Strain Name: |
B6SJL-Tg(Thy1-Stx1a/EYFP)1Sud/J |
|---|---|
Stock Number: |
007880 |
Availability: | Under Development for Cryopreservation Repository |
| To register your interest in this strain go to the Strain Interest Form. |
Price and Supply Information | |
General Terms and Conditions |
| Genes & Alleles | Stx1a; Thy1; YFP; Tg(Thy1-Stx1a/EYFP)1Sud; |
Product Information
Strain Details
Type JAX® GEMM® Strain - Mutant Stock Additional information on JAX® GEMM® Strains. Type JAX® GEMM® Strain - Transgenic Species laboratory mouse Donating Investigator Thomas Sudhof, U. of Texas, SW Medical Center at Dallas Strain Description
Mice homozygous for this transgene are viable and fertile and do not display any gross physical or behavioral abnormalities. The mice express a syntaxin 1A (brain)-enhanced yellow fluorescent protein fusion protein under the control of a Thy1 promoter. Fluorescence patterns have not been characterized.Strain Development
A transgenic vector was designed to create a mouse syntaxin 1A (brain)/enhanced yellow fluorescent protein (EYFP) fusion protein under the control of a mouse thymus cell antigen 1, theta (Thy1) promoter. The vector was introduced to B6SJLF1 fertilized oocytes. Founders were maintained on this mixed background through crosses to B6SJLF1 hybrid mice and intercrossing.
Gene & Allele Details
| Allele Symbol | Tg(Thy1-Stx1a/EYFP)1Sud | ||
|---|---|---|---|
| Allele Name | transgene insertion 1, Thomas C Sudhof | ||
| Common Name(s) | Syntaxin 1A-EYFP Tg; TXA; Tg(Thy1-EYFP-Stx1a)1Sud; | ||
| Strain of Origin | (C57BL/6 x SJL)F1 | ||
| Expressed Gene | Stx1a, syntaxin 1A (brain), mouse, laboratory | ||
| Expressed Gene | YFP, Yellow Fluorescent Protein, jellyfish | ||
| Yellow Fluorescent Protein (YFP) is a derivative of Green Fluorescent Protein (GFP), a versatile reporter molecule which has found use in many biological applications. The original molecule has been modified in order to enhance fluorescence intensity and shift the wavelength emitted when excited. When YFP is utilized in a transgenic construct, tissue expressing sufficient amounts of YFP will fluoresce yellowish-green when exposed to a 513 nm light source. | |||
| Promoter | Thy1, thymus cell antigen 1, theta, mouse, laboratory | ||
| Molecular Note | A transgenic vector was designed to create a mouse syntaxin 1A (brain)/enhanced yellow fluorescent protein (EYFP) fusion protein under the control of a mouse thymus cell antigen 1, theta (Thy1) promoter. [MGI Ref ID J:132968] | ||
Related Strains
Fluorescent Protein Strains
View Fluorescent Protein Strains (139 strains)
007879 STOCK Stx1atm2Sud/J
005483 129-Tg(CAG-EYFP)7AC5Nagy/J 006148 B6.129X1-Gt(ROSA)26Sortm1(EYFP)Cos/J 007901 B6.Cg-Tg(Thy1-Brainbow1.0)HLich/J 007911 B6.Cg-Tg(Thy1-Brainbow1.1)MLich/J 007921 B6.Cg-Tg(Thy1-Brainbow2.1)RLich/J 007612 B6.Cg-Tg(Thy1-COP4/EYFP)18Gfng/J 007615 B6.Cg-Tg(Thy1-COP4/EYFP)9Gfng/J 005630 B6.Cg-Tg(Thy1-EYFP)15Jrs/J 003709 B6.Cg-Tg(Thy1-YFP)16Jrs/J 005627 B6.Cg-Tg(Thy1-YFP/Syp)10Jrs/J 003782 B6.Cg-Tg(Thy1-YFPH)2Jrs/J 007606 B6.Cg-Tg(Thy1-cre/ESR1,-EYFP)AGfng/J 007910 B6;CBA-Tg(Thy1-Brainbow1.0)LLich/J 005620 B6;D2-Tg(S100B-EYFP)1Wjt/J 007610 B6;SJL-Tg(Thy1-cre/ESR1,-EYFP)VGfng/J 006618 C57BL/6-Tg(tetO-COX8A/EYFP)1Ksn/J 006362 C57BL/6J-Tg(CMV-Cox8a/EYFP)17J/J 005130 STOCK Gt(ROSA)26Sortm1(Smo/EYFP)Amc/J
Additional Web Information
Fluorescent Proteins/lacZ Systems
Research Applications
This mouse can be used to support research in many areas including:
YFP relatedNeurobiology Research
Fluorescent protein expression in neural tissue
Research Tools
Fluorescent Proteins
Research Tools
Fluorescent Proteins
References
Additional ReferencesPrice and Supply Information
| Strain Name: | B6SJL-Tg(Thy1-Stx1a/EYFP)1Sud/J |
| Stock Number: | 007880 |
This strain is currently Under Development for Cryopreservation Repository.
To register your interest in this strain go to the Strain Interest Form.
Estimated Available for Sale Date:
Please note: Estimated available for sale dates are provided to keep customers better informed on strains under development. Please note that our Colony Managers routinely monitor the target date and edit it based on breeding performance and other factors. The length of time it takes to make a new strain available for sale depends on genotype, age, number of animals sent by the Donating Investigator, breeding performance, additional strain development (backcrossing, making homozygous), and anticipated demand for the strain/interest registered.
View All Strains Under Development
Supply Details
| Standard Supply | Under Development for Cryopreservation Repository |
|---|---|
| Supply Notes |
This strain is included in the Induced Mutant Resource Colony collection. |
| Licensing | See General Terms and Conditions below for Licensing and Use Restrictions |
General Terms and Conditions
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The Jackson Laboratory has rigorous genetic quality control and mutant gene genotyping programs to ensure the genetic background of JAX® Mice strains as well as the genotypes of strains with identified molecular mutations. JAX® Mice strains are only made available to researchers after meeting our standards. However, the phenotype of each strain may not be fully characterized and/or captured in the strain data sheets. Therefore, we cannot guarantee a strain's phenotype will meet all expectations. To ensure that JAX® Mice will meet the needs of individual research projects or when requesting a strain that is new to your research, we suggest ordering and performing tests on a small number of mice to determine suitability for your particular project.Ordering and Purchasing Information
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