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Genes & Alleles

hlb497;

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Product Information

Strain Details

Type JAX® GEMM® Strain - Chemically Induced Mutation Additional information on JAX® GEMM® Strains. Type JAX® GEMM® Strain - Coisogenic Species laboratory mouse H2 Haplotype b

Mammalian Phenotype Terms assigned by genotype hlb497/hlb497         C57BL/6J-hlb497/J homeostasis/metabolism phenotype increased circulating triglyceride level (MGI Ref ID J:82961) an 8 week old male mouse exhibited plasma triglycerides of 163 mg/dl, repeat testing a week later resulted in a lower, but still elevated value of 117 mg/dl

Gene & Allele Details

Allele Symbol		hlb497
Allele Name		heart, lung and blood, 497
Strain of Origin		C57BL/6J
Molecular Note		This mutation was discovered in an ENU mutagenesis screen.

Research Applications

This mouse can be used to support research in many areas including:

Cardiovascular Research
Hypertriglyceridemia

References

Additional References

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Price and Supply Information

Strain Name:	C57BL/6J-hlb497/J
Stock Number:	008261

Price Details

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Supply Details

Standard Supply	Repository-Cryopreserved. Must Be Recovered. Please refer to pricing and supply notes for further information.
Supply Notes	Cryorecovery - Standard. The recovery process begins when a signed agreement form is returned to the Customer Service Department after order placement. Although results vary by strain, at least two males and two females (two pairs) will be provided, typically within 15 weeks of our receipt of the signed agreement form. If the first recovery attempt is unsuccessful or only one pair is recovered, a second recovery will be done, extending the delivery time to approximately 25 weeks. At least one member of each pair will be of known genotype and will carry the mutation if it is a mutant strain. Please note that pairs may not reflect the mating scheme utilized by The Jackson Laboratory prior to cryopreservation of the strain. Mating schemes are sometimes modified for successful cryopreservation. Price represents a repository maintenance fee, which includes the cost of recovery of the strain from the cryopreservation resource and the periodic replacement of the frozen embryos used for recovery. Cryorecovery to establish a Dedicated Supply for greater quantities of mice. One to two pairs will be recovered to establish a Dedicated Supply of mice. Price by quotation. For more information on Dedicated Supply, please contact JAX® Services: Tel: 1-800-422-6423 or 1-207-288-5845; Email: jaxservices@jax.org. This strain is included in the Mouse Heart, Lung, Blood and Sleep Disorders Center collection.
Licensing	See General Terms and Conditions below

General Terms and Conditions

View JAX^® Mice & Services Conditions of Use.

The Jackson Laboratory's Genotype Promise

The Jackson Laboratory has rigorous genetic quality control and mutant gene genotyping programs to ensure the genetic background of JAX^® Mice strains as well as the genotypes of strains with identified molecular mutations. JAX^® Mice strains are only made available to researchers after meeting our standards. However, the phenotype of each strain may not be fully characterized and/or captured in the strain data sheets. Therefore, we cannot guarantee a strain's phenotype will meet all expectations. To ensure that JAX^® Mice will meet the needs of individual research projects or when requesting a strain that is new to your research, we suggest ordering and performing tests on a small number of mice to determine suitability for your particular project.

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