915-25. [PubMed: 22281706]  [MGI Ref ID J:203179]

Kellendonk C; Tronche F; Casanova E; Anlag K; Opherk C; Schutz G. 1999. Inducible site-specific recombination in the brain. J Mol Biol 285(1):175-82. [PubMed: 9878397]  [MGI Ref ID J:69323]

Keller C; Hansen MS; Coffin CM; Capecchi MR. 2004. Pax3:Fkhr interferes with embryonic Pax3 and Pax7 function: implications for alveolar rhabdomyosarcoma cell of origin. Genes Dev 18(21):2608-13. [PubMed: 15520281]  [MGI Ref ID J:93443]

Kim Y; Zheng Y. 2013. Generation and characterization of a conditional deletion allele for Lmna in mice. Biochem Biophys Res Commun 440(1):8-13. [PubMed: 23998933]  [MGI Ref ID J:211369]

Kimmel RA; Turnbull DH; Blanquet V; Wurst W; Loomis CA; Joyner AL. 2000. Two lineage boundaries coordinate vertebrate apical ectodermal ridge formation. Genes Dev 14(11):1377-89. [PubMed: 10837030]  [MGI Ref ID J:62572]

Kirstetter P; Anderson K; Porse BT; Jacobsen SE; Nerlov C. 2006. Activation of the canonical Wnt pathway leads to loss of hematopoietic stem cell repopulation and multilineage differentiation block. Nat Immunol 7(10):1048-56. [PubMed: 16951689]  [MGI Ref ID J:112660]

Kirstetter P; Schuster MB; Bereshchenko O; Moore S; Dvinge H; Kurz E; Theilgaard-Monch K; Mansson R; Pedersen TA; Pabst T; Schrock E; Porse BT; Jacobsen SE; Bertone P; Tenen DG; Nerlov C. 2008. Modeling of C/EBPalpha mutant acute myeloid leukemia reveals a common expression signature of committed myeloid leukemia-initiating cells. Cancer Cell 13(4):299-310. [PubMed: 18394553]  [MGI Ref ID J:136134]

Kleiter I; Song J; Lukas D; Hasan M; Neumann B; Croxford AL; Pedre X; Hovelmeyer N; Yogev N; Mildner A; Prinz M; Wiese E; Reifenberg K; Bittner S; Wiendl H; Steinman L; Becker C; Bogdahn U; Neurath MF; Steinbrecher A; Waisman A. 2010. Smad7 in T cells drives T helper 1 responses in multiple sclerosis and experimental autoimmune encephalomyelitis. Brain 133(Pt 4):1067-81. [PubMed: 20354004]  [MGI Ref ID J:184670]

Klesney-Tait J; Keck K; Li X; Gilfillan S; Otero K; Baruah S; Meyerholz DK; Varga SM; Knudson CJ; Moninger TO; Moreland J; Zabner J; Colonna M. 2013. Transepithelial migration of neutrophils into the lung requires TREM-1. J Clin Invest 123(1):138-49. [PubMed: 23241959]  [MGI Ref ID J:194295]

Kopp J; Xu ZQ; Zhang X; Pedrazzini T; Herzog H; Kresse A; Wong H; Walsh JH; Hokfelt T. 2002. Expression of the neuropeptide Y Y1 receptor in the CNS of rat and of wild-type and Y1 receptor knock-out mice. Focus on immunohistochemical localization. Neuroscience 111(3):443-532. [PubMed: 12031341]  [MGI Ref ID J:167683]

Kordowich S; Serup P; Collombat P; Mansouri A. 2012. Generation of animals allowing the conditional inactivation of the Pax4 gene. Transgenic Res 21(6):1215-20. [PubMed: 22717987]  [MGI Ref ID J:192683]

Krautzberger AM; Kosiol B; Scholze M; Schrewe H. 2012. Expression of vasorin (Vasn) during embryonic development of the mouse. Gene Expr Patterns 12(5-6):167-71. [PubMed: 22426063]  [MGI Ref ID J:183876]

Krechowec SO; Burton KL; Newlaczyl AU; Nunn N; Vlatkovic N; Plagge A. 2012. Postnatal changes in the expression pattern of the imprinted signalling protein XLalphas underlie the changing phenotype of deficient mice. PLoS One 7(1):e29753. [PubMed: 22253771]  [MGI Ref ID J:184320]

Kritzer MD; Li J; Passariello CL; Gayanilo M; Thakur H; Dayan J; Dodge-Kafka K; Kapiloff MS. 2014. The scaffold protein muscle A-kinase anchoring protein beta orchestrates cardiac myocyte hypertrophic signaling required for the development of heart failure. Circ Heart Fail 7(4):663-72. [PubMed: 24812305]  [MGI Ref ID J:214288]

Kruithof BP; Xu J; Fritz DT; Cabral CS; Gaussin V; Rogers MB. 2011. An in vivo map of bone morphogenetic protein 2 post-transcriptional repression in the heart. Genesis 49(11):841-50. [PubMed: 21504044]  [MGI Ref ID J:178663]

Kuprash DV; Alimzhanov MB; Tumanov AV; Anderson AO; Pfeffer K; Nedospasov SA. 1999. TNF and lymphotoxin beta cooperate in the maintenance of secondary lymphoid tissue microarchitecture but not in the development of lymph nodes. J Immunol 163(12):6575-80. [PubMed: 10586051]  [MGI Ref ID J:58981]

La Marca R; Cerri F; Horiuchi K; Bachi A; Feltri ML; Wrabetz L; Blobel CP; Quattrini A; Salzer JL; Taveggia C. 2011. TACE (ADAM17) inhibits Schwann cell myelination. Nat Neurosci 14(7):857-65. [PubMed: 21666671]  [MGI Ref ID J:174007]

Labi V; Erlacher M; Kiessling S; Manzl C; Frenzel A; O'Reilly L; Strasser A; Villunger A. 2008. Loss of the BH3-only protein Bmf impairs B cell homeostasis and accelerates gamma irradiation-induced thymic lymphoma development. J Exp Med 205(3):641-55. [PubMed: 18299399]  [MGI Ref ID J:133084]

Labonte D; Thies E; Pechmann Y; Groffen AJ; Verhage M; Smit AB; van Kesteren RE; Kneussel M. 2013. TRIM3 regulates the motility of the kinesin motor protein KIF21B. PLoS One 8(9):e75603. [PubMed: 24086586]  [MGI Ref ID J:207738]

Lamming DW; Mihaylova MM; Katajisto P; Baar EL; Yilmaz OH; Hutchins A; Gultekin Y; Gaither R; Sabatini DM. 2014. Depletion of Rictor, an essential protein component of mTORC2, decreases male lifespan. Aging Cell 13(5):911-7. [PubMed: 25059582]  [MGI Ref ID J:215384]

Lang CH; Frost RA; Bronson SK; Lynch CJ; Vary TC. 2010. Skeletal muscle protein balance in mTOR heterozygous mice in response to inflammation and leucine. Am J Physiol Endocrinol Metab 298(6):E1283-94. [PubMed: 20388826]  [MGI Ref ID J:162945]

Lapointe E; Boyer A; Rico C; Paquet M; Franco HL; Gossen J; DeMayo FJ; Richards JS; Boerboom D. 2012. FZD1 regulates cumulus expansion genes and is required for normal female fertility in mice. Biol Reprod 87(5):104. [PubMed: 22954793]  [MGI Ref ID J:192479]

Lathrop MJ; Chakrabarti L; Eng J; Rhodes CH; Lutz T; Nieto A; Liggitt HD; Warner S; Fields J; Stoger R; Fiering S. 2010. Deletion of the Chd6 exon 12 affects motor coordination. Mamm Genome 21(3-4):130-42. [PubMed: 20111866]  [MGI Ref ID J:158513]

Latreille M; Hausser J; Stutzer I; Zhang Q; Hastoy B; Gargani S; Kerr-Conte J; Pattou F; Zavolan M; Esguerra JL; Eliasson L; Rulicke T; Rorsman P; Stoffel M. 2014. MicroRNA-7a regulates pancreatic beta cell function. J Clin Invest 124(6):2722-35. [PubMed: 24789908]  [MGI Ref ID J:212929]

Lederle W; Hartenstein B; Meides A; Kunzelmann H; Werb Z; Angel P; Mueller MM. 2010. MMP13 as a stromal mediator in controlling persistent angiogenesis in skin carcinoma. Carcinogenesis 31(7):1175-84. [PubMed: 19892798]  [MGI Ref ID J:161651]

Lehmann FM; Feicht S; Helm F; Maurberger A; Ladinig C; Zimber-Strobl U; Kuhn R; Mautner J; Gerbitz A; Bornkamm GW. 2012. Humanized c-Myc mouse. PLoS One 7(7):e42021. [PubMed: 22860051]  [MGI Ref ID J:189677]

LeibundGut-Landmann S; Waldburger JM; Reis e Sousa C; Acha-Orbea H; Reith W. 2004. MHC class II expression is differentially regulated in plasmacytoid and conventional dendritic cells. Nat Immunol 5(9):899-908. [PubMed: 15322541]  [MGI Ref ID J:92170]

Leipold E; Liebmann L; Korenke GC; Heinrich T; Giesselmann S; Baets J; Ebbinghaus M; Goral RO; Stodberg T; Hennings JC; Bergmann M; Altmuller J; Thiele H; Wetzel A; Nurnberg P; Timmerman V; De Jonghe P; Blum R; Schaible HG; Weis J; Heinemann SH; Hubner CA; Kurth I. 2013. A de novo gain-of-function mutation in SCN11A causes loss of pain perception. Nat Genet 45(11):1399-404. [PubMed: 24036948]  [MGI Ref ID J:206848]

Lewis AS; Vaidya SP; Blaiss CA; Liu Z; Stoub TR; Brager DH; Chen X; Bender RA; Estep CM; Popov AB; Kang CE; Van Veldhoven PP; Bayliss DA; Nicholson DA; Powell CM; Johnston D; Chetkovich DM. 2011. Deletion of the hyperpolarization-activated cyclic nucleotide-gated channel auxiliary subunit TRIP8b impairs hippocampal Ih localization and function and promotes antidepressant behavior in mice. J Neurosci 31(20):7424-40. [PubMed: 21593326]  [MGI Ref ID J:173355]

Li H; Rajendran GK; Liu N; Ware C; Rubin BP; Gu Y. 2007. SirT1 modulates the estrogen-insulin-like growth factor-1 signaling for postnatal development of mammary gland in mice. Breast Cancer Res 9(1):R1. [PubMed: 17201918]  [MGI Ref ID J:121948]

Li J; Goossens S; van Hengel J; Gao E; Cheng L; Tyberghein K; Shang X; De Rycke R; van Roy F; Radice GL. 2012. Loss of alphaT-catenin alters the hybrid adhering junctions in the heart and leads to dilated cardiomyopathy and ventricular arrhythmia following acute ischemia. J Cell Sci 125(Pt 4):1058-67. [PubMed: 22421363]  [MGI Ref ID J:197814]

Li J; Kritzer MD; Michel JJ; Le A; Thakur H; Gayanilo M; Passariello CL; Negro A; Danial JB; Oskouei B; Sanders M; Hare JM; Hanauer A; Dodge-Kafka K; Kapiloff MS. 2013. Anchored p90 ribosomal S6 kinase 3 is required for cardiac myocyte hypertrophy. Circ Res 112(1):128-39. [PubMed: 22997248]  [MGI Ref ID J:205403]

Li L; Bailey E; Greenblatt S; Huso D; Small D. 2011. Loss of the wild-type allele contributes to myeloid expansion and disease aggressiveness in FLT3/ITD knockin mice. Blood 118(18):4935-45. [PubMed: 21908433]  [MGI Ref ID J:178792]

Li S; Lu MM; Zhou D; Hammes SR; Morrisey EE. 2007. GLP-1: a novel zinc finger protein required in somatic cells of the gonad for germ cell development. Dev Biol 301(1):106-16. [PubMed: 16982049]  [MGI Ref ID J:116977]

Li ZH; Dulyaninova NG; House RP; Almo SC; Bresnick AR. 2010. S100A4 regulates macrophage chemotaxis. Mol Biol Cell 21(15):2598-610. [PubMed: 20519440]  [MGI Ref ID J:182865]

Lim P; Allan CM; Notini AJ; Axell AM; Spaliviero J; Jimenez M; Davey R; McManus J; MacLean HE; Zajac JD; Handelsman DJ. 2008. Oestradiol-induced spermatogenesis requires a functional androgen receptor. Reprod Fertil Dev 20(8):861-70. [PubMed: 19007549]  [MGI Ref ID J:154427]

Lim P; Robson M; Spaliviero J; McTavish KJ; Jimenez M; Zajac JD; Handelsman DJ; Allan CM. 2009. Sertoli cell androgen receptor DNA binding domain is essential for the completion of spermatogenesis. Endocrinology 150(10):4755-65. [PubMed: 19574395]  [MGI Ref ID J:157337]

Lin PP; Pandey MK; Jin F; Xiong S; Deavers M; Parant JM; Lozano G. 2008. EWS-FLI1 induces developmental abnormalities and accelerates sarcoma formation in a transgenic mouse model. Cancer Res 68(21):8968-75. [PubMed: 18974141]  [MGI Ref ID J:140636]

Liu C; Liu W; Palie J; Lu MF; Brown NA; Martin JF. 2002. Pitx2c patterns anterior myocardium and aortic arch vessels and is required for local cell movement into atrioventricular cushions. Development 129(21):5081-91. [PubMed: 12397115]  [MGI Ref ID J:79853]

Liu M; Sjogren AK; Karlsson C; Ibrahim MX; Andersson KM; Olofsson FJ; Wahlstrom AM; Dalin M; Yu H; Chen Z; Yang SH; Young SG; Bergo MO. 2010. Targeting the protein prenyltransferases efficiently reduces tumor development in mice with K-RAS-induced lung cancer. Proc Natl Acad Sci U S A 107(14):6471-6. [PubMed: 20308544]  [MGI Ref ID J:158937]

Liu X; Holstege H; van der Gulden H; Treur-Mulder M; Zevenhoven J; Velds A; Kerkhoven RM; van Vliet MH; Wessels LF; Peterse JL; Berns A; Jonkers J. 2007. Somatic loss of BRCA1 and p53 in mice induces mammary tumors with features of human BRCA1-mutated basal-like breast cancer. Proc Natl Acad Sci U S A 104(29):12111-6. [PubMed: 17626182]  [MGI Ref ID J:126551]

Lommel S; Benesch S; Rottner K; Franz T; Wehland J; Kuhn R. 2001. Actin pedestal formation by enteropathogenic Escherichia coli and intracellular motility of Shigella flexneri are abolished in N-WASP-defective cells. EMBO Rep 2(9):850-7. [PubMed: 11559594]  [MGI Ref ID J:73609]

Lopes Floro K; Artap ST; Preis JI; Fatkin D; Chapman G; Furtado MB; Harvey RP; Hamada H; Sparrow DB; Dunwoodie SL. 2011. Loss of Cited2 causes congenital heart disease by perturbing left-right patterning of the body axis. Hum Mol Genet 20(6):1097-110. [PubMed: 21224256]  [MGI Ref ID J:168841]

Lu LF; Gavin MA; Rasmussen JP; Rudensky AY. 2007. G protein-coupled receptor 83 is dispensable for the development and function of regulatory T cells. Mol Cell Biol 27(23):8065-72. [PubMed: 17893329]  [MGI Ref ID J:127791]

Lu R; Li Y; Zhang Y; Chen Y; Shields AD; Winder DG; Angelotti T; Jiao K; Limbird LE; Zhou Y; Wang Q. 2009. Epitope-tagged receptor knock-in mice reveal that differential desensitization of alpha2-adrenergic responses is because of ligand-selective internalization. J Biol Chem 284(19):13233-43. [PubMed: 19276088]  [MGI Ref ID J:149752]

Lubben W; Turqueti-Neves A; Okhrimenko A; Stoberl C; Schmidt V; Pfeffer K; Dehnert S; Wunsche S; Storsberg S; Paul S; Bauer S; Riethmuller G; Voehringer D; Yu P. 2013. IgE knock-in mice suggest a role for high levels of IgE in basophil-mediated active systemic anaphylaxis. Eur J Immunol 43(5):1231-42. [PubMed: 23423996]  [MGI Ref ID J:198154]

Luche H; Nageswara Rao T; Kumar S; Tasdogan A; Beckel F; Blum C; Martins VC; Rodewald HR; Fehling HJ. 2013. In vivo fate mapping identifies pre-TCRalpha expression as an intra- and extrathymic, but not prethymic, marker of T lymphopoiesis. J Exp Med 210(4):699-714. [PubMed: 23509324]  [MGI Ref ID J:197923]

Luche H; Weber O; Nageswara Rao T; Blum C; Fehling HJ. 2007. Faithful activation of an extra-bright red fluorescent protein in 'knock-in' Cre-reporter mice ideally suited for lineage tracing studies. Eur J Immunol 37(1):43-53. [PubMed: 17171761]  [MGI Ref ID J:117041]

Luckow B; Hanggli A; Maier H; Chilla S; Loewe RP; Dehmel S; Schlondorff D; Loetscher P; Zerwes HG; Muller M. 2009. Microinjection of Cre recombinase protein into zygotes enables specific deletion of two eukaryotic selection cassettes and enhances the expression of a DsRed2 reporter gene in Ccr2/Ccr5 double-deficient mice. Genesis 47(8):545-58. [PubMed: 19517561]  [MGI Ref ID J:152815]

Luedde T; Assmus U; Wustefeld T; Meyer Zu Vilsendorf A; Roskams T; Schmidt-Supprian M; Rajewsky K; Brenner DA; Manns MP; Pasparakis M; Trautwein C. 2005. Deletion of IKK2 in hepatocytes does not sensitize these cells to TNF-induced apoptosis but protects from ischemia/reperfusion injury. J Clin Invest 115(4):849-859. [PubMed: 15776110]  [MGI Ref ID J:97326]

Lutz C; Ledermann B; Kosco-Vilbois MH; Ochsenbein AF; Zinkernagel RM; Kohler G; Brombacher F. 1998. IgD can largely substitute for loss of IgM function in B cells. Nature 393(6687):797-801. [PubMed: 9655395]  [MGI Ref ID J:57600]

Ma X; Bao J; Adelstein RS. 2007. Loss of cell adhesion causes hydrocephalus in nonmuscle myosin II-B-ablated and mutated mice. Mol Biol Cell 18(6):2305-12. [PubMed: 17429076]  [MGI Ref ID J:127463]

Ma X; Kawamoto S; Hara Y; Adelstein RS. 2004. A point mutation in the motor domain of nonmuscle myosin II-B impairs migration of distinct groups of neurons. Mol Biol Cell 15(6):2568-79. [PubMed: 15034141]  [MGI Ref ID J:92081]

Ma X; Kawamoto S; Uribe J; Adelstein RS. 2006. Function of the neuron-specific alternatively spliced isoforms of nonmuscle myosin II-B during mouse brain development. Mol Biol Cell 17(5):2138-49. [PubMed: 16481398]  [MGI Ref ID J:112536]

Ma X; Renda MJ; Wang L; Cheng EC; Niu C; Morris SW; Chi AS; Krause DS. 2007. Rbm15 modulates Notch-induced transcriptional activation and affects myeloid differentiation. Mol Cell Biol 27(8):3056-64. [PubMed: 17283045]  [MGI Ref ID J:121406]

MacFarlane AJ; Liu X; Perry CA; Flodby P; Allen RH; Stabler SP; Stover PJ. 2008. Cytoplasmic serine hydroxymethyltransferase regulates the metabolic partitioning of methylenetetrahydrofolate but is not essential in mice. J Biol Chem 283(38):25846-53. [PubMed: 18644786]  [MGI Ref ID J:141998]

MacLean HE; Chiu WS; Notini AJ; Axell AM; Davey RA; McManus JF; Ma C; Plant DR; Lynch GS; Zajac JD. 2008. Impaired skeletal muscle development and function in male, but not female, genomic androgen receptor knockout mice. FASEB J 22(8):2676-89. [PubMed: 18390925]  [MGI Ref ID J:138008]

Macatee TL; Hammond BP; Arenkiel BR; Francis L; Frank DU; Moon AM. 2003. Ablation of specific expression domains reveals discrete functions of ectoderm- and endoderm-derived FGF8 during cardiovascular and pharyngeal development. Development 130(25):6361-74. [PubMed: 14623825]  [MGI Ref ID J:87304]

Madan B; Madan V; Weber O; Tropel P; Blum C; Kieffer E; Viville S; Fehling HJ. 2009. The pluripotency-associated gene Dppa4 is dispensable for embryonic stem cell identity and germ cell development but essential for embryogenesis. Mol Cell Biol 29(11):3186-203. [PubMed: 19332562]  [MGI Ref ID J:149143]

Madan V; Madan B; Brykczynska U; Zilbermann F; Hogeveen K; Dohner K; Dohner H; Weber O; Blum C; Rodewald HR; Sassone-Corsi P; Peters AH; Fehling HJ. 2009. Impaired function of primitive hematopoietic cells in mice lacking the Mixed-Lineage-Leukemia homolog MLL5. Blood 113(7):1444-54. [PubMed: 18952892]  [MGI Ref ID J:145579]

Maeda K; Kobayashi Y; Udagawa N; Uehara S; Ishihara A; Mizoguchi T; Kikuchi Y; Takada I; Kato S; Kani S; Nishita M; Marumo K; Martin TJ; Minami Y; Takahashi N. 2012. Wnt5a-Ror2 signaling between osteoblast-lineage cells and osteoclast precursors enhances osteoclastogenesis. Nat Med 18(3):405-12. [PubMed: 22344299]  [MGI Ref ID J:181641]

Magill ST; Cambronne XA; Luikart BW; Lioy DT; Leighton BH; Westbrook GL; Mandel G; Goodman RH. 2010. microRNA-132 regulates dendritic growth and arborization of newborn neurons in the adult hippocampus. Proc Natl Acad Sci U S A 107(47):20382-7. [PubMed: 21059906]  [MGI Ref ID J:166596]

Magnan A; Di Bartolo V; Mura AM; Boyer C; Richelme M; Lin YL; Roure A; Gillet A; Arrieumerlou C; Acuto O; Malissen B; Malissen M. 2001. T cell development and T cell responses in mice with mutations affecting tyrosines 292 or 315 of the ZAP-70 protein tyrosine kinase. J Exp Med 194(4):491-505. [PubMed: 11514605]  [MGI Ref ID J:71099]

Maina F; Pante G; Helmbacher F; Andres R; Porthin A; Davies AM; Ponzetto C; Klein R. 2001. Coupling Met to specific pathways results in distinct developmental outcomes. Mol Cell 7(6):1293-306. [PubMed: 11430831]  [MGI Ref ID J:94030]

Manchado E; Guillamot M; de Carcer G; Eguren M; Trickey M; Garcia-Higuera I; Moreno S; Yamano H; Canamero M; Malumbres M. 2010. Targeting mitotic exit leads to tumor regression in vivo: Modulation by Cdk1, Mastl, and the PP2A/B55alpha,delta phosphatase. Cancer Cell 18(6):641-54. [PubMed: 21156286]  [MGI Ref ID J:167609]

Mandai K; Guo T; St Hillaire C; Meabon JS; Kanning KC; Bothwell M; Ginty DD. 2009. LIG family receptor tyrosine kinase-associated proteins modulate growth factor signals during neural development. Neuron 63(5):614-27. [PubMed: 19755105]  [MGI Ref ID J:154926]

Marazziti D; Di Pietro C; Golini E; Mandillo S; La Sala G; Matteoni R; Tocchini-Valentini GP. 2013. Precocious cerebellum development and improved motor functions in mice lacking the astrocyte cilium-, patched 1-associated Gpr37l1 receptor. Proc Natl Acad Sci U S A 110(41):16486-16491. [PubMed: 24062445]  [MGI Ref ID J:201190]

Marino S; Krimpenfort P; Leung C; van der Korput HA; Trapman J; Camenisch I; Berns A; Brandner S. 2002. PTEN is essential for cell migration but not for fate determination and tumourigenesis in the cerebellum. Development 129(14):3513-22. [PubMed: 12091320]  [MGI Ref ID J:77123]

Marion V; Sankaranarayanan S; de Theije C; van Dijk P; Hakvoort TB; Lamers WH; Kohler ES. 2013. Hepatic adaptation compensates inactivation of intestinal arginine biosynthesis in suckling mice. PLoS One 8(6):e67021. [PubMed: 23785515]  [MGI Ref ID J:203474]

Marsicano G; Wotjak CT; Azad SC; Bisogno T; Rammes G; Cascio MG; Hermann H; Tang J; Hofmann C; Zieglgansberger W; Di Marzo V; Lutz B. 2002. The endogenous cannabinoid system controls extinction of aversive memories. Nature 418(6897):530-4. [PubMed: 12152079]  [MGI Ref ID J:77936]

Martens S; Parvanova I; Zerrahn J; Griffiths G; Schell G; Reichmann G; Howard JC. 2005. Disruption of Toxoplasma gondii parasitophorous vacuoles by the mouse p47-resistance GTPases. PLoS Pathog 1(3):e24. [PubMed: 16304607]  [MGI Ref ID J:135070]

Maruyama M; Lam KP; Rajewsky K. 2000. Memory B-cell persistence is independent of persisting immunizing antigen. Nature 407(6804):636-42. [PubMed: 11034213]  [MGI Ref ID J:111654]

Matsuoka RL; Chivatakarn O; Badea TC; Samuels IS; Cahill H; Katayama K; Kumar SR; Suto F; Chedotal A; Peachey NS; Nathans J; Yoshida Y; Giger RJ; Kolodkin AL. 2011. Class 5 transmembrane semaphorins control selective Mammalian retinal lamination and function. Neuron 71(3):460-73. [PubMed: 21835343]  [MGI Ref ID J:174679]

Matsushima S; Kuroda J; Ago T; Zhai P; Ikeda Y; Oka S; Fong GH; Tian R; Sadoshima J. 2013. Broad suppression of NADPH oxidase activity exacerbates ischemia/reperfusion injury through inadvertent downregulation of hypoxia-inducible factor-1alpha and upregulation of peroxisome proliferator-activated receptor-alpha. Circ Res 112(8):1135-49. [PubMed: 23476056]  [MGI Ref ID J:213317]

Mc Guire C; Volckaert T; Wolke U; Sze M; de Rycke R; Waisman A; Prinz M; Beyaert R; Pasparakis M; van Loo G. 2010. Oligodendrocyte-specific FADD deletion protects mice from autoimmune-mediated demyelination. J Immunol 185(12):7646-53. [PubMed: 21068410]  [MGI Ref ID J:167475]

McKernan RM; Rosahl TW; Reynolds DS; Sur C; Wafford KA; Atack JR; Farrar S; Myers J; Cook G; Ferris P; Garrett L; Bristow L; Marshall G; Macaulay A; Brown N; Howell O; Moore KW; Carling RW; Street LJ; Castro JL; Ragan CI; Dawson GR; Whiting PJ. 2000. Sedative but not anxiolytic properties of benzodiazepines are mediated by the GABA(A) receptor alpha1 subtype [see comments] Nat Neurosci 3(6):587-92. [PubMed: 10816315]  [MGI Ref ID J:62214]

Meier ID; Bernreuther C; Tilling T; Neidhardt J; Wong YW; Schulze C; Streichert T; Schachner M. 2010. Short DNA sequences inserted for gene targeting can accidentally interfere with off-target gene expression. FASEB J 24(6):1714-24. [PubMed: 20110269]  [MGI Ref ID J:162048]

Mende Y; Jakubik M; Riessland M; Schoenen F; Rossbach K; Kleinridders A; Kohler C; Buch T; Wirth B. 2010. Deficiency of the splicing factor Sfrs10 results in early embryonic lethality in mice and has no impact on full-length SMN/Smn splicing. Hum Mol Genet 19(11):2154-67. [PubMed: 20190275]  [MGI Ref ID J:159448]

Mercer K; Giblett S; Green S; Lloyd D; Darocha Dias S; Plumb M; Marais R; Pritchard C. 2005. Expression of endogenous oncogenic V600EB-raf induces proliferation and developmental defects in mice and transformation of primary fibroblasts. Cancer Res 65(24):11493-500. [PubMed: 16357158]  [MGI Ref ID J:104375]

Merkwirth C; Dargazanli S; Tatsuta T; Geimer S; Lower B; Wunderlich FT; von Kleist-Retzow JC; Waisman A; Westermann B; Langer T. 2008. Prohibitins control cell proliferation and apoptosis by regulating OPA1-dependent cristae morphogenesis in mitochondria. Genes Dev 22(4):476-88. [PubMed: 18281461]  [MGI Ref ID J:131699]

Michos O; Goncalves A; Lopez-Rios J; Tiecke E; Naillat F; Beier K; Galli A; Vainio S; Zeller R. 2007. Reduction of BMP4 activity by gremlin 1 enables ureteric bud outgrowth and GDNF/WNT11 feedback signalling during kidney branching morphogenesis. Development 134(13):2397-405. [PubMed: 17522159]  [MGI Ref ID J:122530]

Mikolcevic P; Sigl R; Rauch V; Hess MW; Pfaller K; Barisic M; Pelliniemi LJ; Boesl M; Geley S. 2012. Cyclin-dependent kinase 16/PCTAIRE kinase 1 is activated by cyclin Y and is essential for spermatogenesis. Mol Cell Biol 32(4):868-79. [PubMed: 22184064]  [MGI Ref ID J:183637]

Miller NL; Lawson C; Chen XL; Lim ST; Schlaepfer DD. 2012. Rgnef (p190RhoGEF) knockout inhibits RhoA activity, focal adhesion establishment, and cell motility downstream of integrins. PLoS One 7(5):e37830. [PubMed: 22649559]  [MGI Ref ID J:221026]

Minichiello L; Calella AM; Medina DL; Bonhoeffer T; Klein R; Korte M. 2002. Mechanism of TrkB-mediated hippocampal long-term potentiation. Neuron 36(1):121-37. [PubMed: 12367511]  [MGI Ref ID J:130626]

Mizuno K; Ris L; Sanchez-Capelo A; Godaux E; Giese KP. 2006. Ca2+/calmodulin kinase kinase alpha is dispensable for brain development but is required for distinct memories in male, though not in female, mice. Mol Cell Biol 26(23):9094-104. [PubMed: 17015468]  [MGI Ref ID J:117629]

Moulin M; Anderton H; Voss AK; Thomas T; Wong WW; Bankovacki A; Feltham R; Chau D; Cook WD; Silke J; Vaux DL. 2012. IAPs limit activation of RIP kinases by TNF receptor 1 during development. EMBO J 31(7):1679-91. [PubMed: 22327219]  [MGI Ref ID J:182515]

Moussa O; LaRue AC; Abangan RS Jr; Williams CR; Zhang XK; Masuya M; Gong YZ; Spyropoulos DD; Ogawa M; Gilkeson G; Watson DK. 2010. Thrombocytopenia in mice lacking the carboxy-terminal regulatory domain of the Ets transcription factor Fli1. Mol Cell Biol 30(21):5194-206. [PubMed: 20823267]  [MGI Ref ID J:203977]

Mu X; Fu X; Beremand PD; Thomas TL; Klein WH. 2008. Gene regulation logic in retinal ganglion cell development: Isl1 defines a critical branch distinct from but overlapping with Pou4f2. Proc Natl Acad Sci U S A 105(19):6942-7. [PubMed: 18460603]  [MGI Ref ID J:146349]

Muller MR; Sasaki Y; Stevanovic I; Lamperti ED; Ghosh S; Sharma S; Gelinas C; Rossi DJ; Pipkin ME; Rajewsky K; Hogan PG; Rao A. 2009. Requirement for balanced Ca/NFAT signaling in hematopoietic and embryonic development. Proc Natl Acad Sci U S A 106(17):7034-9. [PubMed: 19351896]  [MGI Ref ID J:148341]

Murphy JM; Czabotar PE; Hildebrand JM; Lucet IS; Zhang JG; Alvarez-Diaz S; Lewis R; Lalaoui N; Metcalf D; Webb AI; Young SN; Varghese LN; Tannahill GM; Hatchell EC; Majewski IJ; Okamoto T; Dobson RC; Hilton DJ; Babon JJ; Nicola NA; Strasser A; Silke J; Alexander WS. 2013. The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism. Immunity 39(3):443-53. [PubMed: 24012422]  [MGI Ref ID J:204620]

Murtaugh LC; Law AC; Dor Y; Melton DA. 2005. Beta-catenin is essential for pancreatic acinar but not islet development. Development 132(21):4663-74. [PubMed: 16192304]  [MGI Ref ID J:102698]

Naetar N; Korbei B; Kozlov S; Kerenyi MA; Dorner D; Kral R; Gotic I; Fuchs P; Cohen TV; Bittner R; Stewart CL; Foisner R. 2008. Loss of nucleoplasmic LAP2alpha-lamin A complexes causes erythroid and epidermal progenitor hyperproliferation. Nat Cell Biol 10(11):1341-8. [PubMed: 18849980]  [MGI Ref ID J:145628]

Nakakura T; Mogi C; Tobo M; Tomura H; Sato K; Kobayashi M; Ohnishi H; Tanaka S; Wayama M; Sugiyama T; Kitamura T; Harada A; Okajima F. 2012. Deficiency of proton-sensing ovarian cancer G protein-coupled receptor 1 attenuates glucose-stimulated insulin secretion. Endocrinology 153(9):4171-80. [PubMed: 22733973]  [MGI Ref ID J:189192]

Nanda N; Iismaa SE; Owens WA; Husain A; Mackay F; Graham RM. 2001. Targeted inactivation of Gh/tissue transglutaminase II. J Biol Chem 276(23):20673-8. [PubMed: 11274171]  [MGI Ref ID J:95130]

Nassar MA; Baker MD; Levato A; Ingram R; Mallucci G; McMahon SB; Wood JN. 2006. Nerve injury induces robust allodynia and ectopic discharges in Nav1.3 null mutant mice. Mol Pain 2:33. [PubMed: 17052333]  [MGI Ref ID J:199857]

Nemazanyy I; Blaauw B; Paolini C; Caillaud C; Protasi F; Mueller A; Proikas-Cezanne T; Russell RC; Guan KL; Nishino I; Sandri M; Pende M; Panasyuk G. 2013. Defects of Vps15 in skeletal muscles lead to autophagic vacuolar myopathy and lysosomal disease. EMBO Mol Med 5(6):870-90. [PubMed: 23630012]  [MGI Ref ID J:198770]

Ng AP; Kauppi M; Metcalf D; Hyland CD; Josefsson EC; Lebois M; Zhang JG; Baldwin TM; Di Rago L; Hilton DJ; Alexander WS. 2014. Mpl expression on megakaryocytes and platelets is dispensable for thrombopoiesis but essential to prevent myeloproliferation. Proc Natl Acad Sci U S A 111(16):5884-9. [PubMed: 24711413]  [MGI Ref ID J:208120]

Nie X; Xu J; El-Hashash A; Xu PX. 2011. Six1 regulates Grem1 expression in the metanephric mesenchyme to initiate branching morphogenesis. Dev Biol 352(1):141-51. [PubMed: 21281623]  [MGI Ref ID J:171473]

Noben-Trauth N; Kohler G; Burki K; Ledermann B. 1996. Efficient targeting of the IL-4 gene in a BALB/c embryonic stem cell line. Transgenic Res 5(6):487-91. [PubMed: 8840532]  [MGI Ref ID J:36386]

Noble C; Mercer K; Hussain J; Carragher L; Giblett S; Hayward R; Patterson C; Marais R; Pritchard CA. 2008. CRAF autophosphorylation of serine 621 is required to prevent its proteasome-mediated degradation. Mol Cell 31(6):862-72. [PubMed: 18922468]  [MGI Ref ID J:141095]

North BJ; Rosenberg MA; Jeganathan KB; Hafner AV; Michan S; Dai J; Baker DJ; Cen Y; Wu LE; Sauve AA; van Deursen JM; Rosenzweig A; Sinclair DA. 2014. SIRT2 induces the checkpoint kinase BubR1 to increase lifespan. EMBO J 33(13):1438-53. [PubMed: 24825348]  [MGI Ref ID J:211655]

Notari M; Hu Y; Koch S; Lu M; Ratnayaka I; Zhong S; Baer C; Pagotto A; Goldin R; Salter V; Candi E; Melino G; Lu X. 2011. Inhibitor of apoptosis-stimulating protein of p53 (iASPP) prevents senescence and is required for epithelial stratification. Proc Natl Acad Sci U S A 108(40):16645-50. [PubMed: 21930934]  [MGI Ref ID J:177360]

Notini AJ; Davey RA; McManus JF; Bate KL; Zajac JD. 2005. Genomic actions of the androgen receptor are required for normal male sexual differentiation in a mouse model. J Mol Endocrinol 35(3):547-55. [PubMed: 16326839]  [MGI Ref ID J:123057]

Novarino G; Weinert S; Rickheit G; Jentsch TJ. 2010. Endosomal chloride-proton exchange rather than chloride conductance is crucial for renal endocytosis. Science 328(5984):1398-401. [PubMed: 20430975]  [MGI Ref ID J:160701]

Nukaya M; Moran S; Bradfield CA. 2009. The role of the dioxin-responsive element cluster between the Cyp1a1 and Cyp1a2 loci in aryl hydrocarbon receptor biology. Proc Natl Acad Sci U S A 106(12):4923-8. [PubMed: 19261855]  [MGI Ref ID J:147150]

Nunez-Cruz S; Aguado E; Richelme S; Chetaille B; Mura AM; Richelme M; Pouyet L; Jouvin-Marche E; Xerri L; Malissen B; Malissen M. 2003. LAT regulates gammadelta T cell homeostasis and differentiation. Nat Immunol 4(10):999-1008. [PubMed: 12970761]  [MGI Ref ID J:94074]

O' Reilly LA; Tai L; Lee L; Kruse EA; Grabow S; Fairlie WD; Haynes NM; Tarlinton DM; Zhang JG; Belz GT; Smyth MJ; Bouillet P; Robb L; Strasser A. 2009. Membrane-bound Fas ligand only is essential for Fas-induced apoptosis. Nature 461(7264):659-63. [PubMed: 19794494]  [MGI Ref ID J:153501]

Oh-Hora M; Komatsu N; Pishyareh M; Feske S; Hori S; Taniguchi M; Rao A; Takayanagi H. 2013. Agonist-selected T cell development requires strong T cell receptor signaling and store-operated calcium entry. Immunity 38(5):881-95. [PubMed: 23499491]  [MGI Ref ID J:203161]

Oh-Hora M; Yamashita M; Hogan PG; Sharma S; Lamperti E; Chung W; Prakriya M; Feske S; Rao A. 2008. Dual functions for the endoplasmic reticulum calcium sensors STIM1 and STIM2 in T cell activation and tolerance. Nat Immunol 9(4):432-43. [PubMed: 18327260]  [MGI Ref ID J:133262]

Ohinata Y; Payer B; O'Carroll D; Ancelin K; Ono Y; Sano M; Barton SC; Obukhanych T; Nussenzweig M; Tarakhovsky A; Saitou M; Surani MA. 2005. Blimp1 is a critical determinant of the germ cell lineage in mice. Nature 436(7048):207-13. [PubMed: 15937476]  [MGI Ref ID J:99994]

Ohyama T; Mohamed OA; Taketo MM; Dufort D; Groves AK. 2006. Wnt signals mediate a fate decision between otic placode and epidermis. Development 133(5):865-75. [PubMed: 16452098]  [MGI Ref ID J:105983]

Olswang Y; Cohen H; Papo O; Cassuto H; Croniger CM; Hakimi P; Tilghman SM; Hanson RW; Reshef L. 2002. A mutation in the peroxisome proliferator-activated receptor gamma-binding site in the gene for the cytosolic form of phosphoenolpyruvate carboxykinase reduces adipose tissue size and fat content in mice. Proc Natl Acad Sci U S A 99(2):625-30. [PubMed: 11792850]  [MGI Ref ID J:73977]

Ouyang W; Liao W; Luo CT; Yin N; Huse M; Kim MV; Peng M; Chan P; Ma Q; Mo Y; Meijer D; Zhao K; Rudensky AY; Atwal G; Zhang MQ; Li MO. 2012. Novel Foxo1-dependent transcriptional programs control T(reg) cell function. Nature 491(7425):554-9. [PubMed: 23135404]  [MGI Ref ID J:189962]

Painsipp E; Wultsch T; Edelsbrunner ME; Tasan RO; Singewald N; Herzog H; Holzer P. 2008. Reduced anxiety-like and depression-related behavior in neuropeptide Y Y4 receptor knockout mice. Genes Brain Behav 7(5):532-42. [PubMed: 18221379]  [MGI Ref ID J:150104]

Palmer S; Groves N; Schindeler A; Yeoh T; Biben C; Wang CC; Sparrow DB; Barnett L; Jenkins NA; Copeland NG; Koentgen F; Mohun T; Harvey RP. 2001. The small muscle-specific protein Csl modifies cell shape and promotes myocyte fusion in an insulin-like growth factor 1-dependent manner. J Cell Biol 153(5):985-98. [PubMed: 11381084]  [MGI Ref ID J:69803]

Palmer SJ; Santucci N; Widagdo J; Bontempo SJ; Taylor KM; Tay ES; Hook J; Lemckert F; Gunning PW; Hardeman EC. 2010. Negative autoregulation of GTF2IRD1 in Williams-Beuren syndrome via a novel DNA binding mechanism. J Biol Chem 285(7):4715-24. [PubMed: 20007321]  [MGI Ref ID J:159762]

Park U; Vastani N; Guan Y; Raja SN; Koltzenburg M; Caterina MJ. 2011. TRP vanilloid 2 knock-out mice are susceptible to perinatal lethality but display normal thermal and mechanical nociception. J Neurosci 31(32):11425-36. [PubMed: 21832173]  [MGI Ref ID J:175977]

Parsa S; Kuremoto K; Seidel K; Tabatabai R; Mackenzie B; Yamaza T; Akiyama K; Branch J; Koh CJ; Al Alam D; Klein OD; Bellusci S. 2010. Signaling by FGFR2b controls the regenerative capacity of adult mouse incisors. Development 137(22):3743-52. [PubMed: 20978072]  [MGI Ref ID J:167068]

Parsa S; Ramasamy SK; De Langhe S; Gupte VV; Haigh JJ; Medina D; Bellusci S. 2008. Terminal end bud maintenance in mammary gland is dependent upon FGFR2b signaling. Dev Biol 317(1):121-31. [PubMed: 18381212]  [MGI Ref ID J:136174]

Pasparakis M; Schmidt-Supprian M; Rajewsky K. 2002. IkappaB kinase signaling is essential for maintenance of mature B cells. J Exp Med 196(6):743-52. [PubMed: 12235208]  [MGI Ref ID J:79132]

Patterson HC; Kraus M; Kim YM; Ploegh H; Rajewsky K. 2006. The B cell receptor promotes B cell activation and proliferation through a non-ITAM tyrosine in the Igalpha cytoplasmic domain. Immunity 25(1):55-65. [PubMed: 16860757]  [MGI Ref ID J:113407]

Peckl-Schmid D; Wolkerstorfer S; Konigsberger S; Achatz-Straussberger G; Feichtner S; Schwaiger E; Zaborsky N; Huemer M; Gratz IK; Schibli R; Lamers M; Crameri R; Moser K; Luger EO; Achatz G. 2010. HAX1 deficiency: impact on lymphopoiesis and B-cell development. Eur J Immunol 40(11):3161-72. [PubMed: 20865787]  [MGI Ref ID J:174159]

Perea-Gomez A; Vella FD; Shawlot W; Oulad-Abdelghani M; Chazaud C; Meno C; Pfister V; Chen L; Robertson E; Hamada H; Behringer RR; Ang SL. 2002. Nodal antagonists in the anterior visceral endoderm prevent the formation of multiple primitive streaks. Dev Cell 3(5):745-56. [PubMed: 12431380]  [MGI Ref ID J:81339]

Pereverzev A; Mikhna M; Vajna R; Gissel C; Henry M; Weiergraber M; Hescheler J; Smyth N; Schneider T. 2002. Disturbances in glucose-tolerance, insulin-release, and stress-induced hyperglycemia upon disruption of the Ca(v)2.3 (alpha 1E) subunit of voltage-gated Ca(2+) channels. Mol Endocrinol 16(4):884-95. [PubMed: 11923483]  [MGI Ref ID J:95636]

Pereverzev A; Salehi A; Mikhna M; Renstrom E; Hescheler J; Weiergraber M; Smyth N; Schneider T. 2005. The ablation of the Ca(v)2.3/E-type voltage-gated Ca2+ channel causes a mild phenotype despite an altered glucose induced glucagon response in isolated islets of Langerhans. Eur J Pharmacol 511(1):65-72. [PubMed: 15777780]  [MGI Ref ID J:101873]

Petzold KM; Naumann H; Spagnoli FM. 2013. Rho signalling restriction by the RhoGAP Stard13 integrates growth and morphogenesis in the pancreas. Development 140(1):126-35. [PubMed: 23175628]  [MGI Ref ID J:191071]

Polak P; Cybulski N; Feige JN; Auwerx J; Ruegg MA; Hall MN. 2008. Adipose-specific knockout of raptor results in lean mice with enhanced mitochondrial respiration. Cell Metab 8(5):399-410. [PubMed: 19046571]  [MGI Ref ID J:143749]

Polli M; Dakic A; Light A; Wu L; Tarlinton DM; Nutt SL. 2005. The development of functional B lymphocytes in conditional PU.1 knock-out mice. Blood 106(6):2083-90. [PubMed: 15933053]  [MGI Ref ID J:118870]

Porubsky S; Speak AO; Luckow B; Cerundolo V; Platt FM; Grone HJ. 2007. Normal development and function of invariant natural killer T cells in mice with isoglobotrihexosylceramide (iGb3) deficiency. Proc Natl Acad Sci U S A 104(14):5977-82. [PubMed: 17372206]  [MGI Ref ID J:120323]

Porubsky S; Speak AO; Salio M; Jennemann R; Bonrouhi M; Zafarulla R; Singh Y; Dyson J; Luckow B; Lehuen A; Malle E; Muthing J; Platt FM; Cerundolo V; Grone HJ. 2012. Globosides but not isoglobosides can impact the development of invariant NKT cells and their interaction with dendritic cells. J Immunol 189(6):3007-17. [PubMed: 22875802]  [MGI Ref ID J:189359]

Poulos MG; Batra R; Li M; Yuan Y; Zhang C; Darnell RB; Swanson MS. 2013. Progressive impairment of muscle regeneration in muscleblind-like 3 isoform knockout mice. Hum Mol Genet 22(17):3547-58. [PubMed: 23660517]  [MGI Ref ID J:199127]

Prchal-Murphy M; Semper C; Lassnig C; Wallner B; Gausterer C; Teppner-Klymiuk I; Kobolak J; Muller S; Kolbe T; Karaghiosoff M; Dinnyes A; Rulicke T; Leitner NR; Strobl B; Muller M. 2012. TYK2 kinase activity is required for functional type I interferon responses in vivo. PLoS One 7(6):e39141. [PubMed: 22723949]  [MGI Ref ID J:187818]

Preis JI; Wise N; Solloway MJ; Harvey RP; Sparrow DB; Dunwoodie SL. 2006. Generation of conditional Cited2 null alleles. Genesis 44(12):579-83. [PubMed: 17133411]  [MGI Ref ID J:117087]

Preston P; Wartosch L; Gunzel D; Fromm M; Kongsuphol P; Ousingsawat J; Kunzelmann K; Barhanin J; Warth R; Jentsch TJ. 2010. Disruption of the K+ channel beta-subunit KCNE3 reveals an important role in intestinal and tracheal Cl- transport. J Biol Chem 285(10):7165-75. [PubMed: 20051516]  [MGI Ref ID J:160721]

Qin Y; Deng Y; Ricketts CJ; Srikantan S; Wang E; Maher ER; Dahia PL. 2014. The tumor susceptibility gene TMEM127 is mutated in renal cell carcinomas and modulates endolysosomal function. Hum Mol Genet 23(9):2428-39. [PubMed: 24334765]  [MGI Ref ID J:209071]

Ragancokova D; Rocca E; Oonk AM; Schulz H; Rohde E; Bednarsch J; Feenstra I; Pennings RJ; Wende H; Garratt AN. 2014. TSHZ1-dependent gene regulation is essential for olfactory bulb development and olfaction. J Clin Invest 124(3):1214-27. [PubMed: 24487590]  [MGI Ref ID J:209428]

Rahim MM; Tai LH; Troke AD; Mahmoud AB; Abou-Samra E; Roy JG; Mottashed A; Ault N; Corbeil C; Goulet ML; Zein HS; Hamilton-Valensky M; Krystal G; Kerr WG; Toyama-Sorimachi N; Makrigiannis AP. 2013. Ly49Q Positively Regulates Type I IFN Production by Plasmacytoid Dendritic Cells in an Immunoreceptor Tyrosine-Based Inhibitory Motif-Dependent Manner. J Immunol 190(8):3994-4004. [PubMed: 23479228]  [MGI Ref ID J:194900]

Rainbow DB; Moule C; Fraser HI; Clark J; Howlett SK; Burren O; Christensen M; Moody V; Steward CA; Mohammed JP; Fusakio ME; Masteller EL; Finger EB; Houchins JP; Naf D; Koentgen F; Ridgway WM; Todd JA; Bluestone JA; Peterson LB; Mattner J; Wicker LS. 2011. Evidence that Cd101 is an autoimmune diabetes gene in nonobese diabetic mice. J Immunol 187(1):325-36. [PubMed: 21613616]  [MGI Ref ID J:175943]

Ramanan N; Shen Y; Sarsfield S; Lemberger T; Schutz G; Linden DJ; Ginty DD. 2005. SRF mediates activity-induced gene expression and synaptic plasticity but not neuronal viability. Nat Neurosci 8(6):759-67. [PubMed: 15880109]  [MGI Ref ID J:99232]

Rana K; Fam BC; Clarke MV; Pang TP; Zajac JD; MacLean HE. 2011. Increased adiposity in DNA binding-dependent androgen receptor knockout male mice associated with decreased voluntary activity and not insulin resistance. Am J Physiol Endocrinol Metab 301(5):E767-78. [PubMed: 21712531]  [MGI Ref ID J:182193]

Rasmussen KD; Simmini S; Abreu-Goodger C; Bartonicek N; Di Giacomo M; Bilbao-Cortes D; Horos R; Von Lindern M; Enright AJ; O'Carroll D. 2010. The miR-144/451 locus is required for erythroid homeostasis. J Exp Med 207(7):1351-8. [PubMed: 20513743]  [MGI Ref ID J:163418]

Rawnsley DR; Xiao J; Lee JS; Liu X; Mericko-Ishizuka P; Kumar V; He J; Basu A; Lu M; Lynn FC; Pack M; Gasa R; Kahn ML. 2013. The transcription factor Atonal homolog 8 regulates Gata4 and Friend of Gata-2 during vertebrate development. J Biol Chem 288(34):24429-40. [PubMed: 23836893]  [MGI Ref ID J:203454]

Rebholz B; Haase I; Eckelt B; Paxian S; Flaig MJ; Ghoreschi K; Nedospasov SA; Mailhammer R; Debey-Pascher S; Schultze JL; Weindl G; Forster I; Huss R; Stratis A; Ruzicka T; Rocken M; Pfeffer K; Schmid RM; Rupec RA. 2007. Crosstalk between Keratinocytes and Adaptive Immune Cells in an IkappaBalpha Protein-Mediated Inflammatory Disease of the Skin. Immunity 27(2):296-307. [PubMed: 17692539]  [MGI Ref ID J:124343]

Reichert N; Wurster S; Ulrich T; Schmitt K; Hauser S; Probst L; Gotz R; Ceteci F; Moll R; Rapp U; Gaubatz S. 2010. Lin9, a subunit of the mammalian DREAM complex, is essential for embryonic development, for survival of adult mice, and for tumor suppression. Mol Cell Biol 30(12):2896-908. [PubMed: 20404087]  [MGI Ref ID J:162678]

Reuter M; Berninger P; Chuma S; Shah H; Hosokawa M; Funaya C; Antony C; Sachidanandam R; Pillai RS. 2011. Miwi catalysis is required for piRNA amplification-independent LINE1 transposon silencing. Nature 480(7376):264-7. [PubMed: 22121019]  [MGI Ref ID J:182800]

Revert-Ros F; Lopez-Pascual E; Granero-Molto F; Macias J; Breyer R; Zent R; Hudson BG; Saadeddin A; Revert F; Blasco R; Navarro C; Burks D; Saus J. 2011. Goodpasture antigen-binding protein (GPBP) directs myofibril formation: identification of intracellular downstream effector 130-kDa GPBP-interacting protein (GIP130). J Biol Chem 286(40):35030-43. [PubMed: 21832087]  [MGI Ref ID J:177789]

Rickheit G; Maier H; Strenzke N; Andreescu CE; De Zeeuw CI; Muenscher A; Zdebik AA; Jentsch TJ. 2008. Endocochlear potential depends on Cl- channels: mechanism underlying deafness in Bartter syndrome IV. EMBO J 27(21):2907-17. [PubMed: 18833191]  [MGI Ref ID J:143314]

Rickheit G; Wartosch L; Schaffer S; Stobrawa SM; Novarino G; Weinert S; Jentsch TJ. 2010. Role of ClC-5 in renal endocytosis is unique among ClC exchangers and does not require PY-motif-dependent ubiquitylation. J Biol Chem 285(23):17595-603. [PubMed: 20351103]  [MGI Ref ID J:164474]

Riegelhaupt JJ; Waase MP; Garbarino J; Cruz DE; Breslow JL. 2010. Targeted disruption of steroidogenic acute regulatory protein D4 leads to modest weight reduction and minor alterations in lipid metabolism. J Lipid Res 51(5):1134-43. [PubMed: 19965609]  [MGI Ref ID J:160807]

Rifat Y; Parekh V; Wilanowski T; Hislop NR; Auden A; Ting SB; Cunningham JM; Jane SM. 2010. Regional neural tube closure defined by the Grainy head-like transcription factors. Dev Biol 345(2):237-45. [PubMed: 20654612]  [MGI Ref ID J:164805]

Rocha PP; Bleiss W; Schrewe H. 2010. Mosaic expression of Med12 in female mice leads to exencephaly, spina bifida, and craniorachischisis. Birth Defects Res A Clin Mol Teratol 88(8):626-32. [PubMed: 20589884]  [MGI Ref ID J:166045]

Rodriguez-Diez E; Quereda V; Bellutti F; Prchal-Murphy M; Partida D; Eguren M; Kollmann K; Gomez de Cedron M; Dubus P; Canamero M; Martinez D; Sexl V; Malumbres M. 2014. Cdk4 and Cdk6 cooperate in counteracting the INK4 family of inhibitors during murine leukemogenesis. Blood 124(15):2380-90. [PubMed: 25157181]  [MGI Ref ID J:218704]

Roers A; Siewe L; Strittmatter E; Deckert M; Schluter D; Stenzel W; Gruber AD; Krieg T; Rajewsky K; Muller W. 2004. T cell-specific inactivation of the interleukin 10 gene in mice results in enhanced T cell responses but normal innate responses to lipopolysaccharide or skin irritation. J Exp Med 200(10):1289-97. [PubMed: 15534372]  [MGI Ref ID J:94537]

Rupec RA; Jundt F; Rebholz B; Eckelt B; Weindl G; Herzinger T; Flaig MJ; Moosmann S; Plewig G; Dorken B; Forster I; Huss R; Pfeffer K. 2005. Stroma-mediated dysregulation of myelopoiesis in mice lacking I kappa B alpha. Immunity 22(4):479-91. [PubMed: 15845452]  [MGI Ref ID J:97945]

Sainsbury A; Baldock PA; Schwarzer C; Ueno N; Enriquez RF; Couzens M; Inui A; Herzog H; Gardiner EM. 2003. Synergistic effects of Y2 and Y4 receptors on adiposity and bone mass revealed in double knockout mice. Mol Cell Biol 23(15):5225-33. [PubMed: 12861009]  [MGI Ref ID J:84570]

Sainsbury A; Schwarzer C; Couzens M; Fetissov S; Furtinger S; Jenkins A; Cox HM; Sperk G; Hokfelt T; Herzog H. 2002. Important role of hypothalamic Y2 receptors in body weight regulation revealed in conditional knockout mice. Proc Natl Acad Sci U S A 99(13):8938-43. [PubMed: 12072562]  [MGI Ref ID J:77345]

Sanchis-Segura C; Borchardt T; Vengeliene V; Zghoul T; Bachteler D; Gass P; Sprengel R; Spanagel R. 2006. Involvement of the AMPA receptor GluR-C subunit in alcohol-seeking behavior and relapse. J Neurosci 26(4):1231-8. [PubMed: 16436610]  [MGI Ref ID J:104146]

Sasaki Y; Casola S; Kutok JL; Rajewsky K; Schmidt-Supprian M. 2004. TNF family member B cell-activating factor (BAFF) receptor-dependent and -independent roles for BAFF in B cell physiology. J Immunol 173(4):2245-52. [PubMed: 15294936]  [MGI Ref ID J:92732]

Sato T; Iwano T; Kunii M; Matsuda S; Mizuguchi R; Jung Y; Hagiwara H; Yoshihara Y; Yuzaki M; Harada R; Harada A. 2014. Rab8a and Rab8b are essential for several apical transport pathways but insufficient for ciliogenesis. J Cell Sci 127(Pt 2):422-31. [PubMed: 24213529]  [MGI Ref ID J:211898]

Sato T; Mushiake S; Kato Y; Sato K; Sato M; Takeda N; Ozono K; Miki K; Kubo Y; Tsuji A; Harada R; Harada A. 2007. The Rab8 GTPase regulates apical protein localization in intestinal cells. Nature 448(7151):366-9. [PubMed: 17597763]  [MGI Ref ID J:123415]

Satpathy AT; Briseno CG; Lee JS; Ng D; Manieri NA; Kc W; Wu X; Thomas SR; Lee WL; Turkoz M; McDonald KG; Meredith MM; Song C; Guidos CJ; Newberry RD; Ouyang W; Murphy TL; Stappenbeck TS; Gommerman JL; Nussenzweig MC; Colonna M; Kopan R; Murphy KM. 2013. Notch2-dependent classical dendritic cells orchestrate intestinal immunity to attaching-and-effacing bacterial pathogens. Nat Immunol 14(9):937-48. [PubMed: 23913046]  [MGI Ref ID J:208234]

Schaefer A; Sampath SC; Intrator A; Min A; Gertler TS; Surmeier DJ; Tarakhovsky A; Greengard P. 2009. Control of cognition and adaptive behavior by the GLP/G9a epigenetic suppressor complex. Neuron 64(5):678-91. [PubMed: 20005824]  [MGI Ref ID J:155739]

Schaeper U; Vogel R; Chmielowiec J; Huelsken J; Rosario M; Birchmeier W. 2007. Distinct requirements for Gab1 in Met and EGF receptor signaling in vivo. Proc Natl Acad Sci U S A 104(39):15376-81. [PubMed: 17881575]  [MGI Ref ID J:125303]

Schenten D; Egert A; Pasparakis M; Rajewsky K. 2006. M17, a gene specific for germinal center (GC) B cells and a prognostic marker for GC B-cell lymphomas, is dispensable for the GC reaction in mice. Blood 107(12):4849-56. [PubMed: 16493007]  [MGI Ref ID J:125784]

Schenten D; Gerlach VL; Guo C; Velasco-Miguel S; Hladik CL; White CL; Friedberg EC; Rajewsky K; Esposito G. 2002. DNA polymerase kappa deficiency does not affect somatic hypermutation in mice. Eur J Immunol 32(11):3152-60. [PubMed: 12555660]  [MGI Ref ID J:80212]

Schenten D; Kracker S; Esposito G; Franco S; Klein U; Murphy M; Alt FW; Rajewsky K. 2009. Pol zeta ablation in B cells impairs the germinal center reaction, class switch recombination, DNA break repair, and genome stability. J Exp Med 206(2):477-90. [PubMed: 19204108]  [MGI Ref ID J:146453]

Schildknecht A; Welti S; Geuking MB; Hangartner L; van den Broek M. 2008. Absence of CTL Responses to Early Viral Antigens Facilitates Viral Persistence. J Immunol 180(5):3113-21. [PubMed: 18292534]  [MGI Ref ID J:131559]

Schlehe JS; Journel MS; Taylor KP; Amodeo KD; LaVoie MJ. 2013. The mitochondrial disease associated protein Ndufaf2 is dispensable for Complex-1 assembly but critical for the regulation of oxidative stress. Neurobiol Dis 58:57-67. [PubMed: 23702311]  [MGI Ref ID J:201547]

Schmid T; Gunther S; Mendler L; Braun T. 2013. Loss of NSCL-2 in gonadotropin releasing hormone neurons leads to reduction of pro-opiomelanocortin neurons in specific hypothalamic nuclei and causes visceral obesity. J Neurosci 33(25):10459-70. [PubMed: 23785158]  [MGI Ref ID J:199640]

Schmidt-Supprian M; Bloch W; Courtois G; Addicks K; Israel A; Rajewsky K; Pasparakis M. 2000. NEMO/IKK gamma-deficient mice model incontinentia pigmenti. Mol Cell 5(6):981-92. [PubMed: 10911992]  [MGI Ref ID J:63055]

Schmidt-Ullrich R; Aebischer T; Hulsken J; Birchmeier W; Klemm U; Scheidereit C. 2001. Requirement of NF-kappaB/Rel for the development of hair follicles and other epidermal appendices. Development 128(19):3843-53. [PubMed: 11585809]  [MGI Ref ID J:71744]

Schoggins JW; MacDuff DA; Imanaka N; Gainey MD; Shrestha B; Eitson JL; Mar KB; Richardson RB; Ratushny AV; Litvak V; Dabelic R; Manicassamy B; Aitchison JD; Aderem A; Elliott RM; Garcia-Sastre A; Racaniello V; Snijder EJ; Yokoyama WM; Diamond MS; Virgin HW; Rice CM. 2014. Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity. Nature 505(7485):691-5. [PubMed: 24284630]  [MGI Ref ID J:207826]

Schwab KR; Patterson LT; Hartman HA; Song N; Lang RA; Lin X; Potter SS. 2007. Pygo1 and Pygo2 roles in Wnt signaling in mammalian kidney development. BMC Biol 5:15. [PubMed: 17425782]  [MGI Ref ID J:121918]

Schwarz T; Remer KA; Nahrendorf W; Masic A; Siewe L; Muller W; Roers A; Moll H. 2013. T cell-derived IL-10 determines leishmaniasis disease outcome and is suppressed by a dendritic cell based vaccine. PLoS Pathog 9(6):e1003476. [PubMed: 23825956]  [MGI Ref ID J:213376]

Schwindinger WF; Mihalcik LJ; Giger KE; Betz KS; Stauffer AM; Linden J; Herve D; Robishaw JD. 2010. Adenosine A2A receptor signaling and golf assembly show a specific requirement for the gamma7 subtype in the striatum. J Biol Chem 285(39):29787-96. [PubMed: 20639202]  [MGI Ref ID J:166391]

Screen M; Dean W; Cross JC; Hemberger M. 2008. Cathepsin proteases have distinct roles in trophoblast function and vascular remodelling. Development 135(19):3311-20. [PubMed: 18776147]  [MGI Ref ID J:138768]

Seidl S; Braun U; Roos N; Li S; Ludtke TH; Kispert A; Leitges M. 2013. Phenotypical analysis of atypical PKCs in vivo function display a compensatory system at mouse embryonic day 7.5. PLoS One 8(5):e62756. [PubMed: 23690951]  [MGI Ref ID J:202124]

Seiler A; Schneider M; Forster H; Roth S; Wirth EK; Culmsee C; Plesnila N; Kremmer E; Radmark O; Wurst W; Bornkamm GW; Schweizer U; Conrad M. 2008. Glutathione peroxidase 4 senses and translates oxidative stress into 12/15-lipoxygenase dependent- and AIF-mediated cell death. Cell Metab 8(3):237-48. [PubMed: 18762024]  [MGI Ref ID J:139668]

Seitzer N; Mayr T; Streit S; Ullrich A. 2010. A single nucleotide change in the mouse genome accelerates breast cancer progression. Cancer Res 70(2):802-12. [PubMed: 20068154]  [MGI Ref ID J:156750]

Sekyere EO; Dunn LL; Rahmanto YS; Richardson DR. 2006. Role of melanotransferrin in iron metabolism: studies using targeted gene disruption in vivo. Blood 107(7):2599-601. [PubMed: 16291590]  [MGI Ref ID J:115256]

Seo KW. 2007. Dmrt2 and Pax3 double-knockout mice show severe defects in embryonic myogenesis. Comp Med 57(5):460-8. [PubMed: 17974128]  [MGI Ref ID J:142168]

Sergaki MC; Guillemot F; Matsas R. 2010. Impaired cerebellar development and deficits in motor coordination in mice lacking the neuronal protein BM88/Cend1. Mol Cell Neurosci 44(1):15-29. [PubMed: 20153830]  [MGI Ref ID J:164148]

Shi W; Bain AL; Schwer B; Al-Ejeh F; Smith C; Wong L; Chai H; Miranda MS; Ho U; Kawaguchi M; Miura Y; Finnie JW; Wall M; Heierhorst J; Wicking C; Spring KJ; Alt FW; Khanna KK. 2013. Essential developmental, genomic stability, and tumour suppressor functions of the mouse orthologue of hSSB1/NABP2. PLoS Genet 9(2):e1003298. [PubMed: 23408915]  [MGI Ref ID J:195140]

Shimshek DR; Jensen V; Celikel T; Geng Y; Schupp B; Bus T; Mack V; Marx V; Hvalby O; Seeburg PH; Sprengel R. 2006. Forebrain-specific glutamate receptor B deletion impairs spatial memory but not hippocampal field long-term potentiation. J Neurosci 26(33):8428-40. [PubMed: 16914668]  [MGI Ref ID J:111689]

Sieh P; Chen J. 2001. Distinct control of the frequency and allelic exclusion of the V beta gene rearrangement at the TCR beta locus. J Immunol 167(4):2121-9. [PubMed: 11489996]  [MGI Ref ID J:120387]

Sierro F; Biben C; Martinez-Munoz L; Mellado M; Ransohoff RM; Li M; Woehl B; Leung H; Groom J; Batten M; Harvey RP; Martinez-A C; Mackay CR; Mackay F. 2007. Disrupted cardiac development but normal hematopoiesis in mice deficient in the second CXCL12/SDF-1 receptor, CXCR7. Proc Natl Acad Sci U S A 104(37):14759-64. [PubMed: 17804806]  [MGI Ref ID J:124878]

Skelton MR; Schaefer TL; Graham DL; Degrauw TJ; Clark JF; Williams MT; Vorhees CV. 2011. Creatine transporter (CrT; Slc6a8) knockout mice as a model of human CrT deficiency. PLoS One 6(1):e16187. [PubMed: 21249153]  [MGI Ref ID J:169472]

Smink JJ; Begay V; Schoenmaker T; Sterneck E; de Vries TJ; Leutz A. 2009. Transcription factor C/EBPbeta isoform ratio regulates osteoclastogenesis through MafB. EMBO J 28(12):1769-81. [PubMed: 19440205]  [MGI Ref ID J:150006]

Somasundaram A; Shum AK; McBride HJ; Kessler JA; Feske S; Miller RJ; Prakriya M. 2014. Store-operated CRAC channels regulate gene expression and proliferation in neural progenitor cells. J Neurosci 34(27):9107-23. [PubMed: 24990931]  [MGI Ref ID J:212535]

Song L; Li Y; Wang K; Wang YZ; Molotkov A; Gao L; Zhao T; Yamagami T; Wang Y; Gan Q; Pleasure DE; Zhou CJ. 2009. Lrp6-mediated canonical Wnt signaling is required for lip formation and fusion. Development 136(18):3161-71. [PubMed: 19700620]  [MGI Ref ID J:152320]

Song N; Schwab KR; Patterson LT; Yamaguchi T; Lin X; Potter SS; Lang RA. 2007. pygopus 2 has a crucial, Wnt pathway-independent function in lens induction. Development 134(10):1873-85. [PubMed: 17428831]  [MGI Ref ID J:121416]

Song Y; Cygnar KD; Sagdullaev B; Valley M; Hirsh S; Stephan A; Reisert J; Zhao H. 2008. Olfactory CNG channel desensitization by Ca2+/CaM via the B1b subunit affects response termination but not sensitivity to recurring stimulation. Neuron 58(3):374-86. [PubMed: 18466748]  [MGI Ref ID J:145296]

Speer AL; Al Alam D; Sala FG; Ford HR; Bellusci S; Grikscheit TC. 2012. Fibroblast growth factor 10-fibroblast growth factor receptor 2b mediated signaling is not required for adult glandular stomach homeostasis. PLoS One 7(11):e49127. [PubMed: 23133671]  [MGI Ref ID J:195033]

Spohn G; Kleinridders A; Wunderlich FT; Watzka M; Zaucke F; Blumbach K; Geisen C; Seifried E; Muller C; Paulsson M; Bruning JC; Oldenburg J. 2009. VKORC1 deficiency in mice causes early postnatal lethality due to severe bleeding. Thromb Haemost 101(6):1044-50. [PubMed: 19492146]  [MGI Ref ID J:207884]

Staal B; Williams BO; Beier F; Vande Woude GF; Zhang YW. 2014. Cartilage-specific deletion of Mig-6 results in osteoarthritis-like disorder with excessive articular chondrocyte proliferation. Proc Natl Acad Sci U S A 111(7):2590-5. [PubMed: 24550287]  [MGI Ref ID J:206807]

Stadler HS; Higgins KM; Capecchi MR. 2001. Loss of Eph-receptor expression correlates with loss of cell adhesion and chondrogenic capacity in Hoxa13 mutant limbs. Development 128(21):4177-88. [PubMed: 11684655]  [MGI Ref ID J:72301]

Stadthagen G; Tehler D; Hoyland-Kroghsbo NM; Wen J; Krogh A; Jensen KT; Santoni-Rugiu E; Engelholm LH; Lund AH. 2013. Loss of miR-10a activates lpo and collaborates with activated Wnt signaling in inducing intestinal neoplasia in female mice. PLoS Genet 9(10):e1003913. [PubMed: 24204315]  [MGI Ref ID J:205135]

Staehli F; Ludigs K; Heinz LX; Seguin-Estevez Q; Ferrero I; Braun M; Schroder K; Rebsamen M; Tardivel A; Mattmann C; MacDonald HR; Romero P; Reith W; Guarda G; Tschopp J. 2012. NLRC5 deficiency selectively impairs MHC class I- dependent lymphocyte killing by cytotoxic T cells. J Immunol 188(8):3820-8. [PubMed: 22412192]  [MGI Ref ID J:184076]

Stan RV; Tse D; Deharvengt SJ; Smits NC; Xu Y; Luciano MR; McGarry CL; Buitendijk M; Nemani KV; Elgueta R; Kobayashi T; Shipman SL; Moodie KL; Daghlian CP; Ernst PA; Lee HK; Suriawinata AA; Schned AR; Longnecker DS; Fiering SN; Noelle RJ; Gimi B; ShworakNW; Carriere C. 2012. The diaphragms of fenestrated endothelia: gatekeepers of vascular permeability and blood composition. Dev Cell 23(6):1203-18. [PubMed: 23237953]  [MGI Ref ID J:191046]

Stanley EG; Biben C; Allison J; Hartley L; Wicks IP; Campbell IK; McKinley M; Barnett L; Koentgen F; Robb L; Harvey RP. 2000. Targeted insertion of a lacZ reporter gene into the mouse Cer1 locus reveals complex and dynamic expression during embryogenesis [letter] Genesis 26(4):259-64. [PubMed: 10748464]  [MGI Ref ID J:62081]

Stanton H; Rogerson FM; East CJ; Golub SB; Lawlor KE; Meeker CT; Little CB; Last K; Farmer PJ; Campbell IK; Fourie AM; Fosang AJ. 2005. ADAMTS5 is the major aggrecanase in mouse cartilage in vivo and in vitro. Nature 434(7033):648-52. [PubMed: 15800625]  [MGI Ref ID J:105138]

Starr R; Fuchsberger M; Lau LS; Uldrich AP; Goradia A; Willson TA; Verhagen AM; Alexander WS; Smyth MJ. 2009. SOCS-1 binding to tyrosine 441 of IFN-gamma receptor subunit 1 contributes to the attenuation of IFN-gamma signaling in vivo. J Immunol 183(7):4537-44. [PubMed: 19734231]  [MGI Ref ID J:152785]

Steinbrecher KA; Wowk SA; Rudolph JA; Witte DP; Cohen MB. 2002. Targeted inactivation of the mouse guanylin gene results in altered dynamics of colonic epithelial proliferation. Am J Pathol 161(6):2169-78. [PubMed: 12466132]  [MGI Ref ID J:80545]

Stemmler MP; Hecht A; Kemler R. 2005. E-cadherin intron 2 contains cis-regulatory elements essential for gene expression. Development 132(5):965-76. [PubMed: 15673570]  [MGI Ref ID J:96963]

Stennard FA; Costa MW; Lai D; Biben C; Furtado MB; Solloway MJ; McCulley DJ; Leimena C; Preis JI; Dunwoodie SL; Elliott DE; Prall OW; Black BL; Fatkin D; Harvey RP. 2005. Murine T-box transcription factor Tbx20 acts as a repressor during heart development, and is essential for adult heart integrity, function and adaptation. Development 132(10):2451-62. [PubMed: 15843414]  [MGI Ref ID J:98489]

Storch KF; Paz C; Signorovitch J; Raviola E; Pawlyk B; Li T; Weitz CJ. 2007. Intrinsic circadian clock of the Mammalian retina: importance for retinal processing of visual information. Cell 130(4):730-41. [PubMed: 17719549]  [MGI Ref ID J:124157]

Sugiyama F; Churchill GA; Higgins DC; Johns C; Makaritsis KP; Gavras H; Paigen B. 2001. Concordance of murine quantitative trait loci for salt-induced hypertension with rat and human loci. Genomics 71(1):70-7. [PubMed: 11161799]  [MGI Ref ID J:66987]

Suire S; Condliffe AM; Ferguson GJ; Ellson CD; Guillou H; Davidson K; Welch H; Coadwell J; Turner M; Chilvers ER; Hawkins PT; Stephens L. 2006. Gbetagammas and the Ras binding domain of p110gamma are both important regulators of PI(3)Kgamma signalling in neutrophils. Nat Cell Biol 8(11):1303-9. [PubMed: 17041586]  [MGI Ref ID J:147259]

Suire S; Lecureuil C; Anderson KE; Damoulakis G; Niewczas I; Davidson K; Guillou H; Pan D; Clark J; Hawkins PT; Stephens L. 2012. GPCR activation of Ras and PI3Kgamma in neutrophils depends on PLCbeta2/beta3 and the RasGEF RasGRP4. EMBO J :. [PubMed: 22728827]  [MGI Ref ID J:186412]

Sur C; Wafford KA; Reynolds DS; Hadingham KL; Bromidge F; Macaulay A; Collinson N; O'Meara G; Howell O; Newman R; Myers J; Atack JR; Dawson GR; McKernan RM; Whiting PJ; Rosahl TW. 2001. Loss of the major GABA(A) receptor subtype in the brain is not lethal in mice. J Neurosci 21(10):3409-18. [PubMed: 11331371]  [MGI Ref ID J:69290]

Tan CL; Plotkin JL; Veno MT; von Schimmelmann M; Feinberg P; Mann S; Handler A; Kjems J; Surmeier DJ; O'Carroll D; Greengard P; Schaefer A. 2013. MicroRNA-128 governs neuronal excitability and motor behavior in mice. Science 342(6163):1254-8. [PubMed: 24311694]  [MGI Ref ID J:205260]

Tan HO; Reid CA; Single FN; Davies PJ; Chiu C; Murphy S; Clarke AL; Dibbens L; Krestel H; Mulley JC; Jones MV; Seeburg PH; Sakmann B; Berkovic SF; Sprengel R; Petrou S. 2007. Reduced cortical inhibition in a mouse model of familial childhood absence epilepsy. Proc Natl Acad Sci U S A 104(44):17536-41. [PubMed: 17947380]  [MGI Ref ID J:127120]

Tanaka S; Kunii M; Harada A; Okabe S. 2009. Generation of cortactin floxed mice and cellular analysis of motility in fibroblasts. Genesis 47(9):638-46. [PubMed: 19621352]  [MGI Ref ID J:155986]

Tasan RO; Lin S; Hetzenauer A; Singewald N; Herzog H; Sperk G. 2009. Increased novelty-induced motor activity and reduced depression-like behavior in neuropeptide Y (NPY)-Y4 receptor knockout mice. Neuroscience 158(4):1717-30. [PubMed: 19121371]  [MGI Ref ID J:148974]

Tchorz JS; Suply T; Ksiazek I; Giachino C; Cloetta D; Danzer CP; Doll T; Isken A; Lemaistre M; Taylor V; Bettler B; Kinzel B; Mueller M. 2012. A modified RMCE-compatible Rosa26 locus for the expression of transgenes from exogenous promoters. PLoS One 7(1):e30011. [PubMed: 22253858]  [MGI Ref ID J:184312]

Temmerman L; Slonimsky E; Rosenthal N. 2010. Class 2 IGF-1 isoforms are dispensable for viability, growth and maintenance of IGF-1 serum levels. Growth Horm IGF Res :. [PubMed: 20382057]  [MGI Ref ID J:159167]

Teoh SS; Vieusseux J; Prakash M; Berkowicz S; Luu J; Bird CH; Law RH; Rosado C; Price JT; Whisstock JC; Bird PI. 2014. Maspin is not required for embryonic development or tumour suppression. Nat Commun 5:3164. [PubMed: 24445777]  [MGI Ref ID J:206439]

Teves ME; Zhang Z; Costanzo RM; Henderson SC; Corwin FD; Zweit J; Sundaresan G; Subler M; Salloum FN; Rubin BK; Strauss JF 3rd. 2013. Sperm-associated antigen-17 gene is essential for motile cilia function and neonatal survival. Am J Respir Cell Mol Biol 48(6):765-72. [PubMed: 23418344]  [MGI Ref ID J:211752]

Theis M; de Wit C; Schlaeger TM; Eckardt D; Kruger O; Doring B; Risau W; Deutsch U; Pohl U; Willecke K. 2001. Endothelium-specific replacement of the connexin43 coding region by a lacZ reporter gene. Genesis 29(1):1-13. [PubMed: 11135457]  [MGI Ref ID J:78662]

Thien CB; Scaife RM; Papadimitriou JM; Murphy MA; Bowtell DD; Langdon WY. 2003. A mouse with a loss-of-function mutation in the c-Cbl TKB domain shows perturbed thymocyte signaling without enhancing the activity of the ZAP-70 tyrosine kinase. J Exp Med 197(4):503-13. [PubMed: 12591907]  [MGI Ref ID J:81965]

Thomas T; Dixon MP; Kueh AJ; Voss AK. 2008. Mof (MYST1 or KAT8) is essential for progression of embryonic development past the blastocyst stage and required for normal chromatin architecture. Mol Cell Biol 28(16):5093-105. [PubMed: 18541669]  [MGI Ref ID J:139761]

Thorey IS; Muth K; Russ AP; Otte J; Reffelmann A; von Melchner H. 1998. Selective disruption of genes transiently induced in differentiating mouse embryonic stem cells by using gene trap mutagenesis and site-specific recombination. Mol Cell Biol 18(5):3081-8. [PubMed: 9566926]  [MGI Ref ID J:47007]

Tomasello E; Desmoulins PO; Chemin K; Guia S; Cremer H; Ortaldo J; Love P; Kaiserlian D; Vivier E. 2000. Combined natural killer cell and dendritic cell functional deficiency in KARAP/DAP12 loss-of-function mutant mice. Immunity 13(3):355-64. [PubMed: 11021533]  [MGI Ref ID J:64764]

Toy G; Austin WR; Liao HI; Cheng D; Singh A; Campbell DO; Ishikawa TO; Lehmann LW; Satyamurthy N; Phelps ME; Herschman HR; Czernin J; Witte ON; Radu CG. 2010. Requirement for deoxycytidine kinase in T and B lymphocyte development. Proc Natl Acad Sci U S A 107(12):5551-6. [PubMed: 20080663]  [MGI Ref ID J:158373]

Treiner E; Duban L; Bahram S; Radosavljevic M; Wanner V; Tilloy F; Affaticati P; Gilfillan S; Lantz O. 2003. Selection of evolutionarily conserved mucosal-associated invariant T cells by MR1. Nature 422(6928):164-9. [PubMed: 12634786]  [MGI Ref ID J:113083]

Trompouki E; Tsagaratou A; Kosmidis SK; Dolle P; Qian J; Kontoyiannis DL; Cardoso WV; Mosialos G. 2009. Truncation of the catalytic domain of the cylindromatosis tumor suppressor impairs lung maturation. Neoplasia 11(5):469-76. [PubMed: 19412431]  [MGI Ref ID J:162840]

Tuoc TC; Boretius S; Sansom SN; Pitulescu ME; Frahm J; Livesey FJ; Stoykova A. 2013. Chromatin Regulation by BAF170 Controls Cerebral Cortical Size and Thickness. Dev Cell 25(3):256-69. [PubMed: 23643363]  [MGI Ref ID J:197141]

Turpin SM; Nicholls HT; Willmes DM; Mourier A; Brodesser S; Wunderlich CM; Mauer J; Xu E; Hammerschmidt P; Bronneke HS; Trifunovic A; LoSasso G; Wunderlich FT; Kornfeld JW; Bluher M; Kronke M; Bruning JC. 2014. Obesity-induced CerS6-dependent C16:0 ceramide production promotes weight gain and glucose intolerance. Cell Metab 20(4):678-86. [PubMed: 25295788]  [MGI Ref ID J:215519]

Tuzi NL; Clarke AR; Bradford B; Aitchison L; Thomson V; Manson JC. 2004. Cre-loxP mediated control of PrP to study transmissible spongiform encephalopathy diseases. Genesis 40(1):1-6. [PubMed: 15354287]  [MGI Ref ID J:92302]

Tvrdik P; Capecchi MR. 2006. Reversal of Hox1 gene subfunctionalization in the mouse. Dev Cell 11(2):239-50. [PubMed: 16890163]  [MGI Ref ID J:119279]

Tzima S; Victoratos P; Kranidioti K; Alexiou M; Kollias G. 2009. Myeloid heme oxygenase-1 regulates innate immunity and autoimmunity by modulating IFN-beta production. J Exp Med 206(5):1167-79. [PubMed: 19398754]  [MGI Ref ID J:148498]

Ueki I; Roman HB; Valli A; Fieselmann K; Lam J; Peters R; Hirschberger LL; Stipanuk MH. 2011. Knockout of the murine cysteine dioxygenase gene results in severe impairment in ability to synthesize taurine and an increased catabolism of cysteine to hydrogen sulfide. Am J Physiol Endocrinol Metab 301(4):E668-84. [PubMed: 21693692]  [MGI Ref ID J:182195]

Ueki Y; Lin CY; Senoo M; Ebihara T; Agata N; Onji M; Saheki Y; Kawai T; Mukherjee PM; Reichenberger E; Olsen BR. 2007. Increased myeloid cell responses to M-CSF and RANKL cause bone loss and inflammation in SH3BP2 'cherubism' mice. Cell 128(1):71-83. [PubMed: 17218256]  [MGI Ref ID J:117880]

Uemura T; Sato T; Aoki T; Yamamoto A; Okada T; Hirai R; Harada R; Mori K; Tagaya M; Harada A. 2009. p31 deficiency influences endoplasmic reticulum tubular morphology and cell survival. Mol Cell Biol 29(7):1869-81. [PubMed: 19188447]  [MGI Ref ID J:147771]

Urness LD; Paxton CN; Wang X; Schoenwolf GC; Mansour SL. 2010. FGF signaling regulates otic placode induction and refinement by controlling both ectodermal target genes and hindbrain Wnt8a. Dev Biol 340(2):595-604. [PubMed: 20171206]  [MGI Ref ID J:160254]

Varinou L; Ramsauer K; Karaghiosoff M; Kolbe T; Pfeffer K; Muller M; Decker T. 2003. Phosphorylation of the Stat1 transactivation domain is required for full-fledged IFN-gamma-dependent innate immunity. Immunity 19(6):793-802. [PubMed: 14670297]  [MGI Ref ID J:130622]

Vennekens R; Olausson J; Meissner M; Bloch W; Mathar I; Philipp SE; Schmitz F; Weissgerber P; Nilius B; Flockerzi V; Freichel M. 2007. Increased IgE-dependent mast cell activation and anaphylactic responses in mice lacking the calcium-activated nonselective cation channel TRPM4. Nat Immunol 8(3):312-320. [PubMed: 17293867]  [MGI Ref ID J:118679]

Verma S; Hoffmann FW; Kumar M; Huang Z; Roe K; Nguyen-Wu E; Hashimoto AS; Hoffmann PR. 2011. Selenoprotein K knockout mice exhibit deficient calcium flux in immune cells and impaired immune responses. J Immunol 186(4):2127-37. [PubMed: 21220695]  [MGI Ref ID J:169169]

Vielnascher RM; Hainzl E; Leitner NR; Rammerstorfer M; Popp D; Witalisz A; Rom R; Karaghiosoff M; Kolbe T; Muller S; Rulicke T; Lassnig C; Strobl B; Muller M. 2014. Conditional ablation of TYK2 in immunity to viral infection and tumor surveillance. Transgenic Res 23(3):519-29. [PubMed: 24696087]  [MGI Ref ID J:215350]

Vijayanand P; Seumois G; Simpson LJ; Abdul-Wajid S; Baumjohann D; Panduro M; Huang X; Interlandi J; Djuretic IM; Brown DR; Sharpe AH; Rao A; Ansel KM. 2012. Interleukin-4 Production by Follicular Helper T Cells Requires the Conserved Il4 Enhancer Hypersensitivity Site V. Immunity 36(2):175-187. [PubMed: 22326582]  [MGI Ref ID J:181313]

Volckaert T; Dill E; Campbell A; Tiozzo C; Majka S; Bellusci S; De Langhe SP. 2011. Parabronchial smooth muscle constitutes an airway epithelial stem cell niche in the mouse lung after injury. J Clin Invest 121(11):4409-19. [PubMed: 21985786]  [MGI Ref ID J:178444]

Volna P; Lebduska P; Draberova L; Simova S; Heneberg P; Boubelik M; Bugajev V; Malissen B; Wilson BS; Horejsi V; Malissen M; Draber P. 2004. Negative regulation of mast cell signaling and function by the adaptor LAB/NTAL. J Exp Med 200(8):1001-13. [PubMed: 15477348]  [MGI Ref ID J:93950]

Vooijs M; Ong CT; Hadland B; Huppert S; Liu Z; Korving J; van den Born M; Stappenbeck T; Wu Y; Clevers H; Kopan R. 2007. Mapping the consequence of Notch1 proteolysis in vivo with NIP-CRE. Development 134(3):535-44. [PubMed: 17215306]  [MGI Ref ID J:119910]

Waisman A; Kraus M; Seagal J; Ghosh S; Melamed D; Song J; Sasaki Y; Classen S; Lutz C; Brombacher F; Nitschke L; Rajewsky K. 2007. IgG1 B cell receptor signaling is inhibited by CD22 and promotes the development of B cells whose survival is less dependent on Ig alpha/beta. J Exp Med 204(4):747-58. [PubMed: 17420268]  [MGI Ref ID J:125719]

Wallner B; Leitner NR; Vielnascher RM; Kernbauer E; Kolbe T; Karaghiosoff M; Rulicke T; Decker T; Muller M. 2012. Generation of mice with a conditional Stat1 null allele. Transgenic Res 21(1):217-24. [PubMed: 21553074]  [MGI Ref ID J:183580]

Walters KA; Allan CM; Jimenez M; Lim PR; Davey RA; Zajac JD; Illingworth P; Handelsman DJ. 2007. Female mice haploinsufficient for an inactivated androgen receptor (AR) exhibit age-dependent defects that resemble the AR null phenotype of dysfunctional late follicle development, ovulation, and fertility. Endocrinology 148(8):3674-84. [PubMed: 17463055]  [MGI Ref ID J:129631]

Wang CC; Ng CP; Shi H; Liew HC; Guo K; Zeng Q; Hong W. 2010. A role for VAMP8/endobrevin in surface deployment of the water channel aquaporin 2. Mol Cell Biol 30(1):333-43. [PubMed: 19841070]  [MGI Ref ID J:156248]

Wang CC; Shi H; Guo K; Ng CP; Li J; Gan BQ; Chien Liew H; Leinonen J; Rajaniemi H; Zhou ZH; Zeng Q; Hong W. 2007. VAMP8/endobrevin as a general vesicular SNARE for regulated exocytosis of the exocrine system. Mol Biol Cell 18(3):1056-63. [PubMed: 17215514]  [MGI Ref ID J:123895]

Wang D; Hoing S; Patterson HC; Ahmad UM; Rathinam VA; Rajewsky K; Fitzgerald KA; Golenbock DT. 2013. Inflammation in mice ectopically expressing human Pyogenic Arthritis, Pyoderma Gangrenosum, and Acne (PAPA) Syndrome-associated PSTPIP1 A230T mutant proteins. J Biol Chem 288(7):4594-601. [PubMed: 23293022]  [MGI Ref ID J:196002]

Wang M; Jin H; Tang D; Huang S; Zuscik MJ; Chen D. 2011. Smad1 plays an essential role in bone development and postnatal bone formation. Osteoarthritis Cartilage 19(6):751-62. [PubMed: 21420501]  [MGI Ref ID J:172689]

Wang N; Calpe S; Westcott J; Castro W; Ma C; Engel P; Schatzle JD; Terhorst C. 2010. Cutting edge: The adapters EAT-2A and -2B are positive regulators of CD244- and CD84-dependent NK cell functions in the C57BL/6 mouse. J Immunol 185(10):5683-7. [PubMed: 20962259]  [MGI Ref ID J:166054]

Wang P; Bowl MR; Bender S; Peng J; Farber L; Chen J; Ali A; Zhang Z; Alberts AS; Thakker RV; Shilatifard A; Williams BO; Teh BT. 2008. Parafibromin, a component of the human PAF complex, regulates growth factors and is required for embryonic development and survival in adult mice. Mol Cell Biol 28(9):2930-40. [PubMed: 18212049]  [MGI Ref ID J:135255]

Wang Y; Szretter KJ; Vermi W; Gilfillan S; Rossini C; Cella M; Barrow AD; Diamond MS; Colonna M. 2012. IL-34 is a tissue-restricted ligand of CSF1R required for the development of Langerhans cells and microglia. Nat Immunol 13(8):753-60. [PubMed: 22729249]  [MGI Ref ID J:187643]

Wartosch L; Fuhrmann JC; Schweizer M; Stauber T; Jentsch TJ. 2009. Lysosomal degradation of endocytosed proteins depends on the chloride transport protein ClC-7. FASEB J 23(12):4056-68. [PubMed: 19661288]  [MGI Ref ID J:155176]

Webster KE; O'Bryan MK; Fletcher S; Crewther PE; Aapola U; Craig J; Harrison DK; Aung H; Phutikanit N; Lyle R; Meachem SJ; Antonarakis SE; de Kretser DM; Hedger MP; Peterson P; Carroll BJ; Scott HS. 2005. Meiotic and epigenetic defects in Dnmt3L-knockout mouse spermatogenesis. Proc Natl Acad Sci U S A 102(11):4068-73. [PubMed: 15753313]  [MGI Ref ID J:97190]

Wei Y; Li L; Zhou X; Zhang QY; Dunbar A; Liu F; Kluetzman K; Yang W; Ding X. 2013. Generation and Characterization of a Novel Cyp2a(4/5)bgs-Null Mouse Model. Drug Metab Dispos 41(1):132-40. [PubMed: 23073733]  [MGI Ref ID J:190445]

Weissgerber P; Kriebs U; Tsvilovskyy V; Olausson J; Kretz O; Stoerger C; Vennekens R; Wissenbach U; Middendorff R; Flockerzi V; Freichel M. 2011. Male fertility depends on Ca(2)+ absorption by TRPV6 in epididymal epithelia. Sci Signal 4(171):ra27. [PubMed: 21540454]  [MGI Ref ID J:185996]

Welch JS; Yuan W; Ley TJ. 2011. PML-RARA can increase hematopoietic self-renewal without causing a myeloproliferative disease in mice. J Clin Invest 121(4):1636-45. [PubMed: 21364283]  [MGI Ref ID J:172024]

Wen L; Shinton SA; Hardy RR; Hayakawa K. 2005. Association of B-1 B cells with follicular dendritic cells in spleen. J Immunol 174(11):6918-26. [PubMed: 15905534]  [MGI Ref ID J:109979]

Wethmar K; Begay V; Smink JJ; Zaragoza K; Wiesenthal V; Dorken B; Calkhoven CF; Leutz A. 2010. C/EBPbetaDeltauORF mice--a genetic model for uORF-mediated translational control in mammals. Genes Dev 24(1):15-20. [PubMed: 20047998]  [MGI Ref ID J:155795]

Wetzel-Strong SE; Li M; Klein KR; Nishikimi T; Caron KM. 2014. Epicardial-derived adrenomedullin drives cardiac hyperplasia during embryogenesis. Dev Dyn 243(2):243-56. [PubMed: 24123312]  [MGI Ref ID J:206227]

White TA; Johnson T; Zarzhevsky N; Tom C; Delacroix S; Holroyd EW; Maroney SA; Singh R; Pan S; Fay WP; van Deursen J; Mast AE; Sandhu GS; Simari RD. 2010. Endothelial-derived tissue factor pathway inhibitor regulates arterial thrombosis but is not required for development or hemostasis. Blood 116(10):1787-94. [PubMed: 20516367]  [MGI Ref ID J:164530]

Wilanowski T; Caddy J; Ting SB; Hislop NR; Cerruti L; Auden A; Zhao LL; Asquith S; Ellis S; Sinclair R; Cunningham JM; Jane SM. 2008. Perturbed desmosomal cadherin expression in grainy head-like 1-null mice. EMBO J 27(6):886-97. [PubMed: 18288204]  [MGI Ref ID J:133318]

Wildner H; Muller T; Cho SH; Brohl D; Cepko CL; Guillemot F; Birchmeier C. 2006. dILA neurons in the dorsal spinal cord are the product of terminal and non-terminal asymmetric progenitor cell divisions, and require Mash1 for their development. Development 133(11):2105-13. [PubMed: 16690754]  [MGI Ref ID J:109482]

Will C; Breiderhoff T; Thumfart J; Stuiver M; Kopplin K; Sommer K; Gunzel D; Querfeld U; Meij IC; Shan Q; Bleich M; Willnow TE; Muller D. 2010. Targeted deletion of murine Cldn16 identifies extra- and intrarenal compensatory mechanisms of Ca2+ and Mg2+ wasting. Am J Physiol Renal Physiol :. [PubMed: 20147368]  [MGI Ref ID J:159706]

Willenborg S; Lucas T; van Loo G; Knipper JA; Krieg T; Haase I; Brachvogel B; Hammerschmidt M; Nagy A; Ferrara N; Pasparakis M; Eming SA. 2012. CCR2 recruits an inflammatory macrophage subpopulation critical for angiogenesis in tissue repair. Blood 120(3):613-25. [PubMed: 22577176]  [MGI Ref ID J:189044]

Wilson-Perez HE; Chambers AP; Ryan KK; Li B; Sandoval DA; Stoffers D; Drucker DJ; Perez-Tilve D; Seeley RJ. 2013. Vertical sleeve gastrectomy is effective in two genetic mouse models of glucagon-like Peptide 1 receptor deficiency. Diabetes 62(7):2380-5. [PubMed: 23434938]  [MGI Ref ID J:206563]

Wortge S; Eshkind L; Cabezas-Wallscheid N; Lakaye B; Kim J; Heck R; Abassi Y; Diken M; Sprengel R; Bockamp E. 2010. Tetracycline-controlled transgene activation using the ROSA26-iM2-GFP knock-in mouse strain permits GFP monitoring of DOX-regulated transgene-expression. BMC Dev Biol 10:95. [PubMed: 20815887]  [MGI Ref ID J:165820]

Wright MD; Geary SM; Fitter S; Moseley GW; Lau LM; Sheng KC; Apostolopoulos V; Stanley EG; Jackson DE; Ashman LK. 2004. Characterization of mice lacking the tetraspanin superfamily member CD151. Mol Cell Biol 24(13):5978-88. [PubMed: 15199151]  [MGI Ref ID J:91605]

Wylie AA; Pulford DJ; McVie-Wylie AJ; Waterland RA; Evans HK; Chen YT; Nolan CM; Orton TC; Jirtle RL. 2003. Tissue-specific inactivation of murine M6P/IGF2R. Am J Pathol 162(1):321-8. [PubMed: 12507915]  [MGI Ref ID J:80932]

Xiao C; Calado DP; Galler G; Thai TH; Patterson HC; Wang J; Rajewsky N; Bender TP; Rajewsky K. 2007. MiR-150 controls B cell differentiation by targeting the transcription factor c-Myb. Cell 131(1):146-59. [PubMed: 17923094]  [MGI Ref ID J:127234]

Xiao J; Dai R; Negyessy L; Bergson C. 2006. Calcyon, a novel partner of clathrin light chain, stimulates clathrin-mediated endocytosis. J Biol Chem 281(22):15182-93. [PubMed: 16595675]  [MGI Ref ID J:146583]

Xie R; Jiang R; Chen D. 2011. Generation of Axin1 conditional mutant mice. Genesis 49(2):98-102. [PubMed: 21344612]  [MGI Ref ID J:169694]

Xu W; Liu C; Kaartinen V; Chen H; Lu CH; Zhang W; Luo Y; Shi W. 2013. TACE in perinatal mouse lung epithelial cells promotes lung saccular formation. Am J Physiol Lung Cell Mol Physiol 305(12):L953-63. [PubMed: 24142516]  [MGI Ref ID J:210193]

Yang XO; Angkasekwinai P; Zhu J; Peng J; Liu Z; Nurieva R; Liu X; Chung Y; Chang SH; Sun B; Dong C. 2009. Requirement for the basic helix-loop-helix transcription factor Dec2 in initial TH2 lineage commitment. Nat Immunol 10(12):1260-6. [PubMed: 19881507]  [MGI Ref ID J:157740]

Yang Z; Sullivan BM; Allen CD. 2012. Fluorescent in vivo detection reveals that IgE(+) B cells are restrained by an intrinsic cell fate predisposition. Immunity 36(5):857-72. [PubMed: 22406270]  [MGI Ref ID J:187336]

Ye M; Ermakova O; Graf T. 2005. PU.1 is not strictly required for B cell development and its absence induces a B-2 to B-1 cell switch. J Exp Med 202(10):1411-22. [PubMed: 16301746]  [MGI Ref ID J:118844]

Yin Z; Menendez D; Resnick MA; French JE; Janardhan KS; Jetten AM. 2012. RAP80 is critical in maintaining genomic stability and suppressing tumor development. Cancer Res 72(19):5080-90. [PubMed: 22896338]  [MGI Ref ID J:191827]

Yokoi F; Dang MT; Mitsui S; Li J; Li Y. 2008. Motor Deficits and Hyperactivity in Cerebral Cortex-specific Dyt1 Conditional Knockout Mice. J Biochem 143(1):39-47. [PubMed: 17956903]  [MGI Ref ID J:130483]

Yokoi F; Dang MT; Mitsui S; Li Y. 2005. Exclusive paternal expression and novel alternatively spliced variants of epsilon-sarcoglycan mRNA in mouse brain. FEBS Lett 579(21):4822-8. [PubMed: 16099459]  [MGI Ref ID J:101332]

York IA; Brehm MA; Zendzian S; Towne CF; Rock KL. 2006. Endoplasmic reticulum aminopeptidase 1 (ERAP1) trims MHC class I-presented peptides in vivo and plays an important role in immunodominance. Proc Natl Acad Sci U S A 103(24):9202-7. [PubMed: 16754858]  [MGI Ref ID J:111047]

Yu J; Sadhukhan S; Noriega LG; Moullan N; He B; Weiss RS; Lin H; Schoonjans K; Auwerx J. 2013. Metabolic characterization of a Sirt5 deficient mouse model. Sci Rep 3:2806. [PubMed: 24076663]  [MGI Ref ID J:205149]

Yu S; Crawford D; Tsuchihashi T; Behrens TW; Srivastava D. 2011. The chemokine receptor CXCR7 functions to regulate cardiac valve remodeling. Dev Dyn 240(2):384-93. [PubMed: 21246655]  [MGI Ref ID J:167833]

Yu Z; Lin KK; Bhandari A; Spencer JA; Xu X; Wang N; Lu Z; Gill GN; Roop DR; Wertz P; Andersen B. 2006. The Grainyhead-like epithelial transactivator Get-1/Grhl3 regulates epidermal terminal differentiation and interacts functionally with LMO4. Dev Biol 299(1):122-36. [PubMed: 16949565]  [MGI Ref ID J:114626]

Zhang H; Li S; Doan T; Rieke F; Detwiler PB; Frederick JM; Baehr W. 2007. Deletion of PrBP/delta impedes transport of GRK1 and PDE6 catalytic subunits to photoreceptor outer segments. Proc Natl Acad Sci U S A 104(21):8857-62. [PubMed: 17496142]  [MGI Ref ID J:121745]

Zhang Y; Conti MA; Malide D; Dong F; Wang A; Shmist YA; Liu C; Zerfas P; Daniels MP; Chan CC; Kozin E; Kachar B; Kelley MJ; Kopp JB; Adelstein RS. 2012. Mouse models of MYH9-related disease: mutations in nonmuscle myosin II-A Blood 119(1):238-5. [PubMed: 21908426]  [MGI Ref ID J:175367]

Zhang Z; Hofmann C; Casanova E; Schutz G; Lutz B. 2004. Generation of a conditional allele of the CBP gene in mouse. Genesis 40(2):82. [PubMed: 15452871]  [MGI Ref ID J:93192]

Zhao C; Guo H; Li J; Myint T; Pittman W; Yang L; Zhong W; Schwartz RJ; Schwarz JJ; Singer HA; Tallquist MD; Wu M. 2014. Numb family proteins are essential for cardiac morphogenesis and progenitor differentiation. Development 141(2):281-95. [PubMed: 24335256]  [MGI Ref ID J:206589]

Zhao H; Kim G; Levine RL. 2012. Methionine sulfoxide reductase contributes to meeting dietary methionine requirements. Arch Biochem Biophys 522(1):37-43. [PubMed: 22521563]  [MGI Ref ID J:196824]

Zhao H; Reed RR. 2001. X inactivation of the OCNC1 channel gene reveals a role for activity-dependent competition in the olfactory system. Cell 104(5):651-60. [PubMed: 11257220]  [MGI Ref ID J:77304]

Zhou CJ; Wang YZ; Yamagami T; Zhao T; Song L; Wang K. 2009. Generation of Lrp6 conditional gene-targeting mouse line for modeling and dissecting multiple birth defects/congenital anomalies. Dev Dyn 239(1):318-326. [PubMed: 19653321]  [MGI Ref ID J:155250]

Zhu JW; Brdicka T; Katsumoto TR; Lin J; Weiss A. 2008. Structurally distinct phosphatases CD45 and CD148 both regulate B cell and macrophage immunoreceptor signaling. Immunity 28(2):183-96. [PubMed: 18249142]  [MGI Ref ID J:131736]

Zigrino P; Kuhn I; Bauerle T; Zamek J; Fox JW; Neumann S; Licht A; Schorpp-Kistner M; Angel P; Mauch C. 2009. Stromal expression of MMP-13 is required for melanoma invasion and metastasis. J Invest Dermatol 129(11):2686-93. [PubMed: 19516266]  [MGI Ref ID J:157135]

Zouvelou V; Passa O; Segklia K; Tsalavos S; Valenzuela DM; Economides AN; Graf D. 2009. Generation and functional characterization of mice with a conditional BMP7 allele. Int J Dev Biol 53(4):597-603. [PubMed: 19247966]  [MGI Ref ID J:149134]

Health & husbandry

Health & Colony Maintenance Information

Animal Health Reports

Room Number           AX11

Colony Maintenance

Breeding & HusbandryWhen maintaining a live colony, these mice are bred as homozygotes. The cre transgene appears to be X-linked since transgene transmission through males is restricted to female offspring.
Mating SystemHomozygote x Hemizygote         (Female x Male)   25-APR-08
Diet Information LabDiet® 5K52/5K67

Pricing and Purchasing

Pricing, Supply Level & Notes, Controls

Pricing for USA, Canada and Mexico shipping destinations View International Pricing

Live Mice

Price per mouse (US dollars $)GenderGenotypes Provided
Individual Mouse $232.00MaleHemizygous for Tg(CMV-cre)1Cgn  
$232.00FemaleHomozygous for Tg(CMV-cre)1Cgn  
Price per Pair (US dollars $)Pair Genotype
$464.00Homozygous for Tg(CMV-cre)1Cgn x Hemizygous for Tg(CMV-cre)1Cgn  

Standard Supply

Repository-Live represents an exclusive set of over 1800 unique mouse models across a vast array of research areas. Breeding colonies provide mice for large and small orders and fluctuate in size depending on current research demand. If a strain is not immediately available, you will receive an estimated availability timeframe for your inquiry or order in 2-3 business days. Repository strains typically are delivered at 4 to 8 weeks of age. Requests for specific ages will be noted but not guaranteed and we do not accept age requests for breeder pairs. However, if cohorts of mice (5 or more of one gender) are needed at a specific age range for experiments, we will do our best to accommodate your age request.

Pricing for International shipping destinations View USA Canada and Mexico Pricing

Live Mice

Price per mouse (US dollars $)GenderGenotypes Provided
Individual Mouse $301.60MaleHemizygous for Tg(CMV-cre)1Cgn  
$301.60FemaleHomozygous for Tg(CMV-cre)1Cgn  
Price per Pair (US dollars $)Pair Genotype
$603.20Homozygous for Tg(CMV-cre)1Cgn x Hemizygous for Tg(CMV-cre)1Cgn  

Standard Supply

Repository-Live represents an exclusive set of over 1800 unique mouse models across a vast array of research areas. Breeding colonies provide mice for large and small orders and fluctuate in size depending on current research demand. If a strain is not immediately available, you will receive an estimated availability timeframe for your inquiry or order in 2-3 business days. Repository strains typically are delivered at 4 to 8 weeks of age. Requests for specific ages will be noted but not guaranteed and we do not accept age requests for breeder pairs. However, if cohorts of mice (5 or more of one gender) are needed at a specific age range for experiments, we will do our best to accommodate your age request.

View USA Canada and Mexico Pricing View International Pricing

Standard Supply

Repository-Live represents an exclusive set of over 1800 unique mouse models across a vast array of research areas. Breeding colonies provide mice for large and small orders and fluctuate in size depending on current research demand. If a strain is not immediately available, you will receive an estimated availability timeframe for your inquiry or order in 2-3 business days. Repository strains typically are delivered at 4 to 8 weeks of age. Requests for specific ages will be noted but not guaranteed and we do not accept age requests for breeder pairs. However, if cohorts of mice (5 or more of one gender) are needed at a specific age range for experiments, we will do our best to accommodate your age request.

Control Information

   000664 C57BL/6J
  Considerations for Choosing Controls
  Control Pricing Information for Genetically Engineered Mutant Strains.

Payment Terms and Conditions

Terms are granted by individual review and stated on the customer invoice(s) and account statement. These transactions are payable in U.S. currency within the granted terms. Payment for services, products, shipping containers, and shipping costs that are rendered are expected within the payment terms indicated on the invoice or stated by contract. Invoices and account balances in arrears of stated terms may result in The Jackson Laboratory pursuing collection activities including but not limited to outside agencies and court filings.

See Terms of Use tab for General Terms and Conditions

The Jackson Laboratory's Genotype Promise

The Jackson Laboratory has rigorous genetic quality control and mutant gene genotyping programs to ensure the genetic background of JAX® Mice strains as well as the genotypes of strains with identified molecular mutations. JAX® Mice strains are only made available to researchers after meeting our standards. However, the phenotype of each strain may not be fully characterized and/or captured in the strain data sheets. Therefore, we cannot guarantee a strain's phenotype will meet all expectations. To ensure that JAX® Mice will meet the needs of individual research projects or when requesting a strain that is new to your research, we suggest ordering and performing tests on a small number of mice to determine suitability for your particular project.
Ordering Information
JAX® Mice
Surgical and Preconditioning Services
JAX® Services
Customer Services and Support
Tel: 1-800-422-6423 or 1-207-288-5845
Fax: 1-207-288-6150
Technical Support Email Form

Terms of Use

Terms of Use

General Terms and Conditions

For Licensing and Use Restrictions view the link(s) below:
- Use of MICE by companies or for-profit entities requires a license prior to shipping.

Contact information

General inquiries regarding Terms of Use

Contracts Administration


JAX® Mice, Products & Services Conditions of Use

"MICE" means mouse strains, their progeny derived by inbreeding or crossbreeding, unmodified derivatives from mouse strains or their progeny supplied by The Jackson Laboratory ("JACKSON"). "PRODUCTS" means biological materials supplied by JACKSON, and their derivatives. "RECIPIENT" means each recipient of MICE, PRODUCTS, or services provided by JACKSON including each institution, its employees and other researchers under its control. MICE or PRODUCTS shall not be: (i) used for any purpose other than the internal research, (ii) sold or otherwise provided to any third party for any use, or (iii) provided to any agent or other third party to provide breeding or other services. Acceptance of MICE or PRODUCTS from JACKSON shall be deemed as agreement by RECIPIENT to these conditions, and departure from these conditions requires JACKSON's prior written authorization.

No Warranty


In case of dissatisfaction for a valid reason and claimed in writing by a purchaser within ninety (90) days of receipt of mice, products or services, JACKSON will, at its option, provide credit or replacement for the mice or product received or the services provided.

No Liability

In no event shall JACKSON, its trustees, directors, officers, employees, and affiliates be liable for any causes of action or damages, including any direct, indirect, special, or consequential damages, arising out of the provision of MICE, PRODUCTS or services, including economic damage or injury to property and lost profits, and including any damage arising from acts or negligence on the part of JACKSON, its agents or employees. Unless prohibited by law, in purchasing or receiving MICE, PRODUCTS or services from JACKSON, purchaser or recipient, or any party claiming by or through them, expressly releases and discharges JACKSON from all such causes of action or damages, and further agrees to defend and indemnify JACKSON from any costs or damages arising out of any third party claims.

MICE and PRODUCTS are to be used in a safe manner and in accordance with all applicable governmental rules and regulations.

The foregoing represents the General Terms and Conditions applicable to JACKSON’s MICE, PRODUCTS or services. In addition, special terms and conditions of sale of certain MICE, PRODUCTS or services may be set forth separately in JACKSON web pages, catalogs, price lists, contracts, and/or other documents, and these special terms and conditions shall also govern the sale of these MICE, PRODUCTS and services by JACKSON, and by its licensees and distributors.

Acceptance of delivery of MICE, PRODUCTS or services shall be deemed agreement to these terms and conditions. No purchase order or other document transmitted by purchaser or recipient that may modify the terms and conditions hereof, shall be in any way binding on JACKSON, and instead the terms and conditions set forth herein, including any special terms and conditions set forth separately, shall govern the sale of MICE, PRODUCTS or services by JACKSON.