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- Description
- Phenotype
- Genes & alleles
- Genotyping
- Health & husbandry
- References
- Purchasing information
- Terms of Use
Description
Strain Information
Type Consomic; Additional information on Consomic Mice. Type Congenic; Additional information on Genetically Engineered and Mutant Mice. Visit our online Nomenclature tutorial. Additional information on Congenic nomenclature. Mating System Homozygote x Hemizygote (Female x Male) 03-JUN-08 Species laboratory mouse Background Strain C57BL/6J Donor Strain PWD/Ph H2 Haplotype b Generation ?+F12 (11-JUL-11)
Generation DefinitionsAppearance
black
Related Genotype: a/aDescription
This strain represents one of a panel of inter-species chromosome substitution (or consomic) strains (IC-ISS). Each strain carries a chromosome from the Mus musculus musculus wild-derived strain PWD/Ph introgressed into a Mus musculus domesticus C57BL/6J background. The two species are believed to have diverged 350,000 to one million years ago and exhibit multiple genetic and phenotypic differences. The strain set also includes a conplastic strain (mtPWD/Ph) created by sequential backcrossing of the donor female to the host male. A conplastic strain carries the mitochondrial genome of the donor strain. The IC-ISS strains represent a tool for dissection of quantitative trait loci.Development
Dr. Jiri Forejt from The Institute of Molecular Genetics, Prague, Czech Republic developed the C57BL/6J-Chr #PWD/Ph/ForeJ strain set by replacing the individual chromosomes from the PWD/Ph donor strain into the C57BL/6J host strain using a marker-assisted series of backcrosses. The Chromosome X consomic is a partial consomic. Chr X.3PWD/Ph indicates that the distal (d) portion of Chromosome X is from the PWD/Ph donor strain. The set was donated to The Jackson Laboratory in 2005.
Related Strains
B6/PWD Consomic Panel
007600 C57BL/6J-Chr 10.1PWD/Ph/ForeJ 007601 C57BL/6J-Chr 10.2PWD/Ph/ForeJ 006599 C57BL/6J-Chr 10.3PWD/Ph/ForeJ 005997 C57BL/6J-Chr 11.1PWD/Ph/ForeJ 005998 C57BL/6J-Chr 11.2PWD/Ph/ForeJ 006372 C57BL/6J-Chr 11.3PWD/Ph/ForeJ 005263 C57BL/6J-Chr 12PWD/Ph/ForeJ 005519 C57BL/6J-Chr 13PWD/Ph/ForeJ 005264 C57BL/6J-Chr 14PWD/Ph/ForeJ 005265 C57BL/6J-Chr 15PWD/Ph/ForeJ 005266 C57BL/6J-Chr 16PWD/Ph/ForeJ 005267 C57BL/6J-Chr 17PWD/Ph/ForeJ 005268 C57BL/6J-Chr 18PWD/Ph/ForeJ 005269 C57BL/6J-Chr 19PWD/Ph/ForeJ 005259 C57BL/6J-Chr 1PWD/Ph/ForeJ 005995 C57BL/6J-Chr 2PWD/Ph/ForeJ 005518 C57BL/6J-Chr 3PWD/Ph/ForeJ 006226 C57BL/6J-Chr 4PWD/Ph/ForeJ 005260 C57BL/6J-Chr 5PWD/Ph/ForeJ 005261 C57BL/6J-Chr 6PWD/Ph/ForeJ 005996 C57BL/6J-Chr 7PWD/Ph/ForeJ 006597 C57BL/6J-Chr 8PWD/Ph/ForeJ 005262 C57BL/6J-Chr 9PWD/Ph/ForeJ 005762 C57BL/6J-Chr X.1PWD/Ph/ForeJ 006598 C57BL/6J-Chr X.2PWD/Ph/ForeJ 005270 C57BL/6J-Chr YPWD/Ph/ForeJ 005761 C57BL/6J-mtPWD/Ph/ForeJ View B6/PWD Consomic Panel (27 strains)
Additional Web Information
JAX® NOTES, Fall 2006; 503. C57BL/6J Chr#PWD/Ph/ForeJ Consomic Strain Panel Available from The Jackson Laboratory
Phenotype
Phenotype Information
Mouse Phenome Database
This mouse can be used to support research in many areas including:
Research Tools
Genetics Research
Gene Mapping
Gene Mapping: Tools for QTL Mapping, Segregation and Linkage Analysis
Genes & Alleles
Gene & Allele Information provided by MGI
Currently there are no related genes or alleles for this strain.References
References provided by MGI
Selected Reference(s)
Gregorova S; Divina P; Storchova R; Trachtulec Z; Fotopulosova V; Svenson KL; Donahue LR; Paigen B; Forejt J. 2008. Mouse consomic strains: Exploiting genetic divergence between Mus m. musculus and Mus m. domesticus subspecies. Genome Res :. [PubMed: 18256238] [MGI Ref ID J:130871]
Health & husbandry
Health & Colony Maintenance Information
Animal Health Reports
Room Number AX11
Colony Maintenance
Mating System Homozygote x Hemizygote (Female x Male) 03-JUN-08 Diet Information LabDiet® 5K52/5K67
Purchasing information
Pricing, Supply Level & Notes, Controls
| Pricing for USA, Canada and Mexico shipping destinations |
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Live Mice
Price (US dollars $) Gender Genotypes Provided Individual Mouse $110.00 Male Hemizygous $110.00 Female Homozygous
Pairs /Price (US dollars $) Pair Genotype $220.00 Homozygous x Hemizygous Standard Supply
Repository-Live. The Repository Strains represent an exclusive set of over 1500 unique mouse models maintained at The Jackson Laboratory to support a vast array of research areas. The breeding colonies for Repository Strains provide mice for both large and small orders and fluctuate in size depending on current demand for each strain. We treat orders for these strains as custom orders. Within 2 business days, we respond to each availability inquiry or order with various delivery options. Repository Strains typically are delivered at 4 to 8 weeks of age and will not exceed 12 weeks of age on the day of shipping.
| Pricing for International shipping destinations |
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Live Mice
Price (US dollars $) Gender Genotypes Provided Individual Mouse $143.00 Male Hemizygous $143.00 Female Homozygous
Pairs /Price (US dollars $) Pair Genotype $286.00 Homozygous x Hemizygous Standard Supply
Repository-Live. The Repository Strains represent an exclusive set of over 1500 unique mouse models maintained at The Jackson Laboratory to support a vast array of research areas. The breeding colonies for Repository Strains provide mice for both large and small orders and fluctuate in size depending on current demand for each strain. We treat orders for these strains as custom orders. Within 2 business days, we respond to each availability inquiry or order with various delivery options. Repository Strains typically are delivered at 4 to 8 weeks of age and will not exceed 12 weeks of age on the day of shipping.
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Standard Supply
Repository-Live. The Repository Strains represent an exclusive set of over 1500 unique mouse models maintained at The Jackson Laboratory to support a vast array of research areas. The breeding colonies for Repository Strains provide mice for both large and small orders and fluctuate in size depending on current demand for each strain. We treat orders for these strains as custom orders. Within 2 business days, we respond to each availability inquiry or order with various delivery options. Repository Strains typically are delivered at 4 to 8 weeks of age and will not exceed 12 weeks of age on the day of shipping.
General Supply Notes
- This strain is included in the Special Mutant Stock Resource collection.
- Genomic DNA is available for this strain from the Mouse DNA Resource.
Payment Terms and Conditions
Terms are granted by individual review and stated on the customer invoice(s) and account statement. These transactions are payable in U.S. currency within the granted terms. Payment for services, products, shipping containers, and shipping costs that are rendered are expected within the payment terms indicated on the invoice or stated by contract. Invoices and account balances in arrears of stated terms may result in The Jackson Laboratory pursuing collection activities including but not limited to outside agencies and court filings.
See Terms of Use tab for General Terms and Conditions
The Jackson Laboratory's Genotype Promise
The Jackson Laboratory has rigorous genetic quality control and mutant gene genotyping programs to ensure the genetic background of JAX® Mice strains as well as the genotypes of strains with identified molecular mutations. JAX® Mice strains are only made available to researchers after meeting our standards. However, the phenotype of each strain may not be fully characterized and/or captured in the strain data sheets. Therefore, we cannot guarantee a strain's phenotype will meet all expectations. To ensure that JAX® Mice will meet the needs of individual research projects or when requesting a strain that is new to your research, we suggest ordering and performing tests on a small number of mice to determine suitability for your particular project.Ordering Information
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