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Strain Common Names	B6.D2-Chr13D;
Genes & Alleles	D13Mit314;   D13Mit35;   ;

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Product Information

Strain Details

Type JAX® GEMM® Strain - Congenic Additional information on JAX® GEMM® Strains. Species laboratory mouse H2 Haplotype b Generation ?+F4 (06-DEC-07)

Appearance
black
Related Genotype: a/a

Strain Description
This C57BL/6J congenic carries the distal portion of chromosome 13 from DBA/2J. The Mit or SNP (rs) markers in the strain name define the congenic interval.

Marker-assisted breeding was used to construct a set of overlapping congenic strains called genome-tagged mice (GTM) that span the entire mouse genome. Each member of the panel carries an average of a 23 cM segment (range 8 to 58 cM) from DBA/2J introgressed on to a C57BL/6J background. The segments represent the distal (D), middle (M), and proximal (P) portions of all or most of a given chromosome. (Iakoubova OA, et. al., 2001) GTM are a valuable resource for mapping and confirmation of loci contributing to complex traits.

The Jackson Laboratory is working with Dr. Lusis' group to import and make available additional strains in the panel.

Gene & Allele Details

Gene Symbol and Name		D13Mit35, DNA segment, Chr 13, Massachusetts Institute of Technology 35
Chromosome		13
Gene Symbol and Name		D13Mit314, DNA Segment, Chr 13 Massachusetts Institute of Technology 314
Chromosome		13

Control Information

	Control
	000664 C57BL/6J
Considerations for Choosing Controls

Colony Maintenance

Diet Information	LabDiet® 5K52/5K67

Additional Web Information

Congenic Nomenclature

Research Applications

This mouse can be used to support research in many areas including:

Research Tools
Genetics Research (Gene Mapping: Tools for QTL Mapping, Segregation and Linkage Analysis)

References

Selected Reference(s)

Davis RC; Schadt EE; Smith DJ; Hsieh EW; Cervino AC; van Nas A; Rosales M; Doss S; Meng H; Allayee H; Lusis AJ. 2005. A genome-wide set of congenic mouse strains derived from DBA/2J on a C57BL/6J background. Genomics 86(3):259-70. [PubMed: 16039824]  [MGI Ref ID J:107521]

Iakoubova OA; Olsson CL; Dains KM; Ross DA; Andalibi A; Lau K; Choi J; Kalcheva I; Cunanan M; Louie J; Nimon V; Machrus M; Bentley LG; Beauheim C; Silvey S; Cavalcoli J; Lusis AJ; West DB. 2001. Genome-tagged mice (GTM): two sets of genome-wide congenic strains. Genomics 74(1):89-104. [PubMed: 11374905]  [MGI Ref ID J:69881]

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Price and Supply Information

Strain Name:	B6.D2-(D13Mit314-D13Mit35)/1LusJ
Stock Number:	006061

 

This strain is currently Under Development for Cryopreservation Repository.
To register your interest in this strain go to the Strain Interest Form.

Estimated Available for Sale Date:

Please note: Estimated available for sale dates are provided to keep customers better informed on strains under development. Please note that our Colony Managers routinely monitor the target date and edit it based on breeding performance and other factors. The length of time it takes to make a new strain available for sale depends on genotype, age, number of animals sent by the Donating Investigator, breeding performance, additional strain development (backcrossing, making homozygous), and anticipated demand for the strain/interest registered.

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Supply Details

Standard Supply	Under Development for Cryopreservation Repository
Supply Notes	This strain is included in the Mouse Mutant Resource collection.
Licensing	See General Terms and Conditions below for Licensing and Use Restrictions
Control Information	View Control Information in Strain Details.

General Terms and Conditions

View JAX^® Mice & Services Conditions of Use.

For additional Licensing and Use Restrictions view the link(s) below:
- Use of MICE by companies or for-profit entities requires a license prior to shipping.

The Jackson Laboratory's Genotype Promise

The Jackson Laboratory has rigorous genetic quality control and mutant gene genotyping programs to ensure the genetic background of JAX^® Mice strains as well as the genotypes of strains with identified molecular mutations. JAX^® Mice strains are only made available to researchers after meeting our standards. However, the phenotype of each strain may not be fully characterized and/or captured in the strain data sheets. Therefore, we cannot guarantee a strain's phenotype will meet all expectations. To ensure that JAX^® Mice will meet the needs of individual research projects or when requesting a strain that is new to your research, we suggest ordering and performing tests on a small number of mice to determine suitability for your particular project.

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