Description

Strain Information

Former Names B6129F1/J    (Changed: 24-JAN-06 ) B6129PF1/J    (Changed: 24-JAN-06 ) Type *F1 Hybrid; Additional information on Hybrid Strains. Visit our online Nomenclature tutorial. Breeding Considerations This strain is an exceptional breeder. Species laboratory mouse Parentals C57BL/6J (000664) Female x 129P3/J (000690) Male H2 Haplotype b/bc

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Appearance
white-bellied agouti
Related Genotype: A^w/a Oca2^p Tyr^c/+ + or A^w/a Oca2^p Tyr^c-ch/+ +

Description
These F1 (first filial generation) hybrid mice are the offspring of a cross between C57BL/6J females (B6) and 129P3/J males (129P). F1 hybrid mice are heterozygous at all loci (assuming the parental strains have different alleles), and like inbred mice they are genetically and phenotypically uniform. F1 hybrids are often used for hybrid vigor, as a background for some deleterious mutations, for tissue transplantation, to determine the mode of inheritance, to create or enhance expression of polygenic diseases, and to provide physiological buffering (present a broader array of responses to various stresses). B6129 hybrid crosses often provide approximate controls for genetically engineered strains that were generated with 129-derived embryonic stem cells and maintained on a mixed B6;129 background.

Development
These F1 (first filial generation) hybrid mice are the offspring of a cross between C57BL/6J females (B6) and 129P3/J males (129P).

Related Strains

F1 Hybrid

100409	B6129PF1/J-Aw-J/Aw
101043	B6129SF1/J
100002	B6AF1/J
100010	B6C3F1/J
001022	B6C3FeF1/J a/a
001201	B6CBACaF1/J-Aw-J/A
100011	B6CBAF1/J
100006	B6D2F1/J
001875	B6EiC3SnF1/J
019019	B6FVBF1/J
100012	B6SJLF1/J
100004	C3D2F1/J
001203	C3FeB6F1/J A/Aw-J
100003	CAF1/J
100007	CB6F1/J
100009	CByB6F1/J
100008	NZBWF1/J

View F1 Hybrid     (17 strains)

Phenotype

Phenotype Information

Currently there is no phenotype information for this strain.

Genes & Alleles

Gene & Allele Information provided by MGI

Currently there are no related genes or alleles for this strain.

Genotyping

Genotyping Information

Hybrid mice are produced from breeding two different inbred strains together (F1) or the breeding of hybrids together (F2); no genotyping required.

Helpful Links

Genotyping resources and troubleshooting

References

References provided by MGI

Currently there are no available references for this strain.

Health & husbandry

Health & Colony Maintenance Information

Animal Health Reports

Room Number           AX27

Colony Maintenance

Breeding Considerations	This strain is an exceptional breeder.
Diet Information	LabDiet® 5K52/5K67

Pricing and Purchasing

Pricing, Supply Level & Notes, Controls

General Supply Notes

• Genomic DNA is available for this strain from the Mouse DNA Resource.

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The Jackson Laboratory's Genotype Promise

The Jackson Laboratory has rigorous genetic quality control and mutant gene genotyping programs to ensure the genetic background of JAX^® Mice strains as well as the genotypes of strains with identified molecular mutations. JAX^® Mice strains are only made available to researchers after meeting our standards. However, the phenotype of each strain may not be fully characterized and/or captured in the strain data sheets. Therefore, we cannot guarantee a strain's phenotype will meet all expectations. To ensure that JAX^® Mice will meet the needs of individual research projects or when requesting a strain that is new to your research, we suggest ordering and performing tests on a small number of mice to determine suitability for your particular project.

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