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Strain Name: |
B6.Cg-Tg(CAG-Bgeo,-DsRed*MST)1Nagy/J |
Stock Number: |
006055 |
Availability:
| Repository- Live |
| Former Name |
B6.Cg-Tg(ACTB-Bgeo,-DsRed*MST)1Nagy/J (Changed: 08-MAY-08
)
|
| Genes & Alleles |
ACTB;
Bgeo;
DsRed;
Tg(CAG-Bgeo,-DsRed*MST)1Nagy;
|
Product Information
Strain Details
| Type |
JAX® GEMM® Strain -
Congenic |
| Additional information on
JAX® GEMM® Strains. |
| Type |
JAX® GEMM® Strain -
Mutant Strain |
| Type |
JAX® GEMM® Strain -
Transgenic |
| Mating System | Inbred x Hemizygote
(Female x Male) |
|---|
| |
| Species | laboratory mouse |
| Donating Investigator | IMR Colony, The Jackson Laboratory |
| Generation | ?+N7
(19-DEC-07)
|
|
|
Strain Description
While mice hemizygous for the transgenic insert (on an outbred genetic background, see Stock No. 005438) are reported to be viable and fertile, it has been our experience at The Jackson Laboratory that hemizygous animals are often smaller than littermates and subject to postnatal mortality. Delayed weaning greatly enhances the survival. Although homozygous animals are born, animals have not survived past 5 weeks of age. These transgenic mice express beta-galactosidase (lacZ) under the control of the chicken beta actin promoter coupled with the cytomegalovirus (CMV) immediate early enhancer. When crossed with a Cre recombinase-expressing strain, lacZ expression is replaced with red fluorescent protein expression in tissues expressing Cre recombinase. This double reporter system makes it possible to distinguish a lack of reporter expression from a lack of Cre recombinase expression while providing a means to assess Cre excision activity in live animals and cells.
In an attempt to offer alleles on well-characterized or multiple genetic backgrounds, alleles are frequently moved to a genetic background different from that on which an allele was first characterized. It should be noted that the phenotype could vary from that originally described. We will modify the strain description if necessary as published results become available.
Strain Development
A transgenic construct containing a Red Fluorescent Protein variant (DsRed.MST) gene under the control of the a chicken beta actin promoter coupled with the cytomegalovirus (CMV) immediate early enhancer upstream of a loxP site flanked beta-geo gene, was introduced into 129S6B6F1 derived G4 embryonic stem (ES) cells. ES cell clone containing one copy of the transgene and expressing LacZ was aggregated with ICR outbred tetraploid embryos to generate chimeric mice. The resulting chimeric male animal was bred with an ICR outbred female. Progeny from this cross, that were hemizygous for the transgene, were bred to ICR outbred mice. Upon arrival at The Jackson Laboratory (as Stock No. 005438), some mutant mice were backcrossed to C57BL/6J for at least 5 generations to establish this congenic strain (Stock No. 006055).
Gene & Allele Details
| Allele Symbol |
Tg(CAG-Bgeo,-DsRed*MST)1Nagy |
| Allele Name |
transgene insertion 1, Andras Nagy |
| Common Name(s) |
11/C1;
Tg(ACTB-Bgeo,-DsRed*MST)1Nagy;
Z/RED;
|
| Mutation Made By | Kristina Vintersten, Mount Sinai Hospital, SLRI |
| Strain of Origin | (129S6/SvEvTac x C57BL/6)F1 |
| ES Cell Line Name | Other (see notes) |
| Site of Expression | lacZ is expressed in embryonic and adult tissues; when crossed with a cre recombinase-expressing strain, lacZ expression is replaced with Red Fluorescent Protein variant (DsRed.MST) expression |
| Expressed Gene |
DsRed, red fluorescent protein, |
| Expressed Gene |
Bgeo, fusion of beta-galactosidase and neomycin phosphotransferase genes
, E. coli |
| Promoter |
ACTB, actin, beta, human |
| General Note |
The transgenic ES cell clone 11/C1, created by electroporation of (129S6/SvEvTac x C57BL/6)F1-derived G4 ES cells, was used to generate transgenic mice. The authors originally identified the red fluorescent protein variant employed in constructing the transgene vector as DsRed.T3; in a later erratum, they corrected this to DsRed-MST, which differs from the former at two amino acid positions (K Vintersten et al. 2005. Genesis 42(3):218). |
| Molecular Note |
The transgene contains the coding sequence for the DsRed*MST variant red fluorescent protein and a polyadenylation signal downstream of a loxP-flanked lacZ/neomycin resistance fusion gene (Betageo) followed by three polyadenylation signals (STOP sequence); both coding sequences reside downstream of a chicken beta-actin promoter and a cytomegalovirus enhancer. Excision of the lacZ-STOP by Cre recombinase in doubly transgenic ES cells or mice leads to expression of DsRed*MST; use of a ubiquitously expressed cre transgene results in fluorescence of ES cells, embryos and adult mice. [MGI Ref ID J:109837]
|
Control Information
Genotyping Protocols
ACTB-DsRed.MST
Bgeo
Colony Maintenance
| Breeding & Husbandry | It has been our experience at The Jackson Laboratory that hemizygotes maintained on a mixed genetic background (see Stock No. 005438) are often smaller than littermates and subject to postnatal mortality. Delayed weaning greatly enhances the survival. Additionally, smaller mice or mice with improper tooth development may benefit from adding pulverized (and/or increased fat) chow to the cage floor prior to and after weaning to promote the survival of the transgenic pups. Although homozygous animals are born, animals have not survived past 5 weeks of age. Given this, as well as the possibility that fluorescent protein polymer formation may result in DsRed-expressing mice, hemizygous mice are bred to wildtype siblings or to C57BL/6J mice. |
| Diet Information |
LabDiet® 5K20
|
Related Strains
Fluorescent Protein Strains
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| 004218 | B6.129(ICR)-Tg(CAG-ECFP)CK6Nagy/J |
| 006071 | B6.129-Gt(ROSA)26Sortm1Luo/J |
| 006080 | B6.129-Gt(ROSA)26Sortm2Luo/J |
| 006075 | B6.129-Gt(ROSA)26Sortm3Luo/J |
| 006412 | B6.129-Il12btm1Lky/J |
| 008451 | B6.129P(Cg)-Ptprca Cx3cr1tm1Litt/LittJ |
| 005582 | B6.129P-Cx3cr1tm1Litt/J |
| 007572 | B6.129P2(Cg)-Rorctm2Litt/J |
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| 007669 | B6.129S4-Pdgfratm11(EGFP)Sor/J |
| 006852 | B6.129S6-Per2tm1Jt/J |
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| 003479 | B6.C3-Tg(Fos-luc)1Rnd/J |
| 006772 | B6.Cg-Foxp3tm2Tch/J |
| 005670 | B6.Cg-Gt(ROSA)26Sortm1(rtTA,EGFP)Nagy/J |
| 005491 | B6.Cg-Mapttm1(EGFP)Klt Tg(MAPT)8cPdav/J |
| 005622 | B6.Cg-Shhtm1(EGFP/cre)Cjt/J |
| 007484 | B6.Cg-Tyrc-2J Tg(Tyr)3412ARpw Tg(Sry-EGFP)92Ei/EiJ |
| 004178 | B6.Cg-Tg(CAG-Bgeo/GFP)21Lbe/J |
| 006051 | B6.Cg-Tg(CAG-DsRed*MST)1Nagy/J |
| 005884 | B6.Cg-Tg(CAG-mRFP1)1F1Hadj/J |
| 006069 | B6.Cg-Tg(HIST1H2BB/EGFP)1Pa/J |
| 005029 | B6.Cg-Tg(Hlxb9-GFP)1Tmj/J |
| 006098 | B6.Cg-Tg(Il2/NFAT-luc)83Rinc/J |
| 006864 | B6.Cg-Tg(Ins1-EGFP)1Hara/J |
| 005244 | B6.Cg-Tg(Krt1-15-EGFP)2Cot/J |
| 007902 | B6.Cg-Tg(RP23-268L19-EGFP)2Mik/J |
| 007894 | B6.Cg-Tg(Rgs4-EGFP)4Lvt/J |
| 006361 | B6.Cg-Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/J |
| 004659 | B6.Cg-Tg(TIE2GFP)287Sato/1J |
| 006101 | B6.Cg-Tg(TRE/Prl-luc)31FlvRinc/J |
| 007901 | B6.Cg-Tg(Thy1-Brainbow1.0)HLich/J |
| 007911 | B6.Cg-Tg(Thy1-Brainbow1.1)MLich/J |
| 007921 | B6.Cg-Tg(Thy1-Brainbow2.1)RLich/J |
| 003710 | B6.Cg-Tg(Thy1-CFP)23Jrs/J |
| 007940 | B6.Cg-Tg(Thy1-CFP/COX8A)C1Lich/J |
| 007612 | B6.Cg-Tg(Thy1-COP4/EYFP)18Gfng/J |
| 007615 | B6.Cg-Tg(Thy1-COP4/EYFP)9Gfng/J |
| 005630 | B6.Cg-Tg(Thy1-EYFP)15Jrs/J |
| 003709 | B6.Cg-Tg(Thy1-YFP)16Jrs/J |
| 005627 | B6.Cg-Tg(Thy1-YFP/Syp)10Jrs/J |
| 003782 | B6.Cg-Tg(Thy1-YFPH)2Jrs/J |
| 007606 | B6.Cg-Tg(Thy1-cre/ESR1,-EYFP)AGfng/J |
| 006000 | B6.FVB-Tg(ITGAM-DTR/EGFP)34Lan/J |
| 004509 | B6.FVB-Tg(Itgax-DTR/EGFP)57Lan/J |
| 006417 | B6.FVB-Tg(Npy-hrGFP)1Lowl/J |
| 005738 | B6.FVB-Tg(tetO-EGFP,-Tgfbr2)8Mcle/J |
| 004077 | B6;129-Gt(ROSA)26Sortm2Sho/J |
| 008295 | B6;129-Syt9tm1Sud/J |
| 006676 | B6;129P2-Olfr151tm26Mom/MomJ |
| 006667 | B6;129P2-Omptm3Mom/MomJ |
| 004858 | B6;129S1-Tshrtm1Rmar/J |
| 007843 | B6;129S4-Efnb2tm2Sor/J |
| 008214 | B6;129S4-Pou5f1tm2Jae/J |
| 006614 | B6;CB-Tg(Thy1-CFP/COX8A)C1Lich/J |
| 006617 | B6;CB-Tg(Thy1-CFP/COX8A)S2Lich/J |
| 004966 | B6;CBA-Tg(Acrv1-EGFP)2727Redd/J |
| 004654 | B6;CBA-Tg(Pou5f1-EGFP)2Mnn/J |
| 007910 | B6;CBA-Tg(Thy1-Brainbow1.0)LLich/J |
| 005621 | B6;D2-Tg(S100B-EGFP)1Wjt/J |
| 005620 | B6;D2-Tg(S100B-EYFP)1Wjt/J |
| 004690 | B6;FVB-Tg(Pcp2-EGFP)2Yuza/J |
| 006147 | B6;FVB-Tg(Sfpi1,-EGFP)7Dgt/J |
| 006043 | B6;SJL-Tg(Oxt/EGFP)AI03Wsy/J |
| 008004 | B6;SJL-Tg(Thy1-ECFP/VAMP2)1Sud/J |
| 007610 | B6;SJL-Tg(Thy1-cre/ESR1,-EYFP)VGfng/J |
| 007880 | B6SJL-Tg(Thy1-Stx1a/EYFP)1Sud/J |
| 007856 | B6SJL-Tg(Thy1-Syt1/ECFP)1Sud/J |
| 004190 | C.129-Il4tm1Lky/J |
| 005700 | C.129P2-Cxcr6tm1Litt/J |
| 006769 | C.Cg-Foxp3tm2Tch/J |
| 004512 | C.FVB-Tg(Itgax-DTR/EGFP)57Lan/J |
| 008242 | C57BL/6-Gt(ROSA)26Sortm1(Ikbkb)Mass/J |
| 006567 | C57BL/6-Tg(CAG-EGFP)131Osb/LeySopJ |
| 003291 | C57BL/6-Tg(CAG-EGFP)1Osb/J |
| 005070 | C57BL/6-Tg(Csf1r-EGFP-NGFR/FKBP1A/TNFRSF6)2Bck/J |
| 004353 | C57BL/6-Tg(UBC-GFP)30Scha/J |
| 005706 | C57BL/6-Tg(tetO-CDK5R1/GFP)337Lht/J |
| 006618 | C57BL/6-Tg(tetO-COX8A/EYFP)1Ksn/J |
| 006362 | C57BL/6J-Tg(CMV-Cox8a/EYFP)17J/J |
| 003927 | C57BL/6J-Tg(Sry-EGFP)92Ei/EiJ |
| 007677 | CB6-Tg(Gad1-EGFP)G42Zjh/J |
| 007076 | CByJ.B6-Tg(UBC-GFP)30Scha/J |
| 003718 | FVB-Tg(GadGFP)45704Swn/J |
| 005515 | FVB-Tg(ITGAM-DTR/EGFP)34Lan/J |
| 006421 | FVB-Tg(Pomc1-hrGFP)1Lowl/J |
| 005125 | FVB.129S6(B6)-Gt(ROSA)26Sortm1(Luc)Kael/J |
| 006206 | FVB.129S6-Gt(ROSA)26Sortm1(HIF1A/luc)Kael/J |
| 003516 | FVB.Cg-Tg(CAG-EGFP)B5Nagy/J |
| 007483 | FVB.Cg-Tg(Tyr)3412ARpw Tg(Sry-EGFP)92Ei/EiJ |
| 003257 | FVB/N-Tg(GFAPGFP)14Mes/J |
| 006698 | NOD.Cg-Il4tm1Lky/JbsJ |
| 008173 | NOD.Cg-Tg(Ins1-EGFP)1Hara/QtngJ |
| 005076 | NOD.Cg-Tg(tetO-EGFP/FADD)1Doi/DoiJ |
| 005082 | NOD/ShiLt-Tg(ACTB-Ica1/EGFP)18Mdos/MdosJ |
| 005328 | NOD/ShiLt-Tg(Cd4-DsRed)4Lt/J |
| 005334 | NOD/ShiLt-Tg(Cd4-EGFP)1Lt/J |
| 005282 | NOD/ShiLtJ-Tg(Ins1-EGFP/GH1)14Hara/HaraJ |
| 006331 | STOCK Gt(ROSA)26Sortm1(DTA)Jpmb/J |
| 005130 | STOCK Gt(ROSA)26Sortm1(Smo/EYFP)Amc/J |
| 005572 | STOCK Gt(ROSA)26Sortm1(rtTA,EGFP)Nagy/J |
| 007576 | STOCK Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/J |
| 004808 | STOCK Mapttm1(EGFP)Klt Tg(MAPT)8cPdav/J |
| 004779 | STOCK Mapttm1(EGFP)Klt/J |
| 006741 | STOCK Olfr160tm1Mom Tg(Olfr151,taulacZ)BMom/MomJ |
| 006678 | STOCK Olfr160tm6Mom/MomJ |
| 006669 | STOCK Olfr17tm7Mom/MomJ |
| 006570 | STOCK Smn1tm1Msd Tg(Hlxb9-GFP)1Tmj Tg(SMN2)89Ahmb/J |
| 007879 | STOCK Stx1atm2Sud/J |
| 005438 | STOCK Tg(CAG-Bgeo,-DsRed*MST)1Nagy/J |
| 006850 | STOCK Tg(CAG-Bgeo,-NOTCH1,-EGFP)1Lbe/J |
| 006876 | STOCK Tg(CAG-Bgeo,-TEL/AML1,-EGFP)A6Lbe/J |
| 003920 | STOCK Tg(CAG-Bgeo/GFP)21Lbe/J |
| 005441 | STOCK Tg(CAG-DsRed*MST)1Nagy/J |
| 003773 | STOCK Tg(CAG-ECFP)CK6Nagy/J |
| 003115 | STOCK Tg(CAG-EGFP)B5Nagy/J |
| 003116 | STOCK Tg(CAG-EGFP)D4Nagy/J |
| 005645 | STOCK Tg(CAG-mRFP1)1F1Hadj/J |
| 005105 | STOCK Tg(Chx10-EGFP/cre-ALPP)2Clc/J |
| 005854 | STOCK Tg(Cp-EGFP)25Gaia/J |
| 006334 | STOCK Tg(Gad1-EGFP)94Agmo/J |
| 006340 | STOCK Tg(Gad1-EGFP)98Agmo/J |
| 007896 | STOCK Tg(Gt(ROSA)26Sor-EGFP)I1Able/J |
| 005418 | STOCK Tg(HIST1H2BB/EGFP)1Pa/J |
| 006866 | STOCK Tg(Ins1-DsRed*T4)32Hara/J |
| 006784 | STOCK Tg(Ins1-ECFP)24Hara/J |
| 003658 | STOCK Tg(TIE2GFP)287Sato/J |
| 006129 | STOCK Tg(Zp3-EGFP)1Dean/J |
| 003274 | STOCK Tg(tetNZL)2Bjd/J |
| 005104 | STOCK Tg(tetO-HIST1H2BJ/GFP)47Efu/J |
| 005699 | STOCK Tg(tetO-Ipf1,EGFP)956.6Macd/J |
View Fluorescent Protein Strains (139 strains)
lacZ Expression Strains
| 002484 | 129-Alpltm1Sor/J |
| 002292 | 129-Gt(ROSA)26Sor/J |
| 006050 | 129-Sirt6tm1Fwa/J |
| 003451 | 129-Smad3tm1Par/J |
| 003310 | 129S-Gt(ROSA)26Sortm1Sor/J |
| 003383 | 129S-Nogtm1Amc/J |
| 004545 | 129S-Npytm1Rpa/J |
| 005091 | 129S-Pnpla6tm1Blw/J |
| 007199 | 129S-Sgpl1Gt(ROSA)78Sor/J |
| 003082 | 129S1/SvImJ-Bcl2tm1Mpin/J |
| 004478 | B6.129-Foxd1tm1Lai/J |
| 006939 | B6.129-Fut1tm1Sdo/J |
| 005768 | B6.129-Htr5atm1Dgen/J |
| 002938 | B6.129-Kdrtm1Jrt/J |
| 004158 | B6.129-Maftm1Gsb/J |
| 006497 | B6.129-Skiltm2Spw/J |
| 005772 | B6.129P2-Acvrl1tm1Dgen/J |
| 006431 | B6.129P2-Adam21tm1Dgen/J |
| 005770 | B6.129P2-Adamts4tm1Dgen/J |
| 005771 | B6.129P2-Adamts5tm1Dgen/J |
| 005773 | B6.129P2-Adcy3tm1Dgen/J |
| 005774 | B6.129P2-Adcy7tm1Dgen/J |
| 005775 | B6.129P2-Adipor2tm1Dgen/J |
| 005776 | B6.129P2-Avpr1atm1Dgen/J |
| 005777 | B6.129P2-Axltm1Dgen/J |
| 005783 | B6.129P2-Cacna1ctm1Dgen/J |
| 005780 | B6.129P2-Cacna2d3tm1Dgen/J |
| 005781 | B6.129P2-Cacng3tm1Dgen/J |
| 005782 | B6.129P2-Cacng4tm1Dgen/J |
| 005784 | B6.129P2-Capn5tm1Dgen/J |
| 005785 | B6.129P2-Capn7tm1Dgen/J |
| 005792 | B6.129P2-Ccr1l1tm1Dgen/J |
| 005793 | B6.129P2-Ccr6tm1Dgen/J |
| 005794 | B6.129P2-Ccr7tm1Dgen/J |
| 005779 | B6.129P2-Celsr2tm1Dgen/J |
| 005797 | B6.129P2-Chrna2tm1Dgen/J |
| 005787 | B6.129P2-Ctsctm1Dgen/J |
| 005796 | B6.129P2-Cxcr3tm1Dgen/J |
| 005798 | B6.129P2-Drd5tm1Dgen/J |
| 005800 | B6.129P2-Efemp2tm1Dgen/J |
| 005801 | B6.129P2-Esrratm1Dgen/J |
| 005802 | B6.129P2-Faim2tm1Dgen/J |
| 006262 | B6.129P2-Fut2tm1Sdo/J |
| 005803 | B6.129P2-Fzd1tm1Dgen/J |
| 005804 | B6.129P2-Fzd8tm1Dgen/J |
| 005811 | B6.129P2-Gabra3tm1Dgen/J |
| 005812 | B6.129P2-Gabra4tm1Dgen/J |
| 005810 | B6.129P2-Gabrptm1Dgen/J |
| 005809 | B6.129P2-Galr1tm1Dgen/J |
| 005816 | B6.129P2-Glra3tm1Dgen/J |
| 005805 | B6.129P2-Gpr151tm1Dgen/J |
| 005806 | B6.129P2-Gpr37tm1Dgen/J |
| 005807 | B6.129P2-Gpr6tm1Dgen/J |
| 005813 | B6.129P2-Grik5tm1Dgen/J |
| 005808 | B6.129P2-Grk5tm1Dgen/J |
| 005814 | B6.129P2-Grm1tm1Dgen/J |
| 005815 | B6.129P2-Grm3tm1Dgen/J |
| 005817 | B6.129P2-Gsk3btm1Dgen/J |
| 005818 | B6.129P2-Hcrtr1tm1Dgen/J |
| 005767 | B6.129P2-Htr4tm1Dgen/J |
| 005769 | B6.129P2-Htr7tm1Dgen/J |
| 005830 | B6.129P2-Kcnq2tm1Dgen/J |
| 005821 | B6.129P2-Lats2tm1Dgen/J |
| 005822 | B6.129P2-Lmbr1tm1Dgen/J |
| 005850 | B6.129P2-Mapkapk2tm1Dgen/J |
| 005824 | B6.129P2-Mmp17tm1Dgen/J |
| 005825 | B6.129P2-Mtmr1tm1Dgen/J |
| 005778 | B6.129P2-Naip1tm1Dgen/J |
| 005826 | B6.129P2-Ntsr1tm1Dgen/J |
| 005829 | B6.129P2-Pkd2l2tm1Dgen/J |
| 005828 | B6.129P2-Ppardtm1Dgen/J |
| 005831 | B6.129P2-Ppm1ftm1Dgen/J |
| 005827 | B6.129P2-Ptch2tm1Dgen/J |
| 005832 | B6.129P2-Ptprotm1Dgen/J |
| 005799 | B6.129P2-S1pr4tm1Dgen/J |
| 005837 | B6.129P2-Scn11atm1Dgen/J |
| 005836 | B6.129P2-Scn9atm1Dgen/J |
| 005834 | B6.129P2-Sema5atm1Dgen/J |
| 005835 | B6.129P2-Sema6ctm1Dgen/J |
| 006432 | B6.129P2-Slc18a1tm1Dgen/J |
| 005839 | B6.129P2-Slc22a12tm1Dgen/J |
| 005838 | B6.129P2-Slc22a6tm1Dgen/J |
| 005840 | B6.129P2-Slc40a1tm1Dgen/J |
| 005841 | B6.129P2-Slc6a9tm1Dgen/J |
| 005842 | B6.129P2-Slc7a8tm1Dgen/J |
| 005843 | B6.129P2-Slc9a6tm1Dgen/J |
| 005844 | B6.129P2-Sstr1tm1Dgen/J |
| 005847 | B6.129P2-Tgfbr1tm1Dgen/J |
| 005845 | B6.129P2-Thbs4tm1Dgen/J |
| 005790 | B6.129P2-Tpp1tm1Dgen/J |
| 005848 | B6.129P2-Trpm5tm1Dgen/J |
| 005791 | B6.129P2-Xcr1tm1Dgen/J |
| 003474 | B6.129S4-Gt(ROSA)26Sortm1Sor/J |
| 005901 | B6.129S4-Ppardtm2Rev/J |
| 006142 | B6.129S4-Ppargtm1Rev/J |
| 003754 | B6.129S4-Shroom3Gt(ROSA)53Sor/J |
| 005119 | B6.129S6-Npas2tm1Slm/J |
| 002741 | B6.129S7-Alpltm1Sor/J |
| 005970 | B6.129S7-Atoh1tm2Hzo/J |
| 006039 | B6.129S7-Efnb2tm1And/J |
| 002192 | B6.129S7-Gt(ROSA)26Sor/J |
| 005981 | B6.129S7-Rai1tm1Jrl/J |
| 005039 | B6.129X1-Adra1atm1Pcs/J |
| 005085 | B6.Cg-Cd44tm1Hbg/J |
| 007745 | B6.Cg-Mirn155tm1.1Rsky/J |
| 005317 | B6.Cg-Tg(BAT-lacZ)3Picc/J |
| 004178 | B6.Cg-Tg(CAG-Bgeo/GFP)21Lbe/J |
| 006477 | B6.Cg-Tg(CAG-lacZ-WGA)330Bbm/J |
| 003139 | B6.Cg-Tg(DBHn-lacZ)8Rpk/J |
| 006229 | B6.Cg-Tg(DRE-lacZ)2Gswz/J |
| 002982 | B6.Cg-Tg(xstpx-lacZ)32And/J |
| 003504 | B6;129-Gt(ROSA)26Sortm1Sho/J |
| 005064 | B6;129-Slc30a3tm1Rpa/J |
| 005788 | B6;129P2-Cd97tm1Dgen/J |
| 005833 | B6;129P2-Rgs4tm1Dgen/J |
| 002073 | B6;129S-Gt(ROSA)26Sor/J |
| 006470 | B6;129S-Hopxtm1Eno/J |
| 004153 | B6;129S-Mtap7Gt(ROSABetageo)1Sor/J |
| 006958 | B6;129S-Nkd1tm1Kwha/J |
| 006960 | B6;129S-Nkd2tm1Kwha/J |
| 007204 | B6;129S4-2610005L07RikGt(ROSA)73Sor/J |
| 003309 | B6;129S4-Gt(ROSA)26Sortm1Sor/J |
| 004365 | B6;129S6-Srebf1tm1Mbr/J |
| 002317 | B6;129S7-Alpltm1Sor/J |
| 003266 | B6;129S7-Epas1tm1Rus/J |
| 006044 | B6;129S7-Ephb4tm1And/J |
| 003471 | B6;C3H-Tg(CNP-GEO)1Ldh/J |
| 006465 | B6;CBA-Tg(CAG-lacZ-WGA)330Bbm/J |
| 006680 | B6;CBA-Tg(Olfr16*,taulacZ)19Mom/MomJ |
| 006671 | B6;CBA-Tg(Olfr16*,taulacZ)5Mom/MomJ |
| 006672 | B6;CBA-Tg(Olfr16*,taulacZ)7Mom/MomJ |
| 006673 | B6;CBA-Tg(Olfr16,taulacZ)sn2Mom/MomJ |
| 004141 | B6;CBA-Tg(UAS-lacZ)65Rth/J |
| 002369 | B6;SJL-Tg(c177-lacZ)226Bri/J |
| 002372 | B6;SJL-Tg(c177-lacZ)227Bri/J |
| 002621 | B6;SJL-Tg(tetop-lacZ)2Mam/J |
| 003299 | B6;SWJ-Tg(TIMP3-lacZ)7Jeb/J |
| 002865 | B6CBA-Tg(Wnt1-lacZ)206Amc/J |
| 002955 | C.129S7-Gt(ROSA)26Sor/J |
| 002754 | C57BL/6-Tg(LacZpl)60Vij/J |
| 002193 | C57BL/6J-Tg(MTn-lacZ)204Bri/J |
| 002981 | DBA/2-Tg(xstpx-lacZ)36And/J |
| 004127 | FVB-Tg(Nes-rtTA)306Rvs/J |
| 007225 | FVB.129(B6)-Usp18tm1Dzh/J |
| 008203 | FVB.Cg-Smn1tm1Msd Tg(ACTA1-SMN)63Ahmb Tg(SMN2)89Ahmb/J |
| 008209 | FVB.Cg-Smn1tm1Msd Tg(ACTA1-SMN)69Ahmb Tg(SMN2)89Ahmb/J |
| 006214 | FVB.Cg-Smn1tm1Msd/J |
| 005024 | FVB.Cg-Tg(SMN2)89Ahmb Smn1tm1Msd/J |
| 005026 | FVB.Cg-Tg(SMN2)89Ahmb Tg(SMN1*A2G)2023Ahmb Smn1tm1Msd/J |
| 005025 | FVB.Cg-Tg(SMN2*delta7)4299Ahmb Tg(SMN2)89Ahmb Smn1tm1Msd/J |
| 003140 | FVB/N-Tg(PAI1-lacZ)1Jjb/J |
| 002856 | FVB/N-Tg(TIE2-lacZ)182Sato/J |
| 005941 | FVB/N-Tg(tetO-Aurkb,lacZ)41Kra/J |
| 003315 | FVB/N-Tg(tetORo1-lacZ)3Conk/J |
| 003487 | FVB/NJ-Tg(XGFAP-lacZ)3Mes/J |
| 005878 | NOD.Cg-Cd44tm1Hbg/J |
| 003899 | STOCK Cd44tm1Hbg/J |
| 006241 | STOCK Hhiptm1Amc/J |
| 006578 | STOCK Myoz2tm1Eno/J |
| 005707 | STOCK Rag1tm1Mom Tg(TIE2-lacZ)182Sato/J |
| 008212 | STOCK Smn1tm1Msd Tg(Prnp-SMN)92Ahmb Tg(SMN2)89Ahmb/J |
| 006882 | STOCK Tg(CAG-Bgeo,-AML1/ETO,-ALPP)1Lbe/J |
| 005438 | STOCK Tg(CAG-Bgeo,-DsRed*MST)1Nagy/J |
| 006850 | STOCK Tg(CAG-Bgeo,-NOTCH1,-EGFP)1Lbe/J |
| 006876 | STOCK Tg(CAG-Bgeo,-TEL/AML1,-EGFP)A6Lbe/J |
| 006613 | STOCK Tg(CAG-Bgeo,-Tle1,-ALPP)1Lbe/J |
| 003919 | STOCK Tg(CAG-Bgeo/ALPP)1Lbe/J |
| 003920 | STOCK Tg(CAG-Bgeo/GFP)21Lbe/J |
| 004623 | STOCK Tg(Fos-lacZ)34Efu/J |
| 006674 | STOCK Tg(Olfr16,taulacZ)2030Mom/MomJ |
| 005493 | STOCK Tg(Tek-rtTA,TRE-lacZ)1425Tpr/J |
| 002395 | STOCK Tg(Zfy1-lacZ)218Bri/J |
| 003274 | STOCK Tg(tetNZL)2Bjd/J |
| 005728 | STOCK Tg(tetO-Ipf1,lacZ)958.1Macd/J |
View lacZ Expression Strains (174 strains)
Strains carrying Tg(CAG-Bgeo,-DsRed*MST)1Nagy allele
View Strains carrying Tg(CAG-Bgeo,-DsRed*MST)1Nagy (1 strain)
Strains carrying other alleles of ACTB
View Strains carrying other alleles of ACTB (7 strains)
Strains carrying other alleles of Bgeo
View Strains carrying other alleles of Bgeo (9 strains)
Strains carrying other alleles of DsRed
View Strains carrying other alleles of DsRed (5 strains)
Additional Web Information
Congenic Nomenclature
Cre-lox or FLP-FRT Systems
Fluorescent Proteins/lacZ Systems
Animal Health Reports
Room Number AX12
Research Applications
This mouse can be used to support research in many areas including:
Research Tools
lacZ Expression
Cre-lox System
(loxP-flanked Sequences: Test/Reporter)
Developmental Biology Research
(Cre-lox System)
Fluorescent Proteins
Genetics Research
(Tissue/Cell Markers: Cre-lox System)
Bgeo related
Research Tools
lacZ Expression
DsRed related
Fluorescent Proteins
References
Selected Reference(s)
Vintersten K; Monetti C; Gertsenstein M; Zhang P; Laszlo L; Biechele S; Nagy A. 2004. Mouse in red: red fluorescent protein expression in mouse ES cells, embryos, and adult animals. Genesis
40(4):241-6.
[PubMed: 15593332]
[MGI Ref ID J:109837]
Price and Supply Information
| Strain Name: |
B6.Cg-Tg(CAG-Bgeo,-DsRed*MST)1Nagy/J |
| Stock Number: |
006055 |
Price Details
IMPORTANT NOTE: Prices are based on shipping destination.
The shipping destinations are:
*Pricing for Shipping Destination selected:
International
| Price(s) in US dollars ($) | Genotype(s) Provided |
| Individual Mouse Price | $307.40 | Hemizygous for Tg(CAG-Bgeo,-DsRed*MST)1Nagy | | |
| Pair | $375.30 | Hemizygous for Tg(CAG-Bgeo,-DsRed*MST)1Nagy x Noncarrier | | |
| Pair | $375.30 | Noncarrier x Hemizygous for Tg(CAG-Bgeo,-DsRed*MST)1Nagy | | |
Supply Details
| Standard Supply | Repository-Live. A collection of over 1000 strains maintained as live colonies. Individual colonies are sized to meet current customer demand. Delivery for orders of 10 mice or less ranges on average from one to eight weeks; mice are generally shipped between four to six weeks of age with a maximum shipping age of ~nine weeks. Colony sizes do not generally support stringent age specifications for large volumes of mice; however custom orders and larger quantities of mice are easily arranged. Estimated ship dates for all orders provided within 48 hours of order placement. |
| Supply Notes |
Histology and Tissue Collection Services are available for all JAX® Mice strains. For more information, please contact Customer Service at orderquest@jax.org or 1-207-288-5845.
Usually shipped between four and eight weeks of age.
This strain is included in the Induced Mutant Resource Colony collection.
Genomic DNA is available for this strain from the Mouse DNA Resource.
|
| Licensing | See General Terms and Conditions below
for Licensing and Use Restrictions
|
| Control Information | View Control Information in Strain Details.
View Control Pricing Information for JAX® Strains. |
General Terms and Conditions
View
JAX® Mice & Services Conditions of Use.
Effective September 26, 2007: License Requirements for Strains using Cre-lox Technology only apply in Canada, see Licenses for Strains using Cre-lox Technology.
For additional Licensing and Use Restrictions view the link(s) below:
- Use of MICE by companies or for-profit entities requires a license prior to shipping.
The Jackson Laboratory's Genotype Promise
The Jackson Laboratory has rigorous genetic quality control and mutant gene
genotyping programs to ensure the genetic background of JAX
® Mice strains as
well as the genotypes of strains with identified molecular mutations.
JAX
® Mice strains are only made available to researchers after meeting our
standards. However, the phenotype of each strain may not be fully
characterized and/or captured in the strain data sheets.
Therefore, we
cannot guarantee a strain's phenotype will meet all expectations. To
ensure that JAX
® Mice will meet the needs of individual research projects
or when requesting a strain that is new to your research, we suggest ordering
and performing tests on a small number of mice to determine suitability for
your particular project.
Ordering and Purchasing Information
Purchasing Information
JAX® Mice Orders
Surgical Services
Contact Information
Orders & Technical Support
Tel: 800.422.6423 or 207.288.5845
Fax: 207.288.6150
Technical Support Email Form
Go to JAX® Mice Query Form