Strain Name:

C57BL/6-Tg(CAG-EGFP)131Osb/LeySopJ

Stock Number:

006567

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Availability:

Repository- Live

GFP labels all cells in this strain, with the exception of erythrocytes and hair.

Description

Strain Information

Former Names C57BL/6-Tg(ACTB-EGFP)131Osb/LeySopJ    (Changed: 08-MAY-08 )
B6.Cg-Tg(ACTB-EGFP)1Osb/LeySopJ    (Changed: 17-OCT-07 )
C57BL/6-Tg(ACTB-EGFP)1Osb/LeySopJ    (Changed: 03-MAY-07 )
C57BL/6-Tg(CAGG-EGFP)1Ley/J    (Changed: 03-MAY-07 )
Type Coisogenic; Mutant Strain; Transgenic;
Additional information on Genetically Engineered and Mutant Mice.
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Mating System+/+ sibling x Hemizygote         (Female x Male)   02-MAY-08
Specieslaboratory mouse
Generation?+NE4F2 (17-MAY-13)
Generation Definitions
 
Donating Investigator Brian Soper,   The Jackson Laboratory

Description
This transgenic mouse line with an "enhanced" GFP (EGFP) cDNA under the control of a chicken beta-actin promoter and cytomegalovirus enhancer makes all of the tissues, with the exception of erythrocytes and hair, appear green under excitation light. The viability of homozygous mice is unknown.

Of note, it has been the experience at The Jackson Laboratory that Stock No. 006567 (C57BL/6-Tg(CAG-EGFP)131Osb/LeySopJ) demonstrates the highest proportion of GFP expressing cell populations in bone marrow, thymus, spleen and peripheral blood when compared to Stock No. 003291 (C57BL/6-Tg(CAG-EGFP)1Osb/J) and Stock No. 007075 (CByJ.B6-Tg(CAG-EGFP)1Osb/J).

View the pdf document on GFP Expressing Lymphocyte Populations in C57BL/6-Tg(CAG-EGFP)1Osb/J, C57BL/6-Tg(CAG-EGFP)131Osb/LeySopJ and CByJ.B6-Tg(CAG-EGFP)1Osb/J.

Development
The EcoRI sites included in the PCR primers were used to introduce the amplified EGFP cDNA into a pCAGGS expression vector containing the chicken beta-actin promoter and cytomegalovirus enhancer, beta-actin intron and bovine globin poly-adenylation signal. The entire insert with the promoter and coding sequence was excised with Bam-HI and SalI and gel-purified. The transgenic construct was was introduced into C57BL/6 donor eggs. Founder mice were bred to C57BL/6 mice, and backcrossed to the same for 11 generations.

Control Information

  Control
   Noncarrier
   000664 C57BL/6J
 
  Considerations for Choosing Controls

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009655   C57BL/6J-Tg(Dcx-DsRed)14Qlu/J
007857   C57BL/6J-Tg(Eno2-YFP/Cox8a)YRwb/J
007860   C57BL/6J-Tg(Eno2-YFP/Cox8a)ZRwb/J
007567   C57BL/6J-Tg(Itgax-cre,-EGFP)4097Ach/J
009593   C57BL/6J-Tg(Pomc-EGFP)1Low/J
003927   C57BL/6J-Tg(Sry-EGFP)92Ei/EiJ
008234   CB6-Tg(CAG-EGFP/CETN2)3-4Jgg/J
007677   CB6-Tg(Gad1-EGFP)G42Zjh/J
007898   CBy.Cg-Tg(Gt(ROSA)26Sor-EGFP)I1Able/J
007075   CByJ.B6-Tg(CAG-EGFP)1Osb/J
007076   CByJ.B6-Tg(UBC-GFP)30Scha/J
010548   D1.FVB(Cg)-Tg(CAG-luc,-GFP)L2G85Chco/FathJ
008450   FVB-Tg(CAG-luc,-GFP)L2G85Chco/J
003718   FVB-Tg(GadGFP)45704Swn/J
010947   FVB-Tg(Gstm5-EGFP)1Ilis/J
005515   FVB-Tg(ITGAM-DTR/EGFP)34Lan/J
010588   FVB-Tg(Myh6/NFAT-luc)1Jmol/J
006421   FVB-Tg(Pomc1-hrGFP)1Lowl/J
005688   FVB-Tg(Rag2-EGFP)1Mnz/J
005125   FVB.129S6(B6)-Gt(ROSA)26Sortm1(Luc)Kael/J
006206   FVB.129S6-Gt(ROSA)26Sortm2(HIF1A/luc)Kael/J
012429   FVB.Cg-Gt(ROSA)26Sortm1(CAG-lacZ,-EGFP)Glh/J
003516   FVB.Cg-Tg(CAG-EGFP)B5Nagy/J
016573   FVB.Cg-Tg(SMN2)89Ahmb Smn1tm1Msd Tg(S100B-EGFP)1Wjt Tg(SMN2*delta7)4299Ahmb/J
007483   FVB.Cg-Tg(Tyr)3412ARpw Tg(Sry-EGFP)92Ei/EiJ
008200   FVB/N-Tg(CAG-EGFP,-ALPP)2.6Ggc/J
009354   FVB/N-Tg(Dazl-EGFP)10Rarp/J
003257   FVB/N-Tg(GFAPGFP)14Mes/J
007800   FVB/N-Tg(Ins1-luc)VUPwrs/J
012370   FVB/NJ-Tg(Hspa1a-luc,-EGFP)2Chco/J
009618   NOD.129(B6)-Il12btm1Lky/JbsJ
013116   NOD.B6-Tg(Ins2-luc/EGFP/TK)300Kauf/J
013233   NOD.B6-Tg(Itgax-cre,-EGFP)4097Ach/J
006698   NOD.Cg-Il4tm1Lky/JbsJ
008173   NOD.Cg-Tg(Ins1-EGFP)1Hara/QtngJ
009422   NOD.Cg-Tg(Itgax-Venus)1Mnz/QtngJ
005076   NOD.Cg-Tg(tetO-EGFP/FADD)1Doi/DoiJ
010542   NOD.FVB-Tg(CAG-luc,-GFP)L2G85Chco/FathJ
008547   NOD.FVB-Tg(ITGAM-DTR/EGFP)34Lan/JdkJ
008549   NOD.FVB-Tg(Itgax-DTR/EGFP)57Lan/JdkJ
005082   NOD/ShiLt-Tg(ACTB-Ica1/EGFP)18Mdos/MdosJ
005328   NOD/ShiLt-Tg(Cd4-DsRed)4Lt/J
005334   NOD/ShiLt-Tg(Cd4-EGFP)1Lt/J
008694   NOD/ShiLt-Tg(Foxp3-EGFP/cre)1cJbs/J
005282   NOD/ShiLtJ-Tg(Ins1-EGFP/GH1)14Hara/HaraJ
012881   STOCK Ascl1tm1Reed/J
008666   STOCK Fmn1tm1Made/J
013731   STOCK Gt(ROSA)26Sortm1(CAG-Brainbow2.1)Cle/J
006331   STOCK Gt(ROSA)26Sortm1(DTA)Jpmb/J
005130   STOCK Gt(ROSA)26Sortm1(Smo/EYFP)Amc/J
005572   STOCK Gt(ROSA)26Sortm1(rtTA,EGFP)Nagy/J
017922   STOCK Gt(ROSA)26Sortm10(ACTB-tdTomato)Luo/J
018903   STOCK Gt(ROSA)26Sortm2(EGFP/cre)Alj/J
007576   STOCK Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/J
024107   STOCK Gt(ROSA)26Sortm5(ACTB-tTA)Luo Igs7tm93.1(tetO-GCaMP6f)Hze/HzeJ
017912   STOCK Gt(ROSA)26Sortm6(ACTB-EGFP*,-tdTomato)Luo/J
017921   STOCK Gt(ROSA)26Sortm7(ACTB-EGFP*)Luo/J
017909   STOCK Gt(ROSA)26Sortm8(ACTB-EGFP*,-tTA2)Luo/J
008876   STOCK Hprttm11(Ple176-EGFP/cre)Ems/Mmjax
009349   STOCK Hprttm31(Ple67-EGFP)Ems/Mmjax
009594   STOCK Hprttm32(Ple112-EGFP)Ems/Mmjax
022976   STOCK Igs2tm1(ACTB-EGFP,-tdTomato)Zng/J
022977   STOCK Igs2tm2(ACTB-tdTomato,-EGFP)Zng/J
024108   STOCK Igs7tm93.1(tetO-GCaMP6f)Hze Tg(Camk2a-tTA)1Mmay/J
013749   STOCK Iis2tm1(ACTB-EGFP,-tdTomato)Luo/J
013751   STOCK Iis2tm2(ACTB-tdTomato,-EGFP)Luo/J
017932   STOCK Iis3tm1.1(ACTB-EGFP*)Luo/J
017923   STOCK Iis3tm2.1(ACTB-EGFP*,-tdTomato)Luo/J
021458   STOCK Iis5tm1(ACTB-tdTomato,-EGFP)Luo/J
021457   STOCK Iis5tm2.1(ACTB-EGFP,-tdTomato)Luo/J
021461   STOCK Iis6tm1.1(ACTB-tdTomato,-EFGP)Luo/J
021460   STOCK Iis6tm2.1(ACTB-EFGP,-tdTomato)Luo/J
004808   STOCK Mapttm1(EGFP)Klt Tg(MAPT)8cPdav/J
004779   STOCK Mapttm1(EGFP)Klt/J
005692   STOCK Nphs1tm1Rkl/J
006741   STOCK Olfr160tm1(Olfr151)Mom Tg(Olfr151,taulacZ)BMom/MomJ
006678   STOCK Olfr160tm6Mom/MomJ
006669   STOCK Olfr17tm7Mom/MomJ
009061   STOCK Osr1tm1(EGFP/cre/ERT2)Amc/J
007879   STOCK Stx1atm2Sud/J
014581   STOCK Trpm8tm1Apat/J
010911   STOCK Wt1tm1(EGFP/cre)Wtp/J
005438   STOCK Tg(CAG-Bgeo,-DsRed*MST)1Nagy/J
006850   STOCK Tg(CAG-Bgeo,-NOTCH1,-EGFP)1Lbe/J
006876   STOCK Tg(CAG-Bgeo,-TEL/AML1,-EGFP)A6Lbe/J
003920   STOCK Tg(CAG-Bgeo/GFP)21Lbe/J
005441   STOCK Tg(CAG-DsRed*MST)1Nagy/J
003773   STOCK Tg(CAG-ECFP)CK6Nagy/J
003115   STOCK Tg(CAG-EGFP)B5Nagy/J
003116   STOCK Tg(CAG-EGFP)D4Nagy/J
011106   STOCK Tg(CAG-GFP*)1Hadj/J
013754   STOCK Tg(CAG-KikGR)75Hadj/J
011107   STOCK Tg(CAG-Venus)1Hadj/J
005645   STOCK Tg(CAG-mRFP1)1F1Hadj/J
005105   STOCK Tg(Chx10-EGFP/cre,-ALPP)2Clc/J
018322   STOCK Tg(Cp-EGFP)25Gaia/ReyaJ
008241   STOCK Tg(Cspg4-DsRed.T1)1Akik/J
006334   STOCK Tg(Gad1-EGFP)94Agmo/J
006340   STOCK Tg(Gad1-EGFP)98Agmo/J
007896   STOCK Tg(Gt(ROSA)26Sor-EGFP)I1Able/J
016252   STOCK Tg(Hoxb7-Venus*)17Cos/J
006784   STOCK Tg(Ins1-Cerulean)24Hara/J
006866   STOCK Tg(Ins1-DsRed*T4)32Hara/J
016921   STOCK Tg(Myh2-DsRed2)1Jrs/J
012477   STOCK Tg(Myh6*/tetO-GCaMP2)1Mik/J
016922   STOCK Tg(Myh7-CFP)1Jrs/J
008579   STOCK Tg(PSCA-EGFP)1Witt/J
012452   STOCK Tg(Rr5-GFP/cre)1Sapc/J
006570   STOCK Tg(SMN2)89Ahmb Smn1tm1Msd Tg(Hlxb9-GFP)1Tmj/J
009606   STOCK Tg(Six2-EGFP/cre)1Amc/J
003658   STOCK Tg(TIE2GFP)287Sato/J
013162   STOCK Tg(Thy1-Clomeleon)12Gjau/J
013163   STOCK Tg(Thy1-Clomeleon)13Gjau/J
007788   STOCK Tg(Thy1-EGFP)MJrs/J
012708   STOCK Tg(Thy1-cre/ERT2,-EYFP)HGfng/PyngJ
011108   STOCK Tg(Ttr-RFP)1Hadj/J
016981   STOCK Tg(Uchl1-HIST2H2BE/mCherry/EGFP*)FSout/J
006129   STOCK Tg(Zp3-EGFP)1Dean/J
003274   STOCK Tg(tetNZL)2Bjd/J
005104   STOCK Tg(tetO-HIST1H2BJ/GFP)47Efu/J
005699   STOCK Tg(tetO-Ipf1,EGFP)956.6Macd/J
017918   STOCK Tg(tetO-MAML1*/EGFP)2Akar/J
012345   STOCK Tg(tetO-tdTomato,-Syp/EGFP*)1.1Luo/J
View Fluorescent Protein Strains     (382 strains)

Strains carrying other alleles of GFP
006053   129-Gt(ROSA)26Sortm1(CAG-EGFP)Luo/J
006067   129-Gt(ROSA)26Sortm2(CAG-Dsred2/EGFP)Luo/J
006041   129-Gt(ROSA)26Sortm3(CAG-EGFP/Dsred2)Luo/J
016925   129;B6-Del(10Grin3b-Tmem259)1Zang Tg(Prnp-C19ORF6,-GFP)6Zhang/J
016251   129S.Cg-Tg(Hoxb7-EGFP)33Cos/J
003960   129S6-Tg(Prnp-GFP/cre)1Blw/J
017458   B6(C)-Tg(UAS-EGFP,-SOD1*G37R)135Gsn/J
017460   B6(C)-Tg(UAS-EGFP,-SOD1*G37R)677Gsn/J
008242   B6(Cg)-Gt(ROSA)26Sortm4(Ikbkb)Rsky/J
021011   B6(D2)-Tg(CAG-Brainbow1.0)2Eggn/J
021012   B6(D2)-Tg(CAG-Brainbow1.0)3Eggn/J
021469   B6(D2)-Tg(CAG-GFP,-Uprt)985Cdoe/J
016958   B6.129(Cg)-Foxp3tm3(DTR/GFP)Ayr/J
007676   B6.129(Cg)-Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/J
004178   B6.129(Cg)-Tg(CAG-Bgeo/GFP)21Lbe/J
018979   B6.129(Cg)-Tg(CAG-EGFP)D4Nagy/KnwJ
010635   B6.129(FVB)-Alcamtm1Jawe/J
006071   B6.129-Gt(ROSA)26Sortm1(CAG-EGFP)Luo/J
008606   B6.129-Gt(ROSA)26Sortm1Joe/J
006080   B6.129-Gt(ROSA)26Sortm2(CAG-Dsred2/EGFP)Luo/J
006075   B6.129-Gt(ROSA)26Sortm3(CAG-EGFP/Dsred2)Luo/J
011036   B6.129-Hoxa11tm1Dmwe/J
025880   B6.129-Tg(EEF1A1-SHC1*)1Ravi/J
008451   B6.129P(Cg)-Ptprca Cx3cr1tm1Litt/LittJ
005582   B6.129P-Cx3cr1tm1Litt/J
008710   B6.129P2(129S4)-Hprttm10(Ple162-EGFP/cre)Ems/Mmjax
008877   B6.129P2(129S4)-Hprttm12(Ple177-EGFP/cre)Ems/Mmjax
009114   B6.129P2(129S4)-Hprttm14(Ple103-EGFP/cre)Ems/Mmjax
008709   B6.129P2(129S4)-Hprttm9(Ple178-EGFP/cre)Ems/Mmjax
009113   B6.129P2(Cg)-Hprttm13(Ple54-EGFP)Ems/Mmjax
009115   B6.129P2(Cg)-Hprttm15(Ple111-EGFP)Ems/Mmjax
009118   B6.129P2(Cg)-Hprttm18(Ple90-EGFP)Ems/Mmjax
009353   B6.129P2(Cg)-Hprttm20(Ple53-EGFP)Ems/Mmjax
009596   B6.129P2(Cg)-Hprttm33(Ple183-EGFP)Ems/Mmjax
010770   B6.129P2(Cg)-Hprttm34(Ple186-EGFP)Ems/Mmjax
008706   B6.129P2(Cg)-Hprttm4(Ple88-EGFP)Ems/Mmjax
010789   B6.129P2(Cg)-Hprttm54(Ple233-EGFP)Ems/Mmjax
008707   B6.129P2(Cg)-Hprttm7(Ple185-EGFP)Ems/Mmjax
008708   B6.129P2(Cg)-Hprttm8(Ple151-EGFP)Ems/Mmjax
007766   B6.129P2(Cg)-Olfr160tm6Mom/MomJ
007572   B6.129P2(Cg)-Rorctm2Litt/J
005693   B6.129P2-Cxcr6tm1Litt/J
008875   B6.129P2-Lgr5tm1(cre/ERT2)Cle/J
016934   B6.129P2-Lgr6tm2.1(cre/ERT2)Cle/J
021794   B6.129S1(Cg)-Ascl3tm1.1(EGFP/cre)Ovi/J
009380   B6.129S1-Irf4tm1Rdf/J
021930   B6.129S1-Tg(CAG-EGFP)S1C2Tpo/KnwPeaJ
022510   B6.129S4-Gpr88tm1.1(cre/GFP)Rpa/J
007669   B6.129S4-Pdgfratm11(EGFP)Sor/J
013061   B6.129S6-Ccr6tm1(EGFP)Irw/J
008379   B6.129S6-Il10tm1Flv/J
012644   B6.129S7-Pcdhgtm2Xzw/J
008466   B6.129X1(Cg)-Shhtm6Amc/J
009081   B6.129X1-Id1tm1Xhsu/J
006772   B6.Cg-Foxp3tm2Tch/J
005670   B6.Cg-Gt(ROSA)26Sortm1(rtTA,EGFP)Nagy/J
007906   B6.Cg-Gt(ROSA)26Sortm6(CAG-ZsGreen1)Hze/J
005491   B6.Cg-Mapttm1(EGFP)Klt Tg(MAPT)8cPdav/J
022486   B6.Cg-Ptprca Tg(UBC-PA-GFP)1Mnz/J
025855   B6.Cg-Ptprca Lag3tm1Doi Tg(CAG-luc,-GFP)L2G85Chco Thy1a/J
013115   B6.Cg-Rag1tm1Mom Tg(UBC-GFP)30Scha/J
005622   B6.Cg-Shhtm1(EGFP/cre)Cjt/J
007484   B6.Cg-Tyrc-2J Tg(Tyr)3412ARpw Tg(Sry-EGFP)92Ei/EiJ
008705   B6.Cg-Tg(CAG-DsRed,-EGFP)5Gae/J
007575   B6.Cg-Tg(CAG-Ngb,-EGFP)1Dgrn/J
008111   B6.Cg-Tg(CAG-Ub*G76V/GFP)1Dant/J
008112   B6.Cg-Tg(CAG-Ub*G76V/GFP)2Dant/J
022148   B6.Cg-Tg(CSNK1D*,-EGFP)827Yfu/J
022149   B6.Cg-Tg(CSNK1D,-EGFP)432Yfu/J
023404   B6.Cg-Tg(CSNK1D,-EGFP)433Yfu/J
022787   B6.Cg-Tg(Chst4-EGFP)23Nrud/J
013134   B6.Cg-Tg(Col1a1*2.3-GFP)1Rowe/J
017466   B6.Cg-Tg(Col1a1*3.6-Topaz)2Rowe/J
018306   B6.Cg-Tg(Fos-tTA,Fos-EGFP*)1Mmay/J
014135   B6.Cg-Tg(Fos/EGFP)1-3Brth/J
007673   B6.Cg-Tg(Gad1-EGFP)3Gfng/J
010835   B6.Cg-Tg(Gfap-EGFP)3739Sart/J
007897   B6.Cg-Tg(Gt(ROSA)26Sor-EGFP)I1Able/J
006069   B6.Cg-Tg(HIST1H2BB/EGFP)1Pa/J
005029   B6.Cg-Tg(Hlxb9-GFP)1Tmj/J
024808   B6.Cg-Tg(Inpp5d-EGFP)DLrr/CprJ
006864   B6.Cg-Tg(Ins1-EGFP)1Hara/J
005244   B6.Cg-Tg(Krt1-15-EGFP)2Cot/J
012643   B6.Cg-Tg(Ly6a-EGFP)G5Dzk/J
008323   B6.Cg-Tg(Mc4r-MAPT/Sapphire)21Rck/J
007742   B6.Cg-Tg(Myh11-cre,-EGFP)2Mik/J
008321   B6.Cg-Tg(Npy-MAPT/Sapphire)1Rck/J
021232   B6.Cg-Tg(Nrl-EGFP)1Asw/J
008324   B6.Cg-Tg(Pmch-MAPT/CFP)1Rck/J
008322   B6.Cg-Tg(Pomc-MAPT/Topaz)1Rck/J
007902   B6.Cg-Tg(RP23-268L19-EGFP)2Mik/J
022086   B6.Cg-Tg(RP24-131B16/EGFP)13Ghan/J
019494   B6.Cg-Tg(RP24-131B16/EGFP)37Ghan/J
007894   B6.Cg-Tg(Rgs4-EGFP)4Lvt/J
021614   B6.Cg-Tg(S100A8-cre,-EGFP)1Ilw/J
012893   B6.Cg-Tg(S100a4-EGFP)M1Egn/YunkJ
006361   B6.Cg-Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/J
016998   B6.Cg-Tg(TetO-Axin1,EGFP)TA6Cos/J
007921   B6.Cg-Tg(Thy1-Brainbow2.1)RLich/J
007919   B6.Cg-Tg(Thy1-EGFP)OJrs/GfngJ
021069   B6.Cg-Tg(Thy1-PA-GFP)5Rmpl/J
021070   B6.Cg-Tg(Thy1-PA-GFP)6Rmpl/J
015805   B6.Cg-Tg(UBC-GFP,-TVA)1Clc/J
015806   B6.Cg-Tg(UBC-GFP,-TVA)2Clc/J
015807   B6.Cg-Tg(UBC-GFP,-TVA)3Clc/J
024688   B6.FVB(129S)-Tg(Pax6-GFP/cre)1Rilm/J
025854   B6.FVB-Ptprca Tg(CAG-luc,-GFP)L2G85Chco Thy1a/J
008226   B6.FVB-Tg(CAG-EGFP,-ALPP)2.6Ggc/J
018056   B6.FVB-Tg(CAG-boNT/B,-EGFP)U75-56Fwp/J
018055   B6.FVB-Tg(H2-K-S100a9,GFP)1Gabr/J
006000   B6.FVB-Tg(ITGAM-DTR/EGFP)34Lan/J
004509   B6.FVB-Tg(Itgax-DTR/EGFP)57Lan/J
006417   B6.FVB-Tg(Npy-hrGFP)1Lowl/J
024033   B6.FVB-Tg(Shank3-EGFP)1Hzo/J
005738   B6.FVB-Tg(tetO-EGFP,-Tgfbr2)8Mcle/J
008126   B6.NOD-Tg(Cd4-EGFP)1Lt/J
023161   B6129S-Tg(Foxp3-EGFP/cre)1aJbs/J
024179   B6;129-Gt(ROSA)26Sortm1(Actb-T,-GFP)Dalco/J
008516   B6;129-Gt(ROSA)26Sortm1Joe/J
004077   B6;129-Gt(ROSA)26Sortm2Sho/J
009600   B6;129-Six2tm3(EGFP/cre/ERT2)Amc/J
008678   B6;129-Ubbtm1Rrk/J
010988   B6;129P-Cyp11a1tm1(GFP/cre)Pzg/J
010985   B6;129P-Klf3tm1(cre/ERT2)Pzg/J
015854   B6;129P2-Foxl2tm1(GFP/cre/ERT2)Pzg/J
008769   B6;129P2-Gpr15tm1.1Litt/J
012601   B6;129P2-Lyve1tm1.1(EGFP/cre)Cys/J
021162   B6;129P2-Mapttm2Arbr/J
006717   B6;129P2-Olfr124tm1Mom/MomJ
006665   B6;129P2-Olfr151tm13(rI7)Mom/MomJ
006666   B6;129P2-Olfr151tm24(Olfr2)Mom/MomJ
006676   B6;129P2-Olfr151tm26Mom/MomJ
006734   B6;129P2-Olfr151tm35(Adrb2)Mom/MomJ
006714   B6;129P2-Olfr160tm11(Olfr545)Mom/MomJ
006649   B6;129P2-Olfr17tm5(Olfr6)Mom/MomJ
006712   B6;129P2-Olfr545tm1Mom/MomJ
006715   B6;129P2-Olfr545tm3(Olfr160)Mom/MomJ
004946   B6;129P2-Omptm2(spH)Mom/J
006667   B6;129P2-Omptm3Mom/MomJ
006728   B6;129P2-Vmn2r26tm2Mom/MomJ
012735   B6;129S-Gt(ROSA)26Sortm35.1(CAG-aop3/GFP)Hze/J
010987   B6;129S-Sox18tm1(GFP/cre/ERT2)Pzg/J
017592   B6;129S-Sox2tm2Hoch/J
004858   B6;129S1-Tshrtm1Rmar/J
007843   B6;129S4-Efnb2tm2Sor/J
012463   B6;129S4-Foxd1tm1(GFP/cre)Amc/J
012464   B6;129S4-Foxd1tm2(GFP/cre/ERT2)Amc/J
016836   B6;129S4-Gt(ROSA)26Sortm1(rtTA*M2)Jae Col1a1tm7(tetO-HIST1H2BJ/GFP)Jae/J
008214   B6;129S4-Pou5f1tm2Jae/J
008078   B6;129S4-Tcf3tm5Zhu/J
017495   B6;129S7-Crim1tm1(GFP/cre/ERT2)Pzg/J
012436   B6;129S7-Tg(CAG-lacZ,-BMPR1A*,-EGFP)1Mis/Mmjax
008605   B6;C3-Tg(CAG-DsRed,-EGFP)5Gae/J
008080   B6;C3-Tg(CAG-SAC/EGFP)35Rang/J
010827   B6;C3-Tg(FOXJ1-EGFP)85Leo/J
010930   B6;CB-Tg(Pbsn-Hpn,-GFP)DVv/J
010704   B6;CBA-Tg(ATP6V1B1-EGFP)1Rnel/Mmjax
004966   B6;CBA-Tg(Acrv1-EGFP)2727Redd/J
025820   B6;CBA-Tg(CRH-MAPT/Topaz)1Rck/J
021588   B6;CBA-Tg(Gast-EGFP)1Tcw/J
007986   B6;CBA-Tg(H*/Olfr16-GFP)11Mom/MomJ
007987   B6;CBA-Tg(H*/Olfr16-GFP)25Mom/MomJ
007979   B6;CBA-Tg(H/Olfr16-GFP)3Mom/MomJ
007980   B6;CBA-Tg(H/Olfr16-GFP)4Mom/MomJ
007981   B6;CBA-Tg(H/Olfr16-GFP)6Mom/MomJ
007984   B6;CBA-Tg(H/Olfr16-taumCherry,-tauGFP)11Mom/MomJ
007985   B6;CBA-Tg(H/Olfr16-taumCherry,-tauGFP)13Mom/MomJ
007982   B6;CBA-Tg(H/Olfr16-taumRFP,-tauGFP)8Mom/MomJ
007983   B6;CBA-Tg(H/Olfr16-taumRFP,-tauGFP)9Mom/MomJ
007978   B6;CBA-Tg(Hf/Olfr16-GFP)47Mom/MomJ
007977   B6;CBA-Tg(Hf/Olfr16-GFP)7Mom/MomJ
004654   B6;CBA-Tg(Pou5f1-EGFP)2Mnn/J
011070   B6;CBA-Tg(Thy1-EGFP)SJrs/NdivJ
014651   B6;CBA-Tg(Thy1-spH)21Vnmu/J
015814   B6;CBA-Tg(Thy1-spH)64Vnmu/FrkJ
017494   B6;D-Tg(Tshz3-GFP/cre)43Amc/J
025122   B6;D2-Tg(RP24-330G11-EGFP)1Mik/J
005621   B6;D2-Tg(S100B-EGFP)1Wjt/J
008344   B6;DBA-Tg(Fos-tTA,Fos-EGFP*)1Mmay Tg(tetO-lacZ,tTA*)1Mmay/J
014160   B6;DBA-Tg(S100b-EGFP/cre/ERT2)22Amc/J
014159   B6;DBA-Tg(Tmem100-EGFP/cre/ERT2)30Amc/J
015855   B6;DBA-Tg(Upk3a-GFP/cre/ERT2)26Amc/J
009159   B6;FVB-Tg(Cnp-EGFP/Rpl10a)JD368Htz/J
021187   B6;FVB-Tg(Pbsn-rtTA*M2)42Xy/J
004690   B6;FVB-Tg(Pcp2-EGFP)2Yuza/J
006147   B6;FVB-Tg(Sfpi1,-EGFP)7Dgt/J
019381   B6;FVB-Tg(Zfp423-EGFP)7Brsp/J
021022   B6;SJL-Tg(AMELX-EGFP/RHOA*T19N)13Gibs/Mmjax
006043   B6;SJL-Tg(Oxt/EGFP)AI03Wsy/J
021078   B6N.129S1-Mrgprb4tm4.1(flpo)And/J
019013   B6N.129S6(Cg)-Gt(ROSA)26Sortm2(EGFP/cre)Alj/J
018974   B6N.B6-Tg(Nr4a1-EGFP/cre)820Khog/J
018549   B6N.Cg-Tg(Csf1r-EGFP)1Hume/J
020650   B6N.Cg-Tg(Trpm8-EGFP)1Dmck/J
018913   B6N.Cg-Tg(tetO-GFP,-lacZ)G3Rsp/J
007732   B6SJL-Tg(Dazl-hrGFP)4Gar/J
004190   C.129-Il4tm1Lky/J
005700   C.129P2-Cxcr6tm1Litt/J
011010   C.B6-Tg(Foxp3-DTR/EGFP)23.2Spar/Mmjax
006769   C.Cg-Foxp3tm2Tch/J
010545   C.FVB-Tg(CAG-luc,-GFP)L2G85Chco/FathJ
004512   C.FVB-Tg(Itgax-DTR/EGFP)57Lan/J
008591   C57BL/6-Ackr3tm1Litt/J
023520   C57BL/6-Bcrtm1(BCR/ABL)Tsr/J
012343   C57BL/6-Gt(ROSA)26Sortm7(Pik3ca*,EGFP)Rsky/J
012361   C57BL/6-Gt(ROSA)26Sortm9(Rac1*,EGFP)Rsky/J
010724   C57BL/6-Trim21tm1Hm/J
017469   C57BL/6-Tg(BGLAP-Topaz)1Rowe/J
003291   C57BL/6-Tg(CAG-EGFP)1Osb/J
005070   C57BL/6-Tg(Csf1r-EGFP-NGFR/FKBP1A/TNFRSF6)2Bck/J
017467   C57BL/6-Tg(Dmp1-Topaz)1Ikal/J
011003   C57BL/6-Tg(Foxp3-DTR/EGFP)23.2Spar/Mmjax
023800   C57BL/6-Tg(Foxp3-GFP)90Pkraj/J
012943   C57BL/6-Tg(Ins2-luc/EGFP/TK)300Kauf/J
016617   C57BL/6-Tg(Nr4a1-EGFP/cre)820Khog/J
012890   C57BL/6-Tg(Scgb1a1-Il17f,GFP)1Cdon/J
007265   C57BL/6-Tg(Sry-EGFP)92Ei Chr YAKR/J/EiJ
007264   C57BL/6-Tg(Sry-EGFP)92Ei Tg(Sry)4Ei Chr YPOS/EiJ
004353   C57BL/6-Tg(UBC-GFP)30Scha/J
022476   C57BL/6-Tg(Uchl1-EGFP)G1Phoz/J
005706   C57BL/6-Tg(tetO-CDK5R1/GFP)337Lht/J
007567   C57BL/6J-Tg(Itgax-cre,-EGFP)4097Ach/J
018895   C57BL/6J-Tg(Krt6,-cre,-Cerulean)1Grsr/Grsr
018896   C57BL/6J-Tg(Krt6,-cre,-Cerulean)2Grsr/Grsr
018898   C57BL/6J-Tg(Krt6,-cre,-Cerulean)4Grsr/Grsr
018899   C57BL/6J-Tg(Krt6,-cre,-Cerulean)5Grsr/Grsr
009593   C57BL/6J-Tg(Pomc-EGFP)1Low/J
003927   C57BL/6J-Tg(Sry-EGFP)92Ei/EiJ
019363   C57BL/6J-Tg(Trp63,-cre,-Cerulean)10Grsr/Grsr
018792   C57BL/6J-Tg(Trp63,-cre,-Cerulean)4Grsr/GrsrJ
024898   C57BL/6J-Tg(tetO-EGFP/Rpl10a)5aReij/J
018151   C57BL/6N-Krt17tm1(cre,Cerulean)Murr/GrsrJ
024753   C57BL/6N-Tg(Ddx25*-EGFP)1Mld/J
024752   C57BL/6N-Tg(Ddx25-EGFP)1Mld/J
008234   CB6-Tg(CAG-EGFP/CETN2)3-4Jgg/J
007677   CB6-Tg(Gad1-EGFP)G42Zjh/J
007898   CBy.Cg-Tg(Gt(ROSA)26Sor-EGFP)I1Able/J
007075   CByJ.B6-Tg(CAG-EGFP)1Osb/J
007076   CByJ.B6-Tg(UBC-GFP)30Scha/J
010548   D1.FVB(Cg)-Tg(CAG-luc,-GFP)L2G85Chco/FathJ
008450   FVB-Tg(CAG-luc,-GFP)L2G85Chco/J
003718   FVB-Tg(GadGFP)45704Swn/J
010947   FVB-Tg(Gstm5-EGFP)1Ilis/J
005515   FVB-Tg(ITGAM-DTR/EGFP)34Lan/J
017484   FVB-Tg(JPH3-GFP,-JPH3*)GXwy/J
006421   FVB-Tg(Pomc1-hrGFP)1Lowl/J
005688   FVB-Tg(Rag2-EGFP)1Mnz/J
024636   FVB.B6-Tg(CAG-cat,-EGFP)1Rbns/KrnzJ
012429   FVB.Cg-Gt(ROSA)26Sortm1(CAG-lacZ,-EGFP)Glh/J
003516   FVB.Cg-Tg(CAG-EGFP)B5Nagy/J
022735   FVB.Cg-Tg(Cspg4-EGFP*)HDbe/J
016573   FVB.Cg-Tg(SMN2)89Ahmb Smn1tm1Msd Tg(S100B-EGFP)1Wjt Tg(SMN2*delta7)4299Ahmb/J
007483   FVB.Cg-Tg(Tyr)3412ARpw Tg(Sry-EGFP)92Ei/EiJ
008200   FVB/N-Tg(CAG-EGFP,-ALPP)2.6Ggc/J
018393   FVB/N-Tg(CAG-EGFP,TGFB1*)C8Kul/J
026105   FVB/N-Tg(Cnp-EGFP*)10Qrlu/J
009354   FVB/N-Tg(Dazl-EGFP)10Rarp/J
025062   FVB/N-Tg(Figla-EGFP,-icre)ZP3Dean/Mmjax
018548   FVB/N-Tg(GFAP-Cadm1/EGFP)42Oje/J
003257   FVB/N-Tg(GFAPGFP)14Mes/J
025097   NOD.129X1(Cg)-Foxp3tm2Tch/DvsJ
013116   NOD.B6-Tg(Ins2-luc/EGFP/TK)300Kauf/J
013233   NOD.B6-Tg(Itgax-cre,-EGFP)4097Ach/J
006698   NOD.Cg-Il4tm1Lky/JbsJ
021937   NOD.Cg-Prkdcscid Il2rgtm1Wjl Tg(CAG-EGFP)1Osb/SzJ
017619   NOD.Cg-Prkdcscid Tg(CAG-EGFP)1Osb/KupwJ
008173   NOD.Cg-Tg(Ins1-EGFP)1Hara/QtngJ
005076   NOD.Cg-Tg(tetO-EGFP/FADD)1Doi/DoiJ
010542   NOD.FVB-Tg(CAG-luc,-GFP)L2G85Chco/FathJ
008547   NOD.FVB-Tg(ITGAM-DTR/EGFP)34Lan/JdkJ
008549   NOD.FVB-Tg(Itgax-DTR/EGFP)57Lan/JdkJ
005082   NOD/ShiLt-Tg(ACTB-Ica1/EGFP)18Mdos/MdosJ
005334   NOD/ShiLt-Tg(Cd4-EGFP)1Lt/J
008694   NOD/ShiLt-Tg(Foxp3-EGFP/cre)1cJbs/J
005282   NOD/ShiLtJ-Tg(Ins1-EGFP/GH1)14Hara/HaraJ
012881   STOCK Ascl1tm1Reed/J
008666   STOCK Fmn1tm1Made/J
016961   STOCK Foxp3tm9(EGFP/cre/ERT2)Ayr/J
006331   STOCK Gt(ROSA)26Sortm1(DTA)Jpmb/J
005572   STOCK Gt(ROSA)26Sortm1(rtTA,EGFP)Nagy/J
017596   STOCK Gt(ROSA)26Sortm1.1(rtTA,EGFP)Nagy Tg(SMN2)89Ahmb Smn1tm1Msd Tg(SMN2*delta7)4299Ahmb Tg(tetO-SMN2,-luc)#aAhmb/J
017597   STOCK Gt(ROSA)26Sortm1.1(rtTA,EGFP)Nagy Tg(SMN2)89Ahmb Smn1tm1Msd Tg(SMN2*delta7)4299Ahmb Tg(tetO-SMN2,-luc)#bAhmb/J
025671   STOCK Gt(ROSA)26Sortm1.1(rtTA,EGFP)Nagy Tg(tetO-Fgf10)1Jaw/SpdlJ
024746   STOCK Gt(ROSA)26Sortm1.1(rtTA,EGFP)Nagy Hprttm1(tetO-Dkk1)Spdl Tg(TCF/Lef1-lacZ)34Efu/J
018903   STOCK Gt(ROSA)26Sortm2(EGFP/cre)Alj/J
007576   STOCK Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/J
008876   STOCK Hprttm11(Ple176-EGFP/cre)Ems/Mmjax
009349   STOCK Hprttm31(Ple67-EGFP)Ems/Mmjax
009594   STOCK Hprttm32(Ple112-EGFP)Ems/Mmjax
017530   STOCK Igs2tm2(ACTB-tdTomato,-EGFP)Luo Trp53tm1Tyj Nf1tm1Par/J
013749   STOCK Iis2tm1(ACTB-EGFP,-tdTomato)Luo/J
013751   STOCK Iis2tm2(ACTB-tdTomato,-EGFP)Luo/J
017932   STOCK Iis3tm1.1(ACTB-EGFP*)Luo/J
017923   STOCK Iis3tm2.1(ACTB-EGFP*,-tdTomato)Luo/J
017701   STOCK Kiss1tm1.1(cre/EGFP)Stei/J
004808   STOCK Mapttm1(EGFP)Klt Tg(MAPT)8cPdav/J
004779   STOCK Mapttm1(EGFP)Klt/J
005692   STOCK Nphs1tm1Rkl/J
006702   STOCK Ntstm1Mom/MomJ
006622   STOCK Olfr151tm10Mom/MomJ
006646   STOCK Olfr151tm11(Olfr160)Mom/MomJ
006692   STOCK Olfr151tm16(Olfr160/Olfr161)Mom/MomJ
006627   STOCK Olfr151tm4Mom/MomJ
006626   STOCK Olfr151tm6Mom/MomJ
006625   STOCK Olfr151tm7Mom/MomJ
006624   STOCK Olfr151tm8Mom/MomJ
006623   STOCK Olfr151tm9Mom/MomJ
006740   STOCK Olfr160tm1(Olfr151)Mom Tg(Olfr151,taulacZ)AMom/MomJ
006741   STOCK Olfr160tm1(Olfr151)Mom Tg(Olfr151,taulacZ)BMom/MomJ
006647   STOCK Olfr160tm1(Olfr151)Mom/MomJ
006636   STOCK Olfr160tm5(Cnga2)Mom/MomJ
006678   STOCK Olfr160tm6Mom/MomJ
006650   STOCK Olfr17tm6(Olfr713)Mom/MomJ
006669   STOCK Olfr17tm7Mom/MomJ
009061   STOCK Osr1tm1(EGFP/cre/ERT2)Amc/J
022757   STOCK Prg4tm1(GFP/cre/ERT2)Abl/J
006770   STOCK Rag1tm1Mom Tg(TIE2GFP)287Sato/J
006633   STOCK Vmn1r49tm3Mom/MomJ
010911   STOCK Wt1tm1(EGFP/cre)Wtp/J
017472   STOCK Tg(Acp5-CFP,Ibsp-YFP,Dmp1-RFP)1Pmay/J
006850   STOCK Tg(CAG-Bgeo,-NOTCH1,-EGFP)1Lbe/J
006876   STOCK Tg(CAG-Bgeo,-TEL/AML1,-EGFP)A6Lbe/J
003920   STOCK Tg(CAG-Bgeo/GFP)21Lbe/J
003115   STOCK Tg(CAG-EGFP)B5Nagy/J
003116   STOCK Tg(CAG-EGFP)D4Nagy/J
017919   STOCK Tg(CAG-EGFP,-dsRed2/RNAi:Tardbp)6Zxu/J
011106   STOCK Tg(CAG-GFP*)1Hadj/J
013753   STOCK Tg(CAG-KikGR)33Hadj/J
013754   STOCK Tg(CAG-KikGR)75Hadj/J
019082   STOCK Tg(CMV-GFP,-BBS4)4T25Vcs/J
005105   STOCK Tg(Chx10-EGFP/cre,-ALPP)2Clc/J
017468   STOCK Tg(Col1a1*3.6-Cyan)2Rowe/J
018322   STOCK Tg(Cp-EGFP)25Gaia/ReyaJ
006334   STOCK Tg(Gad1-EGFP)94Agmo/J
006340   STOCK Tg(Gad1-EGFP)98Agmo/J
007896   STOCK Tg(Gt(ROSA)26Sor-EGFP)I1Able/J
017952   STOCK Tg(Isl1-EGFP*)1Slp/J
023965   STOCK Tg(Krt17-EGFP)#Cou/J
012477   STOCK Tg(Myh6*/tetO-GCaMP2)1Mik/J
008579   STOCK Tg(PSCA-EGFP)1Witt/J
024578   STOCK Tg(Pax6-GFP/cre)1Rilm/J
023345   STOCK Tg(Pgk1-Ccnb1/EGFP)1Aklo/J
012276   STOCK Tg(Piwil2/EGFP)1Ghan/J
012277   STOCK Tg(Piwil4/EGFP)1Ghan/J
012452   STOCK Tg(Rr5-GFP/cre)1Sapc/J
006570   STOCK Tg(SMN2)89Ahmb Smn1tm1Msd Tg(Hlxb9-GFP)1Tmj/J
009606   STOCK Tg(Six2-EGFP/cre)1Amc/J
018148   STOCK Tg(Slc17a8-EGFP)1Edw/SealJ
013752   STOCK Tg(TCF/Lef1-HIST1H2BB/EGFP)61Hadj/J
003658   STOCK Tg(TIE2GFP)287Sato/J
021226   STOCK Tg(Thy1-Brainbow3.1)18Jrs/J
021225   STOCK Tg(Thy1-Brainbow3.1)3Jrs/J
021227   STOCK Tg(Thy1-Brainbow3.2)7Jrs/J
007788   STOCK Tg(Thy1-EGFP)MJrs/J
016981   STOCK Tg(Uchl1-HIST2H2BE/mCherry/EGFP*)FSout/J
025193   STOCK Tg(Vmn1r232-Mapt/EGFP)1Dlc/J
018281   STOCK Tg(Wnt7a-EGFP/cre)#Bhr/Mmjax
006129   STOCK Tg(Zp3-EGFP)1Dean/J
023724   STOCK Tg(mI56i-cre,EGFP)1Kc/J
017755   STOCK Tg(tetO-GCAMP2)12iRyu/J
005104   STOCK Tg(tetO-HIST1H2BJ/GFP)47Efu/J
005699   STOCK Tg(tetO-Ipf1,EGFP)956.6Macd/J
017918   STOCK Tg(tetO-MAML1*/EGFP)2Akar/J
017906   STOCK Tg(tetO-hop/EGFP,-COP4/mCherry)6Kftnk/J
012345   STOCK Tg(tetO-tdTomato,-Syp/EGFP*)1.1Luo/J
View Strains carrying other alleles of GFP     (365 strains)

View Strains carrying other alleles of CAG     (11 strains)

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Fluorescent Proteins/lacZ Systems

Phenotype

Phenotype Information

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Research Applications
This mouse can be used to support research in many areas including:

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Fluorescent Proteins

GFP related

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Fluorescent Proteins

Genes & Alleles

Gene & Allele Information provided by MGI

 
Allele Symbol Tg(CAG-EGFP)131Osb
Allele Name transgene insertion 131, Research Institute for Microbial Diseases, Osaka University
Allele Type Transgenic (Reporter)
Common Name(s) Osb-Y01; Tg(ACTB-EGFP)131Osb; Tg(ACTB-EGFP)Y01Osb; Tg(Act-EGFP)C14-Y01-FM131Osb; Tg(CAG-EGFP)C14-Y01-FM131Osb; Tg(act-EGFP)Y01Osb; Tg14(act-EGFP)ObsY01; TgN(act-EGFP)ObsC14-Yo1-FM1310; Y01;
Strain of OriginC57BL/6
Site of ExpressionAll of the tissues, with the exception of erythrocytes and hair, appear green under excitation light.
Expressed Gene GFP, Green Fluorescent Protein, jellyfish
Green Fluorescent Protein (GFP), derived from the jellyfish Aequorea victoria, is a versatile reporter molecule which has found use in many biological applications. In some constructs the original molecule has been modified in order to enhance its fluorescence intensity (EGFP, enhanced GFP). When utilized in a transgenic construct, tissue expressing sufficient amounts of GFP will fluoresce when exposed to a 488 nm light source.
Promoter CAG, CMV-IE enhancer/chicken beta-actin/rabbit beta-globin hybrid promoter,
General Note This transgene was made using the same construct as Tg(ACTB-EGFP)1Osb, but in this case it was injected into C57BL/6 fertilized oocytes. According to the Center for Animal Resources and Development Database (CARD R-Base), which distributes it, the transgene integrated on Chr 14D1.
Molecular Note The transgene comprises the cDNA encoding enhanced green fluorescent protein (EGFP), from the jellyfish Aequoria victoria, downstream of the "CAG promoter" -- which consists of the cytomegalovirus immediate early (CMV-EI) enhancer followed by a 1.3-kb DNA segment including the promoter, first exon and first intron of the chicken beta-actin gene, with the 3' splice junction sequence replaced by that of the rabbit hemoglobin beta gene -- and followed by the rabbit beta-hemoglobin polyadenylation signal and 3' flanking sequence. [MGI Ref ID J:87415]
 
 

Genotyping

Genotyping Information

Genotyping Protocols

Fluorescent Proteins (Generic GFP),

Probe


Fluorescent Proteins (Generic GFP), Standard PCR
Fluorescent Proteins -- Generic GFP, QPCR


Helpful Links

Genotyping resources and troubleshooting

References

References provided by MGI

Selected Reference(s)

Okabe M; Ikawa M; Kominami K; Nakanishi T; Nishimune Y. 1997. 'Green mice' as a source of ubiquitous green cells. FEBS Lett 407(3):313-9. [PubMed: 9175875]  [MGI Ref ID J:87415]

Additional References

Tg(CAG-EGFP)131Osb related

Badeanlou L; Furlan-Freguia C; Yang G; Ruf W; Samad F. 2011. Tissue factor-protease-activated receptor 2 signaling promotes diet-induced obesity and adipose inflammation. Nat Med 17(11):1490-7. [PubMed: 22019885]  [MGI Ref ID J:178106]

Chretien F; Dreyfus PA; Christov C; Caramelle P; Lagrange JL; Chazaud B; Gherardi RK. 2005. In vivo fusion of circulating fluorescent cells with dystrophin-deficient myofibers results in extensive sarcoplasmic fluorescence expression but limited dystrophin sarcolemmal expression. Am J Pathol 166(6):1741-8. [PubMed: 15920159]  [MGI Ref ID J:98788]

Davies PS; Powell AE; Swain JR; Wong MH. 2009. Inflammation and proliferation act together to mediate intestinal cell fusion. PLoS One 4(8):e6530. [PubMed: 19657387]  [MGI Ref ID J:152479]

Einstein O; Ben-Menachem-Tzidon O; Mizrachi-Kol R; Reinhartz E; Grigoriadis N; Ben-Hur T. 2006. Survival of neural precursor cells in growth factor-poor environment: implications for transplantation in chronic disease. Glia 53(4):449-55. [PubMed: 16345032]  [MGI Ref ID J:156140]

Engstrom L; Ruud J; Eskilsson A; Larsson A; Mackerlova L; Kugelberg U; Qian H; Vasilache AM; Larsson P; Engblom D; Sigvardsson M; Jonsson JI; Blomqvist A. 2012. Lipopolysaccharide-induced fever depends on prostaglandin E2 production specifically in brain endothelial cells. Endocrinology 153(10):4849-61. [PubMed: 22872578]  [MGI Ref ID J:191440]

Fu X; Zhao JX; Zhu MJ; Foretz M; Viollet B; Dodson MV; Du M. 2013. AMP-activated protein kinase alpha1 but not alpha2 catalytic subunit potentiates myogenin expression and myogenesis. Mol Cell Biol 33(22):4517-25. [PubMed: 24043309]  [MGI Ref ID J:206092]

Goldman DC; Bailey AS; Pfaffle DL; Al Masri A; Christian JL; Fleming WH. 2009. BMP4 regulates the hematopoietic stem cell niche. Blood 114(20):4393-401. [PubMed: 19759357]  [MGI Ref ID J:154923]

Hammond MD; Taylor RA; Mullen MT; Ai Y; Aguila HL; Mack M; Kasner SE; McCullough LD; Sansing LH. 2014. CCR2+ Ly6C(hi) inflammatory monocyte recruitment exacerbates acute disability following intracerebral hemorrhage. J Neurosci 34(11):3901-9. [PubMed: 24623768]  [MGI Ref ID J:209603]

Hara K; Kanai-Azuma M; Uemura M; Shitara H; Taya C; Yonekawa H; Kawakami H; Tsunekawa N; Kurohmaru M; Kanai Y. 2009. Evidence for crucial role of hindgut expansion in directing proper migration of primordial germ cells in mouse early embryogenesis. Dev Biol 330(2):427-39. [PubMed: 19371732]  [MGI Ref ID J:149220]

Hasegawa Y; Ogihara T; Yamada T; Ishigaki Y; Imai J; Uno K; Gao J; Kaneko K; Ishihara H; Sasano H; Nakauchi H; Oka Y; Katagiri H. 2007. Bone marrow (BM) transplantation promotes beta-cell regeneration after acute injury through BM cell mobilization. Endocrinology 148(5):2006-15. [PubMed: 17255204]  [MGI Ref ID J:129611]

Hofbauer JP; Heyder C; Denk U; Kocher T; Holler C; Trapin D; Asslaber D; Tinhofer I; Greil R; Egle A. 2011. Development of CLL in the TCL1 transgenic mouse model is associated with severe skewing of the T-cell compartment homologous to human CLL. Leukemia 25(9):1452-8. [PubMed: 21606964]  [MGI Ref ID J:175729]

Ieronimakis N; Hays A; Reyes M. 2012. Bone marrow-derived cells do not engraft into skeletal muscle microvasculature but promote angiogenesis after acute injury. Exp Hematol 40(3):238-249.e3. [PubMed: 22155292]  [MGI Ref ID J:191531]

Isami K; Haraguchi K; So K; Asakura K; Shirakawa H; Mori Y; Nakagawa T; Kaneko S. 2013. Involvement of TRPM2 in peripheral nerve injury-induced infiltration of peripheral immune cells into the spinal cord in mouse neuropathic pain model. PLoS One 8(7):e66410. [PubMed: 23935822]  [MGI Ref ID J:204357]

Kanatsu-Shinohara M; Morimoto T; Toyokuni S; Shinohara T. 2004. Regulation of mouse spermatogonial stem cell self-renewing division by the pituitary gland. Biol Reprod 70(6):1731-7. [PubMed: 14766726]  [MGI Ref ID J:132826]

Lau AW; Biester S; Cornall RJ; Forrester JV. 2008. Lipopolysaccharide-Activated IL-10-Secreting Dendritic Cells Suppress Experimental Autoimmune Uveoretinitis by MHCII-Dependent Activation of CD62L-Expressing Regulatory T Cells. J Immunol 180(6):3889-99. [PubMed: 18322197]  [MGI Ref ID J:133030]

Miki T; Shamma A; Kitajima S; Takegami Y; Noda M; Nakashima Y; Watanabe K; Takahashi C. 2010. The ss1-integrin-dependent function of RECK in physiologic and tumor angiogenesis. Mol Cancer Res 8(5):665-76. [PubMed: 20407016]  [MGI Ref ID J:205235]

Murai M; Yoneyama H; Ezaki T; Suematsu M; Terashima Y; Harada A; Hamada H; Asakura H; Ishikawa H; Matsushima K. 2003. Peyer's patch is the essential site in initiating murine acute and lethal graft-versus-host reaction. Nat Immunol 4(2):154-60. [PubMed: 12524535]  [MGI Ref ID J:94937]

Muramatsu M; Yamamoto S; Osawa T; Shibuya M. 2010. Vascular endothelial growth factor receptor-1 signaling promotes mobilization of macrophage lineage cells from bone marrow and stimulates solid tumor growth. Cancer Res 70(20):8211-21. [PubMed: 20924106]  [MGI Ref ID J:165563]

Nakanishi T; Kuroiwa A; Yamada S; Isotani A; Yamashita A; Tairaka A; Hayashi T; Takagi T; Ikawa M; Matsuda Y; Okabe M. 2002. FISH analysis of 142 EGFP transgene integration sites into the mouse genome. Genomics 80(6):564-74. [PubMed: 12504848]  [MGI Ref ID J:110379]

Ohtsuka M; Ogiwara S; Miura H; Mizutani A; Warita T; Sato M; Imai K; Hozumi K; Sato T; Tanaka M; Kimura M; Inoko H. 2010. Pronuclear injection-based mouse targeted transgenesis for reproducible and highly efficient transgene expression. Nucleic Acids Res 38(22):e198. [PubMed: 20880997]  [MGI Ref ID J:173808]

Powell AE; Anderson EC; Davies PS; Silk AD; Pelz C; Impey S; Wong MH. 2011. Fusion between Intestinal Epithelial Cells and Macrophages in a Cancer Context Results in Nuclear Reprogramming. Cancer Res 71(4):1497-505. [PubMed: 21303980]  [MGI Ref ID J:169371]

Rock JR; Onaitis MW; Rawlins EL; Lu Y; Clark CP; Xue Y; Randell SH; Hogan BL. 2009. Basal cells as stem cells of the mouse trachea and human airway epithelium. Proc Natl Acad Sci U S A 106(31):12771-5. [PubMed: 19625615]  [MGI Ref ID J:152012]

Rosin NL; Falkenham A; Sopel MJ; Lee TD; Legare JF. 2013. Regulation and Role of Connective Tissue Growth Factor in AngII-Induced Myocardial Fibrosis. Am J Pathol 182(3):714-26. [PubMed: 23287510]  [MGI Ref ID J:193265]

Ruud J; Wilhelms DB; Nilsson A; Eskilsson A; Tang YJ; Strohle P; Caesar R; Schwaninger M; Wunderlich T; Backhed F; Engblom D; Blomqvist A. 2013. Inflammation- and tumor-induced anorexia and weight loss require MyD88 in hematopoietic/myeloid cells but not in brain endothelial or neural cells. FASEB J 27(5):1973-80. [PubMed: 23395911]  [MGI Ref ID J:197842]

Schuettpelz LG; Borgerding JN; Christopher MJ; Gopalan PK; Romine MP; Herman AC; Woloszynek JR; Greenbaum AM; Link DC. 2014. G-CSF regulates hematopoietic stem cell activity, in part, through activation of Toll-like receptor signaling. Leukemia 28(9):1851-60. [PubMed: 24518205]  [MGI Ref ID J:213449]

Scroggins SM; Olivier AK; Meyerholz DK; Schlueter AJ. 2013. Characterization of regulatory dendritic cells that mitigate acute graft-versus-host disease in older mice following allogeneic bone marrow transplantation. PLoS One 8(9):e75158. [PubMed: 24040397]  [MGI Ref ID J:207548]

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Health & husbandry

Health & Colony Maintenance Information

Animal Health Reports

Room Number           AX10

Colony Maintenance

Breeding & HusbandryWhen maintaining a live colony, these mice are bred as hemizygotes. The Donating Investigator maintained the line using a hemizygote x hemizygote breeding scheme and has not tried to make the strain homozygous.
Mating System+/+ sibling x Hemizygote         (Female x Male)   02-MAY-08
Diet Information LabDiet® 5K52/5K67

Pricing and Purchasing

Pricing, Supply Level & Notes, Controls


Pricing for USA, Canada and Mexico shipping destinations View International Pricing

Live Mice

Price per mouse (US dollars $)GenderGenotypes Provided
Individual Mouse $232.00Female or MaleHemizygous for Tg(CAG-EGFP)131Osb  
Price per Pair (US dollars $)Pair Genotype
$304.00Hemizygous for Tg(CAG-EGFP)131Osb x Noncarrier  
$304.00Noncarrier x Hemizygous for Tg(CAG-EGFP)131Osb  

Standard Supply

Repository-Live.
Repository-Live represents an exclusive set of over 1800 unique mouse models across a vast array of research areas. Breeding colonies provide mice for large and small orders and fluctuate in size depending on current research demand. If a strain is not immediately available, you will receive an estimated availability timeframe for your inquiry or order in 2-3 business days. Repository strains typically are delivered at 4 to 8 weeks of age. Requests for specific ages will be noted but not guaranteed and we do not accept age requests for breeder pairs. However, if cohorts of mice (5 or more of one gender) are needed at a specific age range for experiments, we will do our best to accommodate your age request.

Pricing for International shipping destinations View USA Canada and Mexico Pricing

Live Mice

Price per mouse (US dollars $)GenderGenotypes Provided
Individual Mouse $301.60Female or MaleHemizygous for Tg(CAG-EGFP)131Osb  
Price per Pair (US dollars $)Pair Genotype
$395.20Hemizygous for Tg(CAG-EGFP)131Osb x Noncarrier  
$395.20Noncarrier x Hemizygous for Tg(CAG-EGFP)131Osb  

Standard Supply

Repository-Live.
Repository-Live represents an exclusive set of over 1800 unique mouse models across a vast array of research areas. Breeding colonies provide mice for large and small orders and fluctuate in size depending on current research demand. If a strain is not immediately available, you will receive an estimated availability timeframe for your inquiry or order in 2-3 business days. Repository strains typically are delivered at 4 to 8 weeks of age. Requests for specific ages will be noted but not guaranteed and we do not accept age requests for breeder pairs. However, if cohorts of mice (5 or more of one gender) are needed at a specific age range for experiments, we will do our best to accommodate your age request.

View USA Canada and Mexico Pricing View International Pricing

Standard Supply

Repository-Live.
Repository-Live represents an exclusive set of over 1800 unique mouse models across a vast array of research areas. Breeding colonies provide mice for large and small orders and fluctuate in size depending on current research demand. If a strain is not immediately available, you will receive an estimated availability timeframe for your inquiry or order in 2-3 business days. Repository strains typically are delivered at 4 to 8 weeks of age. Requests for specific ages will be noted but not guaranteed and we do not accept age requests for breeder pairs. However, if cohorts of mice (5 or more of one gender) are needed at a specific age range for experiments, we will do our best to accommodate your age request.

Control Information

  Control
   Noncarrier
   000664 C57BL/6J
 
  Considerations for Choosing Controls
  Control Pricing Information for Genetically Engineered Mutant Strains.
 

Payment Terms and Conditions

Terms are granted by individual review and stated on the customer invoice(s) and account statement. These transactions are payable in U.S. currency within the granted terms. Payment for services, products, shipping containers, and shipping costs that are rendered are expected within the payment terms indicated on the invoice or stated by contract. Invoices and account balances in arrears of stated terms may result in The Jackson Laboratory pursuing collection activities including but not limited to outside agencies and court filings.


See Terms of Use tab for General Terms and Conditions


The Jackson Laboratory's Genotype Promise

The Jackson Laboratory has rigorous genetic quality control and mutant gene genotyping programs to ensure the genetic background of JAX® Mice strains as well as the genotypes of strains with identified molecular mutations. JAX® Mice strains are only made available to researchers after meeting our standards. However, the phenotype of each strain may not be fully characterized and/or captured in the strain data sheets. Therefore, we cannot guarantee a strain's phenotype will meet all expectations. To ensure that JAX® Mice will meet the needs of individual research projects or when requesting a strain that is new to your research, we suggest ordering and performing tests on a small number of mice to determine suitability for your particular project.
Ordering Information
JAX® Mice
Surgical and Preconditioning Services
JAX® Services
Customer Services and Support
Tel: 1-800-422-6423 or 1-207-288-5845
Fax: 1-207-288-6150
Technical Support Email Form

Terms of Use

Terms of Use


General Terms and Conditions


Contact information

General inquiries regarding Terms of Use

Contracts Administration

phone:207-288-6470

JAX® Mice, Products & Services Conditions of Use

"MICE" means mouse strains, their progeny derived by inbreeding or crossbreeding, unmodified derivatives from mouse strains or their progeny supplied by The Jackson Laboratory ("JACKSON"). "PRODUCTS" means biological materials supplied by JACKSON, and their derivatives. "RECIPIENT" means each recipient of MICE, PRODUCTS, or services provided by JACKSON including each institution, its employees and other researchers under its control. MICE or PRODUCTS shall not be: (i) used for any purpose other than the internal research, (ii) sold or otherwise provided to any third party for any use, or (iii) provided to any agent or other third party to provide breeding or other services. Acceptance of MICE or PRODUCTS from JACKSON shall be deemed as agreement by RECIPIENT to these conditions, and departure from these conditions requires JACKSON's prior written authorization.

No Warranty

MICE, PRODUCTS AND SERVICES ARE PROVIDED “AS IS”. JACKSON EXTENDS NO WARRANTIES OF ANY KIND, EITHER EXPRESS, IMPLIED, OR STATUTORY, WITH RESPECT TO MICE, PRODUCTS OR SERVICES, INCLUDING ANY IMPLIED WARRANTY OF MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE, OR ANY WARRANTY OF NON-INFRINGEMENT OF ANY PATENT, TRADEMARK, OR OTHER INTELLECTUAL PROPERTY RIGHTS.

In case of dissatisfaction for a valid reason and claimed in writing by a purchaser within ninety (90) days of receipt of mice, products or services, JACKSON will, at its option, provide credit or replacement for the mice or product received or the services provided.

No Liability

In no event shall JACKSON, its trustees, directors, officers, employees, and affiliates be liable for any causes of action or damages, including any direct, indirect, special, or consequential damages, arising out of the provision of MICE, PRODUCTS or services, including economic damage or injury to property and lost profits, and including any damage arising from acts or negligence on the part of JACKSON, its agents or employees. Unless prohibited by law, in purchasing or receiving MICE, PRODUCTS or services from JACKSON, purchaser or recipient, or any party claiming by or through them, expressly releases and discharges JACKSON from all such causes of action or damages, and further agrees to defend and indemnify JACKSON from any costs or damages arising out of any third party claims.

MICE and PRODUCTS are to be used in a safe manner and in accordance with all applicable governmental rules and regulations.

The foregoing represents the General Terms and Conditions applicable to JACKSON’s MICE, PRODUCTS or services. In addition, special terms and conditions of sale of certain MICE, PRODUCTS or services may be set forth separately in JACKSON web pages, catalogs, price lists, contracts, and/or other documents, and these special terms and conditions shall also govern the sale of these MICE, PRODUCTS and services by JACKSON, and by its licensees and distributors.

Acceptance of delivery of MICE, PRODUCTS or services shall be deemed agreement to these terms and conditions. No purchase order or other document transmitted by purchaser or recipient that may modify the terms and conditions hereof, shall be in any way binding on JACKSON, and instead the terms and conditions set forth herein, including any special terms and conditions set forth separately, shall govern the sale of MICE, PRODUCTS or services by JACKSON.


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