Strain Name:

ILSXISS123/TejJ

Stock Number:

009295

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Cryopreserved - Ready for recovery

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Common Names: LXS123;    
The ILSXISS#/Tej recombinant inbred (RI) strains originate from crosses between ILS/IbgTejJ (009324) and ISS/IbgTejJ (009325) They may be used to study the genetics of neurogenetic, neuropharmacological and behavioral phenotypes involved in alcohol-related traits and complex or potentially complex physiologic phenotypes (including differences in longevity under ad libitum and dietary restriction conditions, aging, body temperature and body weight).

Description

The genotypes of the animals provided may not reflect those discussed in the strain description or the mating scheme utilized by The Jackson Laboratory prior to cryopreservation. Please inquire for possible genotypes for this specific strain.

Strain Information

Type Recombinant Inbred (RI);
Additional information on Recombinant Inbred Mice.
Visit our online Nomenclature tutorial.
Specieslaboratory mouse
RI progenitor ILS/IbgTejJ ISS/IbgTejJ
GenerationF34+F2
Generation Definitions
 
Donating Investigator Thomas Johnson,   University of Colorado at Boulder

Description
The ILSXISS recombinant inbred (RI) strains are used to study the genetics of neurogenetic, neuropharmacological and behavioral phenotypes involved in alcohol-related traits including ethanol-induced loss of righting, psychomotor activation, hypothermia, blood ethanol concentration at wakening and numerous morphometric CNS traits as well as complex or potentially complex physiologic phenotypes including differences in longevity under ad libitum and dietary restriction conditions, aging, body temperature and body weight.

The strain distribution pattern (SDP) for the ILSXISS RI strains is available through Gene Network. Additional tools and information are presented through the Mouse Phenome Database Specialized Strain Panel Query Form, and Gene Network.

Development
The ILSXISS#/Tej (formerly LXS) recombinant inbred lines were generated from crosses between ILS/Ibg (Inbred Long Sleep)(009324) and ISS/Ibg(Inbred Short Sleep) (009325). These two progenitor strains were developed from the LS and SS selected lines derived from a heterogenous stock derived from an 8 way cross (A, AKR, BALB/c, C3H/2, C57BL, DBA/2, IS/Bi and RIII) created at the Cancer Research Genetics Laboratory at the University of California, Berkley. ILS and ISS are the product of inbreeding LS and SS, lines selected for long or short duration of loss-of-righting response following high dose intraperitoneal administration of ethanol.

The ILSXISS set was initiated in the laboratory of John DeFries and colleagues at the Institute of Behavioral Genetics, Boulder CO in 1996. Crosses at the F2 generation ensured that the Y chromosome and mitochondrial genes were randomly segregating. Three hundred-thirty MIT markers were used for screening. Seventy-seven RI strains reached the 22nd generation of inbreeding, however, since that time, a number have become extinct. Approximately 65 lines and the progenitors were donated to The Jackson Laboratory Repository in 2009 by Dr. Thomas E. Johnson and Dr. Jerry Stitzel at the University of Colorado, Boulder.

Control Information

  Control
   None Available
 
  Considerations for Choosing Controls

Related Strains

ILSXISS Strains
009324   ILS/IbgTejJ
009287   ILSXISS100/TejJ
009322   ILSXISS101/TejJ
009288   ILSXISS102/TejJ
009289   ILSXISS103/TejJ
009290   ILSXISS107/TejJ
009291   ILSXISS110/TejJ
009323   ILSXISS112/TejJ
009292   ILSXISS114/TejJ
009293   ILSXISS115/TejJ
009294   ILSXISS122/TejJ
009260   ILSXISS13/TejJ
009261   ILSXISS14/TejJ
009262   ILSXISS16/TejJ
009263   ILSXISS19/TejJ
009264   ILSXISS22/TejJ
009265   ILSXISS23/TejJ
009300   ILSXISS24/TejJ
009301   ILSXISS25/TejJ
009302   ILSXISS26/TejJ
009266   ILSXISS28/TejJ
009257   ILSXISS3/TejJ
009303   ILSXISS32/TejJ
009304   ILSXISS34/TejJ
009267   ILSXISS36/TejJ
009306   ILSXISS39/TejJ
009268   ILSXISS41/TejJ
009307   ILSXISS42/TejJ
009308   ILSXISS43/TejJ
009269   ILSXISS46/TejJ
009270   ILSXISS48/TejJ
009271   ILSXISS49/TejJ
009258   ILSXISS5/TejJ
009309   ILSXISS50/TejJ
009272   ILSXISS51/TejJ
009273   ILSXISS52/TejJ
009311   ILSXISS60/TejJ
009312   ILSXISS64/TejJ
009275   ILSXISS66/TejJ
009259   ILSXISS7/TejJ
009276   ILSXISS70/TejJ
009277   ILSXISS73/TejJ
009278   ILSXISS75/TejJ
009279   ILSXISS76/TejJ
009315   ILSXISS78/TejJ
009297   ILSXISS8/TejJ
009316   ILSXISS80/TejJ
009317   ILSXISS84/TejJ
009280   ILSXISS86/TejJ
009318   ILSXISS87/TejJ
009281   ILSXISS89/TejJ
009298   ILSXISS9/TejJ
009282   ILSXISS90/TejJ
009283   ILSXISS92/TejJ
009319   ILSXISS93/TejJ
009284   ILSXISS94/TejJ
009320   ILSXISS96/TejJ
009285   ILSXISS97/TejJ
009321   ILSXISS98/TejJ
009286   ILSXISS99/TejJ
009325   ISS/IbgTejJ
View ILSXISS Strains     (61 strains)

Phenotype

Phenotype Information

View Phenotypic Data

Phenotypic Data
Mouse Phenome Database
View Research Applications

Research Applications
This mouse can be used to support research in many areas including:

Research Tools
Genetics Research
      Gene Mapping
      Gene Mapping: Tools for QTL Mapping, Segregation and Linkage Analysis

Genes & Alleles

Gene & Allele Information provided by MGI

Currently there are no related genes or alleles for this strain.

Genotyping

Genotyping Information


Helpful Links

Genotyping resources and troubleshooting

References

References provided by MGI

Currently there are no available references for this strain.

Health & husbandry

Health & Colony Maintenance Information

Animal Health Reports

Production of mice from cryopreserved embryos or sperm occurs in a maximum barrier room, G200.

Pricing and Purchasing

Pricing, Supply Level & Notes, Controls


Pricing for USA, Canada and Mexico shipping destinations View International Pricing

Cryopreserved

Cryopreserved Mice - Ready for Recovery

Price (US dollars $)
Cryorecovery* $2525.00
Animals Provided

At least two mice that carry the mutation (if it is a mutant strain) will be provided. Their genotypes may not reflect those discussed in the strain description. Please inquire for possible genotypes and see additional details below.

Frozen Products

Price (US dollars $)
Frozen Embryo $1650.00

Standard Supply

Cryopreserved. Ready for recovery. Please refer to pricing and supply notes on the strain data sheet for further information.

Supply Notes

  • Cryopreserved Embryos
    Available to most shipping destinations1
    This strain is also available as cryopreserved embryos2. Orders for cryopreserved embryos may be placed with our Customer Service Department. Experienced technicians at The Jackson Laboratory have recovered frozen embryos of this strain successfully. We will provide you enough embryos to perform two embryo transfers. The Jackson Laboratory does not guarantee successful recovery at your facility. For complete information on purchasing embryos, please visit our Cryopreserved Embryos web page.

    1 Shipments cannot be made to Australia due to Australian government import restrictions.
    2 Embryos for most strains are cryopreserved at the two cell stage while some strains are cryopreserved at the eight cell stage. If this information is important to you, please contact Customer Service.
  • Cryorecovery - Standard.
    Progeny testing is not required.

    The average number of mice provided from recovery of our cryopreserved strains is 10. The total number of animals provided, their gender and genotype will vary. We will fulfill your order by providing at least two pair of mice, at least one animal of each pair carrying the mutation of interest. Please inquire if larger numbers of animals with specific genotype and genders are needed. Animals typically ship between 10 and 14 weeks from the date of your order. If a second cryorecovery is needed in order to provide the minimum number of animals, animals will ship within 25 weeks. IMPORTANT NOTE: The genotypes of animals provided may not reflect the mating scheme utilized by The Jackson Laboratory prior to cryopreservation, or that discussed in the strain description. Please inquire about possible genotypes which will be recovered for this specific strain. The Jackson Laboratory cannot guarantee the reproductive success of mice shipped to your facility. If the mice are lost after the first three days (post-arrival) or do not produce progeny at your facility, a new order and fee will be necessary.

    Cryorecovery to establish a Dedicated Supply for greater quantities of mice. Mice recovered can be used to establish a dedicated colony to contractually supply you mice according to your requirements. Price by quotation. For more information on Dedicated Supply, please contact JAX® Services, Tel: 1-800-422-6423 (from U.S.A., Canada or Puerto Rico only) or 1-207-288-5845 (from any location).

Pricing for International shipping destinations View USA Canada and Mexico Pricing

Cryopreserved

Cryopreserved Mice - Ready for Recovery

Price (US dollars $)
Cryorecovery* $3283.00
Animals Provided

At least two mice that carry the mutation (if it is a mutant strain) will be provided. Their genotypes may not reflect those discussed in the strain description. Please inquire for possible genotypes and see additional details below.

Frozen Products

Price (US dollars $)
Frozen Embryo $2145.00

Standard Supply

Cryopreserved. Ready for recovery. Please refer to pricing and supply notes on the strain data sheet for further information.

Supply Notes

  • Cryopreserved Embryos
    Available to most shipping destinations1
    This strain is also available as cryopreserved embryos2. Orders for cryopreserved embryos may be placed with our Customer Service Department. Experienced technicians at The Jackson Laboratory have recovered frozen embryos of this strain successfully. We will provide you enough embryos to perform two embryo transfers. The Jackson Laboratory does not guarantee successful recovery at your facility. For complete information on purchasing embryos, please visit our Cryopreserved Embryos web page.

    1 Shipments cannot be made to Australia due to Australian government import restrictions.
    2 Embryos for most strains are cryopreserved at the two cell stage while some strains are cryopreserved at the eight cell stage. If this information is important to you, please contact Customer Service.
  • Cryorecovery - Standard.
    Progeny testing is not required.

    The average number of mice provided from recovery of our cryopreserved strains is 10. The total number of animals provided, their gender and genotype will vary. We will fulfill your order by providing at least two pair of mice, at least one animal of each pair carrying the mutation of interest. Please inquire if larger numbers of animals with specific genotype and genders are needed. Animals typically ship between 10 and 14 weeks from the date of your order. If a second cryorecovery is needed in order to provide the minimum number of animals, animals will ship within 25 weeks. IMPORTANT NOTE: The genotypes of animals provided may not reflect the mating scheme utilized by The Jackson Laboratory prior to cryopreservation, or that discussed in the strain description. Please inquire about possible genotypes which will be recovered for this specific strain. The Jackson Laboratory cannot guarantee the reproductive success of mice shipped to your facility. If the mice are lost after the first three days (post-arrival) or do not produce progeny at your facility, a new order and fee will be necessary.

    Cryorecovery to establish a Dedicated Supply for greater quantities of mice. Mice recovered can be used to establish a dedicated colony to contractually supply you mice according to your requirements. Price by quotation. For more information on Dedicated Supply, please contact JAX® Services, Tel: 1-800-422-6423 (from U.S.A., Canada or Puerto Rico only) or 1-207-288-5845 (from any location).

View USA Canada and Mexico Pricing View International Pricing

Standard Supply

Cryopreserved. Ready for recovery. Please refer to pricing and supply notes on the strain data sheet for further information.

General Supply Notes

  • This strain is included in the Special Mutant Stock Resource collection.

Control Information

  Control
   None Available
 
  Considerations for Choosing Controls
  Control Pricing Information for Genetically Engineered Mutant Strains.
 

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Terms are granted by individual review and stated on the customer invoice(s) and account statement. These transactions are payable in U.S. currency within the granted terms. Payment for services, products, shipping containers, and shipping costs that are rendered are expected within the payment terms indicated on the invoice or stated by contract. Invoices and account balances in arrears of stated terms may result in The Jackson Laboratory pursuing collection activities including but not limited to outside agencies and court filings.


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The Jackson Laboratory has rigorous genetic quality control and mutant gene genotyping programs to ensure the genetic background of JAX® Mice strains as well as the genotypes of strains with identified molecular mutations. JAX® Mice strains are only made available to researchers after meeting our standards. However, the phenotype of each strain may not be fully characterized and/or captured in the strain data sheets. Therefore, we cannot guarantee a strain's phenotype will meet all expectations. To ensure that JAX® Mice will meet the needs of individual research projects or when requesting a strain that is new to your research, we suggest ordering and performing tests on a small number of mice to determine suitability for your particular project.
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