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Strain Name:

C57BL/6J-hlb145/J

Stock Number:

008264

Availability:

Repository-Cryopreserved


General Terms and Conditions

Genes & Alleles   hlb145;


Product Information

Strain Details

Type JAX® GEMM® Strain - Chemically Induced Mutation
Additional information on JAX® GEMM® Strains.
Type JAX® GEMM® Strain - Coisogenic
Specieslaboratory mouse
H2 Haplotypeb

Strain Description
For information on hlb145 view the web page on the Mouse Heart, Lung, Blood and Sleep Disorders Center site.

Mammalian Phenotype Terms assigned by genotype

hlb145/?

        C57BL/6J-hlb145/J
  • hematopoietic system phenotype
  • decreased leukocyte cell number (MGI Ref ID J:82961)
    • at 7 weeks of age, the index mouse had a WBC of 2.7 x 103 cells/microliter; retesting at 9 weeks confirmed leukopenia
  • immune system phenotype
  • decreased leukocyte cell number (MGI Ref ID J:82961)
    • at 7 weeks of age, the index mouse had a WBC of 2.7 x 103 cells/microliter; retesting at 9 weeks confirmed leukopenia

Gene & Allele Details

Allele Symbol hlb145
Allele Name heart, lung and blood, 145
Strain of OriginC57BL/6J
Molecular Note This mutation was discovered in an ENU mutagenesis screen for blood anomalies.

Research Applications

This mouse can be used to support research in many areas including:

Hematological Research

Immunology and Inflammation Research
Immunodeficiency

References

Additional References

Price and Supply Information

Strain Name: C57BL/6J-hlb145/J
Stock Number: 008264

Price Details

IMPORTANT NOTE: Prices are based on shipping destination. To view prices, select your shipping destination.

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Supply Details

Standard SupplyRepository-Cryopreserved. Must Be Recovered. Please refer to pricing and supply notes for further information.
Supply Notes Cryorecovery - Standard.
The recovery process begins when a signed agreement form is returned to the Customer Service Department after order placement. Although results vary by strain, at least two males and two females (two pairs) will be provided, typically within 15 weeks of our receipt of the signed agreement form. If the first recovery attempt is unsuccessful or only one pair is recovered, a second recovery will be done, extending the delivery time to approximately 25 weeks. At least one member of each pair will be of known genotype and will carry the mutation if it is a mutant strain. Please note that pairs may not reflect the mating scheme utilized by The Jackson Laboratory prior to cryopreservation of the strain. Mating schemes are sometimes modified for successful cryopreservation. Price represents a repository maintenance fee, which includes the cost of recovery of the strain from the cryopreservation resource and the periodic replacement of the frozen embryos used for recovery.

Cryorecovery to establish a Dedicated Supply for greater quantities of mice.
One to two pairs will be recovered to establish a Dedicated Supply of mice. Price by quotation. For more information on Dedicated Supply, please contact JAX® Services: Tel: 1-800-422-6423 or 1-207-288-5845; Email: jaxservices@jax.org.
This strain is included in the Mouse Heart, Lung, Blood and Sleep Disorders Center collection.

LicensingSee General Terms and Conditions below  

General Terms and Conditions

View JAX® Mice & Services Conditions of Use.

The Jackson Laboratory's Genotype Promise

The Jackson Laboratory has rigorous genetic quality control and mutant gene genotyping programs to ensure the genetic background of JAX® Mice strains as well as the genotypes of strains with identified molecular mutations. JAX® Mice strains are only made available to researchers after meeting our standards. However, the phenotype of each strain may not be fully characterized and/or captured in the strain data sheets. Therefore, we cannot guarantee a strain's phenotype will meet all expectations. To ensure that JAX® Mice will meet the needs of individual research projects or when requesting a strain that is new to your research, we suggest ordering and performing tests on a small number of mice to determine suitability for your particular project.
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