Strain Name: |
B6.BKS-(D12Mit182-D12Mit2)/Pgn |
|---|---|
Stock Number: |
006056 |
Availability: | Repository-Cryopreserved |
General Terms and Conditions |
| Strain Common Names | Ath6; |
| Genes & Alleles | Ath6; Ath6C57BLKS/J; D12Mit182; D12Mit2; ; |
Product Information
Strain Details
Type JAX® GEMM® Strain - Congenic Additional information on JAX® GEMM® Strains. Type JAX® GEMM® Strain - Mutant Strain Species laboratory mouse Background Strain C57BL/6J Donor Strain C57BLKS/J H2 Haplotype b Generation N11F4p Appearance
black
Related Genotype: a/aStrain Description
The QTL, atherosclerosis 6, is thought to be located in the congenic region between D12Mit182 and D12Mit105.Strain Development
The region (D12Mit182-D12Mit2) has been introgressed from C57BLKS/J to C57BL/6J for a minimum of 11 generations. Additional genotyping in the congenic region indicates that the interval defined by (D12Mit182-D12Mit105) is DBA/2J-like and the interval defined by (D12Mit83-D12Mit60) is C57BL/6J-like. The inbred strain C57BLKS/J originated from the inbred strains C57BL/6J and DBA/2J. Dr. Beverly Paigen generated this strain at The Jackson Laboratory; the strain was cryopreserved in 2006.
Gene & Allele Details
| Gene Symbol and Name | D12Mit182, DNA segment, Chr 12, Massachusetts Institute of Technology 182 | ||
|---|---|---|---|
| Chromosome | 12 | ||
| Gene Symbol and Name | D12Mit2, DNA segment, Chr 12, Massachusetts Institute of Technology 2 | ||
| Chromosome | 12 | ||
| Allele Symbol | Ath6C57BLKS/J | ||
| Allele Name | C57BLKS/J | ||
| Strain of Origin | C57BLKS/J | ||
| Gene Symbol and Name | Ath6, atherosclerosis 6 | ||
| Chromosome | 12 | ||
Control Information
| Control | ||
|---|---|---|
| 000664 C57BL/6J | ||
| Considerations for Choosing Controls | ||
Related Strains
Strains carrying Ath6C57BLKS/J allele
007224 B6.Cg-Apoetm1Unc(D12Mit182-D12Mit2)/Pgn View Strains carrying Ath6C57BLKS/J (1 strain)
Additional Web Information
Congenic Nomenclature
Research Applications
This mouse can be used to support research in many areas including:
Cardiovascular Research
Atherosclerosis
Research Tools
Genetics Research (Gene Mapping: Tools for QTL Mapping, Segregation and Linkage Analysis)
References
Additional ReferencesPrice and Supply Information
| Strain Name: | B6.BKS-(D12Mit182-D12Mit2)/Pgn |
| Stock Number: | 006056 |
Price Details
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Supply Details
| Standard Supply | Repository-Cryopreserved. Must Be Recovered. Please refer to pricing and supply notes for further information. |
|---|---|
| Supply Notes |
Cryopreserved Embryos This strain is also available as cryopreserved embryos from our Repository. Orders for cryopreserved embryos are supplied subject to a signed agreement that must be returned to the Customer Service Department after order placement. Experienced technicians at The Jackson Laboratory have recovered frozen embryos of this strain successfully. We will provide you enough embryos to perform two embryo transfers. The Jackson Laboratory does not guarantee successful recovery at your facility. For complete information on purchasing embryos from our repository, please visit our Cryopreserved Embryos web page. Cryorecovery - Standard. The recovery process begins when a signed agreement form is returned to the Customer Service Department after order placement. Although results vary by strain, at least two males and two females (two pairs) will be provided, typically within 15 weeks of our receipt of the signed agreement form. If the first recovery attempt is unsuccessful or only one pair is recovered, a second recovery will be done, extending the delivery time to approximately 25 weeks. At least one member of each pair will be of known genotype and will carry the mutation if it is a mutant strain. Please note that pairs may not reflect the mating scheme utilized by The Jackson Laboratory prior to cryopreservation of the strain. Mating schemes are sometimes modified for successful cryopreservation. Price represents a repository maintenance fee, which includes the cost of recovery of the strain from the cryopreservation resource and the periodic replacement of the frozen embryos used for recovery. Cryorecovery to establish a Dedicated Supply for greater quantities of mice. |
| Licensing | See General Terms and Conditions below |
| Control Information | View Control Information in Strain Details. |
General Terms and Conditions
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The Jackson Laboratory's Genotype Promise
The Jackson Laboratory has rigorous genetic quality control and mutant gene genotyping programs to ensure the genetic background of JAX® Mice strains as well as the genotypes of strains with identified molecular mutations. JAX® Mice strains are only made available to researchers after meeting our standards. However, the phenotype of each strain may not be fully characterized and/or captured in the strain data sheets. Therefore, we cannot guarantee a strain's phenotype will meet all expectations. To ensure that JAX® Mice will meet the needs of individual research projects or when requesting a strain that is new to your research, we suggest ordering and performing tests on a small number of mice to determine suitability for your particular project.Ordering and Purchasing Information
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