JAX Mice Database - 100410 WBB6F1/J-Kit<W>/Kit<W-v>/J

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Strain Name:	WBB6F1/J-Kit^W/Kit^W-v/J
Stock Number:	100410
Availability:	Level 2

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General Terms and Conditions

Former Name	WBB6F1/J-Kit^W/Kit^W-v (Changed: 23-FEB-06 )
Genes & Alleles	Kit; Kit^W-v; Kit^W; Pde6b; Pde6b^rd1;

Product Information

Strain Details

Type *F1 Hybrid

Additional information on Hybrid Strains.

Type JAX^® GEMM^® Strain - Mutant Stock

Additional information on JAX^® GEMM^® Strains.

Type JAX^® GEMM^® Strain - Spontaneous Mutation

Species laboratory mouse

Appearance
black eyed, white coat, affected
Related Genotype: a/a Kit^W/Kit^W-v

black with white belly, spot occasionally has white head blaze, tail has white tip, affected
Related Genotype: a/a Kit^W/+

grey with light belly and white spot, light tail, affected
Related Genotype: a/a Kit^W-v/+

black, unaffected
Related Genotype: a/a +/+
Important Note
This strain is heterozygous for the retinal degeneration allele Pde6b^rd1.
Strain Description
Kit mutant mice possess pleiotropic defects in pigment-forming cells, germ cells, RBC's and mast cells. In addition, they exhibit impaired resistance to parasitic infection and an intrinsic progenitor cell defect. Kit^W-v homozygotes resemble Kit^W homozygotes in color, anemia, and germ cells, but many of them survive to maturity. The lack of germ cells in mutant mice leads to the development of some ovarian tumors (mesotheliomas and granulosa cell), associated with an overproduction of pituitary gonadotropic hormone. Kit^W/Kit^W-v double heterozygotes are viable but sterile because of germ cell deficiency. They are also mast cell deficient. Kit^W/Kit^W-v double heterozygotes lack intermediate cells, derived from melanoblasts, in the stria vascularis resulting in endocochlear degeneration, loss of endocochlear potential, and hearing impairment.

Mammalian Phenotype Terms assigned by genotype

Kit^W/Kit^W-v
involves: C57BL/6 * WB
digestive/alimentary phenotype

peptic ulcer (J:6393)

40% developed prepyloric ulcer, however no duodenal ulcers were found

tumorigenesis

papilloma (J:6393)

40% developed forestomach papillomas

esophageal papilloma (J:6393)

observed papillomas in the lower end of the esophagus but not in the upper two-thirds of the esophagus

immune system phenotype

abnormal response to transplant (J:6084)

after receiving splenocytes from Kitl/Kitl donors, 15 weeks later, mice exhibit significant increase in mast cell numbers in skin, stomach and mesentery

after receiving skin grafts from Kitl/Kitl donors, no increase in mast cell number in skin is seen, compared to increase observed in reciprocal transplant

Kit^W/Kit^W-v
(WB/ReJ Kit^W x C57BL/6J-Kit^W-v/J)F1-Kit^W/Kit^W-v/J
life span-post-weaning/aging

abnormal induced morbidity/mortality (J:113500)

significantly higher mortality is exhibited by mutants (88%) by day 21 after induction of anti-GBM GN than wild type (25%)

cardiovascular system phenotype

altered response to myocardial infarction (J:106065)

exhibit worse heart function and greater cardiac dilatation at 35 days after myocardial infarction than wild-type, showing decreased left ventricle end-systolic pressure and left ventricle thickness, increased left ventricle end-systolic volume, heart-to-body weight ratio, septal wall thickness, percentage of left ventricle infracted and collagen content, and significantly different stoke volume, and positive and negative dp/dt

wild type bone marrow transplanted into mutant mice rescues the adverse cardiac remodeling and impaired cardiac function after myocardial infarction and shows increased mobilization of angiogenic and natural killer cells

increased infarction size (J:106065)

35 days after myocardial infarction show increased percentage of left ventricle infracted

decreased vascular permeability (J:84660)

do not display increased vascular permeability in the dura mater in response to acute restrain stress as is seen in wild-type controls

homeostasis/metabolism phenotype

abnormal interferon level (J:131785)

treatment with Hrh4 antagonist (JNJ 10191584) during ovalbumin challenge results in decreased levels of IFN-gamma

abnormal interleukin level (J:131785)

treatment with Hrh4 antagonist (JNJ 10191584) during ovalbumin challenge results in decreased levels of IL-4 (51%), IL-5 (35%), IL-6 (39%), and IL-17 (39%) in cultured peribronchiolar lymph nodes

altered response to myocardial infarction (J:106065)

exhibit worse heart function and greater cardiac dilatation at 35 days after myocardial infarction than wild-type, showing decreased left ventricle end-systolic pressure and left ventricle thickness, increased left ventricle end-systolic volume, heart-to-body weight ratio, septal wall thickness, percentage of left ventricle infracted and collagen content, and significantly different stoke volume, and positive and negative dp/dt

wild type bone marrow transplanted into mutant mice rescues the adverse cardiac remodeling and impaired cardiac function after myocardial infarction and shows increased mobilization of angiogenic and natural killer cells

increased infarction size (J:106065)

35 days after myocardial infarction show increased percentage of left ventricle infracted

increased porphyrin level (J:5985)

moderate but significant increase in protoporphrin levels in red blood cells compared to controls

proteinuria (J:113500)

mice develop increased proteinuria compared to wild type, 7 and 14 days after induction of anti-glomerular basement membrane (GBM) glomerulonephritis (GN)

immune system phenotype

*normal* immune system phenotype (J:125656)

sensitized mice have a normal early phase reaction (initial phase of bronchoconstriction) after ovalbumin challenge

abnormal interferon level (J:131785)

treatment with Hrh4 antagonist (JNJ 10191584) during ovalbumin challenge results in decreased levels of IFN-gamma

abnormal interleukin level (J:131785)

treatment with Hrh4 antagonist (JNJ 10191584) during ovalbumin challenge results in decreased levels of IL-4 (51%), IL-5 (35%), IL-6 (39%), and IL-17 (39%) in cultured peribronchiolar lymph nodes

decreased inflammatory response (J:131785)

treatment with Hrh4 antagonist (JNJ 10191584) during ovalbumin challenge results in decreased total bronchoalveolar lavage cell numbers (54%) and eosinophils (75%)

kidney inflammation (J:113500)

more T cells and macrophages infiltrate kidneys compared to control mice; increased numbers of CD4+ T cells and macrophages are found in glomeruli compared to controls on day 14 after anti-GBM GN

renal/urinary system phenotype

abnormal renal glomerulus morphology (J:113500)

in mice there is accumulation of PAS stain-positive material as well as crescent formation in glomeruli, compared to wild type

kidney inflammation (J:113500)

more T cells and macrophages infiltrate kidneys compared to control mice; increased numbers of CD4+ T cells and macrophages are found in glomeruli compared to controls on day 14 after anti-GBM GN

proteinuria (J:113500)

mice develop increased proteinuria compared to wild type, 7 and 14 days after induction of anti-glomerular basement membrane (GBM) glomerulonephritis (GN)

hematopoietic system phenotype

abnormal red blood cell (J:5985)

moderate but significant increase in protoporphrin levels in red blood cells compared to controls

The following phenotype information may relate to a genetic background differing from this JAX^® Mice strain.
Kit^W/Kit^W-v
involves: C57BL/6J
liver/biliary system phenotype

hepatic steatosis (J:125831)

seen in P7.5 mutants and adults

Gene & Allele Details

Allele Symbol		Kit^W-v
Allele Name		viable dominant spotting
Common Name(s)		W^v; Wv;
Strain of Origin		C57BL
Gene Symbol and Name		Kit, kit oncogene
Chromosome		5
Gene Common Name(s)		Bs; C-Kit; CD117; Dominant white spotting; Fdc; Gsfsco1; Gsfsco5; Gsfsow3; PBT; SCFR; SCO1; SCO5; SOW3; Ssm; Steel Factor Receptor; Tr-kit; W; belly-spot; dominant spotting; gsf spotted coat 1; gsf spotted coat 5; phenotype like Sl or W 3; spotted sterile male;
Molecular Note		A C to T point mutation at nucleotide 2007 results in a threonine to methionine substitution at amino acid 660. [J:24351]

Allele Symbol		Kit^W
Allele Name		dominant spotting
Common Name(s)		W;
Strain of Origin		old mutant of the mouse fancy
Gene Symbol and Name		Kit, kit oncogene
Chromosome		5
Gene Common Name(s)		Bs; C-Kit; CD117; Dominant white spotting; Fdc; Gsfsco1; Gsfsco5; Gsfsow3; PBT; SCFR; SCO1; SCO5; SOW3; Ssm; Steel Factor Receptor; Tr-kit; W; belly-spot; dominant spotting; gsf spotted coat 1; gsf spotted coat 5; phenotype like Sl or W 3; spotted sterile male;
General Note		This is an old mutant of the mouse fancy. Kit^W mutants are a potential model for human inherited pure red cell anemia, called Diamond-Blackfan anemia (OMIM 205900), but mouse mutants do not respond to corticosteroid treatment as do human patients. Thus, the mechanism of anemia causation in the two conditions must be different (J:14286).
Molecular Note		A guanosine to adenosine substitution at the first nucleotide at the 5' boundary of the intron following the transmembrane exon results in two different aberrantly spliced transcripts putatively expressed in a tissue specific manner. A deletion of 107 bp was found in transcripts from mast cells of mutant mice. A deletion of 234 was found in transcripts from brain or bone marrow cells. The GT to AT point mutation probably disrupted a splice donor site, thereby causing exon skipping. The 107 bp deletion could have resulted from skipping of a transmembrane region exon and the 234 bp deletion from skipping 3 exons. The 107 bp deletion would generate a stop codon 12 bp downstream because of a frame shift, whereas the larger deletion would still be in frame. Northern blot analysis indicated that mast cells from mutants have only 31-37% of the transcripts as mast cells derived from normal bone marrow, suggesting that the mutation may reduce efficiency and authenticity of transcription and splicing. [J:91867]

Allele Symbol		Pde6b^rd1
Allele Name		retinal degeneration 1
Common Name(s)		rd; rd-1; rd1; rodless retina;

Control Information

	Control
	+/+ from the colony

Considerations for Choosing Controls

Colony Maintenance

Diet Information	LabDiet® 5K52/5K67

Related Strains

Strains carrying Kit^W-v allele

000599 B6 x B6CBCa A^w-J/A-T(5;13)264Ca Kit^W-v/J

000194 B6.Cg-Lx Kit^W-v/J

000350 B6By.Cg-Kit^W-v Mitf^Mi-wh T/J

000049 C57BL/6J-Kit^W-v/J

View Strains carrying Kit^W-v (4 strains)

Strains carrying Kit^W allele

000164 B6.Cg-Kit^W/J

000092 FL/1Re-Kit^W/J

000692 WB/ReJ Kit^W/J

View Strains carrying Kit^W (3 strains)

Strains carrying Pde6b^rd1 allele

004202 B6.C3 Pde6b^rd1 Hps4^le/+ +-Lmx1a^dr-8J/J

000002 B6.C3-Pde6b^rd1 Hps4^le/J

001022 B6C3FeF1/J a/a

000652 BDP/J

000653 BUB/BnJ

002439 C3.129P2(B6)-B2m^tm1Unc/J

005494 C3.129S1(B6)-Grm1^rcw/J

000480 C3.MRL-Fas^lpr/J

001957 C3A Pde6b^rd1.O20/A-Prph2^Rd2/J

005973 C3Bir.129P2(B6)-Il10^C3Bir/LtJ

004326 C3Bir.129P2(B6)-Il10^tm1Cgn/Lt

003968 C3Bir.129P2(B6)-Il10^tm1Cgn/LtJ

001906 C3Ga.Cg-Cat^b/J

001904 C3H-Atcay^ji-hes/J

000659 C3H/HeJ

000784 C3H/HeJ-Fasl^gld/J

000509 C3H/HeJ-Lyst^bg-2J/J

002433 C3H/HeJ-Spnb4^qv-lnd2J/J

005972 C3H/HeJBirLtJ

001824 C3H/HeJSxJ

000635 C3H/HeOuJ

000474 C3H/HeSn

001431 C3H/HeSn-ocd/J

000661 C3H/HeSnJ

002235 C3H/HeSnJ-Ctnna2^cdf/J

002333 C3H/HeSnJ-gri/J

006435 C3HeB.SW-Soa^a/MonJ

000658 C3HeB/FeJ

001576 C3HeB/FeJ-Atp7b^tx-J/J

002588 C3HeB/FeJ-Eya1^bor/J

001533 C3HeB/FeJ-Mc1r^E-so Gli3^Xt-J/J

001886 C3HeB/FeJLe a/a-gnd/J

001908 C3HfB/BiJ

001502 C3Sn.B6-Epha4^rb/J

001547 C3Sn.Cg-Cm/J

000656 CBA/J

000813 CBA/J-Atp7a^Mo-pew/J

000660 DA/HuSnJ

000023 FL/1ReJ

000025 FL/4ReJ

003078 FVB-Tg(WapIgf1)39Dlr/J

003024 FVB.129P2(B6)-Fmr1^tm1Cgr/J

002539 FVB.129P2-Abcb4^tm1Bor/J

002935 FVB.129S2(B6)-Ccnd1^tm1Wbg/J

002953 FVB.Cg-Tg(MMTVTGFA)254Rjc/J

003170 FVB.Cg-Tg(Myh6-tTA)6Smbf/J

003257 FVB/N-Tg(GFAPGFP)14Mes/J

002374 FVB/N-Tg(MMTV-PyVT)634Mul/J

002856 FVB/N-Tg(TIE2-lacZ)182Sato/J

002384 FVB/N-Tg(UcpDta)1Kz/J

001800 FVB/NJ

003487 FVB/NJ-Tg(XGFAP-lacZ)3Mes/J

001491 FVB/NMob

000734 MOLD/RkJ

000550 MOLF/EiJ

002423 NON/ShiLtJ

000679 P/J

000680 PL/J

100299 PLSJLF1/J

000269 SB/LeJ

005651 SJL.AK-Thy1^a/TseJ

000686 SJL/J

000688 ST/bJ

004808 STOCK Mapt^tm1(EGFP)Klt Tg(MAPT)8cPdav/J

002648 STOCK a/a Cln6^nclf/J

000279 STOCK gr +/+ Ap3d1^mh/J

005965 STOCK Tg(Pomc1-cre)16Lowl/J

004770 SW.B6-Soa^b/J

002023 SWR.M-Emv21 Emv22/J

000689 SWR/J

000939 SWR/J-Clcn1^adr-mto/J

000692 WB/ReJ Kit^W/J

000693 WC/ReJ Kitl^Sl/J

100401 WCB6F1/J Kitl^Sl Kitl^Sl-d

View Strains carrying Pde6b^rd1 (74 strains)

Strains carrying other alleles of Kit

006564 B6(C)-Kit^W-41J Gusb^mps/BrkJ

000495 B6.C-H38^c/By-Kit^W-56J/J

000560 B6.C-H7^b/By Kit^W-50J/J

000122 B6.C3-Kit^W-44J/J

000991 B6.C58-Kit^W-57J/J

002283 B6.Cg-Kit^W-19H/EiJ

000133 B6.Cg-Kit^W-24J/J

000139 B6.Cg-Kit^W-25J/J

005051 B6.Cg-Kit^W-sh/HNihrJaeBsmJ

000171 B6.D2-Kit^W-45J/J

001563 B6.D2-Kit^W-73J/J

001177 B6.LP-Kit^W-49J/J

000627 C3H/HeJ-Kit^W-x/J

000847 C3Sn.B6-Kit^W-39J/J

000166 C57BL/6J-Kit^W-17J/J

000167 C57BL/6J-Kit^W-18J/J

000169 C57BL/6J-Kit^W-20J/J

000117 C57BL/6J-Kit^W-34J/J

000128 C57BL/6J-Kit^W-35J/J

000134 C57BL/6J-Kit^W-37J/J

000062 C57BL/6J-Kit^W-39J/J

000121 C57BL/6J-Kit^W-40J/J

000119 C57BL/6J-Kit^W-41J/J

000127 C57BL/6J-Kit^W-42J/J

000129 C57BL/6J-Kit^W-43J/J

000990 C57BL/6J-Kit^W-55J/J

001179 C57BL/6J-Kit^W-62J/J

000965 CBACa.C3-Kit^W-x/J

000993 NZB/BlNJ-Kit^W-59J/J

View Strains carrying other alleles of Kit (29 strains)

Strains carrying other alleles of Pde6b

004297 B6.CXB1-Pde6b^rd10/J

002802 C3.BLiA Pde6b⁺-Krd/J

001979 C3A.BLiA-Pde6b⁺.O20-Prph2^Rd2/J

001912 C3A.BLiA-Pde6b⁺/J

003648 C3Sn.BLiA-Pde6b⁺/Dn

004766 C57BL/6J-Pde6b^rd1-2J/J

004828 FVB.129P2-Pde6b⁺ Tyr^c-ch/AntJ

004808 STOCK Mapt^tm1(EGFP)Klt Tg(MAPT)8cPdav/J

View Strains carrying other alleles of Pde6b (8 strains)

Additional Web Information

Genetic Quality Control Annual Report
JAX Notes, Winter 1991; 444. Coat Colors of Anemic Mice.

Animal Health Reports

Room Number AX5

Research Applications

This mouse can be used to support research in many areas including:

Hematological Research
Anemia, Iron Deficiency and Transport Defects
Mast Cell Deficiency

Internal/Organ Research
Gastrointestinal Defects

Kit^W-v related

Cancer Research
Growth Factors/Receptors/Cytokines
Increased Tumor Incidence (Gonadal Tumors: ovarian)
Oncogenes

Dermatology Research
Color and White Spotting Defects

Developmental Biology Research
Neural Crest Defects

Endocrine Deficiency Research
Bone/Bone Marrow Defects
Gonad Defects
Skin Defects

Immunology and Inflammation Research
Immunodeficiency (Mast Cell Deficiency)

Mouse/Human Gene Homologs
piebaldism
synpolydactyly

Neurobiology Research
Receptor Defects
Vestibular and Hearing Defects

Reproductive Biology Research
Developmental Defects Affecting Gonads (germ cell deficient)
Fertility Defects
Gonadal Tumors (ovarian)

Research Tools
Immunology and Inflammation Research (Mast Cell Deficiency)

Sensorineural Research
Vestibular and Hearing Defects

Kit^W related

Cancer Research
Growth Factors/Receptors/Cytokines
Increased Tumor Incidence (Gonadal Tumors: ovarian)
Oncogenes

Dermatology Research
Color and White Spotting Defects

Developmental Biology Research
Neural Crest Defects

Endocrine Deficiency Research
Bone/Bone Marrow Defects
Gonad Defects
Skin Defects

Immunology and Inflammation Research
Immunodeficiency (Mast Cell Deficiency)

Mouse/Human Gene Homologs
piebaldism
synpolydactyly

Neurobiology Research
Receptor Defects
Vestibular and Hearing Defects

Reproductive Biology Research
Developmental Defects Affecting Gonads (germ cell deficient)
Fertility Defects
Gonadal Tumors (ovarian)

Research Tools
Immunology and Inflammation Research (Mast Cell Deficiency)

Sensorineural Research
Retinal Degeneration
Vestibular and Hearing Defects

Pde6b^rd1 related

Mouse/Human Gene Homologs
retinitis pigmentosa, autosomal recessive

Sensorineural Research
Retinal Degeneration

References

Selected Reference(s)

Arguello F; Furlanetto RW; Baggs RB; Graves BT; Harwell SE; Cohen HJ; Frantz CN. 1992. Incidence and distribution of experimental metastases in mutant mice with defective organ microenvironments (genotypes Sl/Sld and W/Wv). Cancer Res 52(8):2304-9. [PubMed: 1559233] [J:468]
Murphy ED. 1972. Hyperplastic and early neoplastic changes in the ovaries of mice after genic deletion of germ cells. J Natl Cancer Inst 48(5):1283-95. [PubMed: 4337905] [J:5274]
Nocka K; Tan JC; Chiu E; Chu TY; Ray P; Traktman P; Besmer P. 1990. Molecular bases of dominant negative and loss of function mutations at the murine c-kit/white spotting locus: W37, Wv, W41 and W. EMBO J 9(6):1805-13. [PubMed: 1693331] [J:10528]
Reis MM; Tsai MC; Schlegel PN; Feliciano M; Raffaelli R; Rosenwaks Z; Palermo GD. 2000. Xenogeneic transplantation of human spermatogonia. Zygote 8(2):97-105. [PubMed: 10857580] [J:109890]
Shyu H; Hsu S; Hsieh-Li H; Li H. 2001. A novel member of the RBCC family, Trif, expressed specifically in the spermatids of mouse testis. Mech Dev 108(1-2):213-6. [PubMed: 11578878] [J:71914]

Additional References

Price and Supply Information

Strain Name:	*WBB6F1/J-Kit^W/Kit^W-v/J*
Stock Number:	100410

Price Details

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Supply Details

Standard Supply	Level 2. Up to 100 mice. Larger quantities or custom orders arranged upon request.
Supply Notes	Shipped at a specific age in weeks. Mice at a precise age in days, littermates and retired breeders are also available. Strains that must be genotyped are not available until five to seven weeks of age. Genomic DNA is available for this strain from the Mouse DNA Resource.
Licensing	See General Terms and Conditions below
Control Information	View Control Information in Strain Details.

General Terms and Conditions

View JAX^® Mice & Services Conditions of Use.

The Jackson Laboratory's Genotype Promise

The Jackson Laboratory has rigorous genetic quality control and mutant gene genotyping programs to ensure the genetic background of JAX^® Mice strains as well as the genotypes of strains with identified molecular mutations. JAX^® Mice strains are only made available to researchers after meeting our standards. However, the phenotype of each strain may not be fully characterized and/or captured in the strain data sheets. Therefore, we cannot guarantee a strain's phenotype will meet all expectations. To ensure that JAX^® Mice will meet the needs of individual research projects or when requesting a strain that is new to your research, we suggest ordering and performing tests on a small number of mice to determine suitability for your particular project.

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Tel: 800.422.6423 or 207.288.5845
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Go to JAX^® Mice Query Form

000599	B6 x B6CBCa A^w-J/A-T(5;13)264Ca Kit^W-v/J
000194	B6.Cg-Lx Kit^W-v/J
000350	B6By.Cg-Kit^W-v Mitf^Mi-wh T/J
000049	C57BL/6J-Kit^W-v/J

000164	B6.Cg-Kit^W/J
000092	FL/1Re-Kit^W/J
000692	WB/ReJ Kit^W/J

004202	B6.C3 Pde6b^rd1 Hps4^le/+ +-Lmx1a^dr-8J/J
000002	B6.C3-Pde6b^rd1 Hps4^le/J
001022	B6C3FeF1/J a/a
000652	BDP/J
000653	BUB/BnJ
002439	C3.129P2(B6)-B2m^tm1Unc/J
005494	C3.129S1(B6)-Grm1^rcw/J
000480	C3.MRL-Fas^lpr/J
001957	C3A Pde6b^rd1.O20/A-Prph2^Rd2/J
005973	C3Bir.129P2(B6)-Il10^C3Bir/LtJ
004326	C3Bir.129P2(B6)-Il10^tm1Cgn/Lt
003968	C3Bir.129P2(B6)-Il10^tm1Cgn/LtJ
001906	C3Ga.Cg-Cat^b/J
001904	C3H-Atcay^ji-hes/J
000659	C3H/HeJ
000784	C3H/HeJ-Fasl^gld/J
000509	C3H/HeJ-Lyst^bg-2J/J
002433	C3H/HeJ-Spnb4^qv-lnd2J/J
005972	C3H/HeJBirLtJ
001824	C3H/HeJSxJ
000635	C3H/HeOuJ
000474	C3H/HeSn
001431	C3H/HeSn-ocd/J
000661	C3H/HeSnJ
002235	C3H/HeSnJ-Ctnna2^cdf/J
002333	C3H/HeSnJ-gri/J
006435	C3HeB.SW-Soa^a/MonJ
000658	C3HeB/FeJ
001576	C3HeB/FeJ-Atp7b^tx-J/J
002588	C3HeB/FeJ-Eya1^bor/J
001533	C3HeB/FeJ-Mc1r^E-so Gli3^Xt-J/J
001886	C3HeB/FeJLe a/a-gnd/J
001908	C3HfB/BiJ
001502	C3Sn.B6-Epha4^rb/J
001547	C3Sn.Cg-Cm/J
000656	CBA/J
000813	CBA/J-Atp7a^Mo-pew/J
000660	DA/HuSnJ
000023	FL/1ReJ
000025	FL/4ReJ
003078	FVB-Tg(WapIgf1)39Dlr/J
003024	FVB.129P2(B6)-Fmr1^tm1Cgr/J
002539	FVB.129P2-Abcb4^tm1Bor/J
002935	FVB.129S2(B6)-Ccnd1^tm1Wbg/J
002953	FVB.Cg-Tg(MMTVTGFA)254Rjc/J
003170	FVB.Cg-Tg(Myh6-tTA)6Smbf/J
003257	FVB/N-Tg(GFAPGFP)14Mes/J
002374	FVB/N-Tg(MMTV-PyVT)634Mul/J
002856	FVB/N-Tg(TIE2-lacZ)182Sato/J
002384	FVB/N-Tg(UcpDta)1Kz/J
001800	FVB/NJ
003487	FVB/NJ-Tg(XGFAP-lacZ)3Mes/J
001491	FVB/NMob
000734	MOLD/RkJ
000550	MOLF/EiJ
002423	NON/ShiLtJ
000679	P/J
000680	PL/J
100299	PLSJLF1/J
000269	SB/LeJ
005651	SJL.AK-Thy1^a/TseJ
000686	SJL/J
000688	ST/bJ
004808	STOCK Mapt^tm1(EGFP)Klt Tg(MAPT)8cPdav/J
002648	STOCK a/a Cln6^nclf/J
000279	STOCK gr +/+ Ap3d1^mh/J
005965	STOCK Tg(Pomc1-cre)16Lowl/J
004770	SW.B6-Soa^b/J
002023	SWR.M-Emv21 Emv22/J
000689	SWR/J
000939	SWR/J-Clcn1^adr-mto/J
000692	WB/ReJ Kit^W/J
000693	WC/ReJ Kitl^Sl/J
100401	WCB6F1/J Kitl^Sl Kitl^Sl-d

006564	B6(C)-Kit^W-41J Gusb^mps/BrkJ
000495	B6.C-H38^c/By-Kit^W-56J/J
000560	B6.C-H7^b/By Kit^W-50J/J
000122	B6.C3-Kit^W-44J/J
000991	B6.C58-Kit^W-57J/J
002283	B6.Cg-Kit^W-19H/EiJ
000133	B6.Cg-Kit^W-24J/J
000139	B6.Cg-Kit^W-25J/J
005051	B6.Cg-Kit^W-sh/HNihrJaeBsmJ
000171	B6.D2-Kit^W-45J/J
001563	B6.D2-Kit^W-73J/J
001177	B6.LP-Kit^W-49J/J
000627	C3H/HeJ-Kit^W-x/J
000847	C3Sn.B6-Kit^W-39J/J
000166	C57BL/6J-Kit^W-17J/J
000167	C57BL/6J-Kit^W-18J/J
000169	C57BL/6J-Kit^W-20J/J
000117	C57BL/6J-Kit^W-34J/J
000128	C57BL/6J-Kit^W-35J/J
000134	C57BL/6J-Kit^W-37J/J
000062	C57BL/6J-Kit^W-39J/J
000121	C57BL/6J-Kit^W-40J/J
000119	C57BL/6J-Kit^W-41J/J
000127	C57BL/6J-Kit^W-42J/J
000129	C57BL/6J-Kit^W-43J/J
000990	C57BL/6J-Kit^W-55J/J
001179	C57BL/6J-Kit^W-62J/J
000965	CBACa.C3-Kit^W-x/J
000993	NZB/BlNJ-Kit^W-59J/J

004297	B6.CXB1-Pde6b^rd10/J
002802	C3.BLiA Pde6b⁺-Krd/J
001979	C3A.BLiA-Pde6b⁺.O20-Prph2^Rd2/J
001912	C3A.BLiA-Pde6b⁺/J
003648	C3Sn.BLiA-Pde6b⁺/Dn
004766	C57BL/6J-Pde6b^rd1-2J/J
004828	FVB.129P2-Pde6b⁺ Tyr^c-ch/AntJ
004808	STOCK Mapt^tm1(EGFP)Klt Tg(MAPT)8cPdav/J

Strain Name:

WBB6F1/J-KitW/KitW-v/J

Stock Number:

100410

Availability:

Level 2

General Terms and Conditions

Product Information

Strain Details

KitW/KitW-v

KitW/KitW-v

KitW/KitW-v

Gene & Allele Details

Control Information

Colony Maintenance

Related Strains

Additional Web Information

Animal Health Reports

Research Applications

References

Price and Supply Information

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Supply Details

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The Jackson Laboratory's Genotype Promise

WBB6F1/J-Kit^W/Kit^W-v/J

Kit^W/Kit^W-v

Kit^W/Kit^W-v

Kit^W/Kit^W-v