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- Description
- Phenotype
- Genes & alleles
- Genotyping
- Health & husbandry
- References
- Purchasing information
- Terms of Use
Description
Strain Information
Former Names B6(V)-Pafl/J (Changed: 04-MAR-08 ) Type Mutant Strain; Spontaneous Mutation; Additional information on Genetically Engineered Mutant Mice. Mating System Heterozygote x +/+ sibling (Female x Male) Mating System +/+ sibling x Hemizygote (Female x Male) Species laboratory mouse Generation N35+N2F6 Development
The bad hair day mutation arose spontaneously at The Jackson Laboratory in 2004 in the B6.V-Lepob/J strain. Two backcrosses were done to C57BL/6J to breed away from the Lepob mutation and the strain has sibling inbred since.
Control Information
| Control | ||
|---|---|---|
| Wild-type from the colony | ||
| Considerations for Choosing Controls | ||
Phenotype
Phenotype Information
View Mammalian Phenotype Terms
Mammalian Phenotype Terms
assigned by genotype
Bhrd/Bhrd
B6(V)-Bhrd/J
- skin/coat/nails phenotype
- abnormal hair growth (MGI Ref ID J:127794)
- sparse hair (MGI Ref ID J:127794)
- homozygous females are almost as bald as hemizygous males
Bhrd/Bhrd+
B6(V)-Bhrd/J
- skin/coat/nails phenotype
- abnormal coat appearance (MGI Ref ID J:127794)
- patchy hair (MGI Ref ID J:127794)
- heterozygous females have patches of fur missing in the coat
- abnormal hair growth (MGI Ref ID J:127794)
Bhrd/Y
B6(V)-Bhrd/JThis mouse can be used to support research in many areas including:Bhrd related
Dermatology Research
Skin and Hair Texture Defects
Developmental Biology Research
Skin and Hair Texture Defects
Genes & Alleles
Gene & Allele Information
| Allele Symbol | Bhrd | ||
|---|---|---|---|
| Allele Name | bad hair day | ||
| Allele Type | Spontaneous | ||
| Strain of Origin | B6.V-Lepob/J | ||
Genotyping
Genotyping Information
This strain will not have a genotyping protocol or one is not currently available.
Helpful Links
Optimizing PCR Protocols
References
References
Selected Reference(s)
Son Yong Karst; Patricia F. Ward-Bailey; Richard Samples; Kenneth R. Johnson; Leah Rae Donahue; Muriel T. Davisson. 2007. Bad hair day: a semidominant X-linked mutation affecting skin and hair. MGI Direct Data Submission :. [MGI Ref ID J:127794]
Health & husbandry
Health & Colony Maintenance Information
Animal Health Reports
Room Number A1
Colony Maintenance
Mating System Heterozygote x +/+ sibling (Female x Male) +/+ sibling x Hemizygote (Female x Male)
Purchasing information
Pricing, Supply Level & Notes, Controls, General Terms & Conditions
Pricing
| Pricing for USA, Canada and Mexico shipping destinations |
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Weeks of Age Price* Gender Genotypes Provided Individual Mouse Price $124.10 Male Hemizygous for Pafl $124.10 Female Heterozygous for Pafl *Price(s) in US dollars ($)
Pairs /Price* Pair Genotype $176.35 Heterozygous for Pafl x Wild-type for Pafl $176.35 Wild-type for Pafl x Hemizygous for Pafl
Additional Supply Details
| Supply Notes |
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| Pricing for International shipping destinations |
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Weeks of Age Price* Gender Genotypes Provided Individual Mouse Price $161.40 Male Hemizygous for Pafl $161.40 Female Heterozygous for Pafl *Price(s) in US dollars ($)
Pairs /Price* Pair Genotype $229.30 Heterozygous for Pafl x Wild-type for Pafl $229.30 Wild-type for Pafl x Hemizygous for Pafl
Additional Supply Details
| Supply Notes |
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Supply Details
| Standard Supply | Repository-Live. A collection of over 1000 strains maintained as live colonies. Individual colonies are sized to meet current customer demand. Delivery for orders of 10 mice or less ranges on average from one to eight weeks; mice are generally shipped between four to six weeks of age with a maximum shipping age of ~nine weeks. Colony sizes do not generally support stringent age specifications for large volumes of mice; however custom orders and larger quantities of mice are easily arranged. Estimated ship dates for all orders provided within 48 hours of order placement. |
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| Supply Notes |
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| Important Note | Although this line has been backcrossed twice to select against the Lepob mutation that was in the founder, there is a small chance that the recessive Lepob mutation might still be segregating in this strain. |
Control Information
| Control | ||
|---|---|---|
| Wild-type from the colony | ||
| Considerations for Choosing Controls | ||
| USA, Canada and Mexico - Control Pricing Information for Genetically Engineered Mutant Strains. | ||
| International - Control Pricing Information for Genetically Engineered Mutant Strains. | ||
General Terms and Conditions
See Terms of Use
The Jackson Laboratory's Genotype Promise
The Jackson Laboratory has rigorous genetic quality control and mutant gene genotyping programs to ensure the genetic background of JAX® Mice strains as well as the genotypes of strains with identified molecular mutations. JAX® Mice strains are only made available to researchers after meeting our standards. However, the phenotype of each strain may not be fully characterized and/or captured in the strain data sheets. Therefore, we cannot guarantee a strain's phenotype will meet all expectations. To ensure that JAX® Mice will meet the needs of individual research projects or when requesting a strain that is new to your research, we suggest ordering and performing tests on a small number of mice to determine suitability for your particular project.Ordering and Purchasing Information
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JAX® Mice Orders
Surgical Services
Contact Information
Orders & Technical Support
Tel: 800.422.6423 or 207.288.5845
Fax: 207.288.6150
Technical Support Email Form
Terms of Use
Terms of Use
General Terms and Conditions
Contact information
General inquiries
Contracts Administration
| phone: | 207-288-6470 |
| fax: | 207-288-6655 |
JAX® Mice & Services Conditions of Use
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