Strain Name: |
C3HeB.SW-Soaa/MonJ |
|---|---|
Stock Number: |
006435 |
Availability: | Repository- Live |
General Terms and Conditions |
| Genes & Alleles | Pde6b; Pde6brd1; Soa; Soaa; |
Type JAX® GEMM® Strain - Congenic Additional information on JAX® GEMM® Strains. Type JAX® GEMM® Strain - Mutant Strain Mating System Homozygote x Homozygote (Female x Male) Species laboratory mouse Background Strain C3HeB/FeJ Donor Strain SWR/J H2 Haplotype k Generation ?+F2 (05-DEC-07) Appearance
agouti
Related Genotype: A/AStrain Description
Mice homozygous for the dominant a allele exhibit an taster (avoidance as low as <.001mM concentration) phenotype to the bitter compound sucrose octaacetate. This strain may be useful in studies related to the mechanisms of taste.Strain Development
This congenic was created in the laboratory of Dr. Glayde Whitney at Florida State University in 1994 by introgressing the SWR/J "taster" allele into the C3HeB/FeJ "demitaster" background for at least 12 generations. Mice were tested for avoidance of (a allele) or indifference to (c allele) a 0.1 mM sodium octaacetate (SOA) solution. The colony was maintained by backcrossing for additional 20 generations. In 1999, the colony was transferred to the Monell Chemical Senses Center and backcrossed for another 10 generations. After 40 generations, mice were intercrossed to generate a homozygous colony. The strain was donated to The Jackson Laboratory Repository in 2006 by Dr. Alexander Bachmanov.
Mammalian Phenotype Terms assigned by genotype |
| Allele Symbol | Pde6brd1 | ||
|---|---|---|---|
| Allele Name | retinal degeneration 1 | ||
| Common Name(s) | rd; rd-1; rd1; rodless retina; | ||
| Allele Symbol | Soaa | ||
| Allele Name | sucrose octaacetate aversion, a variant | ||
| Common Name(s) | SOA taster; aversion; | ||
| Gene Symbol and Name | Soa, sucrose octaacetate aversion | ||
| Chromosome | 6 | ||
| General Note | Alleles in dominance order are : a allele - taster (avoidance at <1mM concentration) in SWR/J; b allele - nontaster (no avoidance) in BDP/J, C57BL/6J, C57BR/cdJ, C57L/J, SJL/J and 129/J; c allele - demitaster (avoidance near saturation) in ABP/Le, AKR/J,BALB/cByJ, BALB/cJ, C3HeB/FeJ, C3H/HeJ, DBA/2J, LP/J, NZB/BINJ, PL/J and RF/J. J:3143 | ||
| Diet Information | LabDiet® 5K52/5K67 |
|---|
Strains carrying Pde6brd1 allele
View Strains carrying Pde6brd1 (74 strains)
Strains carrying other alleles of Pde6b
004297 B6.CXB1-Pde6brd10/J 002802 C3.BLiA Pde6b+-Krd/J 001979 C3A.BLiA-Pde6b+.O20-Prph2Rd2/J 001912 C3A.BLiA-Pde6b+/J 003648 C3Sn.BLiA-Pde6b+/Dn 004766 C57BL/6J-Pde6brd1-2J/J 004828 FVB.129P2-Pde6b+ Tyrc-ch/AntJ 004808 STOCK Mapttm1(EGFP)Klt Tg(MAPT)8cPdav/J View Strains carrying other alleles of Pde6b (8 strains)
Strains carrying other alleles of Soa
004770 SW.B6-Soab/J View Strains carrying other alleles of Soa (1 strain)
Congenic Nomenclature
Room Number FGB29
Pde6brd1 relatedSensorineural Research
Taste Defects
Mouse/Human Gene Homologs
retinitis pigmentosa, autosomal recessive
Sensorineural Research
Retinal Degeneration
Selected Reference(s)
Additional ReferencesBachmanov AA; Li X; Li S; Neira M; Beauchamp GK; Azen EA. 2001. High-resolution genetic mapping of the sucrose octaacetate taste aversion (Soa) locus on mouse Chromosome 6. Mamm Genome 12(9):695-9. [PubMed: 11641717] [MGI Ref ID J:71412]
Boughter JD Jr; Whitney G. 1995. C3.SW-Soaa heterozygous congenic taster mice. Behav Genet 25(3):233-7. [PubMed: 7598666] [MGI Ref ID J:25226]
| Strain Name: | C3HeB.SW-Soaa/MonJ |
| Stock Number: | 006435 |
IMPORTANT NOTE: Prices are based on shipping destination. To view prices, select your shipping destination.
| Standard Supply | Repository-Live. A collection of over 1000 strains maintained as live colonies. Individual colonies are sized to meet current customer demand. Delivery for orders of 10 mice or less ranges on average from one to eight weeks; mice are generally shipped between four to six weeks of age with a maximum shipping age of ~nine weeks. Colony sizes do not generally support stringent age specifications for large volumes of mice; however custom orders and larger quantities of mice are easily arranged. Estimated ship dates for all orders provided within 48 hours of order placement. |
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| Supply Notes |
Usually shipped between four and eight weeks of age. This strain is included in the Mouse Mutant Resource collection. Genomic DNA is available for this strain from the Mouse DNA Resource. |
| Licensing | See General Terms and Conditions below |
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