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Strain Name:

129S1/SvImJ-Myo6sv-4J/J

Stock Number:

008456

Availability:

Repository- Live


General Terms and Conditions

Genes & Alleles   Myo6;   Myo6sv-4J;


Product Information

Strain Details

Type JAX® GEMM® Strain - Coisogenic
Additional information on JAX® GEMM® Strains.
Type JAX® GEMM® Strain - Spontaneous Mutation
Specieslaboratory mouse
GenerationF56+7 (20-JUN-08)
Mammalian Phenotype Terms assigned by genotype

Myo6sv-4J/Myo6sv-4J

        129S1/SvImJ-Myo6sv-4J/J
  • hearing/vestibular/ear phenotype
  • absent brainstem auditory evoked potential (MGI Ref ID J:135836)
    • at 6 to 7 weeks of age 100 dB SPL evoked no response
  • circling (MGI Ref ID J:135836)
  • deafness (MGI Ref ID J:135836)
  • head shaking (MGI Ref ID J:135836)
  • head tossing (MGI Ref ID J:135836)
  • behavior/neurological phenotype
  • circling (MGI Ref ID J:135836)
  • head shaking (MGI Ref ID J:135836)
  • head tossing (MGI Ref ID J:135836)

Gene & Allele Details

Allele Symbol Myo6sv-4J
Allele Name Snell's waltzer 4 Jackson
Strain of Origin129S1/SvImJ
Gene Symbol and Name Myo6, myosin VI
Chromosome 9
Gene Common Name(s) BC029719; DFNA22; DFNB37; KIAA0389; RGD1560646; Snell's waltzer; cDNA sequence BC029719; sv;
Molecular Note Non-complementation with the sv-2J allele proved this spontaneous mutation allelic.

Control Information

  Control
   Heterozygote from the colony
   002448 129S1/SvImJ
 
  Considerations for Choosing Controls

Related Strains

Strains carrying other alleles of Myo6
000578   B6 x STOCK Tyrc-ch Bmp5se +/+ Myo6sv/J
006124   B6.Cg-Myo6sv-2J/J
005749   C57BL/6J-Myo6sv-3J/J
View Strains carrying other alleles of Myo6     (3 strains)

Animal Health Reports

Room Number           A1

References

Selected Reference(s)

Kane K; Johnson KR. 2008. Snell's waltzer 4J, a new spontaneous mutation in the Myo6 gene MGI Direct Data Submission :.  [MGI Ref ID J:135836]


Price and Supply Information

Strain Name: 129S1/SvImJ-Myo6sv-4J/J
Stock Number: 008456

Price Details

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Supply Details

Standard SupplyRepository-Live. A collection of over 1000 strains maintained as live colonies. Individual colonies are sized to meet current customer demand. Delivery for orders of 10 mice or less ranges on average from one to eight weeks; mice are generally shipped between four to six weeks of age with a maximum shipping age of ~nine weeks. Colony sizes do not generally support stringent age specifications for large volumes of mice; however custom orders and larger quantities of mice are easily arranged. Estimated ship dates for all orders provided within 48 hours of order placement.
Supply Notes Usually shipped between four and eight weeks of age.
This strain is included in the Mouse Mutant Resource collection.
Genomic DNA is available for this strain from the Mouse DNA Resource.
LicensingSee General Terms and Conditions below  
Control InformationView Control Information in Strain Details.

General Terms and Conditions

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The Jackson Laboratory's Genotype Promise

The Jackson Laboratory has rigorous genetic quality control and mutant gene genotyping programs to ensure the genetic background of JAX® Mice strains as well as the genotypes of strains with identified molecular mutations. JAX® Mice strains are only made available to researchers after meeting our standards. However, the phenotype of each strain may not be fully characterized and/or captured in the strain data sheets. Therefore, we cannot guarantee a strain's phenotype will meet all expectations. To ensure that JAX® Mice will meet the needs of individual research projects or when requesting a strain that is new to your research, we suggest ordering and performing tests on a small number of mice to determine suitability for your particular project.
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